FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3209, 478 aa 1>>>pF1KE3209 478 - 478 aa - 478 aa Library: /omim/omim.rfq.tfa 64536644 residues in 91102 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8209+/-0.000297; mu= 11.9058+/- 0.018 mean_var=127.9658+/-26.461, 0's: 0 Z-trim(120.8): 78 B-trim: 1962 in 1/52 Lambda= 0.113378 statistics sampled from 37679 (37760) to 37679 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.414), width: 16 Scan time: 4.840 The best scores are: opt bits E(91102) NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 3318 553.8 4.1e-157 NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 1128 195.6 2.7e-49 NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 394 75.5 3.4e-13 NP_001191 (OMIM: 112261,112600,235200,617877) bone ( 396) 390 74.8 5.2e-13 NP_001334844 (OMIM: 112262,600625,607932) bone mor ( 345) 386 74.1 7.4e-13 NP_001334846 (OMIM: 112262,600625,607932) bone mor ( 345) 386 74.1 7.4e-13 NP_001334842 (OMIM: 112262,600625,607932) bone mor ( 345) 386 74.1 7.4e-13 XP_006714354 (OMIM: 112263) bone morphogenetic pro ( 439) 387 74.3 8e-13 NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 386 74.2 8.4e-13 NP_001334843 (OMIM: 112262,600625,607932) bone mor ( 408) 386 74.2 8.4e-13 NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 386 74.2 8.4e-13 NP_570912 (OMIM: 112262,600625,607932) bone morpho ( 408) 386 74.2 8.4e-13 NP_001334845 (OMIM: 112262,600625,607932) bone mor ( 408) 386 74.2 8.4e-13 NP_001334841 (OMIM: 112262,600625,607932) bone mor ( 455) 386 74.2 9.2e-13 XP_011540326 (OMIM: 602284) bone morphogenetic pro ( 427) 385 74.0 9.8e-13 NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 385 74.1 1.1e-12 NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 385 74.1 1.1e-12 NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 375 72.4 3.1e-12 NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 369 71.4 6.3e-12 NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 368 71.3 7e-12 NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 365 70.8 9.8e-12 NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 365 70.8 1.1e-11 NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 338 66.3 1.8e-10 NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 323 63.9 1.1e-09 NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 317 62.8 2e-09 NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 308 61.4 6e-09 XP_024303796 (OMIM: 270100,601265) nodal homolog i ( 214) 302 60.2 7e-09 NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 302 60.2 7e-09 NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 302 60.4 1e-08 NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 292 58.8 3.6e-08 NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 270 55.1 3.8e-07 XP_016867665 (OMIM: 147290) inhibin beta A chain i ( 426) 269 55.0 5e-07 NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 269 55.0 5e-07 XP_016867664 (OMIM: 147290) inhibin beta A chain i ( 483) 269 55.1 5.5e-07 XP_016867663 (OMIM: 147290) inhibin beta A chain i ( 548) 269 55.1 6.1e-07 XP_024305067 (OMIM: 602284) bone morphogenetic pro ( 262) 262 53.7 7.6e-07 NP_005439 (OMIM: 300247,300510) bone morphogenetic ( 392) 263 54.0 9.3e-07 NP_005802 (OMIM: 603936) growth/differentiation fa ( 407) 263 54.0 9.6e-07 XP_006719257 (OMIM: 