FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2666, 255 aa 1>>>pF1KE2666 255 - 255 aa - 255 aa Library: /omim/omim.rfq.tfa 61127809 residues in 85815 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2293+/-0.000341; mu= 6.3060+/- 0.021 mean_var=116.1159+/-22.728, 0's: 0 Z-trim(117.4): 2 B-trim: 0 in 0/58 Lambda= 0.119022 statistics sampled from 29505 (29507) to 29505 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.344), width: 16 Scan time: 6.310 The best scores are: opt bits E(85815) NP_659497 (OMIM: 616673) spindle and kinetochore-a ( 255) 1661 295.6 5.7e-80 NP_001034624 (OMIM: 616673) spindle and kinetochor ( 255) 1661 295.6 5.7e-80 >>NP_659497 (OMIM: 616673) spindle and kinetochore-assoc (255 aa) initn: 1661 init1: 1661 opt: 1661 Z-score: 1556.7 bits: 295.6 E(85815): 5.7e-80 Smith-Waterman score: 1661; 100.0% identity (100.0% similar) in 255 aa overlap (1-255:1-255) 10 20 30 40 50 60 pF1KE2 MASSDLEQLCSHVNEKIGNIKKTLSLRNCGQEPTLKTVLNKIGDEIIVINELLNKLELEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_659 MASSDLEQLCSHVNEKIGNIKKTLSLRNCGQEPTLKTVLNKIGDEIIVINELLNKLELEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QYQEQTNNSLKELCESLEEDYKDIEHLKENVPSHLPQVTVTQSCVKGSDLDPEEPIKVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_659 QYQEQTNNSLKELCESLEEDYKDIEHLKENVPSHLPQVTVTQSCVKGSDLDPEEPIKVEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 PEPVKKPPKEQRSIKEMPFITCDEFNGVPSYMKSRLTYNQINDVIKEINKAVISKYKILH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_659 PEPVKKPPKEQRSIKEMPFITCDEFNGVPSYMKSRLTYNQINDVIKEINKAVISKYKILH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 QPKKSMNSVTRNLYHRFIDEETKDTKGRYFIVEADIKEFTTLKADKKFHVLLNILRHCRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_659 QPKKSMNSVTRNLYHRFIDEETKDTKGRYFIVEADIKEFTTLKADKKFHVLLNILRHCRR 190 200 210 220 230 240 250 pF1KE2 LSEVRGGGLTRYVIT ::::::::::::::: NP_659 LSEVRGGGLTRYVIT 250 >>NP_001034624 (OMIM: 616673) spindle and kinetochore-as (255 aa) initn: 1661 init1: 1661 opt: 1661 Z-score: 1556.7 bits: 295.6 E(85815): 5.7e-80 Smith-Waterman score: 1661; 100.0% identity (100.0% similar) in 255 aa overlap (1-255:1-255) 10 20 30 40 50 60 pF1KE2 MASSDLEQLCSHVNEKIGNIKKTLSLRNCGQEPTLKTVLNKIGDEIIVINELLNKLELEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASSDLEQLCSHVNEKIGNIKKTLSLRNCGQEPTLKTVLNKIGDEIIVINELLNKLELEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QYQEQTNNSLKELCESLEEDYKDIEHLKENVPSHLPQVTVTQSCVKGSDLDPEEPIKVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYQEQTNNSLKELCESLEEDYKDIEHLKENVPSHLPQVTVTQSCVKGSDLDPEEPIKVEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 PEPVKKPPKEQRSIKEMPFITCDEFNGVPSYMKSRLTYNQINDVIKEINKAVISKYKILH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEPVKKPPKEQRSIKEMPFITCDEFNGVPSYMKSRLTYNQINDVIKEINKAVISKYKILH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 QPKKSMNSVTRNLYHRFIDEETKDTKGRYFIVEADIKEFTTLKADKKFHVLLNILRHCRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPKKSMNSVTRNLYHRFIDEETKDTKGRYFIVEADIKEFTTLKADKKFHVLLNILRHCRR 190 200 210 220 230 240 250 pF1KE2 LSEVRGGGLTRYVIT ::::::::::::::: NP_001 LSEVRGGGLTRYVIT 250 255 residues in 1 query sequences 61127809 residues in 85815 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Jan 12 11:37:20 2017 done: Thu Jan 12 11:37:21 2017 Total Scan time: 6.310 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]