Result of FASTA (omim) for
pF1KE2684
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2684, 217 aa
1>>>pF1KE2684 217 - 217 aa - 217 aa
Library: /omim/omim.rfq.tfa
61718354 residues in 86699 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3053+/-0.000294; mu= 13.8267+/- 0.019
mean_var=59.3135+/-11.796, 0's: 0 Z-trim(117.4): 28 B-trim: 0 in 0/57
Lambda= 0.166532
statistics sampled from 29631 (29659) to 29631 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.342), width: 16
Scan time: 4.390
The best scores are: opt bits E(86699)
NP_001959 (OMIM: 133440,615091) eukaryotic transla ( 217) 1492 366.2 2.4e-101
NP_001124150 (OMIM: 133440,615091) eukaryotic tran ( 237) 1454 357.1 1.4e-98
NP_001317946 (OMIM: 133440,615091) eukaryotic tran ( 245) 1454 357.1 1.5e-98
NP_001124151 (OMIM: 133440,615091) eukaryotic tran ( 248) 935 232.4 5.2e-61
NP_001263265 (OMIM: 605895) eukaryotic translation ( 234) 441 113.7 2.6e-25
NP_001317131 (OMIM: 605895) eukaryotic translation ( 240) 440 113.5 3.2e-25
NP_004837 (OMIM: 605895) eukaryotic translation in ( 245) 440 113.5 3.2e-25
NP_001269887 (OMIM: 605895) eukaryotic translation ( 236) 433 111.8 1e-24
NP_001263266 (OMIM: 605895) eukaryotic translation ( 189) 371 96.8 2.5e-20
NP_001317130 (OMIM: 605895) eukaryotic translation ( 200) 370 96.6 3.1e-20
NP_001317132 (OMIM: 605895) eukaryotic translation ( 191) 363 94.9 9.6e-20
NP_001128123 (OMIM: 609896) eukaryotic translation ( 224) 280 75.0 1.1e-13
NP_775495 (OMIM: 609896) eukaryotic translation in ( 118) 175 49.7 2.5e-06
NP_001128121 (OMIM: 609896) eukaryotic translation ( 118) 175 49.7 2.5e-06
XP_016861769 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.7 2.5e-06
XP_016861771 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.7 2.5e-06
XP_016861768 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.7 2.5e-06
XP_016861770 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.7 2.5e-06
XP_016861767 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.7 2.5e-06
NP_001269815 (OMIM: 609896) eukaryotic translation ( 118) 175 49.7 2.5e-06
NP_001128122 (OMIM: 609896) eukaryotic translation ( 118) 175 49.7 2.5e-06
>>NP_001959 (OMIM: 133440,615091) eukaryotic translation (217 aa)
initn: 1492 init1: 1492 opt: 1492 Z-score: 1940.6 bits: 366.2 E(86699): 2.4e-101
Smith-Waterman score: 1492; 99.5% identity (100.0% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KE2 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIG
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIG
130 140 150 160 170 180
190 200 210
pF1KE2 RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
:::::::::::::::::::::::::::::::::::::
NP_001 RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
190 200 210
>>NP_001124150 (OMIM: 133440,615091) eukaryotic translat (237 aa)
initn: 1454 init1: 1454 opt: 1454 Z-score: 1890.7 bits: 357.1 E(86699): 1.4e-98
Smith-Waterman score: 1454; 99.5% identity (100.0% similar) in 211 aa overlap (7-217:27-237)
10 20 30 40
pF1KE2 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQ
::::::::::::::::::::::::::::::::::
NP_001 MLDLTSRGQVGTSRRMAEAACSAHFLETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 NRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 MWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_001 MWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKG
130 140 150 160 170 180
170 180 190 200 210
pF1KE2 DKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
190 200 210 220 230
>>NP_001317946 (OMIM: 133440,615091) eukaryotic translat (245 aa)
initn: 1454 init1: 1454 opt: 1454 Z-score: 1890.5 bits: 357.1 E(86699): 1.5e-98
Smith-Waterman score: 1454; 99.5% identity (100.0% similar) in 211 aa overlap (7-217:35-245)
10 20 30