603936) growth/differentiation ( 407) 263 54.0 9.6e-07 XP_011540324 (OMIM: 602284) bone morphogenetic pro ( 357) 262 53.8 9.7e-07 NP_005250 (OMIM: 601788,614160) growth/differentia ( 375) 256 52.9 2e-06 NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 253 52.4 2.7e-06 XP_016857644 (OMIM: 602284) bone morphogenetic pro ( 382) 253 52.4 2.8e-06 NP_004855 (OMIM: 605312) growth/differentiation fa ( 308) 236 49.5 1.6e-05 XP_024307557 (OMIM: 605312) growth/differentiation ( 308) 236 49.5 1.6e-05 XP_011541613 (OMIM: 601918) growth/differentiation ( 276) 233 49.0 2.1e-05 XP_005272014 (OMIM: 601918) growth/differentiation ( 366) 233 49.1 2.6e-05 NP_001275753 (OMIM: 601918) growth/differentiation ( 366) 233 49.1 2.6e-05 XP_011541611 (OMIM: 601918) growth/differentiation ( 366) 233 49.1 2.6e-05 NP_001275755 (OMIM: 601918) growth/differentiation ( 366) 233 49.1 2.6e-05 >>NP_004953 (OMIM: 601361) growth/differentiation factor (478 aa) initn: 3318 init1: 3318 opt: 3318 Z-score: 2942.3 bits: 553.8 E(91102): 4.1e-157 Smith-Waterman score: 3318; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KE3 MAHVPARTSPGPGPQLLLLLLPLFLLLLRDVAGSHRAPAWSALPAAADGLQGDRDLQRHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAHVPARTSPGPGPQLLLLLLPLFLLLLRDVAGSHRAPAWSALPAAADGLQGDRDLQRHP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 GDAAATLGPSAQDMVAVHMHRLYEKYSRQGARPGGGNTVRSFRARLEVVDQKAVYFFNLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GDAAATLGPSAQDMVAVHMHRLYEKYSRQGARPGGGNTVRSFRARLEVVDQKAVYFFNLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 SMQDSEMILTATFHFYSEPPRWPRALEVLCKPRAKNASGRPLPLGPPTRQHLLFRSLSQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SMQDSEMILTATFHFYSEPPRWPRALEVLCKPRAKNASGRPLPLGPPTRQHLLFRSLSQN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TATQGLLRGAMALAPPPRGLWQAKDISPIVKAARRDGELLLSAQLDSEERDPGVPRPSPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TATQGLLRGAMALAPPPRGLWQAKDISPIVKAARRDGELLLSAQLDSEERDPGVPRPSPY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 APYILVYANDLAISEPNSVAVTLQRYDPFPAGDPEPRAAPNNSADPRVRRAAQATGPLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 APYILVYANDLAISEPNSVAVTLQRYDPFPAGDPEPRAAPNNSADPRVRRAAQATGPLQD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 NELPGLDERPPRAHAQHFHKHQLWPSPFRALKPRPGRKDRRKKGQEVFMAASQVLDFDEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NELPGLDERPPRAHAQHFHKHQLWPSPFRALKPRPGRKDRRKKGQEVFMAASQVLDFDEK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 TMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPS 370 380 390 400 410 420 430 440 450 460 470 pF1KE3 NHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCACR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCACR 430 440 450 460 470 >>NP_001192 (OMIM: 112263) bone morphogenetic protein 3 (472 aa) initn: 1159 init1: 793 opt: 1128 Z-score: 1006.4 bits: 195.6 E(91102): 2.7e-49 Smith-Waterman score: 1191; 47.2% identity (68.2% similar) in 462 aa overlap (60-478:37-472) 30 40 50 60 70 80 pF1KE3 DVAGSHRAPAWSALPAAADGLQGDRDLQRHPGDAAATLGPSA----QDMVAVHMHRLYEK ::: .: ::.. :: :. :: :::.. NP_001 LLFLWLGCFCVSLAQGERPKPPFPELRKAVPGDRTAGGGPDSELQPQDKVSEHMLRLYDR 10 20 30 40 50 60 90 100 110 120 pF1KE3 YSR-QGAR-PGG---------------GNTVRSFRARL-EVVDQKAVYFFNLTSMQDSEM :: :.:: ::. ::::::::: :....:..:.:::::. :: NP_001 