FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3023, 138 aa 1>>>pF1KE3023 138 - 138 aa - 138 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1515+/-0.000772; mu= 12.5517+/- 0.047 mean_var=69.3103+/-14.017, 0's: 0 Z-trim(108.6): 18 B-trim: 52 in 1/49 Lambda= 0.154055 statistics sampled from 10427 (10439) to 10427 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.312), width: 16 Scan time: 0.690 The best scores are: opt bits E(33420) CCDS880.1 TSHB gene_id:7252|Hs109|chr1 ( 138) 977 225.4 8.7e-60 CCDS7868.1 FSHB gene_id:2488|Hs109|chr11 ( 129) 378 92.3 9.8e-20 CCDS12748.1 LHB gene_id:3972|Hs109|chr19 ( 141) 355 87.2 3.6e-18 CCDS12751.2 CGB1 gene_id:114335|Hs109|chr19 ( 155) 337 83.2 6.3e-17 CCDS12750.2 CGB2 gene_id:114336|Hs109|chr19 ( 163) 337 83.2 6.6e-17 CCDS12753.1 CGB8 gene_id:94115|Hs109|chr19 ( 165) 337 83.3 6.6e-17 CCDS12749.1 CGB3 gene_id:1082|Hs109|chr19 ( 165) 337 83.3 6.6e-17 CCDS12752.1 CGB5 gene_id:93659|Hs109|chr19 ( 165) 337 83.3 6.6e-17 CCDS33071.1 CGB7 gene_id:94027|Hs109|chr19 ( 165) 336 83.0 7.7e-17 >>CCDS880.1 TSHB gene_id:7252|Hs109|chr1 (138 aa) initn: 977 init1: 977 opt: 977 Z-score: 1187.0 bits: 225.4 E(33420): 8.7e-60 Smith-Waterman score: 977; 99.3% identity (100.0% similar) in 138 aa overlap (1-138:1-138) 10 20 30 40 50 60 pF1KE3 MTALFLMSMLFGLACGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: CCDS88 MTALFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS88 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI 70 80 90 100 110 120 130 pF1KE3 KTNYCTKPQKSYLVGFSV :::::::::::::::::: CCDS88 KTNYCTKPQKSYLVGFSV 130 >>CCDS7868.1 FSHB gene_id:2488|Hs109|chr11 (129 aa) initn: 402 init1: 224 opt: 378 Z-score: 468.0 bits: 92.3 E(33420): 9.8e-20 Smith-Waterman score: 378; 40.2% identity (72.1% similar) in 122 aa overlap (7-126:4-123) 10 20 30 40 50 pF1KE3 MTALFLMSMLFGLACGQAM--SFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDING ....: . : .:. . : :. :. ::..:: .:..:::: :::::.:::. CCDS78 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVY 10 20 30 40 50 60 70 80 90 100 110 pF1KE3 KLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHE : : : .::.....:.::..::: :. ..:::: .:.::::..: .:: . CCDS78 KD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVR 60 70 80 90 100 110 120 130 pF1KE3 AIKTNYCTKPQKSYLVGFSV .. .::. CCDS78 GLGPSYCSFGEMKE 120 >>CCDS12748.1 LHB gene_id:3972|Hs109|chr19 (141 aa) initn: 369 init1: 225 opt: 355 Z-score: 439.8 bits: 87.2 E(33420): 3.6e-18 Smith-Waterman score: 355; 41.7% identity (61.4% similar) in 132 aa overlap (4-134:10-139) 10 20 30 40 50 pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYCMT :.:.:: . : . . .: : . . .:.. : :.:.::::::::: : CCDS12 MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE3 RDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYS . :: : : :::::: ......:::: : : :.::::::.:: : . : CCDS12 MMRVLQAVLP--PLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTS 70 80 90 100 110 120 130 pF1KE3 DCIHEAIKTNYCTKPQKSYLVGFSV :: . : .:: : :. CCDS12 DCGGPKDHPLTCDHPQLSGLLFL 120 130 140 >>CCDS12751.2 CGB1 gene_id:114335|Hs109|chr19 (155 aa) initn: 321 init1: 197 opt: 337 Z-score: 417.6 bits: 83.2 E(33420): 6.3e-17 Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:8-132) 10 20 30 40 50 pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC--MT :.:.:: : . . : : . :. .:.. : :.:.::::::::: :: CCDS12 MSKRLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE3 RDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYS : ..: :: :: : ::.::: ......:::: : : :: :::::.:. : . . CCDS12 RVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTT 70 80 90 100 110 120 130 pF1KE3 DCIHEAIKTNYCTKPQKSYLVGFSV :: . : :. CCDS12 DCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGP 120 130 140 150 >>CCDS12750.2 