FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2752, 1162 aa
1>>>pF1KE2752 1162 - 1162 aa - 1162 aa
Library: /omim/omim.rfq.tfa
64236559 residues in 92054 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4936+/-0.000355; mu= 8.4518+/- 0.022
mean_var=185.9259+/-37.931, 0's: 0 Z-trim(118.6): 249 B-trim: 33 in 1/56
Lambda= 0.094060
statistics sampled from 32651 (32905) to 32651 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.357), width: 16
Scan time: 8.400
The best scores are: opt bits E(92054)
XP_016858044 (OMIM: 604718) transcription terminat (1162) 7700 1058.3 0
NP_003585 (OMIM: 604718) transcription termination (1162) 7700 1058.3 0
XP_005271334 (OMIM: 604718) transcription terminat (1161) 7683 1056.0 0
XP_011540605 (OMIM: 604718) transcription terminat (1169) 7676 1055.0 0
XP_016858042 (OMIM: 604718) transcription terminat (1183) 4833 669.2 4.4e-191
XP_016858043 (OMIM: 604718) transcription terminat (1182) 4816 666.9 2.2e-190
XP_016858039 (OMIM: 604718) transcription terminat (1190) 4809 666.0 4.2e-190
XP_016858040 (OMIM: 604718) transcription terminat (1190) 4809 666.0 4.2e-190
XP_016858041 (OMIM: 604718) transcription terminat (1189) 4792 663.7 2.1e-189
NP_001305863 (OMIM: 603257) helicase-like transcri (1008) 430 71.7 2.8e-11
XP_016862568 (OMIM: 603257) helicase-like transcri (1008) 430 71.7 2.8e-11
NP_001305864 (OMIM: 603257) helicase-like transcri (1009) 430 71.7 2.8e-11
NP_003062 (OMIM: 603257) helicase-like transcripti (1009) 430 71.7 2.8e-11
NP_620636 (OMIM: 603257) helicase-like transcripti (1009) 430 71.7 2.8e-11
XP_016862567 (OMIM: 603257) helicase-like transcri (1012) 430 71.7 2.8e-11
XP_011511395 (OMIM: 603257) helicase-like transcri (1012) 430 71.7 2.8e-11
XP_011511394 (OMIM: 603257) helicase-like transcri (1013) 430 71.7 2.8e-11
XP_011511393 (OMIM: 603257) helicase-like transcri (1013) 430 71.7 2.8e-11
NP_001192192 (OMIM: 604289,605027) DNA repair and ( 726) 381 65.0 2.2e-09
NP_036547 (OMIM: 604289,605027) DNA repair and rec ( 910) 381 65.0 2.6e-09
XP_011540602 (OMIM: 114480,603615,605027) DNA repa ( 489) 359 61.9 1.2e-08
XP_011540601 (OMIM: 114480,603615,605027) DNA repa ( 489) 359 61.9 1.2e-08
NP_001357695 (OMIM: 114480,603615,605027) DNA repa ( 567) 359 61.9 1.4e-08
NP_003570 (OMIM: 114480,603615,605027) DNA repair ( 747) 359 62.0 1.7e-08
NP_001136020 (OMIM: 114480,603615,605027) DNA repa ( 747) 359 62.0 1.7e-08
XP_011519988 (OMIM: 610169) chromatin-remodeling A ( 906) 358 61.9 2.2e-08
NP_060023 (OMIM: 610169) chromatin-remodeling ATPa (1556) 358 62.1 3.4e-08
NP_001357257 (OMIM: 608048) E3 ubiquitin-protein l (1202) 352 61.2 4.9e-08
XP_016866185 (OMIM: 608048) E3 ubiquitin-protein l (1263) 352 61.2 5.1e-08
XP_024302162 (OMIM: 608048) E3 ubiquitin-protein l (1263) 352 61.2 5.1e-08
XP_024302161 (OMIM: 608048) E3 ubiquitin-protein l (1430) 352 61.2 5.7e-08
XP_006715506 (OMIM: 608048) E3 ubiquitin-protein l (1507) 352 61.2 5.9e-08
NP_775105 (OMIM: 608048) E3 ubiquitin-protein liga (1659) 352 61.3 6.4e-08
XP_011534021 (OMIM: 608048) E3 ubiquitin-protein l (1677) 352 61.3 6.4e-08
NP_001036148 (OMIM: 608048) E3 ubiquitin-protein l (1683) 352 61.3 6.5e-08
NP_001357256 (OMIM: 608048) E3 ubiquitin-protein l (1683) 352 61.3 6.5e-08
XP_016866182 (OMIM: 608048) E3 ubiquitin-protein l (1690) 352 61.3 6.5e-08
XP_006715502 (OMIM: 608048) E3 ubiquitin-protein l (1707) 352 61.3 6.5e-08
XP_016866180 (OMIM: 608048) E3 ubiquitin-protein l (1744) 352 61.3 6.6e-08
XP_016866181 (OMIM: 608048) E3 ubiquitin-protein l (1744) 352 61.3 6.6e-08
NP_006653 (OMIM: 136140,611421) helicase SRCAP [Ho (3230) 353 61.6 9.9e-08
XP_016872369 (OMIM: 605191) TATA-binding protein-a (1519) 343 60.0 1.4e-07
XP_016872370 (OMIM: 605191) TATA-binding protein-a (1519) 343 60.0 1.4e-07
XP_016872368 (OMIM: 605191) TATA-binding protein-a (1519) 343 60.0 1.4e-07
XP_016872367 (OMIM: 605191) TATA-binding protein-a (1646) 343 60.0 1.5e-07
XP_011538630 (OMIM: 605191) TATA-binding protein-a (1693) 343 60.1 1.5e-07