pF1KE2 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIK
::::::::::::::::::::::::::::::
NP_001 QNKKERKKMRAEDGENDAIKKQAESLRESQETTPTPNPPTTEEEKTESNQEVANPEHYIK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE2 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 GIEPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNV
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 GIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE2 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFV
190 200 210 220 230 240
pF1KE2 V
:
NP_001 V
>>NP_001124151 (OMIM: 133440,615091) eukaryotic translat (248 aa)
initn: 1478 init1: 935 opt: 935 Z-score: 1216.5 bits: 232.4 E(86699): 5.2e-61
Smith-Waterman score: 1420; 87.1% identity (87.5% similar) in 248 aa overlap (1-217:1-248)
10 20 30 40 50 60
pF1KE2 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
70 80 90 100 110 120
130 140
pF1KE2 QRRSDLNRFWLET-------------------------------LLCLIGESFDDYSDDV
::::::.:::::: ::::::::::::::::
NP_001 QRRSDLDRFWLETRWDLAMLPRLVSNFWPQVILPLQPPKVLELQLLCLIGESFDDYSDDV
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE2 CGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGS
190 200 210 220 230 240
210
pF1KE2 TTKNRFVV
::::::::
NP_001 TTKNRFVV
>>NP_001263265 (OMIM: 605895) eukaryotic translation ini (234 aa)
initn: 368 init1: 203 opt: 441 Z-score: 575.4 bits: 113.7 E(86699): 2.6e-25
Smith-Waterman score: 443; 33.8% identity (67.6% similar) in 207 aa overlap (18-213:29-229)
10 20 30 40
pF1KE2 MATVEPETTPTPNPPTTEEEKTE--SNQEVANPEHYI----KHPLQNRW
:.:::: .:: .. . . .:::: .
NP_001 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNY
10 20 30 40 50 60
50 60 70 80 90
pF1KE2 ALWFFKND-----KSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGI
..:. . .:.... :.. :. : .::.:: .:.:. ..: :. :::.::
NP_001 TFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 EPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRA
.:::::. :: ::.:.: : :.. .: : . .: ..::.: ....:::::.::
NP_001 KPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGEQFM-VGEEICGAVVSVRF
130 140 150 160 170
160 170 180 190 200 210
pF1KE2 KGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
. : :.::. .. ....: . .. :.:::. .. :..:.:. :..:. .:
NP_001 QEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSI-KDNSSFRNTKITL
180 190 200 210 220 230
>>NP_001317131 (OMIM: 605895) eukaryotic translation ini (240 aa)
initn: 364 init1: 203 opt: 440 Z-score: 574.0 bits: 113.5 E(86699): 3.2e-25
Smith-Waterman score: 442; 32.9% identity (65.7% similar) in 210 aa overlap (18-216:24-228)
10 20 30 40
pF1KE2 MATVEPETTPTPNPPTTEEEKTE--SNQEVANPEHYI----KHPLQNRWALWFF
:.:::: .:: .. . . .:::: ...:.
NP_001 MSLKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNYTFWYS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 KND-----KSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWE
. .:.... :.. :. : .::.:: .:.:. ..: :. :::.::.::::
NP_001 RRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 DEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKI
:. :: ::.:.: : :.. .: : . .: ..::.: ....:::::.:: . : :
NP_001 DDANKNGGKWIIRL----RKGLASRCWENLILAMLGEQFM-VGEEICGAVVSVRFQEDII
130 140 150 160 170
170 180 190 200 210
pF1KE2 AIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
.::. .. ....: . .. :.:::. .. :..:.:. : .:..
NP_001 SIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQNLWKP
180 190 200 210 220 230
NP_001 RLNVP
240
>>NP_004837 (OMIM: 605895) eukaryotic translation initia (245 aa)
initn: 364 init1: 203 opt: 440 Z-score: 573.8 bits: 113.5 E(86699): 3.2e-25
Smith-Waterman score: 442; 32.9% identity (65.7% similar) in 210 aa overlap (18-216:29-233)
10 20 30 40
pF1KE2 MATVEPETTPTPNPPTTEEEKTE--SNQEVANPEHYI----KHPLQNRW
:.:::: .:: .. . . .:::: .