YSTVQAARTPGSLEGGSQPWRPRLLREGNTVRSFRAAAAETLERKGLYIFNLTSLTKSEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 ILTATFHFYSEPPRWPRALEVLCKPRAKNAS-GRPLPLG---PPTRQHLLFRSLSQNTA- ::.::..: : . : : . :. : :.:. . .:: : NP_001 ILSATLYF--------------CIGELGNISLSCPVSGGCSHHAQRKHIQI-DLSAWTLK 130 140 150 160 170 190 200 210 220 230 pF1KE3 ---TQGLLRGAMA--LAPPPRGL--WQAKDISPIVKAARRDGELLLSAQLDSEERD-PGV .:. : : .. .: : . : .:::. ... :... :.:.. .. :. :. : NP_001 FSRNQSQLLGHLSVDMAKSHRDIMSWLSKDITQFLRKAKENEEFLIGFNITSKGRQLPKR 180 190 200 210 220 230 240 250 260 270 280 pF1KE3 PRPSPYAPYILVYANDLAISEPNSVAVTLQRYDPFPAG-----DPEPRAAPNNSADPRVR : : ::::::::: :::::.::. .:: . ::.: : . ::: : . : . NP_001 RLPFP-EPYILVYANDAAISEPESVVSSLQGHRNFPTGTVPKWDSHIRAA--LSIERRKK 240 250 260 270 280 290 300 310 320 330 340 pF1KE3 RAAQATGPLQDNELPGLDERPPRAHAQHFHKHQLWP--SPFRALKPRPGRKDRRKKGQEV :.. . :::.::::: . ...: ..: .:...:. . .:.. :: :. NP_001 RSTGVLLPLQNNELPGAE--------YQYKKDEVWEERKPYKTLQAQAPEKSKNKKKQRK 290 300 310 320 330 340 350 360 370 380 390 400 pF1KE3 F-MAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCA ::.:.:::.:..::::::: ::: :.:::::::::::::.::::::::::::::. NP_001 GPHRKSQTLQFDEQTLKKARRKQWIEPRNCARRYLKVDFADIGWSEWIISPKSFDAYYCS 350 360 370 380 390 400 410 420 430 440 450 460 pF1KE3 GACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKV :::.::::: ..:::::::::::::::..::::::::::.::.::..::.:::.:::::: NP_001 GACQFPMPKSLKPSNHATIQSIVRAVGVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKV 410 420 430 440 450 460 470 pF1KE3 YPNMSVDTCACR ::::.:..:::: NP_001 YPNMTVESCACR 470 >>NP_001711 (OMIM: 602284) bone morphogenetic protein 8B (402 aa) initn: 454 init1: 222 opt: 394 Z-score: 358.5 bits: 75.5 E(91102): 3.4e-13 Smith-Waterman score: 394; 36.1% identity (64.5% similar) in 183 aa overlap (300-477:229-401) 270 280 290 300 310 320 pF1KE3 PAGDPEPRAAPNNSADPRVRRAAQATGPLQDNELPGL-DERPPRAHAQHF--HKHQLWPS : : :: .: ::.. : : . :: NP_001 VTAASDCWLLKRHKDLGLRLYVETEDGHSVDPGLAGLLGQRAPRSQ-QPFVVTFFRASPS 200 210 220 230 240 250 330 340 350 360 370 380 pF1KE3 PFRALKP-RPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDF :.:. . :: :. . ::..:. .: ::. ...:. :: :. : :.: NP_001 PIRTPRAVRPLRRRQPKKSNELPQANRLPGIFDDVHGSHGRQ-------VCRRHELYVSF 260 270 280 290 300 310 390 400 410 420 430 440 pF1KE3 ADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIP-GIPEPCCV :.:: .:.:.:....:::: : : ::. . . .::: .::.:. ..: ..:. ::. NP_001 QDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHL--MMPDAVPKACCA 320 330 340 350 360 450 460 470 pF1KE3 PDKMNSLGVLFLDENRNVVLKVYPNMSVDTCACR : :... .::. : . ::.:. . :: : .:.: NP_001 PTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH 370 380 390 400 >>NP_001191 (OMIM: 112261,112600,235200,617877) bone mor (396 aa) initn: 498 init1: 212 opt: 390 Z-score: 355.0 bits: 74.8 E(91102): 5.2e-13 Smith-Waterman score: 390; 41.3% identity (74.4% similar) in 121 aa overlap (359-478:278-396) 330 340 350 360 370 380 pF1KE3 RALKPRPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRV-CSRRYLKVDFAD .. ..:..:: . . :.:. : :::.: NP_001 RSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSD 250 260 270 280 290 300 390 400 410 420 430 440 pF1KE3 IGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDK .:::.::..: .. :.:: : : ::. . .::: .:..: .:. ::. :::: . NP_001 VGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVN--SKIPKACCVPTE 