XP_011538629 (OMIM: 605191) TATA-binding protein-a (1725) 343 60.1 1.5e-07
XP_016872366 (OMIM: 605191) TATA-binding protein-a (1800) 343 60.1 1.6e-07
XP_011538628 (OMIM: 605191) TATA-binding protein-a (1812) 343 60.1 1.6e-07
NP_003963 (OMIM: 605191) TATA-binding protein-asso (1849) 343 60.1 1.6e-07
>>XP_016858044 (OMIM: 604718) transcription termination (1162 aa)
initn: 7700 init1: 7700 opt: 7700 Z-score: 5654.9 bits: 1058.3 E(92054): 0
Smith-Waterman score: 7700; 100.0% identity (100.0% similar) in 1162 aa overlap (1-1162:1-1162)
10 20 30 40 50 60
pF1KE2 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 SELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 MLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV
1090 1100 1110 1120 1130 1140
1150 1160
pF1KE2 LSGSGESVTKLTLADLRVLFGI
::::::::::::::::::::::
XP_016 LSGSGESVTKLTLADLRVLFGI
1150 1160
>>NP_003585 (OMIM: 604718) transcription termination fac (1162 aa)
initn: 7700 init1: 7700 opt: 7700 Z-score: 5654.9 bits: 1058.3 E(92054): 0
Smith-Waterman score: 7700; 100.0% identity (100.0% similar) in 1162 aa overlap (1-1162:1-1162)
10 20 30 40 50 60
pF1KE2 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 SELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 MLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV
1090 1100 1110 1120 1130 1140
1150 1160
pF1KE2 LSGSGESVTKLTLADLRVLFGI
::::::::::::::::::::::
NP_003 LSGSGESVTKLTLADLRVLFGI
1150 1160
>>XP_005271334 (OMIM: 604718) transcription termination (1161 aa)
initn: 4025 init1: 4025 opt: 7683 Z-score: 5642.4 bits: 1056.0 E(92054): 0
Smith-Waterman score: 7683; 99.9% identity (99.9% similar) in 1162 aa overlap (1-1162:1-1161)
10 20 30 40 50 60
pF1KE2 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_005 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGIL-DDMGL
550 560 570 580 590
610 620 630 640 650 660
pF1KE2 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE2 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE2 GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE2 KFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKF
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE2 QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE2 RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 SELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTN
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE2 MLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGG
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE2 NHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV
1080 1090 1100 1110 1120 1130
1150 1160
pF1KE2 LSGSGESVTKLTLADLRVLFGI
::::::::::::::::::::::
XP_005 LSGSGESVTKLTLADLRVLFGI
1140 1150 1160
>>XP_011540605 (OMIM: 604718) transcription termination (1169 aa)
initn: 4182 init1: 4182 opt: 7676 Z-score: 5637.3 bits: 1055.0 E(92054): 0
Smith-Waterman score: 7676; 99.4% identity (99.4% similar) in 1169 aa overlap (1-1162:1-1169)
10 20 30 40 50 60
pF1KE2 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRG-------HTNQDHVH
::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGNTYLYAGHTNQDHVH
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 AVWKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVWKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 LADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 HHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIP
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 GANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNL
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 LDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLV
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 ILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVAL
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 EFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEE
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 QLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSV
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 IVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGV
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 GLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKK
1090 1100 1110 1120 1130 1140
1140 1150 1160
pF1KE2 KDLAKQVLSGSGESVTKLTLADLRVLFGI
:::::::::::::::::::::::::::::
XP_011 KDLAKQVLSGSGESVTKLTLADLRVLFGI
1150 1160
>>XP_016858042 (OMIM: 604718) transcription termination (1183 aa)
initn: 4833 init1: 4833 opt: 4833 Z-score: 3552.2 bits: 669.2 E(92054): 4.4e-191
Smith-Waterman score: 7648; 98.2% identity (98.2% similar) in 1183 aa overlap (1-1162:1-1183)
10 20 30 40 50 60
pF1KE2 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
670 680 690 700 710 720
730 740 750
pF1KE2 ---------------------GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQAC
:::::::::::::::::::::::::::::::::::::::
XP_016 TLSIHYGSGAVSSRAARFPLQGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQAC
730 740 750 760 770 780
760 770 780 790 800 810
pF1KE2 ARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLR
790 800 810 820 830 840
820 830 840 850 860 870
pF1KE2 RTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQ
850 860 870 880 890 900
880 890 900 910 920 930
pF1KE2 SGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDP
910 920 930 940 950 960
940 950 960 970 980 990
pF1KE2 MELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAE
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KE2 LEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSR
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KE2 GPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCE
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160
pF1KE2 GTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
:::::::::::::::::::::::::::::::::::::::::::
XP_016 GTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
1150 1160 1170 1180
>>XP_016858043 (OMIM: 604718) transcription termination (1182 aa)
initn: 6886 init1: 4025 opt: 4816 Z-score: 3539.7 bits: 666.9 E(92054): 2.2e-190
Smith-Waterman score: 7631; 98.1% identity (98.1% similar) in 1183 aa overlap (1-1162:1-1182)
10 20 30 40 50 60
pF1KE2 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGIL-DDMGL
550 560 570 580 590
610 620 630 640 650 660
pF1KE2 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE2 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
660 670 680 690 700 710
730 740 750
pF1KE2 ---------------------GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQAC
:::::::::::::::::::::::::::::::::::::::
XP_016 TLSIHYGSGAVSSRAARFPLQGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQAC
720 730 740 750 760 770
760 770 780 790 800 810
pF1KE2 ARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLR
780 790 800 810 820 830
820 830 840 850 860 870
pF1KE2 RTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQ
840 850 860 870 880 890
880 890 900 910 920 930
pF1KE2 SGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDP
900 910 920 930 940 950
940 950 960 970 980 990
pF1KE2 MELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAE
960 970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KE2 LEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSR
1020 1030 1040 1050 1060 1070
1060 1070 1080 1090 1100 1110
pF1KE2 GPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCE
1080 1090 1100 1110 1120 1130
1120 1130 1140 1150 1160
pF1KE2 GTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
:::::::::::::::::::::::::::::::::::::::::::
XP_016 GTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
1140 1150 1160 1170 1180
>>XP_016858039 (OMIM: 604718) transcription termination (1190 aa)
initn: 6407 init1: 3546 opt: 4809 Z-score: 3534.5 bits: 666.0 E(92054): 4.2e-190
Smith-Waterman score: 7624; 97.6% identity (97.6% similar) in 1190 aa overlap (1-1162:1-1190)
10 20 30 40 50 60
pF1KE2 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRG-------HTNQDHVH
::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGNTYLYAGHTNQDHVH
