Result of FASTA (omim) for
pF1KE3316
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3316, 878 aa
1>>>pF1KE3316 878 - 878 aa - 878 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.7082+/-0.000464; mu= -2.2159+/- 0.029
mean_var=520.4380+/-113.187, 0's: 0 Z-trim(122.3): 1757 B-trim: 0 in 0/51
Lambda= 0.056220
statistics sampled from 37948 (40271) to 37948 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.472), width: 16
Scan time: 15.020
The best scores are: opt bits E(85289)
NP_001073350 (OMIM: 607074) serine/threonine-prote ( 878) 5958 499.0 4e-140
NP_001073349 (OMIM: 607074) serine/threonine-prote ( 878) 5958 499.0 4e-140
NP_057541 (OMIM: 607074) serine/threonine-protein ( 878) 5958 499.0 4e-140
XP_005258773 (OMIM: 607074) PREDICTED: serine/thre ( 721) 4872 410.8 1.2e-113
NP_001073351 (OMIM: 607074) serine/threonine-prote ( 721) 4872 410.8 1.2e-113
XP_016876951 (OMIM: 605435) PREDICTED: serine/thre ( 747) 2605 227.0 2.7e-58
XP_011535267 (OMIM: 605435) PREDICTED: serine/thre ( 824) 2605 227.0 2.8e-58
XP_016876950 (OMIM: 605435) PREDICTED: serine/thre ( 824) 2605 227.0 2.8e-58
XP_011535266 (OMIM: 605435) PREDICTED: serine/thre ( 844) 2605 227.0 2.9e-58
NP_002733 (OMIM: 605435) serine/threonine-protein ( 912) 2605 227.1 3e-58
NP_001316998 (OMIM: 605435) serine/threonine-prote ( 920) 2605 227.1 3e-58
XP_016859232 (OMIM: 607077) PREDICTED: serine/thre ( 631) 2516 219.6 3.6e-56
XP_016859233 (OMIM: 607077) PREDICTED: serine/thre ( 631) 2516 219.6 3.6e-56
XP_016859230 (OMIM: 607077) PREDICTED: serine/thre ( 717) 2516 219.7 3.9e-56
XP_016859231 (OMIM: 607077) PREDICTED: serine/thre ( 717) 2516 219.7 3.9e-56
XP_005264295 (OMIM: 607077) PREDICTED: serine/thre ( 786) 2516 219.8 4.1e-56
NP_005804 (OMIM: 607077) serine/threonine-protein ( 890) 2516 219.8 4.4e-56
XP_005264294 (OMIM: 607077) PREDICTED: serine/thre ( 890) 2516 219.8 4.4e-56
XP_016884050 (OMIM: 114480,176807,259500,604373,60 ( 322) 628 66.1 3e-10
NP_001244316 (OMIM: 114480,176807,259500,604373,60 ( 322) 628 66.1 3e-10
XP_011528147 (OMIM: 114480,176807,259500,604373,60 ( 322) 628 66.1 3e-10
NP_009125 (OMIM: 114480,176807,259500,604373,60926 ( 543) 628 66.4 4.1e-10
XP_016884049 (OMIM: 114480,176807,259500,604373,60 ( 584) 628 66.5 4.3e-10
NP_001005735 (OMIM: 114480,176807,259500,604373,60 ( 586) 628 66.5 4.3e-10
XP_011528141 (OMIM: 114480,176807,259500,604373,60 ( 596) 628 66.5 4.3e-10
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355) 616 65.2 6.2e-10
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357) 616 65.2 6.3e-10
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362) 616 65.2 6.3e-10
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385) 616 65.3 6.6e-10
XP_006724179 (OMIM: 114480,176807,259500,604373,60 ( 362) 614 65.1 7.1e-10
XP_011528145 (OMIM: 114480,176807,259500,604373,60 ( 476) 615 65.3 7.9e-10
XP_011528144 (OMIM: 114480,176807,259500,604373,60 ( 486) 615 65.3 8e-10
XP_011528143 (OMIM: 114480,176807,259500,604373,60 ( 519) 615 65.3 8.3e-10
XP_006724177 (OMIM: 114480,176807,259500,604373,60 ( 394) 609 64.7 9.8e-10
XP_011532469 (OMIM: 613167) PREDICTED: serine/thre ( 648) 610 65.1 1.3e-09
NP_208382 (OMIM: 613167) serine/threonine-protein ( 648) 610 65.1 1.3e-09
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 603 64.2 1.3e-09
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413) 603 64.2 1.4e-09
XP_006717544 (OMIM: 607957) PREDICTED: calcium/cal ( 366) 589 63.0 2.9e-09
XP_016863321 (OMIM: 613166) PREDICTED: serine/thre ( 717) 595 63.9 3.1e-09
XP_005262843 (OMIM: 613166) PREDICTED: serine/thre ( 765) 595 63.9 3.2e-09
NP_001035350 (OMIM: 613166) serine/threonine-prote ( 766) 595 63.9 3.2e-09
XP_005262842 (OMIM: 613166) PREDICTED: serine/thre ( 782) 595 64.0 3.3e-09
NP_001035351 (OMIM: 613166) serine/threonine-prote ( 783) 595 64.0 3.3e-09
XP_011517893 (OMIM: 607957) PREDICTED: calcium/cal ( 372) 587 62.9 3.3e-09
NP_065172 (OMIM: 614994) calcium/calmodulin-depend ( 476) 586 62.9 4e-09
XP_016857355 (OMIM: 614994) PREDICTED: calcium/cal ( 476) 586 62.9 4e-09
XP_016884766 (OMIM: 300680) PREDICTED: calcium/cal ( 426) 567 61.3 1.1e-08
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426) 567 61.3 1.1e-08
XP_016884768 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 562 60.8 1.3e-08
