FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3148, 362 aa
  1>>>pF1KE3148     362 - 362 aa - 362 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6090+/-0.00103; mu= 15.4571+/- 0.062
 mean_var=72.9701+/-14.869, 0's: 0 Z-trim(104.2): 21  B-trim: 53 in 1/50
 Lambda= 0.150142
 statistics sampled from 7761 (7775) to 7761 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.239), width:  16
 Scan time:  2.170

The best scores are:                                      opt bits E(32554)
CCDS45282.1 HACD3 gene_id:51495|Hs108|chr15        ( 362) 2432 536.2 1.7e-152
CCDS43791.1 HACD4 gene_id:401494|Hs108|chr9        ( 232)  663 152.9 2.6e-37
CCDS46895.1 HACD2 gene_id:201562|Hs108|chr3        ( 254)  378 91.2 1.1e-18
CCDS7121.1 HACD1 gene_id:9200|Hs108|chr10          ( 288)  357 86.7 2.8e-17


>>CCDS45282.1 HACD3 gene_id:51495|Hs108|chr15             (362 aa)
 initn: 2432 init1: 2432 opt: 2432  Z-score: 2851.4  bits: 536.2 E(32554): 1.7e-152
Smith-Waterman score: 2432; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362)

               10        20        30        40        50        60
pF1KE3 MENQVLTPHVYWAQRHRELYLRVELSDVQNPAISITENVLHFKAQGHGAKGDNVYEFHLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MENQVLTPHVYWAQRHRELYLRVELSDVQNPAISITENVLHFKAQGHGAKGDNVYEFHLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 FLDLVKPEPVYKLTQRQVNITVQKKVSQWWERLTKQEKRPLFLAPDFDRWLDESDAEMEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 FLDLVKPEPVYKLTQRQVNITVQKKVSQWWERLTKQEKRPLFLAPDFDRWLDESDAEMEL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 RAKEEERLNKLRLESEGSPETLTNLRKGYLFMYNLVQFLGFSWIFVNLTVRFCILGKESF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RAKEEERLNKLRLESEGSPETLTNLRKGYLFMYNLVQFLGFSWIFVNLTVRFCILGKESF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 YDTFHTVADMMYFCQMLAVVETINAAIGVTTSPVLPSLIQLLGRNFILFIIFGTMEEMQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 YDTFHTVADMMYFCQMLAVVETINAAIGVTTSPVLPSLIQLLGRNFILFIIFGTMEEMQN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 KAVVFFVFYLWSAIEIFRYSFYMLTCIDMDWKVLTWLRYTLWIPLYPLGCLAEAVSVIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KAVVFFVFYLWSAIEIFRYSFYMLTCIDMDWKVLTWLRYTLWIPLYPLGCLAEAVSVIQS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 IPIFNETGRFSFTLPYPVKIKVRFSFFLQIYLIMIFLGLYINFRHLYKQRRRRYGQKKKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IPIFNETGRFSFTLPYPVKIKVRFSFFLQIYLIMIFLGLYINFRHLYKQRRRRYGQKKKK
              310       320       330       340       350       360

         
pF1KE3 IH
       ::
CCDS45 IH
         

>>CCDS43791.1 HACD4 gene_id:401494|Hs108|chr9             (232 aa)
 initn: 559 init1: 559 opt: 663  Z-score: 783.4  bits: 152.9 E(32554): 2.6e-37
Smith-Waterman score: 663; 42.5% identity (74.9% similar) in 219 aa overlap (146-361:16-232)

         120       130       140       150       160       170     
pF1KE3 AEMELRAKEEERLNKLRLESEGSPETLTNLRKGYLFMYNLVQFLGFSWIFVNLTVRFCIL
                                     ...:::.: :.:: : ::::.:.::::  .
CCDS43                MGPLALPAWLQPRYRKNAYLFIYYLIQFCGHSWIFTNMTVRFFSF
                              10        20        30        40     

         180       190       200       210       220       230     
pF1KE3 GKESFYDTFHTVADMMYFCQMLAVVETINAAIGVTTSPVLPSLIQLLGRNFILFIIFGTM
       ::.:. :::.... .: .:: ....: ..  .:. .. .:: ..::  : .:::... ..
CCDS43 GKDSMVDTFYAIGLVMRLCQSVSLLELLHIYVGIESNHLLPRFLQLTERIIILFVVITSQ
          50        60        70        80        90       100     

         240       250       260       270       280       290     
pF1KE3 EEMQNKAVVFFVFYLWSAIEIFRYSFYMLTCIDMDWKVLTWLRYTLWIPLYPLGCLAEAV
       ::.:.: ::  .: .:. ... ::.. ::. : ... :::::  :::.:.:::  :::: 
CCDS43 EEVQEKYVVCVLFVFWNLLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAF
         110       120       130       140       150       160     

         300       310       320       330       340       350     
pF1KE3 SVIQSIPIFNETGRFSFTLPYPVKIKVRFSFFLQIYLIMIFLGLYINFRHLYKQRRRRYG
       .. ::.: :.  : .:  ::. ..:   : . :.:::.:.:.:.:... :::..::   :
CCDS43 AIYQSLPYFESFGTYSTKLPFDLSI--YFPYVLKIYLMMLFIGMYFTYSHLYSERRDILG
         170       180       190         200       210       220   

