FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3105, 259 aa 1>>>pF1KE3105 259 - 259 aa - 259 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0800+/-0.000676; mu= 16.8532+/- 0.041 mean_var=68.4231+/-13.533, 0's: 0 Z-trim(110.7): 54 B-trim: 11 in 1/51 Lambda= 0.155050 statistics sampled from 11913 (11967) to 11913 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.358), width: 16 Scan time: 1.100 The best scores are: opt bits E(33420) CCDS14.1 UBE2J2 gene_id:118424|Hs109|chr1 ( 259) 1751 399.9 9e-112 CCDS15.1 UBE2J2 gene_id:118424|Hs109|chr1 ( 275) 1456 334.0 6.9e-92 CCDS16.1 UBE2J2 gene_id:118424|Hs109|chr1 ( 207) 1397 320.7 5.2e-88 CCDS5021.1 UBE2J1 gene_id:51465|Hs109|chr6 ( 318) 454 109.9 2.3e-24 CCDS2282.1 UBE2E3 gene_id:10477|Hs109|chr2 ( 207) 270 68.6 4e-12 CCDS14580.1 UBE2A gene_id:7319|Hs109|chrX ( 152) 265 67.4 6.9e-12 CCDS4174.1 UBE2B gene_id:7320|Hs109|chr5 ( 152) 265 67.4 6.9e-12 CCDS2638.1 UBE2E1 gene_id:7324|Hs109|chr3 ( 193) 266 67.7 7.1e-12 CCDS2637.1 UBE2E2 gene_id:7325|Hs109|chr3 ( 201) 265 67.5 8.5e-12 CCDS56244.1 UBE2E1 gene_id:7324|Hs109|chr3 ( 160) 252 64.5 5.4e-11 CCDS5474.1 UBE2D4 gene_id:51619|Hs109|chr7 ( 147) 248 63.6 9.3e-11 >>CCDS14.1 UBE2J2 gene_id:118424|Hs109|chr1 (259 aa) initn: 1751 init1: 1751 opt: 1751 Z-score: 2120.3 bits: 399.9 E(33420): 9e-112 Smith-Waterman score: 1751; 100.0% identity (100.0% similar) in 259 aa overlap (1-259:1-259) 10 20 30 40 50 60 pF1KE3 MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 YHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 FMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDELSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDELSSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 PQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRHHGLLGGALANLFVIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANRHHGLLGGALANLFVIV 190 200 210 220 230 240 250 pF1KE3 GFAAFAYTVKYVLRSIAQE ::::::::::::::::::: CCDS14 GFAAFAYTVKYVLRSIAQE 250 >>CCDS15.1 UBE2J2 gene_id:118424|Hs109|chr1 (275 aa) initn: 1737 init1: 1456 opt: 1456 Z-score: 1763.3 bits: 334.0 E(33420): 6.9e-92 Smith-Waterman score: 1709; 94.2% identity (94.2% similar) in 275 aa overlap (1-259:1-275) 10 20 30 40 pF1KE3 MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEW---------------- :::::::::::::::::::::::::::::::::::::::::::: CCDS15 MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWFKRFSWLSLLSSWDYR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE3 HYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 HYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDT 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE3 WNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 WNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVV 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE3 EEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 EEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLLNGHAPGAVPNLAGLQQANR 190 200 210 220 230 240 230 240 250 pF1KE3 HHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE ::::::::::::::::::::::::::::::::::: CCDS15 HHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE 250 260 270 >>CCDS16.1 UBE2J2 gene_id:118424|Hs109|chr1 (207 aa) initn: 1397 init1: 1397 opt: 1397 Z-score: 1693.7 bits: 320.7 E(33420): 5.2e-88 Smith-Waterman score: 1397; 100.0% identity (100.0% similar) in 207 aa overlap (53-259:1-207) 30 40 50 60 70 80 pF1KE3 RIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMIT :::::::::::::::::::::::::::::: CCDS16 MTPYEGGYYHGKLIFPREFPFKPPSIYMIT 10 20 30 90 100 110 120 130 140 