>>NP_001073350 (OMIM: 607074) serine/threonine-protein k (878 aa)
initn: 5958 init1: 5958 opt: 5958 Z-score: 2636.7 bits: 499.0 E(85289): 4e-140
Smith-Waterman score: 5958; 100.0% identity (100.0% similar) in 878 aa overlap (1-878:1-878)
10 20 30 40 50 60
pF1KE3 MATAPSYPAGLPGSPGPGSPPPPGGLELQSPPPLLPQIPAPGSGVSFHIQIGLTREFVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATAPSYPAGLPGSPGPGSPPPPGGLELQSPPPLLPQIPAPGSGVSFHIQIGLTREFVLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 NCHKRCATRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCHKRCATRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 MPGGTPGGPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGTPGGPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 ENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 EVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 IDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQF
790 800 810 820 830 840
850 860 870
pF1KE3 AAEHPLPGSGLPTDRDLGGACPPQDHDMQGLAERISVL
::::::::::::::::::::::::::::::::::::::
NP_001 AAEHPLPGSGLPTDRDLGGACPPQDHDMQGLAERISVL
850 860 870
>>NP_001073349 (OMIM: 607074) serine/threonine-protein k (878 aa)
initn: 5958 init1: 5958 opt: 5958 Z-score: 2636.7 bits: 499.0 E(85289): 4e-140
Smith-Waterman score: 5958; 100.0% identity (100.0% similar) in 878 aa overlap (1-878:1-878)
10 20 30 40 50 60
pF1KE3 MATAPSYPAGLPGSPGPGSPPPPGGLELQSPPPLLPQIPAPGSGVSFHIQIGLTREFVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATAPSYPAGLPGSPGPGSPPPPGGLELQSPPPLLPQIPAPGSGVSFHIQIGLTREFVLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 NCHKRCATRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCHKRCATRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 MPGGTPGGPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGTPGGPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 ENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 EVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 IDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQF
790 800 810 820 830 840
850 860 870
pF1KE3 AAEHPLPGSGLPTDRDLGGACPPQDHDMQGLAERISVL
::::::::::::::::::::::::::::::::::::::
NP_001 AAEHPLPGSGLPTDRDLGGACPPQDHDMQGLAERISVL
850 860 870
>>NP_057541 (OMIM: 607074) serine/threonine-protein kina (878 aa)
initn: 5958 init1: 5958 opt: 5958 Z-score: 2636.7 bits: 499.0 E(85289): 4e-140
Smith-Waterman score: 5958; 100.0% identity (100.0% similar) in 878 aa overlap (1-878:1-878)
10 20 30 40 50 60
pF1KE3 MATAPSYPAGLPGSPGPGSPPPPGGLELQSPPPLLPQIPAPGSGVSFHIQIGLTREFVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MATAPSYPAGLPGSPGPGSPPPPGGLELQSPPPLLPQIPAPGSGVSFHIQIGLTREFVLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEGDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 NCHKRCATRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NCHKRCATRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ASEEEEGEGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 MPGGTPGGPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MPGGTPGGPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 ENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 EVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 IDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQF
790 800 810 820 830 840
850 860 870
pF1KE3 AAEHPLPGSGLPTDRDLGGACPPQDHDMQGLAERISVL
::::::::::::::::::::::::::::::::::::::
NP_057 AAEHPLPGSGLPTDRDLGGACPPQDHDMQGLAERISVL
850 860 870
>>XP_005258773 (OMIM: 607074) PREDICTED: serine/threonin (721 aa)
initn: 4872 init1: 4872 opt: 4872 Z-score: 2161.5 bits: 410.8 E(85289): 1.2e-113
Smith-Waterman score: 4872; 100.0% identity (100.0% similar) in 721 aa overlap (158-878:1-721)
130 140 150 160 170 180
pF1KE3 SATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNN
::::::::::::::::::::::::::::::
XP_005 MLFGLVRQGLKCDGCGLNYHKRCAFSIPNN
10 20 30
190 200 210 220 230 240
pF1KE3 CSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSSSSASSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSSSSASSYT
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE3 GRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCA
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE3 TRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALHASEEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALHASEEEEG
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE3 EGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCIT
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE3 LFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGEMPGGTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGEMPGGTPG
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE3 GPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIAT
340 350 360 370 380 390
550 560 570 580 590 600
pF1KE3 VYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRH
400 410 420 430 440 450
610 620 630 640 650 660
pF1KE3 PGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHF
460 470 480 490 500 510
670 680 690 700 710 720
pF1KE3 KNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQG
520 530 540 550 560 570
730 740 750 760 770 780
pF1KE3 YNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNL
580 590 600 610 620 630
790 800 810 820 830 840
pF1KE3 LQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPLP
640 650 660 670 680 690
850 860 870
pF1KE3 GSGLPTDRDLGGACPPQDHDMQGLAERISVL
:::::::::::::::::::::::::::::::
XP_005 GSGLPTDRDLGGACPPQDHDMQGLAERISVL
700 710 720
>>NP_001073351 (OMIM: 607074) serine/threonine-protein k (721 aa)
initn: 4872 init1: 4872 opt: 4872 Z-score: 2161.5 bits: 410.8 E(85289): 1.2e-113
Smith-Waterman score: 4872; 100.0% identity (100.0% similar) in 721 aa overlap (158-878:1-721)
130 140 150 160 170 180
pF1KE3 SATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNN
::::::::::::::::::::::::::::::
NP_001 MLFGLVRQGLKCDGCGLNYHKRCAFSIPNN
10 20 30
190 200 210 220 230 240
pF1KE3 CSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSSSSASSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSGARKRRLSSTSLASGHSVRLGTSESLPCTAEELSRSTTELLPRRPPSSSSSSSASSYT
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE3 GRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCA
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE3 TRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALHASEEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRVPNDCLGEALINGDVPMEEATDFSEADKSALMDESEDSGVIPGSHSENALHASEEEEG
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE3 EGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGGKAQSSLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCIT
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE3 LFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGEMPGGTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGEMPGGTPG
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE3 GPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIAT
340 350 360 370 380 390
550 560 570 580 590 600
pF1KE3 VYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRH
400 410 420 430 440 450
610 620 630 640 650 660
pF1KE3 PGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHF
460 470 480 490 500 510
670 680 690 700 710 720
pF1KE3 KNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQG
520 530 540 550 560 570
730 740 750 760 770 780
pF1KE3 YNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNL
580 590 600 610 620 630
790 800 810 820 830 840
pF1KE3 LQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPLP
640 650 660 670 680 690
850 860 870
pF1KE3 GSGLPTDRDLGGACPPQDHDMQGLAERISVL
:::::::::::::::::::::::::::::::
NP_001 GSGLPTDRDLGGACPPQDHDMQGLAERISVL
700 710 720
>>XP_016876951 (OMIM: 605435) PREDICTED: serine/threonin (747 aa)
initn: 3360 init1: 2056 opt: 2605 Z-score: 1167.7 bits: 227.0 E(85289): 2.7e-58
Smith-Waterman score: 3390; 68.7% identity (84.7% similar) in 754 aa overlap (158-878:1-747)
130 140 150 160 170 180
pF1KE3 SATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNN
::.:::::::::.::::::::::::.::::
XP_016 MLWGLVRQGLKCEGCGLNYHKRCAFKIPNN
10 20 30
190 200 210 220 230 240
pF1KE3 CSGARKRRLSSTSLASGHSVRLGTSESLPCTAEE--LSRSTTELLPRRPPSSSSSSSASS
:::.:.::::..::.. ..: ...: . .: :..: .: . : :.:.:
XP_016 CSGVRRRRLSNVSLTGVSTIRTSSAELSTSAPDEPLLQKSPSESFIGREKRSNSQS----
40 50 60 70 80
250 260 270 280 290 300
pF1KE3 YTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQGLQCKDCKFNCHKR
: ::::.:::.:.:::::::::.::::::::::: ::::::::::::::::::.::::::
XP_016 YIGRPIHLDKILMSKVKVPHTFVIHSYTRPTVCQYCKKLLKGLFRQGLQCKDCRFNCHKR
90 100 110 120 130 140
310 320 330 340 350
pF1KE3 CATRVPNDCLGEALINGD---------VPMEEATDFSEADK-SALMDESEDSGVIPGSHS
:: .:::.::::. :::: : :::..: ..... :.:::. :.. : . .