            360  
pF1KE3 Q---KKKKIH
           ::::. 
CCDS43 IFPIKKKKM 
           230   

>>CCDS46895.1 HACD2 gene_id:201562|Hs108|chr3             (254 aa)
 initn: 258 init1: 194 opt: 378  Z-score: 449.2  bits: 91.2 E(32554): 1.1e-18
Smith-Waterman score: 378; 28.6% identity (65.2% similar) in 210 aa overlap (145-352:37-242)

          120       130       140       150       160       170    
pF1KE3 DAEMELRAKEEERLNKLRLESEGSPETLTNLRKGYLFMYNLVQFLGFSWIFVNLTVRFCI
                                     :  .:: .::.:.  :  :. . . .    
CCDS46 TAAAKGNGGGGGRAGAGDASGTRKKKGPGPLATAYLVIYNVVMTAG--WLVIAVGLVRAY
         10        20        30        40        50          60    

          180       190       200       210       220       230    
pF1KE3 LGKESFYDTFHTVADMMYFCQMLAVVETINAAIGVTTSPVLPSLIQLLGRNFILFIIFGT
       :.: :... ....   . : :  :..: .. :::.. : :. . .:...: :... .  .
CCDS46 LAKGSYHSLYYSIEKPLKFFQTGALLEILHCAIGIVPSSVVLTSFQVMSRVFLIWAVTHS
           70        80        90       100       110       120    

          240       250       260       270       280       290    
pF1KE3 MEEMQNKAVVFFVFYLWSAIEIFRYSFYMLTCIDMDWKVLTWLRYTLWIPLYPLGCLAEA
       ..:.:..  :..    :.  ::.::::: .. ..    .. : ::::.: :::.:  .: 
CCDS46 VKEVQSEDSVLLFVIAWTITEIIRYSFYTFSLLNHLPYLIKWARYTLFIVLYPMGVSGEL
          130       140       150       160       170       180    

          300       310       320       330        340        350  
pF1KE3 VSVIQSIPIFNETGRFSFTLPYPVKIKVRFSFFLQIYLIMI-FLGLYIN-FRHLYKQRRR
       ...  ..:.  ..: .:..::   : .  :...  . :::: .. .. . . :. .:::.
CCDS46 LTIYAALPFVRQAGLYSISLPN--KYNFSFDYYAFLILIMISYIPIFPQLYFHMIHQRRK
          190       200         210       220       230       240  

            360    
pF1KE3 RYGQKKKKIH  
                   
CCDS46 ILSHTEEHKKFE
            250    

>>CCDS7121.1 HACD1 gene_id:9200|Hs108|chr10               (288 aa)
 initn: 285 init1: 230 opt: 357  Z-score: 423.8  bits: 86.7 E(32554): 2.8e-17
Smith-Waterman score: 357; 27.8% identity (61.0% similar) in 223 aa overlap (134-352:60-276)

           110       120       130       140       150       160   
pF1KE3 APDFDRWLDESDAEMELRAKEEERLNKLRLESEGSPETLTNLRKGYLFMYNLVQFLGFSW
                                     :. :  . :  :  ..: .:....  :  :
CCDS71 SPTSPRCAATMASSDEDGTNGGASEAGEDREAPGERRRLGVLATAWLTFYDIAMTAG--W
      30        40        50        60        70        80         

            170       180       190       200       210       220  
pF1KE3 IFVNLT-VRFCILGKESFYDTFHTVADMMYFCQMLAVVETINAAIGVTTSPVLPSLIQLL
       . . .. :::  . : .    ....   . : : .:..: ..  ::.. . :. . .:. 
CCDS71 LVLAIAMVRF-YMEKGTHRGLYKSIQKTLKFFQTFALLEIVHCLIGIVPTSVIVTGVQVS
        90        100       110       120       130       140      

            230       240       250       260       270       280  
pF1KE3 GRNFILFIIFGTMEEMQNKAVVFFVFYLWSAIEIFRYSFYMLTCIDMDWKVLTWLRYTLW
       .: :....:  ... .::.  : . .  :.. :: ::::: .. .:     . : ::...
CCDS71 SRIFMVWLITHSIKPIQNEESVVLFLVAWTVTEITRYSFYTFSLLDHLPYFIKWARYNFF
        150       160       170       180       190       200      

            290       300       310       320       330            
pF1KE3 IPLYPLGCLAEAVSVIQSIPIFNETGRFSFTLPYPVKIKVRFSFFLQIYL---IMIFLGL
       : :::.:  .: ...  ..:  ..:: ::. ::   ...  . .:: : .   : .:  :
CCDS71 IILYPVGVAGELLTIYAALPHVKKTGMFSIRLPNKYNVSFDYYYFLLITMASYIPLFPQL
        210       220       230       240       250       260      

     340       350       360    
pF1KE3 YINFRHLYKQRRRRYGQKKKKIH  
       :.   :. .:::.            
CCDS71 YF---HMLRQRRKVLHGEVIVEKDD
           270       280        




362 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov 18 17:34:14 2016 done: Fri Nov 18 17:34:14 2016
 Total Scan time:  2.170 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]