310 320 330 340 350 360 450 460 470 pF1KE3 MNSLGVLFLDENRNVVLKVYPNMSVDTCACR ......:.::::..:::: : .: :. :.:: NP_001 LSAISMLYLDENEKVVLKNYQDMVVEGCGCR 370 380 390 >>NP_001334844 (OMIM: 112262,600625,607932) bone morphog (345 aa) initn: 409 init1: 212 opt: 386 Z-score: 352.3 bits: 74.1 E(91102): 7.4e-13 Smith-Waterman score: 386; 43.1% identity (74.1% similar) in 116 aa overlap (363-478:236-345) 340 350 360 370 380 390 pF1KE3 PRPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNE :.::.:. . : :. : :::.:.:::. NP_001 RPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKN----KNCRRHSLYVDFSDVGWND 210 220 230 240 250 260 400 410 420 430 440 450 pF1KE3 WIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLG ::..: ...:.:: : : ::. . .::: .:..: .:. .::. :::: ...... NP_001 WIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVN--SSIPKACCVPTELSAIS 270 280 290 300 310 460 470 pF1KE3 VLFLDENRNVVLKVYPNMSVDTCACR .:.::: .:::: : .: :. :.:: NP_001 MLYLDEYDKVVLKNYQEMVVEGCGCR 320 330 340 >>NP_001334846 (OMIM: 112262,600625,607932) bone morphog (345 aa) initn: 409 init1: 212 opt: 386 Z-score: 352.3 bits: 74.1 E(91102): 7.4e-13 Smith-Waterman score: 386; 43.1% identity (74.1% similar) in 116 aa overlap (363-478:236-345) 340 350 360 370 380 390 pF1KE3 PRPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNE :.::.:. . : :. : :::.:.:::. NP_001 RPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKN----KNCRRHSLYVDFSDVGWND 210 220 230 240 250 260 400 410 420 430 440 450 pF1KE3 WIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLG ::..: ...:.:: : : ::. . .::: .:..: .:. .::. :::: ...... NP_001 WIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVN--SSIPKACCVPTELSAIS 270 280 290 300 310 460 470 pF1KE3 VLFLDENRNVVLKVYPNMSVDTCACR .:.::: .:::: : .: :. :.:: NP_001 MLYLDEYDKVVLKNYQEMVVEGCGCR 320 330 340 >>NP_001334842 (OMIM: 112262,600625,607932) bone morphog (345 aa) initn: 409 init1: 212 opt: 386 Z-score: 352.3 bits: 74.1 E(91102): 7.4e-13 Smith-Waterman score: 386; 43.1% identity (74.1% similar) in 116 aa overlap (363-478:236-345) 340 350 360 370 380 390 pF1KE3 PRPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNE :.::.:. . : :. : :::.:.:::. NP_001 RPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKN----KNCRRHSLYVDFSDVGWND 210 220 230 240 250 260 400 410 420 430 440 450 pF1KE3 WIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLG ::..: ...:.:: : : ::. . .::: .:..: .:. .::. :::: ...... NP_001 WIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVN--SSIPKACCVPTELSAIS 270 280 290 300 310 460 470 pF1KE3 VLFLDENRNVVLKVYPNMSVDTCACR .:.::: .:::: : .: :. :.:: NP_001 MLYLDEYDKVVLKNYQEMVVEGCGCR 320 330 340 >>XP_006714354 (OMIM: 112263) bone morphogenetic protein (439 aa) initn: 749 init1: 381 opt: 387 Z-score: 351.8 bits: 74.3 E(91102): 8e-13 Smith-Waterman score: 878; 40.7% identity (61.0% similar) in 462 aa overlap (60-478:37-439) 30 40 50 60 70 80 pF1KE3 DVAGSHRAPAWSALPAAADGLQGDRDLQRHPGDAAATLGPSA----QDMVAVHMHRLYEK ::: .: ::.. :: :. :: :::.. XP_006 LLFLWLGCFCVSLAQGERPKPPFPELRKAVPGDRTAGGGPDSELQPQDKVSEHMLRLYDR 10 20 30 40 50 60 90 100 110 120 pF1KE3 YSR-QGAR-PGG---------------GNTVRSFRARL-EVVDQKAVYFFNLTSMQDSEM :: :.:: ::. ::::::::: :....:..:.:::::. :: XP_006 YSTVQAARTPGSLEGGSQPWRPRLLREGNTVRSFRAAAAETLERKGLYIFNLTSLTKSEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 