XP_016 CAPKVPNNCLGEVTINGDLLSPGAESDVVMEEGSDDNDSERNSGLMDDMEEAMV---QDA
150 160 170 180 190 200
360 370 380 390 400
pF1KE3 ENALHASEEEEGEGGK------------AQSSLGYIPLMRVVQSVRHTTRKSSTTLREGW
: :. ... :: . :. . ::::::::::.:: :::::...:::
XP_016 EMAMAECQNDSGEMQDPDPDHEDANRTISPSTSNNIPLMRVVQSVKHTKRKSSTVMKEGW
210 220 230 240 250 260
410 420 430 440 450 460
pF1KE3 VVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILTVESAQNFSLVPPGTN
.:::..::::::::::::: ::::::::.: .::::::::::::..: ... .:.: :.:
XP_016 MVHYTSKDTLRKRHYWRLDSKCITLFQNDTGSRYYKEIPLSEILSLEPVKTSALIPNGAN
270 280 290 300 310 320
470 480 490 500 510
pF1KE3 PHCFEIVTANATYFVGEM---PGG-TPGGP---SGQGAEAARGWETAIRQALMPVILQDA
::::::.:::..:.::: :.. .:.. :: ::..:: :: ::..:::::: . .
XP_016 PHCFEITTANVVYYVGENVVNPSSPSPNNSVLTSGVGADVARMWEIAIQHALMPVIPKGS
330 340 350 360 370 380
520 530 540 550 560 570
pF1KE3 PSAPGHAPHRQASLSISVSNSQIQENVDIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRD
. : ::. :.:::::: ::::::::.:::::::::::::::::.::::::::::::
XP_016 SVGTGTNLHRDISVSISVSNCQIQENVDISTVYQIFPDEVLGSGQFGIVYGGKHRKTGRD
390 400 410 420 430 440
580 590 600 610 620 630
pF1KE3 VAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKVFVVMEKLHGDMLE
::.:.::::::::::::::::::::::.:.:::.:::::::::::.::::::::::::::
XP_016 VAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLECMFETPERVFVVMEKLHGDMLE
450 460 470 480 490 500
640 650 660 670 680 690
pF1KE3 MILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDF
::::::::::::..::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDF
510 520 530 540 550 560
700 710 720 730 740 750
pF1KE3 GFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPFNEDED
::::::::::::::::::::::::::: :.::::::::::::::.:::::::::::::::
XP_016 GFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFNEDED
570 580 590 600 610 620
760 770 780 790 800 810
pF1KE3 INDQIQNAAFMYPASPWSHISAGAIDLINNLLQVKMRKRYSVDKSLSHPWLQEYQTWLDL
:.::::::::::: .::..:: :::::::::::::::::::::.:::::::.:::::::
XP_016 IHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPWLQDYQTWLDL
630 640 650 660 670 680
820 830 840 850 860 870
pF1KE3 RELEGKMGERYITHESDDARWEQFAAEHPL--PGSGLPTDRDLGGACPPQDHDMQGLAER
:::: :.::::::::::: :::..:.:. : : . . . . . .. .:..:.::
XP_016 RELECKIGERYITHESDDLRWEKYAGEQGLQYPTHLINPSASHSDTPETEETEMKALGER
690 700 710 720 730 740
pF1KE3 ISVL
.:.:
XP_016 VSIL
>>XP_011535267 (OMIM: 605435) PREDICTED: serine/threonin (824 aa)
initn: 3763 init1: 2056 opt: 2605 Z-score: 1167.2 bits: 227.0 E(85289): 2.8e-58
Smith-Waterman score: 3812; 69.8% identity (85.5% similar) in 827 aa overlap (89-878:1-824)
60 70 80 90 100 110
pF1KE3 LLPAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEG
.:::::::.::::: :.::::....:::::
XP_011 MYDKILLFRHDPTSENILQLVKAASDIQEG
10 20 30
120 130 140 150 160 170
pF1KE3 DLVEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHK
::.:::::::::::::::::::: :::::::::::::::::.:::::::::.::::::::
XP_011 DLIEVVLSASATFEDFQIRPHALFVHSYRAPAFCDHCGEMLWGLVRQGLKCEGCGLNYHK
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE3 RCAFSIPNNCSGARKRRLSSTSLASGHSVRLGTSE-SLPCTAEELSRSTTELLPRRPPSS
::::.:::::::.:.::::..::.. ..: ...: : : : .. . .. ::
XP_011 RCAFKIPNNCSGVRRRRLSNVSLTGVSTIRTSSAELSTSAPDEPLLSPVSPGFEQKSPSE