NP_004 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNY
10 20 30 40 50 60
50 60 70 80 90
pF1KE2 ALWFFKND-----KSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGI
..:. . .:.... :.. :. : .::.:: .:.:. ..: :. :::.::
NP_004 TFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 EPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRA
.:::::. :: ::.:.: : :.. .: : . .: ..::.: ....:::::.::
NP_004 KPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGEQFM-VGEEICGAVVSVRF
130 140 150 160 170
160 170 180 190 200 210
pF1KE2 KGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
. : :.::. .. ....: . .. :.:::. .. :..:.:. : .:..
NP_004 QEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQ
180 190 200 210 220 230
NP_004 NLWKPRLNVP
240
>>NP_001269887 (OMIM: 605895) eukaryotic translation ini (236 aa)
initn: 364 init1: 203 opt: 433 Z-score: 565.0 bits: 111.8 E(86699): 1e-24
Smith-Waterman score: 435; 34.0% identity (67.5% similar) in 197 aa overlap (18-203:29-220)
10 20 30 40
pF1KE2 MATVEPETTPTPNPPTTEEEKTE--SNQEVANPEHYI----KHPLQNRW
:.:::: .:: .. . . .:::: .
NP_001 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNY
10 20 30 40 50 60
50 60 70 80 90
pF1KE2 ALWFFKND-----KSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGI
..:. . .:.... :.. :. : .::.:: .:.:. ..: :. :::.::
NP_001 TFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 EPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRA
.:::::. :: ::.:.: : :.. .: : . .: ..::.: ....:::::.::
NP_001 KPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGEQFM-VGEEICGAVVSVRF
130 140 150 160 170
160 170 180 190 200 210
pF1KE2 KGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
. : :.::. .. ....: . .. :.:::. .. :..:.:.
NP_001 QEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKAWEEFHGLVNSSG
180 190 200 210 220 230
NP_001 R
>>NP_001263266 (OMIM: 605895) eukaryotic translation ini (189 aa)
initn: 370 init1: 203 opt: 371 Z-score: 486.0 bits: 96.8 E(86699): 2.5e-20
Smith-Waterman score: 371; 36.2% identity (68.7% similar) in 163 aa overlap (51-213:29-184)
30 40 50 60 70 80
pF1KE2 KTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQ
.: :: . . . :: ::.:: .:.:.
NP_001 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSK-RKVEQFWRFYSHMV
10 20 30 40 50
90 100 110 120 130 140
pF1KE2 LSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGE
..: :. :::.::.:::::. :: ::.:.: : :.. .: : . .: ..::
NP_001 RPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGE
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE2 SFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSH
.: ....:::::.:: . : :.::. .. ....: . .. :.:::. .. :..:
NP_001 QFM-VGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTH
120 130 140 150 160 170
210
pF1KE2 ADTATKSGSTTKNRFVV
.:. :..:. .:
NP_001 TDSI-KDNSSFRNTKITL
180
>>NP_001317130 (OMIM: 605895) eukaryotic translation ini (200 aa)
initn: 348 init1: 203 opt: 370 Z-score: 484.3 bits: 96.6 E(86699): 3.1e-20
Smith-Waterman score: 370; 34.9% identity (66.3% similar) in 166 aa overlap (51-216:29-188)
30 40 50 60 70 80
pF1KE2 KTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQ
.: :: . . . :: ::.:: .:.:.
NP_001 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSK-RKVEQFWRFYSHMV
10 20 30 40 50
90 100 110 120 130 140
pF1KE2 LSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGE
..: :. :::.::.:::::. :: ::.:.: : :.. .: : . .: ..::
NP_001 RPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGE
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE2 SFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSH
.: ....:::::.:: . : :.::. .. ....: . .. :.:::. .. :..:
NP_001 QFM-VGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTH
120 130 140 150 160 170
210
pF1KE2 ADTATKSGSTTKNRFVV
.:. : .:..
NP_001 TDSIKMPGRLGPQRLLFQNLWKPRLNVP
180 190 200
217 residues in 1 query sequences
61718354 residues in 86699 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Apr 21 11:09:02 2017 done: Fri Apr 21 11:09:02 2017
Total Scan time: 4.390 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]