ILTATFHFYSEPPRWPRALEVLCKPRAKNAS-GRPLPLG---PPTRQHLLFRSLSQNTA- ::.::..: : . : : . :. : :.:. . .:: : XP_006 ILSATLYF--------------CIGELGNISLSCPVSGGCSHHAQRKHIQI-DLSAWTLK 130 140 150 160 170 190 200 210 220 230 pF1KE3 ---TQGLLRGAMA--LAPPPRGL--WQAKDISPIVKAARRDGELLLSAQLDSEERD-PGV .:. : : .. .: : . : .:::. ... :... :.:.. .. :. :. : XP_006 FSRNQSQLLGHLSVDMAKSHRDIMSWLSKDITQLLRKAKENEEFLIGFNITSKGRQLPKR 180 190 200 210 220 230 240 250 260 270 280 pF1KE3 PRPSPYAPYILVYANDLAISEPNSVAVTLQRYDPFPAG-----DPEPRAAPNNSADPRVR : : ::::::::: :::::.::. .:: . ::.: : . ::: : . : . XP_006 RLPFP-EPYILVYANDAAISEPESVVSSLQGHRNFPTGTVPKWDSHIRAA--LSIERRKK 240 250 260 270 280 290 300 310 320 330 340 pF1KE3 RAAQATGPLQDNELPGLDERPPRAHAQHFHKHQLWP--SPFRALKPRPGRKDRRKKGQEV :.. . :::.::::: . ...: ..: .:...:. . .:.. :: :. XP_006 RSTGVLLPLQNNELPGAE--------YQYKKDEVWEERKPYKTLQAQAPEKSKNKKKQRK 290 300 310 320 330 340 350 360 370 380 390 400 pF1KE3 F-MAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCA ::.:.:::.:..::::::: ::: :.::::: XP_006 GPHRKSQTLQFDEQTLKKARRKQWIEPRNCARRYLKS----------------------- 350 360 370 410 420 430 440 450 460 pF1KE3 GACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKV ..:::::::::::::::..::::::::::.::.::..::.:::.:::::: XP_006 ----------LKPSNHATIQSIVRAVGVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKV 380 390 400 410 420 470 pF1KE3 YPNMSVDTCACR ::::.:..:::: XP_006 YPNMTVESCACR 430 >>NP_570911 (OMIM: 112262,600625,607932) bone morphogene (408 aa) initn: 409 init1: 212 opt: 386 Z-score: 351.3 bits: 74.2 E(91102): 8.4e-13 Smith-Waterman score: 386; 43.1% identity (74.1% similar) in 116 aa overlap (363-478:299-408) 340 350 360 370 380 390 pF1KE3 PRPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNE :.::.:. . : :. : :::.:.:::. NP_570 RPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKN----KNCRRHSLYVDFSDVGWND 270 280 290 300 310 320 400 410 420 430 440 450 pF1KE3 WIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLG ::..: ...:.:: : : ::. . .::: .:..: .:. .::. :::: ...... NP_570 WIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVN--SSIPKACCVPTELSAIS 330 340 350 360 370 380 460 470 pF1KE3 VLFLDENRNVVLKVYPNMSVDTCACR .:.::: .:::: : .: :. :.:: NP_570 MLYLDEYDKVVLKNYQEMVVEGCGCR 390 400 >>NP_001334843 (OMIM: 112262,600625,607932) bone morphog (408 aa) initn: 409 init1: 212 opt: 386 Z-score: 351.3 bits: 74.2 E(91102): 8.4e-13 Smith-Waterman score: 386; 43.1% identity (74.1% similar) in 116 aa overlap (363-478:299-408) 340 350 360 370 380 390 pF1KE3 PRPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNE :.::.:. . : :. : :::.:.:::. NP_001 RPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKN----KNCRRHSLYVDFSDVGWND 270 280 290 300 310 320 400 410 420 430 440 450 pF1KE3 WIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLG ::..: ...:.:: : : ::. . .::: .:..: .:. .::. :::: ...... NP_001 WIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVN--SSIPKACCVPTELSAIS 330 340 350 360 370 380 460 470 pF1KE3 VLFLDENRNVVLKVYPNMSVDTCACR .:.::: .:::: : .: :. :.:: NP_001 MLYLDEYDKVVLKNYQEMVVEGCGCR 390 400 478 residues in 1 query sequences 64536644 residues in 91102 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Jun 13 19:13:29 2018 done: Wed Jun 13 19:13:30 2018 Total Scan time: 4.840 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]