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE3 S-----SSSSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQG
: . :...:: ::::.:::.:.:::::::::.::::::::::: ::::::::::::
XP_011 SFIGREKRSNSQSYIGRPIHLDKILMSKVKVPHTFVIHSYTRPTVCQYCKKLLKGLFRQG
160 170 180 190 200 210
300 310 320 330 340
pF1KE3 LQCKDCKFNCHKRCATRVPNDCLGEALINGD---------VPMEEATDFSEADK-SALMD
::::::.:::::::: .:::.::::. :::: : :::..: ..... :.:::
XP_011 LQCKDCRFNCHKRCAPKVPNNCLGEVTINGDLLSPGAESDVVMEEGSDDNDSERNSGLMD
220 230 240 250 260 270
350 360 370 380 390
pF1KE3 ESEDSGVIPGSHSENALHASEEEEGEGGK------------AQSSLGYIPLMRVVQSVRH
. :.. : . .: :. ... :: . :. . ::::::::::.:
XP_011 DMEEAMV---QDAEMAMAECQNDSGEMQDPDPDHEDANRTISPSTSNNIPLMRVVQSVKH
280 290 300 310 320
400 410 420 430 440 450
pF1KE3 TTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILTVE
: :::::...:::.:::..::::::::::::: ::::::::.: .::::::::::::..:
XP_011 TKRKSSTVMKEGWMVHYTSKDTLRKRHYWRLDSKCITLFQNDTGSRYYKEIPLSEILSLE
330 340 350 360 370 380
460 470 480 490 500
pF1KE3 SAQNFSLVPPGTNPHCFEIVTANATYFVGEM---PGG-TPGGP---SGQGAEAARGWETA
... .:.: :.:::::::.:::..:.::: :.. .:.. :: ::..:: :: :
XP_011 PVKTSALIPNGANPHCFEITTANVVYYVGENVVNPSSPSPNNSVLTSGVGADVARMWEIA
390 400 410 420 430 440
510 520 530 540 550 560
pF1KE3 IRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIATVYQIFPDEVLGSGQFG
:..:::::: . . . : ::. :.:::::: ::::::::.:::::::::::::::::
XP_011 IQHALMPVIPKGSSVGTGTNLHRDISVSISVSNCQIQENVDISTVYQIFPDEVLGSGQFG
450 460 470 480 490 500
570 580 590 600 610 620
pF1KE3 VVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKV
.::::::::::::::.:.::::::::::::::::::::::.:.:::.:::::::::::.:
XP_011 IVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLECMFETPERV
510 520 530 540 550 560
630 640 650 660 670 680
pF1KE3 FVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLLA
:::::::::::::::::::::::::..:::::::::::::::::::::::::::::::::
XP_011 FVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLA
570 580 590 600 610 620
690 700 710 720 730 740
pF1KE3 SADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYV
:::::::::::::::::::::::::::::::::::::::: :.::::::::::::::.::
XP_011 SADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYV
630 640 650 660 670 680
750 760 770 780 790 800
pF1KE3 SLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNLLQVKMRKRYSVDKSLS
::::::::::::::.::::::::::: .::..:: :::::::::::::::::::::.::
XP_011 SLSGTFPFNEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLS
690 700 710 720 730 740
810 820 830 840 850 860
pF1KE3 HPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPL--PGSGLPTDRDLGGAC
:::::.::::::::::: :.::::::::::: :::..:.:. : : . . . . .
XP_011 HPWLQDYQTWLDLRELECKIGERYITHESDDLRWEKYAGEQGLQYPTHLINPSASHSDTP
750 760 770 780 790 800
870
pF1KE3 PPQDHDMQGLAERISVL
.. .:..:.::.:.:
XP_011 ETEETEMKALGERVSIL
810 820
>>XP_016876950 (OMIM: 605435) PREDICTED: serine/threonin (824 aa)
initn: 3763 init1: 2056 opt: 2605 Z-score: 1167.2 bits: 227.0 E(85289): 2.8e-58
Smith-Waterman score: 3812; 69.8% identity (85.5% similar) in 827 aa overlap (89-878:1-824)
60 70 80 90 100 110
pF1KE3 LLPAASELAHVKQLACSIVDQKFPECGFYGLYDKILLFKHDPTSANLLQLVRSSGDIQEG
.:::::::.::::: :.::::....:::::