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 AVWKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVWKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 LADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 HHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIP
670 680 690 700 710 720
720 730 740 750
pF1KE2 GANLNVE---------------------GTSTPLLRIAWARIILDEAHNVKNPRVQTSIA
::::::: ::::::::::::::::::::::::::::::::
XP_016 GANLNVETLSIHYGSGAVSSRAARFPLQGTSTPLLRIAWARIILDEAHNVKNPRVQTSIA
730 740 750 760 770 780
760 770 780 790 800 810
pF1KE2 VCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSIL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KE2 TKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKR
850 860 870 880 890 900
880 890 900 910 920 930
pF1KE2 HESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSL
910 920 930 940 950 960
940 950 960 970 980 990
pF1KE2 LKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTK
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KE2 ISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLV
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KE2 EAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVV
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160
pF1KE2 IHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
1150 1160 1170 1180 1190
>>XP_016858040 (OMIM: 604718) transcription termination (1190 aa)
initn: 6407 init1: 3546 opt: 4809 Z-score: 3534.5 bits: 666.0 E(92054): 4.2e-190
Smith-Waterman score: 7624; 97.6% identity (97.6% similar) in 1190 aa overlap (1-1162:1-1190)
10 20 30 40 50 60
pF1KE2 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRG-------HTNQDHVH
::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGNTYLYAGHTNQDHVH
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 AVWKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVWKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 LADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 HHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIP
670 680 690 700 710 720
720 730 740 750
pF1KE2 GANLNVE---------------------GTSTPLLRIAWARIILDEAHNVKNPRVQTSIA
::::::: ::::::::::::::::::::::::::::::::
XP_016 GANLNVETLSIHYGSGAVSSRAARFPLQGTSTPLLRIAWARIILDEAHNVKNPRVQTSIA
730 740 750 760 770 780
760 770 780 790 800 810
pF1KE2 VCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSIL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KE2 TKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKR
850 860 870 880 890 900
880 890 900 910 920 930
pF1KE2 HESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSL
910 920 930 940 950 960
940 950 960 970 980 990
pF1KE2 LKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTK
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KE2 ISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLV
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KE2 EAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVV
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160
pF1KE2 IHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
1150 1160 1170 1180 1190
>>XP_016858041 (OMIM: 604718) transcription termination (1189 aa)
initn: 6407 init1: 3546 opt: 4792 Z-score: 3522.1 bits: 663.7 E(92054): 2.1e-189
Smith-Waterman score: 7607; 97.6% identity (97.6% similar) in 1190 aa overlap (1-1162:1-1189)
10 20 30 40 50 60
pF1KE2 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRG-------HTNQDHVH
::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGNTYLYAGHTNQDHVH
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 AVWKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVWKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 LADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLI
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 L-DDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLI
610 620 630 640 650
660 670 680 690 700 710
pF1KE2 HHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIP
660 670 680 690 700 710
720 730 740 750
pF1KE2 GANLNVE---------------------GTSTPLLRIAWARIILDEAHNVKNPRVQTSIA
