Result of FASTA (omim) for
pF1KE3228
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3228, 520 aa
1>>>pF1KE3228 520 - 520 aa - 520 aa
Library: /omim/omim.rfq.tfa
65951994 residues in 93482 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0481+/-0.00033; mu= 15.5829+/- 0.021
mean_var=92.9775+/-18.811, 0's: 0 Z-trim(116.1): 40 B-trim: 0 in 0/52
Lambda= 0.133010
statistics sampled from 28180 (28220) to 28180 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.302), width: 16
Scan time: 4.880
The best scores are: opt bits E(93482)
NP_004557 (OMIM: 605319) 6-phosphofructo-2-kinase/ ( 520) 3488 679.7 6.3e-195
NP_001350474 (OMIM: 605319) 6-phosphofructo-2-kina ( 568) 3402 663.2 6.3e-190
NP_001300992 (OMIM: 605319) 6-phosphofructo-2-kina ( 514) 3398 662.4 9.8e-190
NP_001138915 (OMIM: 605319) 6-phosphofructo-2-kina ( 500) 3310 645.5 1.2e-184
NP_001269559 (OMIM: 605319) 6-phosphofructo-2-kina ( 534) 3309 645.3 1.4e-184
XP_016871816 (OMIM: 605319) 6-phosphofructo-2-kina ( 548) 3224 629.0 1.2e-179
NP_001309945 (OMIM: 605319) 6-phosphofructo-2-kina ( 494) 3220 628.2 1.8e-179
XP_005252521 (OMIM: 605319) 6-phosphofructo-2-kina ( 462) 3003 586.6 5.9e-167
XP_016871818 (OMIM: 605319) 6-phosphofructo-2-kina ( 501) 2382 467.4 4.7e-131
XP_016871815 (OMIM: 605319) 6-phosphofructo-2-kina ( 549) 2296 451.0 4.7e-126
XP_024303424 (OMIM: 171835) 6-phosphofructo-2-kina ( 472) 2292 450.1 7.1e-126
NP_006203 (OMIM: 171835) 6-phosphofructo-2-kinase/ ( 505) 2292 450.2 7.5e-126
XP_024303422 (OMIM: 171835) 6-phosphofructo-2-kina ( 505) 2292 450.2 7.5e-126
XP_024303423 (OMIM: 171835) 6-phosphofructo-2-kina ( 505) 2292 450.2 7.5e-126
NP_001309946 (OMIM: 605319) 6-phosphofructo-2-kina ( 337) 2268 445.4 1.3e-124
XP_024303425 (OMIM: 171835) 6-phosphofructo-2-kina ( 471) 2231 438.4 2.4e-122
NP_001018063 (OMIM: 171835) 6-phosphofructo-2-kina ( 471) 2231 438.4 2.4e-122
NP_004558 (OMIM: 605320) 6-phosphofructo-2-kinase/ ( 469) 2230 438.2 2.7e-122
NP_002616 (OMIM: 311790) 6-phosphofructo-2-kinase/ ( 471) 2226 437.5 4.6e-122
XP_024303805 (OMIM: 605319) 6-phosphofructo-2-kina ( 385) 2182 429.0 1.4e-119
XP_011517795 (OMIM: 605319) 6-phosphofructo-2-kina ( 427) 2180 428.6 1.9e-119
XP_016871817 (OMIM: 605319) 6-phosphofructo-2-kina ( 533) 2180 428.7 2.3e-119
NP_001304064 (OMIM: 605320) 6-phosphofructo-2-kina ( 462) 2170 426.7 7.8e-119
XP_024308157 (OMIM: 311790) 6-phosphofructo-2-kina ( 448) 2167 426.1 1.1e-118
XP_011532131 (OMIM: 605320) 6-phosphofructo-2-kina ( 471) 2165 425.8 1.5e-118
NP_001304065 (OMIM: 605320) 6-phosphofructo-2-kina ( 458) 2163 425.4 2e-118
XP_024309363 (OMIM: 605320) 6-phosphofructo-2-kina ( 435) 2161 425.0 2.5e-118
XP_016862105 (OMIM: 605320) 6-phosphofructo-2-kina ( 457) 2161 425.0 2.6e-118
NP_001304063 (OMIM: 605320) 6-phosphofructo-2-kina ( 498) 2161 425.0 2.7e-118
XP_016862106 (OMIM: 605320) 6-phosphofructo-2-kina ( 453) 2159 424.6 3.3e-118
XP_016862103 (OMIM: 605320) 6-phosphofructo-2-kina ( 493) 2157 424.3 4.6e-118
XP_016885067 (OMIM: 311790) 6-phosphofructo-2-kina ( 449) 1955 385.5 2e-106
XP_016885065 (OMIM: 311790) 6-phosphofructo-2-kina ( 500) 1955 385.5 2.2e-106
NP_001258734 (OMIM: 311790) 6-phosphofructo-2-kina ( 406) 1941 382.8 1.2e-105
NP_001258733 (OMIM: 311790) 6-phosphofructo-2-kina ( 449) 1840 363.4 8.8e-100
XP_016885066 (OMIM: 311790) 6-phosphofructo-2-kina ( 468) 1702 336.9 8.5e-92
NP_001304066 (OMIM: 605320) 6-phosphofructo-2-kina ( 434) 1522 302.4 2e-81
XP_016862104 (OMIM: 605320) 6-phosphofructo-2-kina ( 463) 1453 289.1 2e-77