XP_016 MYDKILLFRHDPTSENILQLVKAASDIQEG
10 20 30
120 130 140 150 160 170
pF1KE3 DLVEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGLVRQGLKCDGCGLNYHK
::.:::::::::::::::::::: :::::::::::::::::.:::::::::.::::::::
XP_016 DLIEVVLSASATFEDFQIRPHALFVHSYRAPAFCDHCGEMLWGLVRQGLKCEGCGLNYHK
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE3 RCAFSIPNNCSGARKRRLSSTSLASGHSVRLGTSE-SLPCTAEELSRSTTELLPRRPPSS
::::.:::::::.:.::::..::.. ..: ...: : : : .. . .. ::
XP_016 RCAFKIPNNCSGVRRRRLSNVSLTGVSTIRTSSAELSTSAPDEPLLSPVSPGFEQKSPSE
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE3 S-----SSSSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTVCQACKKLLKGLFRQG
: . :...:: ::::.:::.:.:::::::::.::::::::::: ::::::::::::
XP_016 SFIGREKRSNSQSYIGRPIHLDKILMSKVKVPHTFVIHSYTRPTVCQYCKKLLKGLFRQG
160 170 180 190 200 210
300 310 320 330 340
pF1KE3 LQCKDCKFNCHKRCATRVPNDCLGEALINGD---------VPMEEATDFSEADK-SALMD
::::::.:::::::: .:::.::::. :::: : :::..: ..... :.:::
XP_016 LQCKDCRFNCHKRCAPKVPNNCLGEVTINGDLLSPGAESDVVMEEGSDDNDSERNSGLMD
220 230 240 250 260 270
350 360 370 380 390
pF1KE3 ESEDSGVIPGSHSENALHASEEEEGEGGK------------AQSSLGYIPLMRVVQSVRH
. :.. : . .: :. ... :: . :. . ::::::::::.:
XP_016 DMEEAMV---QDAEMAMAECQNDSGEMQDPDPDHEDANRTISPSTSNNIPLMRVVQSVKH
280 290 300 310 320
400 410 420 430 440 450
pF1KE3 TTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTNRYYKEIPLSEILTVE
: :::::...:::.:::..::::::::::::: ::::::::.: .::::::::::::..:
XP_016 TKRKSSTVMKEGWMVHYTSKDTLRKRHYWRLDSKCITLFQNDTGSRYYKEIPLSEILSLE
330 340 350 360 370 380
460 470 480 490 500
pF1KE3 SAQNFSLVPPGTNPHCFEIVTANATYFVGEM---PGG-TPGGP---SGQGAEAARGWETA
... .:.: :.:::::::.:::..:.::: :.. .:.. :: ::..:: :: :
XP_016 PVKTSALIPNGANPHCFEITTANVVYYVGENVVNPSSPSPNNSVLTSGVGADVARMWEIA
390 400 410 420 430 440
510 520 530 540 550 560
pF1KE3 IRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIATVYQIFPDEVLGSGQFG
:..:::::: . . . : ::. :.:::::: ::::::::.:::::::::::::::::
XP_016 IQHALMPVIPKGSSVGTGTNLHRDISVSISVSNCQIQENVDISTVYQIFPDEVLGSGQFG
450 460 470 480 490 500
570 580 590 600 610 620
pF1KE3 VVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHPGIVNLECMFETPEKV
.::::::::::::::.:.::::::::::::::::::::::.:.:::.:::::::::::.:
XP_016 IVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLECMFETPERV
510 520 530 540 550 560
630 640 650 660 670 680
pF1KE3 FVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLLA
:::::::::::::::::::::::::..:::::::::::::::::::::::::::::::::
XP_016 FVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLA
570 580 590 600 610 620
690 700 710 720 730 740
pF1KE3 SADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYV
:::::::::::::::::::::::::::::::::::::::: :.::::::::::::::.::
XP_016 SADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYV
630 640 650 660 670 680
750 760 770 780 790 800
pF1KE3 SLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNLLQVKMRKRYSVDKSLS
::::::::::::::.::::::::::: .::..:: :::::::::::::::::::::.::
XP_016 SLSGTFPFNEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLS
690 700 710 720 730 740
810 820 830 840 850 860
pF1KE3 HPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPL--PGSGLPTDRDLGGAC
:::::.::::::::::: :.::::::::::: :::..:.:. : : . . . . .
