FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2730, 219 aa 1>>>pF1KE2730 219 - 219 aa - 219 aa Library: /omim/omim.rfq.tfa 64704883 residues in 91410 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9976+/-0.000373; mu= 15.1136+/- 0.023 mean_var=56.7742+/-11.636, 0's: 0 Z-trim(112.0): 23 B-trim: 568 in 1/49 Lambda= 0.170215 statistics sampled from 21557 (21570) to 21557 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.236), width: 16 Scan time: 2.580 The best scores are: opt bits E(91410) XP_024305807 (OMIM: 611541) sorting nexin-27 isofo ( 342) 1524 382.5 5e-106 XP_005245568 (OMIM: 611541) sorting nexin-27 isofo ( 342) 1524 382.5 5e-106 XP_016857906 (OMIM: 611541) sorting nexin-27 isofo ( 407) 1524 382.5 5.8e-106 NP_112180 (OMIM: 611541) sorting nexin-27 isoform ( 528) 1524 382.6 7.2e-106 XP_024305806 (OMIM: 611541) sorting nexin-27 isofo ( 355) 1510 379.1 5.6e-105 XP_011508327 (OMIM: 611541) sorting nexin-27 isofo ( 420) 1510 379.1 6.4e-105 XP_005245567 (OMIM: 611541) sorting nexin-27 isofo ( 438) 1510 379.1 6.7e-105 XP_011508326 (OMIM: 611541) sorting nexin-27 isofo ( 440) 1510 379.1 6.7e-105 NP_001317652 (OMIM: 611541) sorting nexin-27 isofo ( 541) 1510 379.1 8e-105 XP_011508328 (OMIM: 611541) sorting nexin-27 isofo ( 419) 491 128.9 1.4e-29 >>XP_024305807 (OMIM: 611541) sorting nexin-27 isoform X (342 aa) initn: 1524 init1: 1524 opt: 1524 Z-score: 2025.1 bits: 382.5 E(91410): 5e-106 Smith-Waterman score: 1524; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:124-342) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: XP_024 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 100 110 120 130 140 150 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS 160 170 180 190 200 210 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE 220 230 240 250 260 270 160 170 180 190 200 210 pF1KE2 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC 280 290 300 310 320 330 pF1KE2 ELKWRKEEY ::::::::: XP_024 ELKWRKEEY 340 >>XP_005245568 (OMIM: 611541) sorting nexin-27 isoform X (342 aa) initn: 1524 init1: 1524 opt: 1524 Z-score: 2025.1 bits: 382.5 E(91410): 5e-106 Smith-Waterman score: 1524; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:124-342) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: XP_005 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 100 110 120 130 140 150 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS 160 170 180 190 200 210 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE 220 230 240 250 260 270 160 170 180 190 200 210 pF1KE2 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC 280 290 300 310 320 330 pF1KE2 ELKWRKEEY ::::::::: XP_005 ELKWRKEEY 340 >>XP_016857906 (OMIM: 611541) sorting nexin-27 isoform X (407 aa) initn: 1524 init1: 1524 opt: 1524 Z-score: 2023.9 bits: 382.5 E(91410): 5.8e-106 Smith-Waterman score: 1524; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:189-407) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: XP_016 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 160 170 180 190 200 210 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS 220 230 240 250 260 270 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE 280 290 300 310 320 330 160 170 180 190 200 210 pF1KE2 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC 340 350 360 370 380 390 pF1KE2 ELKWRKEEY ::::::::: XP_016 ELKWRKEEY 400 >>NP_112180 (OMIM: 611541) sorting nexin-27 isoform 2 [H (528 aa) initn: 1524 init1: 1524 opt: 1524 Z-score: 2022.2 bits: 382.6 E(91410): 7.2e-106 Smith-Waterman score: 1524; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:310-528) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: NP_112 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 280 290 300 310 320 330 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS 340 350 360 370 380 390 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE 400 410 420 430 440 450 160 170 180 190 200 210 pF1KE2 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC 460 470 480 490 500 510 pF1KE2 ELKWRKEEY ::::::::: NP_112 ELKWRKEEY 520 >>XP_024305806 (OMIM: 611541) sorting nexin-27 isoform X (355 aa) initn: 1510 init1: 1510 opt: 1510 Z-score: 2006.3 bits: 379.1 E(91410): 5.6e-105 Smith-Waterman score: 