NP_001304067 (OMIM: 605320) 6-phosphofructo-2-kina ( 278) 1404 279.6 9.2e-75
XP_005273219 (OMIM: 171835) 6-phosphofructo-2-kina ( 263) 1193 239.1 1.4e-62
>>NP_004557 (OMIM: 605319) 6-phosphofructo-2-kinase/fruc (520 aa)
initn: 3488 init1: 3488 opt: 3488 Z-score: 3621.3 bits: 679.7 E(93482): 6.3e-195
Smith-Waterman score: 3488; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
430 440 450 460 470 480
490 500 510 520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
::::::::::::::::::::::::::::::::::::::::
NP_004 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
490 500 510 520
>>NP_001350474 (OMIM: 605319) 6-phosphofructo-2-kinase/f (568 aa)
initn: 3428 init1: 3401 opt: 3402 Z-score: 3531.5 bits: 663.2 E(93482): 6.3e-190
Smith-Waterman score: 3402; 98.4% identity (99.4% similar) in 515 aa overlap (1-515:1-515)
10 20 30 40 50 60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
430 440 450 460 470 480
490 500 510 520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
:::::::::::::::::::::::::..:.. . :
NP_001 EHVASTSAALPSCLPPEVPTQLPGQELKSGIPGRDPEPPVQPPEGQSILWIPREVTVASR
490 500 510 520 530 540
NP_001 SGPGAAPSIPEPRLVSLPHLSGSAASGS
550 560
>>NP_001300992 (OMIM: 605319) 6-phosphofructo-2-kinase/f (514 aa)
initn: 3425 init1: 3398 opt: 3398 Z-score: 3528.0 bits: 662.4 E(93482): 9.8e-190
Smith-Waterman score: 3398; 99.4% identity (99.6% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
430 440 450 460 470 480
490 500 510 520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
::::::::::::::::::::::::: . :
NP_001 EHVASTSAALPSCLPPEVPTQLPGQPLLGQACLT
490 500 510
>>NP_001138915 (OMIM: 605319) 6-phosphofructo-2-kinase/f (500 aa)
initn: 3310 init1: 3310 opt: 3310 Z-score: 3436.9 bits: 645.5 E(93482): 1.2e-184
Smith-Waterman score: 3310; 99.6% identity (100.0% similar) in 496 aa overlap (25-520:5-500)
10 20 30 40 50 60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
..::::::::::::::::::::::::::::::::::
NP_001 MPFRKACGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
10 20 30 40
70 80 90 100 110 120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
410 420 430 440 450 460
490 500 510 520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
::::::::::::::::::::::::::::::::::::::::
NP_001 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
470 480 490 500
>>NP_001269559 (OMIM: 605319) 6-phosphofructo-2-kinase/f (534 aa)
initn: 3307 init1: 3307 opt: 3309 Z-score: 3435.5 bits: 645.3 E(93482): 1.4e-184
Smith-Waterman score: 3309; 99.2% identity (99.6% similar) in 499 aa overlap (22-520:36-534)
10 20 30 40 50
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYI
:. .:::::::::::::::::::::::::
NP_001 QKEGDSQQAGALPLLCQLDTFSPKATVFGVSINPACGPKLTNSPTVIVMVGLPARGKTYI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 SKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 SYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKIS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 SPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 QSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 KDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 KYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLK
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 CPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPT
430 440 450 460 470 480
480 490 500 510 520
pF1KE3 KKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
490 500 510 520 530
>>XP_016871816 (OMIM: 605319) 6-phosphofructo-2-kinase/f (548 aa)
