FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3218, 495 aa 1>>>pF1KE3218 495 - 495 aa - 495 aa Library: /omim/omim.rfq.tfa 65638526 residues in 92875 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7789+/-0.000333; mu= 17.1209+/- 0.021 mean_var=111.7867+/-23.152, 0's: 0 Z-trim(116.2): 110 B-trim: 0 in 0/51 Lambda= 0.121305 statistics sampled from 28342 (28461) to 28342 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.306), width: 16 Scan time: 4.780 The best scores are: opt bits E(92875) NP_056419 (OMIM: 616372) DDB1- and CUL4-associated ( 495) 3354 598.1 2e-170 XP_016876697 (OMIM: 616372) DDB1- and CUL4-associa ( 495) 3354 598.1 2e-170 XP_016876696 (OMIM: 616372) DDB1- and CUL4-associa ( 495) 3354 598.1 2e-170 XP_016876691 (OMIM: 616372) DDB1- and CUL4-associa ( 496) 3342 596.0 8.5e-170 XP_016876695 (OMIM: 616372) DDB1- and CUL4-associa ( 496) 3342 596.0 8.5e-170 XP_016876694 (OMIM: 616372) DDB1- and CUL4-associa ( 496) 3342 596.0 8.5e-170 XP_016876692 (OMIM: 616372) DDB1- and CUL4-associa ( 496) 3342 596.0 8.5e-170 NP_001339378 (OMIM: 616372) DDB1- and CUL4-associa ( 496) 3342 596.0 8.5e-170 XP_016876690 (OMIM: 616372) DDB1- and CUL4-associa ( 496) 3342 596.0 8.5e-170 NP_001156980 (OMIM: 616372) DDB1- and CUL4-associa ( 489) 3278 584.8 2e-166 NP_001339377 (OMIM: 616372) DDB1- and CUL4-associa ( 475) 2926 523.2 6.8e-148 XP_016876698 (OMIM: 616372) DDB1- and CUL4-associa ( 476) 2914 521.1 2.9e-147 XP_016876703 (OMIM: 616372) DDB1- and CUL4-associa ( 473) 2828 506.1 9.9e-143 XP_016876702 (OMIM: 616372) DDB1- and CUL4-associa ( 474) 2816 504.0 4.2e-142 NP_001156981 (OMIM: 616372) DDB1- and CUL4-associa ( 474) 2816 504.0 4.2e-142 XP_016876701 (OMIM: 616372) DDB1- and CUL4-associa ( 474) 2816 504.0 4.2e-142 NP_851937 (OMIM: 616372) DDB1- and CUL4-associated ( 395) 2642 473.4 5.5e-133 NP_851938 (OMIM: 616372) DDB1- and CUL4-associated ( 435) 2135 384.8 3e-106 XP_016876704 (OMIM: 616372) DDB1- and CUL4-associa ( 280) 1915 346.1 8.6e-95 NP_001339376 (OMIM: 616372) DDB1- and CUL4-associa ( 281) 1903 344.0 3.7e-94 >>NP_056419 (OMIM: 616372) DDB1- and CUL4-associated fac (495 aa) initn: 3354 init1: 3354 opt: 3354 Z-score: 3181.4 bits: 598.1 E(92875): 2e-170 Smith-Waterman score: 3354; 99.4% identity (99.6% similar) in 495 aa overlap (1-495:1-495) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHPGIDRPGMLCSFRIPGAWSCAWSLNIQANNCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HILLCLMGLAETPGCATLLPASLFVNSHPGIDRPGMLCSFRIPGAWSCAWSLNIQANNCF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 STGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQGK :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: NP_056 STGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 GWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLPL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 HVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAPG :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_056 HVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAPG 430 440 450 460 470 480 490 pF1KE3 LLMAVGQDLYCYSYS ::::::::::::::: NP_056 LLMAVGQDLYCYSYS 490 >>XP_016876697 (OMIM: 616372) DDB1- and CUL4-associated (495 aa) initn: 3354 init1: 3354 opt: 3354 Z-score: 3181.4 bits: 598.1 E(92875): 2e-170 Smith-Waterman score: 3354; 99.4% identity (99.6% similar) in 495 aa overlap (1-495:1-495) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHPGIDRPGMLCSFRIPGAWSCAWSLNIQANNCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HILLCLMGLAETPGCATLLPASLFVNSHPGIDRPGMLCSFRIPGAWSCAWSLNIQANNCF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 STGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQGK :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: XP_016 STGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 GWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLPL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 HVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAPG :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: XP_016 HVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAPG 430 440 450 460 470 480 490 pF1KE3 LLMAVGQDLYCYSYS ::::::::::::::: XP_016 LLMAVGQDLYCYSYS 490 >>XP_016876696 (OMIM: 616372) DDB1- and CUL4-associated (495 aa) initn: 3354 init1: 3354 opt: 3354 Z-score: 3181.4 bits: 598.1 E(92875): 2e-170 Smith-Waterman score: 3354; 99.4% identity (99.6% similar) in 495 aa overlap (1-495:1-495) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHPGIDRPGMLCSFRIPGAWSCAWSLNIQANNCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HILLCLMGLAETPGCATLLPASLFVNSHPGIDRPGMLCSFRIPGAWSCAWSLNIQANNCF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 STGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQGK :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: XP_016 STGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 GWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLPL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 HVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAPG :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: XP_016 HVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAPG 430 440 450 460 470 480 490 pF1KE3 LLMAVGQDLYCYSYS ::::::::::::::: XP_016 LLMAVGQDLYCYSYS 490 >>XP_016876691 (OMIM: 616372) DDB1- and CUL4-associated (496 aa) initn: 3340 init1: 1815 opt: 3342 Z-score: 3170.0 bits: 596.0 E(92875): 8.5e-170 Smith-Waterman score: 3342; 99.2% identity (99.4% similar) in 496 aa overlap (1-495:1-496) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHP-GIDRPGMLCSFRIPGAWSCAWSLNIQANNC ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_016 HILLCLMGLAETPGCATLLPASLFVNSHPAGIDRPGMLCSFRIPGAWSCAWSLNIQANNC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_016 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 LHVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 LHVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP 430 440 450 460 470 480 480 490 pF1KE3 GLLMAVGQDLYCYSYS :::::::::::::::: XP_016 GLLMAVGQDLYCYSYS 490 >>XP_016876695 (OMIM: 616372) DDB1- and CUL4-associated (496 aa) initn: 3340 init1: 1815 opt: 3342 Z-score: 3170.0 bits: 596.0 E(92875): 8.5e-170 Smith-Waterman score: 3342; 99.2% identity (99.4% similar) in 496 aa overlap (1-495:1-496) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHP-GIDRPGMLCSFRIPGAWSCAWSLNIQANNC ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_016 HILLCLMGLAETPGCATLLPASLFVNSHPAGIDRPGMLCSFRIPGAWSCAWSLNIQANNC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_016 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 LHVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 LHVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP 430 440 450 460 470 480 480 490 pF1KE3 GLLMAVGQDLYCYSYS :::::::::::::::: XP_016 GLLMAVGQDLYCYSYS 490 >>XP_016876694 (OMIM: 616372) DDB1- and CUL4-associated (496 aa) initn: 3340 init1: 1815 opt: 3342 Z-score: 3170.0 bits: 596.0 E(92875): 8.5e-170 Smith-Waterman score: 3342; 99.2% identity (99.4% similar) in 496 aa overlap (1-495:1-496) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHP-GIDRPGMLCSFRIPGAWSCAWSLNIQANNC ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_016 HILLCLMGLAETPGCATLLPASLFVNSHPAGIDRPGMLCSFRIPGAWSCAWSLNIQANNC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_016 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 LHVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 LHVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP 430 440 450 460 470 480 480 490 pF1KE3 GLLMAVGQDLYCYSYS :::::::::::::::: XP_016 GLLMAVGQDLYCYSYS 490 >>XP_016876692 (OMIM: 616372) DDB1- and CUL4-associated (496 aa) initn: 3340 init1: 1815 opt: 3342 Z-score: 3170.0 bits: 596.0 E(92875): 8.5e-170 Smith-Waterman score: 3342; 99.2% identity (99.4% similar) in 496 aa overlap (1-495:1-496) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHP-GIDRPGMLCSFRIPGAWSCAWSLNIQANNC ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_016 HILLCLMGLAETPGCATLLPASLFVNSHPAGIDRPGMLCSFRIPGAWSCAWSLNIQANNC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_016 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 LHVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 LHVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP 430 440 450 460 470 480 480 490 pF1KE3 GLLMAVGQDLYCYSYS :::::::::::::::: XP_016 GLLMAVGQDLYCYSYS 490 >>NP_001339378 (OMIM: 616372) DDB1- and CUL4-associated (496 aa) initn: 3340 init1: 1815 opt: 3342 Z-score: 3170.0 bits: 596.0 E(92875): 8.5e-170 Smith-Waterman score: 3342; 99.2% identity (99.4% similar) in 496 aa overlap (1-495:1-496) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHP-GIDRPGMLCSFRIPGAWSCAWSLNIQANNC ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: NP_001 HILLCLMGLAETPGCATLLPASLFVNSHPAGIDRPGMLCSFRIPGAWSCAWSLNIQANNC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 LHVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_001 LHVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP 430 440 450 460 470 480 480 490 pF1KE3 GLLMAVGQDLYCYSYS :::::::::::::::: NP_001 GLLMAVGQDLYCYSYS 490 >>XP_016876690 (OMIM: 616372) DDB1- and CUL4-associated (496 aa) initn: 3340 init1: 1815 opt: 3342 Z-score: 3170.0 bits: 596.0 E(92875): 8.5e-170 Smith-Waterman score: 3342; 99.2% identity (99.4% similar) in 496 aa overlap (1-495:1-496) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHP-GIDRPGMLCSFRIPGAWSCAWSLNIQANNC ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_016 HILLCLMGLAETPGCATLLPASLFVNSHPAGIDRPGMLCSFRIPGAWSCAWSLNIQANNC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQG ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_016 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 LHVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 LHVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP 430 440 450 460 470 480 480 490 pF1KE3 GLLMAVGQDLYCYSYS :::::::::::::::: XP_016 GLLMAVGQDLYCYSYS 490 >>NP_001156980 (OMIM: 616372) DDB1- and CUL4-associated (489 aa) initn: 2890 init1: 1815 opt: 3278 Z-score: 3109.6 bits: 584.8 E(92875): 2e-166 Smith-Waterman score: 3278; 98.0% identity (98.0% similar) in 496 aa overlap (1-495:1-489) 10 20 30 40 50 60 pF1KE3 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TNSDRLFTVNDVTVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDS 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 HILLCLMGLAETPGCATLLPASLFVNSHP-GIDRPGMLCSFRIPGAWSCAWSLNIQANNC ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: NP_001 HILLCLMGLAETPGCATLLPASLFVNSHPAGIDRPGMLCSFRIPGAWSCAWSLNIQANNC 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFAFMAPLLFNGCRSGEIFAIDLRCGNQG :::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_001 FSTGLSRRVLLTNVVTGHRQSFGTNSDVLA-------PLLFNGCRSGEIFAIDLRCGNQG 310 320 330 340 350 360 370 380 390 400 410 pF1KE3 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLP 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE3 LHVHEEEGILVAVGQDCYTIIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_001 LHVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAP 420 430 440 450 460 470 480 490 pF1KE3 GLLMAVGQDLYCYSYS :::::::::::::::: NP_001 GLLMAVGQDLYCYSYS 480 495 residues in 1 query sequences 65638526 residues in 92875 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Apr 23 11:11:42 2019 done: Tue Apr 23 11:11:43 2019 Total Scan time: 4.780 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]