1510; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:124-340) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: XP_024 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 100 110 120 130 140 150 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS 160 170 180 190 200 210 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE 220 230 240 250 260 270 160 170 180 190 200 210 pF1KE2 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC 280 290 300 310 320 330 pF1KE2 ELKWRKEEY ::::::: XP_024 ELKWRKENIFQMARSQQRDVAT 340 350 >>XP_011508327 (OMIM: 611541) sorting nexin-27 isoform X (420 aa) initn: 1510 init1: 1510 opt: 1510 Z-score: 2005.2 bits: 379.1 E(91410): 6.4e-105 Smith-Waterman score: 1510; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:189-405) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: XP_011 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 160 170 180 190 200 210 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS 220 230 240 250 260 270 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE 280 290 300 310 320 330 160 170 180 190 200 210 pF1KE2 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC 340 350 360 370 380 390 pF1KE2 ELKWRKEEY ::::::: XP_011 ELKWRKENIFQMARSQQRDVAT 400 410 420 >>XP_005245567 (OMIM: 611541) sorting nexin-27 isoform X (438 aa) initn: 1510 init1: 1510 opt: 1510 Z-score: 2004.9 bits: 379.1 E(91410): 6.7e-105 Smith-Waterman score: 1510; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:207-423) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: XP_005 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 180 190 200 210 220 230 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS 240 250 260 270 280 290 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE 300 310 320 330 340 350 160 170 180 190 200 210 pF1KE2 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC 360 370 380 390 400 410 pF1KE2 ELKWRKEEY ::::::: XP_005 ELKWRKENIFQMARSQQRDVAT 420 430 >>XP_011508326 (OMIM: 611541) sorting nexin-27 isoform X (440 aa) initn: 1510 init1: 1510 opt: 1510 Z-score: 2004.8 bits: 379.1 E(91410): 6.7e-105 Smith-Waterman score: 1510; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:209-425) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: XP_011 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 180 190 200 210 220 230 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS 240 250 260 270 280 290 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE 300 310 320 330 340 350 160 170 180 190 200 210 pF1KE2 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC 360 370 380 390 400 410 pF1KE2 ELKWRKEEY ::::::: XP_011 ELKWRKENIFQMARSQQRDVAT 420 430 440 >>NP_001317652 (OMIM: 611541) sorting nexin-27 isoform 1 (541 aa) initn: 1510 init1: 1510 opt: 1510 Z-score: 2003.5 bits: 379.1 E(91410): 8e-105 Smith-Waterman score: 1510; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:310-526) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: NP_001 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 280 290 300 310 320 330 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS 340 350 360 370 380 390 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE 400 410 420 430 440 450 160 170 180 190 200 210 pF1KE2 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFC 460 470 480 490 500 510 pF1KE2 ELKWRKEEY ::::::: NP_001 ELKWRKENIFQMARSQQRDVAT 520 530 540 >>XP_011508328 (OMIM: 611541) sorting nexin-27 isoform X (419 aa) initn: 491 init1: 491 opt: 491 Z-score: 652.8 bits: 128.9 E(91410): 1.4e-29 Smith-Waterman score: 491; 100.0% identity (100.0% similar) in 74 aa overlap (1-74:310-383) 10 20 30 pF1KE2 MDSTTVNYFALFEVISHSFVRKLAPNEFPH :::::::::::::::::::::::::::::: XP_011 ALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPH 280 290 300 310 320 330 40 50 60 70 80 90 pF1KE2 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS :::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQIPAASLHFPLLKMRHQ 340 350 360 370 380 390 100 110 120 130 140 150 pF1KE2 YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEE XP_011 LSFLLHSYHIPIPFSSLPSP 400 410 219 residues in 1 query sequences 64704883 residues in 91410 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Jul 14 21:19:13 2018 done: Sat Jul 14 21:19:13 2018 Total Scan time: 2.580 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]