FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2729, 465 aa 1>>>pF1KE2729 465 - 465 aa - 465 aa Library: /omim/omim.rfq.tfa 65089639 residues in 91964 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.9084+/-0.000456; mu= -9.4695+/- 0.028 mean_var=515.8338+/-118.259, 0's: 0 Z-trim(118.7): 96 B-trim: 1934 in 1/56 Lambda= 0.056470 statistics sampled from 33077 (33185) to 33077 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.361), width: 16 Scan time: 4.670 The best scores are: opt bits E(91964) NP_003675 (OMIM: 606724) MAP kinase-interacting se ( 453) 3045 263.4 9.9e-70 XP_006711078 (OMIM: 606724) MAP kinase-interacting ( 329) 1794 161.3 3.9e-39 XP_006711076 (OMIM: 606724) MAP kinase-interacting ( 329) 1794 161.3 3.9e-39 XP_006711077 (OMIM: 606724) MAP kinase-interacting ( 329) 1794 161.3 3.9e-39 XP_024306279 (OMIM: 606724) MAP kinase-interacting ( 369) 1794 161.4 4.2e-39 XP_006711070 (OMIM: 606724) MAP kinase-interacting ( 369) 1794 161.4 4.2e-39 NP_001129025 (OMIM: 606724) MAP kinase-interacting ( 412) 1794 161.4 4.5e-39 XP_024306278 (OMIM: 606724) MAP kinase-interacting ( 412) 1794 161.4 4.5e-39 XP_024306277 (OMIM: 606724) MAP kinase-interacting ( 412) 1794 161.4 4.5e-39 XP_024306276 (OMIM: 606724) MAP kinase-interacting ( 412) 1794 161.4 4.5e-39 XP_006711065 (OMIM: 606724) MAP kinase-interacting ( 418) 1794 161.4 4.5e-39 XP_006711064 (OMIM: 606724) MAP kinase-interacting ( 418) 1794 161.4 4.5e-39 XP_006711066 (OMIM: 606724) MAP kinase-interacting ( 418) 1794 161.4 4.5e-39 XP_006711063 (OMIM: 606724) MAP kinase-interacting ( 424) 1794 161.4 4.6e-39 XP_016858142 (OMIM: 606724) MAP kinase-interacting ( 427) 1794 161.4 4.6e-39 XP_016858141 (OMIM: 606724) MAP kinase-interacting ( 427) 1794 161.4 4.6e-39 NP_951009 (OMIM: 605069) MAP kinase-interacting se ( 465) 1322 123.0 1.8e-27 XP_024306281 (OMIM: 606724) MAP kinase-interacting ( 335) 1222 114.7 4.2e-25 XP_024306282 (OMIM: 606724) MAP kinase-interacting ( 335) 1222 114.7 4.2e-25 XP_024306280 (OMIM: 606724) MAP kinase-interacting ( 335) 1222 114.7 4.2e-25 XP_016858151 (OMIM: 606724) MAP kinase-interacting ( 341) 1222 114.7 4.3e-25 XP_016858149 (OMIM: 606724) MAP kinase-interacting ( 341) 1222 114.7 4.3e-25 XP_016858150 (OMIM: 606724) MAP kinase-interacting ( 341) 1222 114.7 4.3e-25 XP_016858148 (OMIM: 606724) MAP kinase-interacting ( 347) 1222 114.7 4.3e-25 NP_060042 (OMIM: 605069) MAP kinase-interacting se ( 414) 1147 108.7 3.3e-23 XP_024307239 (OMIM: 605069) MAP kinase-interacting ( 459) 1147 108.8 3.5e-23 XP_016867813 (OMIM: 172470) phosphorylase b kinase ( 432) 339 42.9 0.0022 >>NP_003675 (OMIM: 606724) MAP kinase-interacting serine (453 aa) initn: 3045 init1: 3045 opt: 3045 Z-score: 1373.4 bits: 263.4 E(91964): 9.9e-70 Smith-Waterman score: 3045; 100.0% identity (100.0% similar) in 453 aa overlap (13-465:1-453) 10 20 30 40 50 60 pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY :::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 70 80 90 100 110 120 pF1KE2 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE2 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE2 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE2 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE2 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE2 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL 350 360 370 380 390 400 430 440 450 460 pF1KE2 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL ::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL 410 420 430 440 450 >>XP_006711078 (OMIM: 606724) MAP kinase-interacting ser (329 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 824.2 bits: 161.3 E(91964): 3.9e-39 Smith-Waterman score: 1912; 87.8% identity (87.8% similar) in 335 aa overlap (131-465:36-329) 110 120 130 140 150 160 pF1KE2 CQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDF :::::::::::::::::::::::::::::: XP_006 PSKSSRNKQGTVGVGCFERWRRCISVRETSSILAHIQKQKHFNEREASRVVRDVAAALDF 10 20 30 40 50 60 170 180 190 200 210 220 pF1KE2 LHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCE :::: ::::::::::::::: XP_006 LHTK-----------------------------------------GIAHRDLKPENILCE 70 80 230 240 250 260 270 280 pF1KE2 SPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDK 90 100 110 120 130 140 290 300 310 320 330 340 pF1KE2 RCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDW 150 160 170 180 190 200 350 360 370 380 390 400 pF1KE2 AHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTL 210 220 230 240 250 260 410 420 430 440 450 460 pF1KE2 FAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRS 270 280 290 300 310 320 pF1KE2 PPTAL ::::: XP_006 PPTAL >>XP_006711076 (OMIM: 606724) MAP kinase-interacting ser (329 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 824.2 bits: 161.3 E(91964): 3.9e-39 Smith-Waterman score: 1912; 87.8% identity (87.8% similar) in 335 aa overlap (131-465:36-329) 110 120 130 140 150 160 pF1KE2 CQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDF :::::::::::::::::::::::::::::: XP_006 PSKSSRNKQGTVGVGCFERWRRCISVRETSSILAHIQKQKHFNEREASRVVRDVAAALDF 10 20 30 40 50 60 170 180 190 200 210 220 pF1KE2 LHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCE :::: ::::::::::::::: XP_006 