XP_016 HPWLQDYQTWLDLRELECKIGERYITHESDDLRWEKYAGEQGLQYPTHLINPSASHSDTP
750 760 770 780 790 800
870
pF1KE3 PPQDHDMQGLAERISVL
.. .:..:.::.:.:
XP_016 ETEETEMKALGERVSIL
810 820
>>XP_011535266 (OMIM: 605435) PREDICTED: serine/threonin (844 aa)
initn: 3832 init1: 2056 opt: 2605 Z-score: 1167.1 bits: 227.0 E(85289): 2.9e-58
Smith-Waterman score: 3886; 69.6% identity (85.5% similar) in 843 aa overlap (75-878:5-844)
50 60 70 80 90 100
pF1KE3 VSFHIQIGLTREFVLLPAASELAHVKQLACSIVDQK--FPECGFYGLYDKILLFKHDPTS
:.:... ::::::::.:::::::.:::::
XP_011 MWPPSVVEEEIMFPECGFYGMYDKILLFRHDPTS
10 20 30
110 120 130 140 150 160
pF1KE3 ANLLQLVRSSGDIQEGDLVEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEMLFGL
:.::::....:::::::.:::::::::::::::::::: :::::::::::::::::.::
XP_011 ENILQLVKAASDIQEGDLIEVVLSASATFEDFQIRPHALFVHSYRAPAFCDHCGEMLWGL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 VRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSSTSLASGHSVRLGTSE-SLPCTAEE
:::::::.::::::::::::.:::::::.:.::::..::.. ..: ...: : :
XP_011 VRQGLKCEGCGLNYHKRCAFKIPNNCSGVRRRRLSNVSLTGVSTIRTSSAELSTSAPDEP
100 110 120 130 140 150
230 240 250 260 270
pF1KE3 LSRSTTELLPRRPPSSS-----SSSSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPT
: .. . .. :: : . :...:: ::::.:::.:.:::::::::.::::::::
XP_011 LLSPVSPGFEQKSPSESFIGREKRSNSQSYIGRPIHLDKILMSKVKVPHTFVIHSYTRPT
160 170 180 190 200 210
280 290 300 310 320
pF1KE3 VCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEALINGD---------VPME
::: ::::::::::::::::::.:::::::: .:::.::::. :::: : ::
XP_011 VCQYCKKLLKGLFRQGLQCKDCRFNCHKRCAPKVPNNCLGEVTINGDLLSPGAESDVVME
220 230 240 250 260 270
330 340 350 360 370
pF1KE3 EATDFSEADK-SALMDESEDSGVIPGSHSENALHASEEEEGEGGK------------AQS
:..: ..... :.:::. :.. : . .: :. ... :: . :
XP_011 EGSDDNDSERNSGLMDDMEEAMV---QDAEMAMAECQNDSGEMQDPDPDHEDANRTISPS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE3 SLGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTT
. . ::::::::::.:: :::::...:::.:::..::::::::::::: ::::::::.:
XP_011 TSNNIPLMRVVQSVKHTKRKSSTVMKEGWMVHYTSKDTLRKRHYWRLDSKCITLFQNDTG
340 350 360 370 380 390
440 450 460 470 480
pF1KE3 NRYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGEM---PGG-TPGGP-
.::::::::::::..: ... .:.: :.:::::::.:::..:.::: :.. .:..
XP_011 SRYYKEIPLSEILSLEPVKTSALIPNGANPHCFEITTANVVYYVGENVVNPSSPSPNNSV
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE3 --SGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIAT
:: ::..:: :: ::..:::::: . . . : ::. :.:::::: ::::::::.:
XP_011 LTSGVGADVARMWEIAIQHALMPVIPKGSSVGTGTNLHRDISVSISVSNCQIQENVDIST
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE3 VYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRH
::::::::::::::::.::::::::::::::.:.::::::::::::::::::::::.:.:
XP_011 VYQIFPDEVLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHH
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE3 PGIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHF
::.:::::::::::.::::::::::::::::::::::::::..:::::::::::::::::
XP_011 PGVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHF
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE3 KNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.:
XP_011 KNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKG
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE3 YNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNL
:::::::::::::.::::::::::::::::.::::::::::: .::..:: ::::::::
XP_011 YNRSLDMWSVGVIIYVSLSGTFPFNEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE3 LQVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPL-
:::::::::::::.:::::::.::::::::::: :.::::::::::: :::..:.:. :
XP_011 LQVKMRKRYSVDKTLSHPWLQDYQTWLDLRELECKIGERYITHESDDLRWEKYAGEQGLQ
760 770 780 790 800 810
850 860 870
pF1KE3 -PGSGLPTDRDLGGACPPQDHDMQGLAERISVL
: . . . . . .. .:..:.::.:.:
XP_011 YPTHLINPSASHSDTPETEETEMKALGERVSIL
820 830 840
>>NP_002733 (OMIM: 605435) serine/threonine-protein kina (912 aa)
initn: 4046 init1: 2056 opt: 2605 Z-score: 1166.7 bits: 227.1 E(85289): 3e-58
Smith-Waterman score: 4081; 68.4% identity (83.8% similar) in 914 aa overlap (2-878:19-912)
10 20 30 40
pF1KE3 MATAPSYPAGLPGSPGPGSPPPPGGLELQSPPPLLPQIPAPGS
:.: . : .::: ::: : :.: . :: .
NP_002 MSAPPVLRPPSPLLPVAAAAAAAAAALVPGS-GPG------------PAPFLAPVAAPVG
10 20 30 40
50 60 70 80 90
pF1KE3 GVSFHIQIGLTREFVLLPAASE----LAHVKQLACSIVDQKFPECGFYGLYDKILLFKHD
:.:::.::::.:: ::: : ::::...::::::::::::::::.:::::::.::
NP_002 GISFHLQIGLSREPVLLLQDSSGDYSLAHVREMACSIVDQKFPECGFYGMYDKILLFRHD
50 60 70 80 90 100
100 110 120 130 140 150
pF1KE3 PTSANLLQLVRSSGDIQEGDLVEVVLSASATFEDFQIRPHALTVHSYRAPAFCDHCGEML
::: :.::::....:::::::.:::::::::::::::::::: :::::::::::::::::
NP_002 PTSENILQLVKAASDIQEGDLIEVVLSASATFEDFQIRPHALFVHSYRAPAFCDHCGEML
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE3 FGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSSTSLASGHSVRLGTSESLPCTA
.:::::::::.::::::::::::.:::::::.:.::::..::.. ..: ...: .