CGB2 gene_id:114336|Hs109|chr19 (163 aa) initn: 321 init1: 197 opt: 337 Z-score: 417.3 bits: 83.2 E(33420): 6.6e-17 Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:8-132) 10 20 30 40 50 pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC--MT :.:.:: : . . : : . :. .:.. : :.:.::::::::: :: CCDS12 MSKGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE3 RDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYS : ..: :: :: : ::.::: ......:::: : : :: :::::.:. : . . CCDS12 RVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTT 70 80 90 100 110 120 130 pF1KE3 DCIHEAIKTNYCTKPQKSYLVGFSV :: . : :. CCDS12 DCGGPKDHPLTCDDPRFQASSSSKAPPPSLPSPSRLPGPSDTPILPQ 120 130 140 150 160 >>CCDS12753.1 CGB8 gene_id:94115|Hs109|chr19 (165 aa) initn: 321 init1: 197 opt: 337 Z-score: 417.2 bits: 83.3 E(33420): 6.6e-17 Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:10-134) 10 20 30 40 50 pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC-- :.:.:: : . . : : . :. .:.. : :.:.::::::::: CCDS12 MEMFQGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE3 MTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTD ::: ..: :: :: : ::.::: ......:::: : : :: :::::.:. : . CCDS12 MTRVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRS 70 80 90 100 110 120 130 pF1KE3 YSDCIHEAIKTNYCTKPQKSYLVGFSV .:: . : :. CCDS12 TTDCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ 120 130 140 150 160 >>CCDS12749.1 CGB3 gene_id:1082|Hs109|chr19 (165 aa) initn: 321 init1: 197 opt: 337 Z-score: 417.2 bits: 83.3 E(33420): 6.6e-17 Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:10-134) 10 20 30 40 50 pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC-- :.:.:: : . . : : . :. .:.. : :.:.::::::::: CCDS12 MEMFQGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE3 MTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTD ::: ..: :: :: : ::.::: ......:::: : : :: :::::.:. : . CCDS12 MTRVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRS 70 80 90 100 110 120 130 pF1KE3 YSDCIHEAIKTNYCTKPQKSYLVGFSV .:: . : :. CCDS12 TTDCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ 120 130 140 150 160 >>CCDS12752.1 CGB5 gene_id:93659|Hs109|chr19 (165 aa) initn: 321 init1: 197 opt: 337 Z-score: 417.2 bits: 83.3 E(33420): 6.6e-17 Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:10-134) 10 20 30 40 50 pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC-- :.:.:: : . . : : . :. .:.. : :.:.::::::::: CCDS12 MEMFQGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE3 MTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTD ::: ..: :: :: : ::.::: ......:::: : : :: :::::.:. : . CCDS12 MTRVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRS 70 80 90 100 110 120 130 pF1KE3 YSDCIHEAIKTNYCTKPQKSYLVGFSV .:: . : :. CCDS12 TTDCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ 120 130 140 150 160 >>CCDS33071.1 CGB7 gene_id:94027|Hs109|chr19 (165 aa) initn: 321 init1: 197 opt: 336 Z-score: 416.0 bits: 83.0 E(33420): 7.7e-17 Smith-Waterman score: 336; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:10-134) 10 20 30 40 50 pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC-- :.:.:: : . . : : . :. .:.. : :.:.::::::::: CCDS33 MEMFQGLLLLLLLSMGGTWASREMLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE3 MTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTD ::: ..: :: :: : ::.::: ......:::: : : :: :::::.:. : . CCDS33 MTRVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRS 70 80 90 100 110 120 130 pF1KE3 YSDCIHEAIKTNYCTKPQKSYLVGFSV .:: . : :. CCDS33 TTDCGGPKDHPLTCDDPRFQASSSSKAPPPSLPSPSRLPGPSDTPILPQ 120 130 140 150 160 138 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Jun 20 10:38:23 2019 done: Thu Jun 20 10:38:23 2019 Total Scan time: 0.690 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]