LHTK-----------------------------------------GIAHRDLKPENILCE 70 80 230 240 250 260 270 280 pF1KE2 SPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDK 90 100 110 120 130 140 290 300 310 320 330 340 pF1KE2 RCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDW 150 160 170 180 190 200 350 360 370 380 390 400 pF1KE2 AHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTL 210 220 230 240 250 260 410 420 430 440 450 460 pF1KE2 FAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRS 270 280 290 300 310 320 pF1KE2 PPTAL ::::: XP_006 PPTAL >>XP_006711077 (OMIM: 606724) MAP kinase-interacting ser (329 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 824.2 bits: 161.3 E(91964): 3.9e-39 Smith-Waterman score: 1912; 87.8% identity (87.8% similar) in 335 aa overlap (131-465:36-329) 110 120 130 140 150 160 pF1KE2 CQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDF :::::::::::::::::::::::::::::: XP_006 PSKSSRNKQGTVGVGCFERWRRCISVRETSSILAHIQKQKHFNEREASRVVRDVAAALDF 10 20 30 40 50 60 170 180 190 200 210 220 pF1KE2 LHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCE :::: ::::::::::::::: XP_006 LHTK-----------------------------------------GIAHRDLKPENILCE 70 80 230 240 250 260 270 280 pF1KE2 SPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDK 90 100 110 120 130 140 290 300 310 320 330 340 pF1KE2 RCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDW 150 160 170 180 190 200 350 360 370 380 390 400 pF1KE2 AHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTL 210 220 230 240 250 260 410 420 430 440 450 460 pF1KE2 FAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRS 270 280 290 300 310 320 pF1KE2 PPTAL ::::: XP_006 PPTAL >>XP_024306279 (OMIM: 606724) MAP kinase-interacting ser (369 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 823.6 bits: 161.4 E(91964): 4.2e-39 Smith-Waterman score: 2267; 86.3% identity (87.5% similar) in 408 aa overlap (58-465:4-369) 30 40 50 60 70 80 pF1KE2 RKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHS :. . :: : .: ..:::::::::: XP_024 MVTGGGRRSGGAGPLTPCQE-SLKIIEKQAGHS 10 20 30 90 100 110 120 130 140 pF1KE2 RSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 RSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREA 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE2 SRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGI ::::::::::::::::: :: XP_024 SRVVRDVAAALDFLHTK-----------------------------------------GI 100 110 210 220 230 240 250 260 pF1KE2 AHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 AHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEV 120 130 140 150 160 170 270 280 290 300 310 320 pF1KE2 VEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 VEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFES 180 190 200 210 220 230 330 340 350 360 370 380 pF1KE2 IQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 IQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQ 240 250 260 270 280 290 390 400 410 420 430 440 pF1KE2 VLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 VLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARR 300 310 320 330 340 350 450 460 pF1KE2 RALAQAGRGEDRSPPTAL :::::::::::::::::: XP_024 RALAQAGRGEDRSPPTAL 360 >>XP_006711070 (OMIM: 606724) MAP kinase-interacting ser (369 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 823.6 bits: 161.4 E(91964): 4.2e-39 Smith-Waterman score: 2267; 86.3% identity (87.5% similar) in 408 aa overlap (58-465:4-369) 30 40 50 60 70 80 pF1KE2 RKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHS :. . :: : .: ..:::::::::: XP_006 MVTGGGRRSGGAGPLTPCQE-SLKIIEKQAGHS 10 20 30 90 100 110 120 130 140 pF1KE2 RSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREA 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE2 SRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGI ::::::::::::::::: :: XP_006 SRVVRDVAAALDFLHTK-----------------------------------------GI 100 110 210 220 230 240 250 260 pF1KE2 AHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEV 120 130 140 150 160 170 270 280 290 300 310 320 pF1KE2 VEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFES 180 190 200 210 220 230 330 340 350 360 370 380 pF1KE2 IQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQ 240 250 260 270 280 290 390 400 410 420 430 440 pF1KE2 VLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARR 300 310 320 330 340 350 450 460 pF1KE2 RALAQAGRGEDRSPPTAL :::::::::::::::::: XP_006 RALAQAGRGEDRSPPTAL 360 >>NP_001129025 (OMIM: 606724) MAP kinase-interacting ser (412 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 823.1 bits: 161.4 E(91964): 4.5e-39 Smith-Waterman score: 2682; 90.9% identity (90.9% similar) in 453 aa overlap (13-465:1-412) 10 20 30 40 50 60 pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 70 80 90 100 110 120 pF1KE2 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE2 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS :::::::::::::::::::::::::::::::::::::::::::: NP_001 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTK---------------- 110 120 130 140 150 190 200 210 220 230 240 pF1KE2 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK ::::::::::::::::::::::::::::::::::: NP_001 -------------------------GIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK 160 170 180 250 260 270 280 290 300 pF1KE2 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP 190 200 210 220 230 240 310 320 330 340 350 360 pF1KE2 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK 250 260 270 280 290 300 370 380 390 400 410 420 pF1KE2 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL 310 320 330 340 350 360 430 440 450 460 pF1KE2 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL ::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL 370 380 390 400 410 >>XP_024306278 (OMIM: 606724) MAP kinase-interacting ser (412 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 823.1 bits: 161.4 E(91964): 4.5e-39 Smith-Waterman score: 2682; 90.9% identity (90.9% similar) in 453 aa overlap (13-465:1-412) 10 20 30 40 50 60 pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY :::::::::::::::::::::::::::::::::::::::::::::::: XP_024 MGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 70 80 90 100 110 120 pF1KE2 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE2 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS :::::::::::::::::::::::::::::::::::::::::::: XP_024 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTK---------------- 110 120 130 140 150 190 200 210 220 230 240 pF1KE2 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK ::::::::::::::::::::::::::::::::::: XP_024 -------------------------GIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK 160 170 180 250 260 270 280 290 300 pF1KE2 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP 190 200 210 220 230 240 310 320 330 340 350 360 pF1KE2 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK 250 260 270 280 290 300 370 380 390 400 410 420 pF1KE2 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL 310 320 330 340 350 360 430 440 450 460 pF1KE2 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL ::::::::::::::::::::::::::::::::::::::::::::: XP_024 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL 370 380 390 400 410 >>XP_024306277 (OMIM: 606724) MAP kinase-interacting ser (412 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 823.1 bits: 161.4 E(91964): 4.5e-39 Smith-Waterman score: 2682; 90.9% identity (90.9% similar) in 453 aa overlap (13-465:1-412) 10 20 30 40 50 60 pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY :::::::::::::::::::::::::::::::::::::::::::::::: XP_024 MGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 70 80 90 100 110 120 pF1KE2 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE2 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS :::::::::::::::::::::::::::::::::::::::::::: XP_024 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTK---------------- 110 120 130 140 150 190 200 210 220 230 240 pF1KE2 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK ::::::::::::::::::::::::::::::::::: XP_024 -------------------------GIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK 160 170 180 250 260 270 280 290 300 pF1KE2 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP 190 200 210 220 230 240 310 320 330 340 350 360 pF1KE2 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK 250 260 270 280 290 300 370 380 390 400 410 420 pF1KE2 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL 310 320 330 340 350 360 430 440 450 460 pF1KE2 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL ::::::::::::::::::::::::::::::::::::::::::::: XP_024 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL 370 380 390 400 410 >>XP_024306276 (OMIM: 606724) MAP kinase-interacting ser (412 aa) initn: 1794 init1: 1794 opt: 1794 Z-score: 823.1 bits: 161.4 E(91964): 4.5e-39 Smith-Waterman score: 2682; 90.9% identity (90.9% similar) in 453 aa overlap (13-465:1-412) 10 20 30 40 50 60 pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY :::::::::::::::::::::::::::::::::::::::::::::::: XP_024 MGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY 10 20 30 40 70 80 90 100 110 120 pF1KE2 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE2 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS :::::::::::::::::::::::::::::::::::::::::::: XP_024 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTK---------------- 110 120 130 140 150 190 200 210 220 230 240 pF1KE2 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK ::::::::::::::::::::::::::::::::::: XP_024 -------------------------GIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK 160 170 180 250 260 270 280 290 300 pF1KE2 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP 190 200 210 220 230 240 310 320 330 340 350 360 pF1KE2 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK 250 260 270 280 290 300 370 380 390 400 410 420 pF1KE2 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL 310 320 330 340 350 360 430 440 450 460 pF1KE2 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL ::::::::::::::::::::::::::::::::::::::::::::: XP_024 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL 370 380 390 400 410 465 residues in 1 query sequences 65089639 residues in 91964 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Oct 2 18:31:13 2018 done: Tue Oct 2 18:31:14 2018 Total Scan time: 4.670 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]