::::::: ::::::::::::::::::::::::::::::::
XP_016 GANLNVETLSIHYGSGAVSSRAARFPLQGTSTPLLRIAWARIILDEAHNVKNPRVQTSIA
720 730 740 750 760 770
760 770 780 790 800 810
pF1KE2 VCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSIL
780 790 800 810 820 830
820 830 840 850 860 870
pF1KE2 TKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKR
840 850 860 870 880 890
880 890 900 910 920 930
pF1KE2 HESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSL
900 910 920 930 940 950
940 950 960 970 980 990
pF1KE2 LKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTK
960 970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KE2 ISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLV
1020 1030 1040 1050 1060 1070
1060 1070 1080 1090 1100 1110
pF1KE2 EAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVV
1080 1090 1100 1110 1120 1130
1120 1130 1140 1150 1160
pF1KE2 IHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
1140 1150 1160 1170 1180
>>NP_001305863 (OMIM: 603257) helicase-like transcriptio (1008 aa)
initn: 1061 init1: 291 opt: 430 Z-score: 324.1 bits: 71.7 E(92054): 2.8e-11
Smith-Waterman score: 852; 32.0% identity (60.3% similar) in 590 aa overlap (608-1137:442-980)
580 590 600 610 620 630
pF1KE2 LAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSC
:: . . .:: :. . :. .: :
NP_001 MKGKLKNVQSETKGRAKGSSKVIEDVAFACALTSSVPTTKKKMLKKGACAVEGSKKTD-V
420 430 440 450 460 470
640 650 660 670 680 690
pF1KE2 DFTSHGTLIICPASLIHHWKNEVEKRVNSN-KLRVYLYHGPNRDSRARVLSTYDIVITTY
. . :::::: :.. .: .. ....:. .: :.:.::.: . .:: :::.:::
NP_001 EERPRTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYGPDRIREPALLSKQDIVLTTY
480 490 500 510 520 530
700 710 720 730 740 750
pF1KE2 SLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKL
...... : .: : :: : : :.::::.: ..:: .: . :: :
NP_001 NILTHDYGT--------------KGDS-PLHSIRWLRVILDEGHAIRNPNAQQTKAVLDL
540 550 560 570
760 770 780 790 800 810
pF1KE2 QACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDN----GSKKGGERLSIL
.. ::..:::::::.: :..:::.::. .:: . . :. .. :.. : .::. :
NP_001 ESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWHRTIQRPVTMGDEGGLRRLQSL
580 590 600 610 620 630
820 830 840 850 860 870
pF1KE2 TKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKR
:.. ::::: . :.:.. ::.:: ..:. ::..:. .: :: .
NP_001 IKNITLRRTKTS-KIKGKPVLELPERKVFIQHITLSDEERKIY-----------QSV--K
640 650 660 670 680
880 890 900 910 920 930
pF1KE2 HESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSL
.:.:.. :: :. :. .. :: .:. :::::: ::: :
NP_001 NEGRATI-GRYFNE---------GTVLAHY---AD--------VLGLLLRLRQICCHTYL
690 700 710 720
940 950 960
pF1KE2 LKSALD---------PMELKGE-----GLVLSL--EEQ----LSALTL------------
: .:.. : ::. . :.:: .:. :..::.
NP_001 LTNAVSSNGPSGNDTPEELRKKLIRKMKLILSSGSDEECAICLDSLTVPVITHCAHVFCK
730 740 750 760 770 780
970 980 990
pF1KE2 ----SELRDSEPSSTVSL-NGTFFKMELFEGMRE----------------STKISSLLAE
. ... .: . : . . . .:.: : :.::..:.
NP_001 PCICQVIQNEQPHAKCPLCRNDIHEDNLLECPPEELARDSEKKSDMEWTSSSKINALMHA
790 800 810 820 830 840
1000 1010 1020 1030 1040 1050
pF1KE2 LEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSR
: ..... . ::..:::.:..:... . :: :.... .:::. :.:.. .. :....
NP_001 LTDLRKKNPNIKSLVVSQFTTFLSLIEIPLKASGFVFTRLDGSMAQKKRVESIQCFQNTE
850 860 870 880 890 900
1060 1070 1080 1090 1100 1110
pF1KE2 G--PQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFV
. : .::.:: ::::::::......::.: :::. ::: :: .:.::...:.: .:.
NP_001 AGSPTIMLLSLKAGGVGLNLSAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFI
910 920 930 940 950 960
1120 1130 1140 1150 1160
pF1KE2 CEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI
. .:::..:..:.::..::
NP_001 VKDSVEENMLKIQNKKRELAAGAFGTKKPNADEMKQAKINEIRTLIDL
970 980 990 1000
1162 residues in 1 query sequences
64236559 residues in 92054 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Aug 1 17:02:57 2019 done: Thu Aug 1 17:02:58 2019
Total Scan time: 8.400 Total Display time: 0.320
Function used was FASTA [36.3.4 Apr, 2011]