initn: 3246 init1: 3219 opt: 3224 Z-score: 3347.2 bits: 629.0 E(93482): 1.2e-179
Smith-Waterman score: 3224; 98.0% identity (99.4% similar) in 491 aa overlap (25-515:5-495)
10 20 30 40 50 60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
..::::::::::::::::::::::::::::::::::
XP_016 MPFRKACGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
10 20 30 40
70 80 90 100 110 120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
410 420 430 440 450 460
490 500 510 520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
:::::::::::::::::::::::::..:.. . :
XP_016 EHVASTSAALPSCLPPEVPTQLPGQELKSGIPGRDPEPPVQPPEGQSILWIPREVTVASR
470 480 490 500 510 520
XP_016 SGPGAAPSIPEPRLVSLPHLSGSAASGS
530 540
>>NP_001309945 (OMIM: 605319) 6-phosphofructo-2-kinase/f (494 aa)
initn: 3243 init1: 3216 opt: 3220 Z-score: 3343.7 bits: 628.2 E(93482): 1.8e-179
Smith-Waterman score: 3220; 99.0% identity (99.6% similar) in 485 aa overlap (25-509:5-489)
10 20 30 40 50 60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
..::::::::::::::::::::::::::::::::::
NP_001 MPFRKACGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
10 20 30 40
70 80 90 100 110 120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
410 420 430 440 450 460
490 500 510 520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
::::::::::::::::::::::::: . :
NP_001 EHVASTSAALPSCLPPEVPTQLPGQPLLGQACLT
470 480 490
>>XP_005252521 (OMIM: 605319) 6-phosphofructo-2-kinase/f (462 aa)
initn: 3030 init1: 3003 opt: 3003 Z-score: 3119.0 bits: 586.6 E(93482): 5.9e-167
Smith-Waterman score: 3003; 99.6% identity (99.8% similar) in 450 aa overlap (1-450:1-450)
10 20 30 40 50 60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
:::::::::::::::::::::::::::. :
XP_005 TPVAYGCRVESIYLNVESVCTHRERSENMKGSRSSADSSRKH
430 440 450 460
>>XP_016871818 (OMIM: 605319) 6-phosphofructo-2-kinase/f (501 aa)
initn: 2382 init1: 2382 opt: 2382 Z-score: 2474.5 bits: 467.4 E(93482): 4.7e-131
Smith-Waterman score: 3315; 96.3% identity (96.3% similar) in 520 aa overlap (1-520:1-501)
10 20 30 40 50 60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
::::::::::::::::::::::::::: ::::::::::::::
XP_016 IAVFDATNTTRERRHMILHFAKENDFK-------------------EVKISSPDYKDCNS
130 140 150 160
190 200 210 220 230 240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
410 420 430 440 450 460
490 500 510 520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
::::::::::::::::::::::::::::::::::::::::
XP_016 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
470 480 490 500
>>XP_016871815 (OMIM: 605319) 6-phosphofructo-2-kinase/f (549 aa)
initn: 3265 init1: 2294 opt: 2296 Z-score: 2384.7 bits: 451.0 E(93482): 4.7e-126
Smith-Waterman score: 3229; 94.8% identity (95.7% similar) in 515 aa overlap (1-515:1-496)
10 20 30 40 50 60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
::::::::::::::::::::::::::: ::::::::::::::
XP_016 IAVFDATNTTRERRHMILHFAKENDFK-------------------EVKISSPDYKDCNS
130 140 150 160
190 200 210 220 230 240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
410 420 430 440 450 460
490 500 510 520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
:::::::::::::::::::::::::..:.. . :
XP_016 EHVASTSAALPSCLPPEVPTQLPGQELKSGIPGRDPEPPVQPPEGQSILWIPREVTVASR
470 480 490 500 510 520
XP_016 SGPGAAPSIPEPRLVSLPHLSGSAASGS
530 540
520 residues in 1 query sequences
65951994 residues in 93482 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Jun 19 14:28:11 2019 done: Wed Jun 19 14:28:12 2019
Total Scan time: 4.880 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]