Result of FASTA (ccds) for
pF1KE3269
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3269, 670 aa
1>>>pF1KE3269 670 - 670 aa - 670 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5366+/-0.00125; mu= 5.3520+/- 0.074
mean_var=238.1766+/-51.516, 0's: 0 Z-trim(108.9): 97 B-trim: 86 in 1/50
Lambda= 0.083105
statistics sampled from 10455 (10541) to 10455 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.324), width: 16
Scan time: 3.300
The best scores are: opt bits E(32554)
CCDS10461.1 TRAF7 gene_id:84231|Hs108|chr16 ( 670) 4569 561.7 1.2e-159
CCDS34078.1 FBXW7 gene_id:55294|Hs108|chr4 ( 589) 487 72.3 2.3e-12
CCDS3778.1 FBXW7 gene_id:55294|Hs108|chr4 ( 627) 487 72.3 2.4e-12
CCDS3777.1 FBXW7 gene_id:55294|Hs108|chr4 ( 707) 487 72.3 2.6e-12
>>CCDS10461.1 TRAF7 gene_id:84231|Hs108|chr16 (670 aa)
initn: 4569 init1: 4569 opt: 4569 Z-score: 2979.9 bits: 561.7 E(32554): 1.2e-159
Smith-Waterman score: 4569; 100.0% identity (100.0% similar) in 670 aa overlap (1-670:1-670)
10 20 30 40 50 60
pF1KE3 MSSGKSARYNRFSGGPSNLPTPDVTTGTRMETTFGPAFSAVTTITKADGTSTYKQHCRTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MSSGKSARYNRFSGGPSNLPTPDVTTGTRMETTFGPAFSAVTTITKADGTSTYKQHCRTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SSSSTLAYSPRDEEDSMPPISTPRRSDSAISVRSLHSESSMSLRSTFSLPEEEEEPEPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SSSSTLAYSPRDEEDSMPPISTPRRSDSAISVRSLHSESSMSLRSTFSLPEEEEEPEPLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRCALKSEKCPVDNVKLTVVVNNIAVAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRCALKSEKCPVDNVKLTVVVNNIAVAEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IGELFIHCRHGCRVAGSGKPPIFEVDPRGCPFTIKLSARKDHEGSCDYRPVRCPNNPSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 IGELFIHCRHGCRVAGSGKPPIFEVDPRGCPFTIKLSARKDHEGSCDYRPVRCPNNPSCP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PLLRMNLEAHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PLLRMNLEAHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 MHVALAQKDQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MHVALAQKDQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LNDELSHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LNDELSHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PVCTLVSSHNVLFSGSLKAIKVWDIVGTELKLKKELTGLNHWVRALVAAQSYLYSGSYQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PVCTLVSSHNVLFSGSLKAIKVWDIVGTELKLKKELTGLNHWVRALVAAQSYLYSGSYQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 IKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIESKEQVRTLTGHVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 IKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIESKEQVRTLTGHVG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSRGRLFSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSRGRLFSGA
610 620 630 640 650 660
670
pF1KE3 VDSTVKVWTC
::::::::::
CCDS10 VDSTVKVWTC
670
>>CCDS34078.1 FBXW7 gene_id:55294|Hs108|chr4 (589 aa)
initn: 358 init1: 252 opt: 487 Z-score: 335.6 bits: 72.3 E(32554): 2.3e-12
Smith-Waterman score: 491; 28.7% identity (58.0% similar) in 414 aa overlap (279-668:139-531)
250 260 270 280 290 300
pF1KE3 AHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQK
...:. .:...: . .:.. ..: :
CCDS34 SVQPPTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPK
110 120 130 140 150 160
310 320 330 340 350 360
pF1KE3 DQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASMLN-DELSH
. . .. :.: : : :. . .. :.:: . .:. . . :: :
CCDS34 ELAL-YVLSFL----EPKDLLQAAQTCRY------WRILAEDNLLWREKCKEEGIDEPLH
170 180 190 200 210
370 380 390 400 410
pF1KE3 INAR--LNMGILGS-----YDPQQI---------FKCKGTFVGHQGPVWCLCVYSMGDLL
:. : .. :.. : : :. .: .. ::. : :. :. .
CCDS34 IKRRKVIKPGFIHSPWKSAYIRQHRIDTNWRRGELKSPKVLKGHDDHV-ITCLQFCGNRI
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE3 FSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQK
:::.:.:.::: . .: :: .:: :: : : . .. . :::.: :. ::. .. .
CCDS34 VSGSDDNTLKVW-SAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGEC
280 290 300 310 320 330
480 490 500 510 520
pF1KE3 VNTIRAHDNPV-CTLVSSHNVLFSGSLKA-IKVWDI-VGTELKLKKELTGLNHWVRALVA
..:. .: . : : . . :. ::: : ..:::: .: :.. : : :: .
CCDS34 IHTLYGHTSTVRCMHLHEKRVV-SGSRDATLRVWDIETGQCLHV---LMGHVAAVRCVQY
340 350 360 370 380 390
530 540 550 560 570 580
pF1KE3 AQSYLYSGSYQ-TIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIE
. ::.:. .:.:: .: :.:.:: . :::. . :.: :. .. :.:::.:
CCDS34 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVE
400 410 420 430 440 450
590 600 610 620 630 640
pF1KE3 SKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLL---RHQG
. . ..::::: . . .. . :. : :.. : ....:.. . : ::: .::.