NP_002 WGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRRRRLSNVSLTGVSTIRTSSAELSTSAP
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE3 EE--LSRSTTELLPRRPPSSSSSSSASSYTGRPIELDKMLLSKVKVPHTFLIHSYTRPTV
.: :..: .: . : :.:.: : ::::.:::.:.:::::::::.:::::::::
NP_002 DEPLLQKSPSESFIGREKRSNSQS----YIGRPIHLDKILMSKVKVPHTFVIHSYTRPTV
230 240 250 260 270 280
280 290 300 310 320
pF1KE3 CQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEALINGD---------VPMEE
:: ::::::::::::::::::.:::::::: .:::.::::. :::: : :::
NP_002 CQYCKKLLKGLFRQGLQCKDCRFNCHKRCAPKVPNNCLGEVTINGDLLSPGAESDVVMEE
290 300 310 320 330 340
330 340 350 360 370
pF1KE3 ATDFSEADK-SALMDESEDSGVIPGSHSENALHASEEEEGEGGK------------AQSS
..: ..... :.:::. :.. : . .: :. ... :: . :.
NP_002 GSDDNDSERNSGLMDDMEEAMV---QDAEMAMAECQNDSGEMQDPDPDHEDANRTISPST
350 360 370 380 390 400
380 390 400 410 420 430
pF1KE3 LGYIPLMRVVQSVRHTTRKSSTTLREGWVVHYSNKDTLRKRHYWRLDCKCITLFQNNTTN
. ::::::::::.:: :::::...:::.:::..::::::::::::: ::::::::.: .
NP_002 SNNIPLMRVVQSVKHTKRKSSTVMKEGWMVHYTSKDTLRKRHYWRLDSKCITLFQNDTGS
410 420 430 440 450 460
440 450 460 470 480
pF1KE3 RYYKEIPLSEILTVESAQNFSLVPPGTNPHCFEIVTANATYFVGEM---PGG-TPGGP--
::::::::::::..: ... .:.: :.:::::::.:::..:.::: :.. .:..
NP_002 RYYKEIPLSEILSLEPVKTSALIPNGANPHCFEITTANVVYYVGENVVNPSSPSPNNSVL
470 480 490 500 510 520
490 500 510 520 530 540
pF1KE3 -SGQGAEAARGWETAIRQALMPVILQDAPSAPGHAPHRQASLSISVSNSQIQENVDIATV
:: ::..:: :: ::..:::::: . . . : ::. :.:::::: ::::::::.::
NP_002 TSGVGADVARMWEIAIQHALMPVIPKGSSVGTGTNLHRDISVSISVSNCQIQENVDISTV
530 540 550 560 570 580
550 560 570 580 590 600
pF1KE3 YQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQSLRHP
:::::::::::::::.::::::::::::::.:.::::::::::::::::::::::.:.::
NP_002 YQIFPDEVLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHP
590 600 610 620 630 640
610 620 630 640 650 660
pF1KE3 GIVNLECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFK
:.:::::::::::.::::::::::::::::::::::::::..::::::::::::::::::
NP_002 GVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFK
650 660 670 680 690 700
670 680 690 700 710 720
pF1KE3 NIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.::
NP_002 NIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGY
710 720 730 740 750 760
730 740 750 760 770 780
pF1KE3 NRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQNAAFMYPASPWSHISAGAIDLINNLL
::::::::::::.::::::::::::::::.::::::::::: .::..:: :::::::::
NP_002 NRSLDMWSVGVIIYVSLSGTFPFNEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLL
770 780 790 800 810 820
790 800 810 820 830 840
pF1KE3 QVKMRKRYSVDKSLSHPWLQEYQTWLDLRELEGKMGERYITHESDDARWEQFAAEHPL--
::::::::::::.:::::::.::::::::::: :.::::::::::: :::..:.:. :
NP_002 QVKMRKRYSVDKTLSHPWLQDYQTWLDLRELECKIGERYITHESDDLRWEKYAGEQGLQY
830 840 850 860 870 880
850 860 870
pF1KE3 PGSGLPTDRDLGGACPPQDHDMQGLAERISVL
: . . . . . .. .:..:.::.:.:
NP_002 PTHLINPSASHSDTPETEETEMKALGERVSIL
890 900 910
878 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:19:39 2016 done: Sun Nov 6 13:19:41 2016
Total Scan time: 15.020 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]