pF1KE3 PNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 PNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKRQL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE3 AVQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 AVQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGI 100 110 120 130 140 150 210 220 230 240 250 pF1KE3 QLLNGHAPGAVPNLAGLQQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 QLLNGHAPGAVPNLAGLQQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE 160 170 180 190 200 >>CCDS5021.1 UBE2J1 gene_id:51465|Hs109|chr6 (318 aa) initn: 416 init1: 416 opt: 454 Z-score: 551.1 bits: 109.9 E(33420): 2.3e-24 Smith-Waterman score: 454; 40.7% identity (73.3% similar) in 150 aa overlap (1-149:1-147) 10 20 30 40 50 60 pF1KE3 MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGY : . . ..: :..:: .. ..: ::. . :.:: .:..:::..:::: . ..:: CCDS50 METRYNLKSP--AVKRLMKEAAELK-DPTDHYHAQPLEDNLFEWHFTVRGPPDSDFDGGV 10 20 30 40 50 70 80 90 100 110 120 pF1KE3 YHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLS :::....: :.:.::::: ..: ::::. . ..::::. ::.::.:.::. : : .... CCDS50 YHGRIVLPPEYPMKPPSIILLTANGRFEVGKKICLSISGHHPETWQPSWSIRTALLAIIG 60 70 80 90 100 110 130 140 150 160 170 pF1KE3 FMVEKGP-TLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDELSS :: :: ..::.. . .: :: .: : CCDS50 FMPTKGEGAIGSLDYTPEERRALAKKSQDFCCEGCGSAMKDVLLPLKSGSDSSQADQEAK 120 130 140 150 160 170 >>CCDS2282.1 UBE2E3 gene_id:10477|Hs109|chr2 (207 aa) initn: 187 init1: 159 opt: 270 Z-score: 331.3 bits: 68.6 E(33420): 4e-12 Smith-Waterman score: 270; 32.0% identity (61.9% similar) in 147 aa overlap (1-140:51-191) 10 20 30 pF1KE3 MSSTSSKRAPTTATQRLKQDYLRIKKDPVP .:: .. . :.: .:.... .: :: : CCDS22 DADQRDPAAPEPEEQEERKPSATQQKKNTKLSSKTTAKLSTSA-KRIQKELAEITLDPPP 30 40 50 60 70 40 50 60 70 80 90 pF1KE3 YICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCN : : .:: ::. .. :: . :::: . . : ..:::::.. . : ..:: CCDS22 NCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRI--YHCN 80 90 100 110 120 130 100 110 120 130 140 pF1KE3 TR----LCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPT---LGSIETSDFTKRQLA .:: :. :.:.:: ..: .: .. :.... .:. .::: :. .:.: CCDS22 INSQGVICL---DILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEH 140 150 160 170 180 190 150 160 170 180 190 200 pF1KE3 VQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQ CCDS22 DRIARQWTKRYAT 200 >>CCDS14580.1 UBE2A gene_id:7319|Hs109|chrX (152 aa) initn: 243 init1: 192 opt: 265 Z-score: 327.1 bits: 67.4 E(33420): 6.9e-12 Smith-Waterman score: 265; 33.9% identity (65.3% similar) in 121 aa overlap (11-127:3-118) 10 20 30 40 50 60 pF1KE3 MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGY : : .:: .:. :...:: . . : .::. :. :. ::: ::.: : CCDS14 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGT 10 20 30 40 50 70 80 90 100 110 pF1KE3 YHGKLIFPREFPFKPPSIYMIT----PNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILT .. . : .:.: :::.. ... :: . .::.: . . :.:...::.::: CCDS14 FKLTIEFTEEYPNKPPTVRFVSKMFHPN--VYADGSICLDILQ---NRWSPTYDVSSILT 60 70 80 90 100 120 130 140 150 160 170 pF1KE3 GLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDE .. :.. : .: CCDS14 SIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC 110 120 130 140 150 >>CCDS4174.1 UBE2B gene_id:7320|Hs109|chr5 (152 aa) initn: 242 init1: 191 opt: 265 Z-score: 327.1 bits: 67.4 E(33420): 6.9e-12 Smith-Waterman score: 265; 34.7% identity (65.3% similar) in 121 aa overlap (11-127:3-118) 10 20 30 40 50 60 pF1KE3 MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGY : : .:: .:. :...:: . . : .::..:. :. ::: ::.: : CCDS41 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGT 10 20 30 40 50 70 80 90 100 110 pF1KE3 YHGKLIFPREFPFKPPSIY----MITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILT .. . : .:.: :::.. :. :: . .::.: . . :.:...::.::: CCDS41 FKLVIEFSEEYPNKPPTVRFLSKMFHPN--VYADGSICLDILQ---NRWSPTYDVSSILT 60 70 80 90 100 120 130 140 150 160 170 pF1KE3 GLLSFMVEKGPTLGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDE .. :.. : .: CCDS41 SIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS 110 120 130 140 150 >>CCDS2638.1 UBE2E1 gene_id:7324|Hs109|chr3 (193 aa) initn: 210 init1: 161 opt: 266 Z-score: 326.9 bits: 67.7 E(33420): 7.1e-12 Smith-Waterman score: 266; 31.3% identity (62.6% similar) in 147 aa overlap (1-140:36-177) 10 20 30 pF1KE3 MSSTSSKRAPTTATQRLKQDYLRIKKDPVP .: ..... .:...:.... : :: : CCDS26 SRASTSSSSSSSSNQQTEKETNTPKKKESKVSMSKNSKLLSTSAKRIQKELADITLDPPP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE3 YICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCN : : .:: ::. .. :: . :::: . . : :.:::::.. . : ..:: CCDS26 NCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRI--YHCN 70 80 90 100 110 120 100 110 120 130 140 pF1KE3 TR----LCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPT---LGSIETSDFTKRQLA .:: :. :.:.:: ..: .: .. :.... .:. .::: :. .:.: CCDS26 INSQGVICL---DILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEH 130 140 150 160 170 180 150 160 170 180 190 200 pF1KE3 VQSLAFNLKDKVFCELFPEVVEEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQ CCDS26 DRMARQWTKRYAT 190 >>CCDS2637.1 UBE2E2 gene_id:7325|Hs109|chr3 (201 aa) initn: 184 init1: 157 opt: 265 Z-score: 325.4 bits: 67.5 E(33420): 8.5e-12 Smith-Waterman score: 265; 33.1% identity (62.1% similar) in 145 aa overlap (5-140:46-185) 10 20 30 pF1KE3 MSSTSSKRAP--TTATQRLKQDYLRIKKDPVPYI ::: : .:...:.... .: :: : CCDS26 GGSSDGDQRESVQQEPEREQVQPKKKEGKISSKTAAKLSTSAKRIQKELAEITLDPPPNC 20 30 40 50 60 70 40 50 60 70 80 90 pF1KE3 CAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTR : : .:: ::. .. :: . :::: . . : ..:::::.. . : ..:: CCDS26 SAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRI--YHCNIN 80 90 100 110 120 130 100 110 120 130 140 pF1KE3 ----LCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPT---LGSIETSDFTKRQLAVQ .:: :. :.:.:: ..: .: .. :.... .:. .::: :. .:.: CCDS26 SQGVICL---DILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDR 140 150 160 170 180 190 150 160 170 180 190 200 pF1KE3 SLAFNLKDKVFCELFPEVVEEIKQKQKAQDELSSRPQTLPLPDVVPDGETHLVQNGIQLL CCDS26 MARQWTKRYAT 200 >>CCDS56244.1 UBE2E1 gene_id:7324|Hs109|chr3 (160 aa) initn: 188 init1: 161 opt: 252 Z-score: 311.1 bits: 64.5 E(33420): 5.4e-11 Smith-Waterman score: 252; 33.3% identity (60.6% similar) in 132 aa overlap (16-140:18-144) 10 20 30 40 50 pF1KE3 MSSTSSKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEG :.... : :: : : : .:: ::. .. :: . ::: CCDS56 MKEVGRPREVRGRPGKSRIQKELADITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE3 GYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTR----LCLSITDFHPDTWNPAWSVSTI : . . : :.:::::.. . : ..:: .:: :. :.:.:: ..: . CCDS56 GVFFLDITFTPEYPFKPPKVTFRTRI--YHCNINSQGVICL---DILKDNWSPALTISKV 70 80 90 100 110 120 130 140 150 160 170 pF1KE3 LTGLLSFMVEKGPT---LGSIETSDFTKRQLAVQSLAFNLKDKVFCELFPEVVEEIKQKQ : .. :.... .:. .::: :. .:.: CCDS56 LLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQWTKRYAT 120 130 140 150 160 259 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Jul 3 20:39:40 2020 done: Fri Jul 3 20:39:40 2020 Total Scan time: 1.100 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]