CCDS34 TGNCIHTLTGHQSLTSGMEL---KDNILV-SGNADSTVKIWDIKTGQCLQTLQGPNKHQS
460 470 480 490 500
650 660 670
pF1KE3 SVTALAVSRGRLFSGAVDSTVKVWTC
.:: : ... ..... :.:::.:
CCDS34 AVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCA
510 520 530 540 550 560
>>CCDS3778.1 FBXW7 gene_id:55294|Hs108|chr4 (627 aa)
initn: 358 init1: 252 opt: 487 Z-score: 335.3 bits: 72.3 E(32554): 2.4e-12
Smith-Waterman score: 491; 28.7% identity (58.0% similar) in 414 aa overlap (279-668:177-569)
250 260 270 280 290 300
pF1KE3 AHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQK
...:. .:...: . .:.. ..: :
CCDS37 SVQPPTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPK
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE3 DQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASMLN-DELSH
. . .. :.: : : :. . .. :.:: . .:. . . :: :
CCDS37 ELAL-YVLSFL----EPKDLLQAAQTCRY------WRILAEDNLLWREKCKEEGIDEPLH
210 220 230 240 250
370 380 390 400 410
pF1KE3 INAR--LNMGILGS-----YDPQQI---------FKCKGTFVGHQGPVWCLCVYSMGDLL
:. : .. :.. : : :. .: .. ::. : :. :. .
CCDS37 IKRRKVIKPGFIHSPWKSAYIRQHRIDTNWRRGELKSPKVLKGHDDHV-ITCLQFCGNRI
260 270 280 290 300 310
420 430 440 450 460 470
pF1KE3 FSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQK
:::.:.:.::: . .: :: .:: :: : : . .. . :::.: :. ::. .. .
CCDS37 VSGSDDNTLKVW-SAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGEC
320 330 340 350 360 370
480 490 500 510 520
pF1KE3 VNTIRAHDNPV-CTLVSSHNVLFSGSLKA-IKVWDI-VGTELKLKKELTGLNHWVRALVA
..:. .: . : : . . :. ::: : ..:::: .: :.. : : :: .
CCDS37 IHTLYGHTSTVRCMHLHEKRVV-SGSRDATLRVWDIETGQCLHV---LMGHVAAVRCVQY
380 390 400 410 420
530 540 550 560 570 580
pF1KE3 AQSYLYSGSYQ-TIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIE
. ::.:. .:.:: .: :.:.:: . :::. . :.: :. .. :.:::.:
CCDS37 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVE
430 440 450 460 470 480
590 600 610 620 630 640
pF1KE3 SKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLL---RHQG
. . ..::::: . . .. . :. : :.. : ....:.. . : ::: .::.
CCDS37 TGNCIHTLTGHQSLTSGMEL---KDNILV-SGNADSTVKIWDIKTGQCLQTLQGPNKHQS
490 500 510 520 530 540
650 660 670
pF1KE3 SVTALAVSRGRLFSGAVDSTVKVWTC
.:: : ... ..... :.:::.:
CCDS37 AVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCA
550 560 570 580 590 600
>>CCDS3777.1 FBXW7 gene_id:55294|Hs108|chr4 (707 aa)
initn: 358 init1: 252 opt: 487 Z-score: 334.6 bits: 72.3 E(32554): 2.6e-12
Smith-Waterman score: 491; 28.7% identity (58.0% similar) in 414 aa overlap (279-668:257-649)
250 260 270 280 290 300
pF1KE3 AHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQK
...:. .:...: . .:.. ..: :
CCDS37 SVQPPTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPK
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 DQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASMLN-DELSH
. . .. :.: : : :. . .. :.:: . .:. . . :: :
CCDS37 ELAL-YVLSFL----EPKDLLQAAQTCRY------WRILAEDNLLWREKCKEEGIDEPLH
290 300 310 320 330
370 380 390 400 410
pF1KE3 INAR--LNMGILGS-----YDPQQI---------FKCKGTFVGHQGPVWCLCVYSMGDLL
:. : .. :.. : : :. .: .. ::. : :. :. .
CCDS37 IKRRKVIKPGFIHSPWKSAYIRQHRIDTNWRRGELKSPKVLKGHDDHV-ITCLQFCGNRI
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE3 FSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQK
:::.:.:.::: . .: :: .:: :: : : . .. . :::.: :. ::. .. .
CCDS37 VSGSDDNTLKVW-SAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGEC
400 410 420 430 440 450
480 490 500 510 520
pF1KE3 VNTIRAHDNPV-CTLVSSHNVLFSGSLKA-IKVWDI-VGTELKLKKELTGLNHWVRALVA
..:. .: . : : . . :. ::: : ..:::: .: :.. : : :: .
CCDS37 IHTLYGHTSTVRCMHLHEKRVV-SGSRDATLRVWDIETGQCLHV---LMGHVAAVRCVQY
460 470 480 490 500
530 540 550 560 570 580
pF1KE3 AQSYLYSGSYQ-TIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIE
. ::.:. .:.:: .: :.:.:: . :::. . :.: :. .. :.:::.:
CCDS37 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVE
510 520 530 540 550 560
590 600 610 620 630 640
pF1KE3 SKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLL---RHQG
. . ..::::: . . .. . :. : :.. : ....:.. . : ::: .::.
CCDS37 TGNCIHTLTGHQSLTSGMEL---KDNILV-SGNADSTVKIWDIKTGQCLQTLQGPNKHQS
570 580 590 600 610 620
650 660 670
pF1KE3 SVTALAVSRGRLFSGAVDSTVKVWTC
.:: : ... ..... :.:::.:
CCDS37 AVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCA
630 640 650 660 670 680
670 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Feb 10 15:02:35 2017 done: Fri Feb 10 15:02:36 2017
Total Scan time: 3.300 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]