FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3328, 936 aa 1>>>pF1KE3328 936 - 936 aa - 936 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.3323+/-0.00194; mu= -3.8411+/- 0.111 mean_var=483.9509+/-109.864, 0's: 0 Z-trim(105.9): 713 B-trim: 235 in 1/49 Lambda= 0.058301 statistics sampled from 7850 (8688) to 7850 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.267), width: 16 Scan time: 3.900 The best scores are: opt bits E(32554) CCDS44161.2 TNNI3K gene_id:100526835|Hs108|chr1 ( 949) 6255 543.0 1e-153 CCDS664.1 TNNI3K gene_id:51086|Hs108|chr1 ( 835) 5507 480.0 8.2e-135 CCDS663.2 FPGT gene_id:8790|Hs108|chr1 ( 607) 754 80.0 1.5e-14 >>CCDS44161.2 TNNI3K gene_id:100526835|Hs108|chr1 (949 aa) initn: 6255 init1: 6255 opt: 6255 Z-score: 2873.2 bits: 543.0 E(32554): 1e-153 Smith-Waterman score: 6255; 100.0% identity (100.0% similar) in 936 aa overlap (1-936:14-949) 10 20 30 40 pF1KE3 MAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE ::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MRAVRRGLREGGAMAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE3 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE3 TILLIHSDEWKKKVSESYVITIERLEDDLQIKEKELTELRNIFGSDEAFSKVNLNYRTEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TILLIHSDEWKKKVSESYVITIERLEDDLQIKEKELTELRNIFGSDEAFSKVNLNYRTEN 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE3 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGAD 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE3 IQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 IQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE3 LKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFG 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE3 HHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSE 370 380 390 400 410 420 410 420 430 440 450 460 pF1KE3 TAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADM 430 440 450 460 470 480 470 480 490 500 510 520 pF1KE3 NLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLKHYKRPQDELPCNEYSQPGGDGSYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLKHYKRPQDELPCNEYSQPGGDGSYV 490 500 510 520 530 540 530 540 550 560 570 580 pF1KE3 SVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKI 550 560 570 580 590 600 590 600 610 620 630 640 pF1KE3 VAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGS 610 620 630 640 650 660 650 660 670 680 690 700 pF1KE3 LFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVAD 670 680 690 700 710 720 710 720 730 740 750 760 pF1KE3 FGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFA 730 740 750 760 770 780 770 780 790 800 810 820 pF1KE3 HLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNI 790 800 810 820 830 840 830 840 850 860 870 880 pF1KE3 ELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNARSYAALSQSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNARSYAALSQSAG 850 860 870 880 890 900 890 900 910 920 930 pF1KE3 QYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHFHSCRNSSSFEDSS ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHFHSCRNSSSFEDSS 910 920 930 940 >>CCDS664.1 TNNI3K gene_id:51086|Hs108|chr1 (835 aa) initn: 5507 init1: 5507 opt: 5507 Z-score: 2533.8 bits: 480.0 E(32554): 8.2e-135 Smith-Waterman score: 5507; 99.9% identity (100.0% similar) in 823 aa overlap (114-936:13-835) 90 100 110 120 130 140 pF1KE3 GNGGSTLCALQCLEKLYGDKWNSFTILLIHSDEWKKKVSESYVITIERLEDDLQIKEKEL .::::::::::::::::::::::::::::: CCDS66 MGNYKSRPTQTCTDEWKKKVSESYVITIERLEDDLQIKEKEL 10 20 30 40 150 160 170 180 190 200 pF1KE3 TELRNIFGSDEAFSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TELRNIFGSDEAFSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGF 50 60 70 80 90 100 210 220 230 240 250 260 pF1KE3 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 110 120 130 140 150 160 270 280 290 300 310 320 pF1KE3 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 170 180 190 200 210 220 330 340 350 360 370 380 pF1KE3 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGK 230 240 250 260 270 280 390 400 410 420 430 440 pF1KE3 FEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 FEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHT 290 300 310 320 330 340 450 460 470 480 490 500 pF1KE3 GLHSACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GLHSACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLK 350 360 370 380 390 400 510 520 530 540 550 560 pF1KE3 HYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 HYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSE 410 420 430 440 450 460 570 580 590 600 610 620 pF1KE3 IEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 IEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVI 470 480 490 500 510 520 630 640 650 660 670 680 pF1KE3 QFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 QFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQ 530 540 550 560 570 580 690 700 710 720 730 740 pF1KE3 PIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 PIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRY 590 600 610 620 630 640 750 760 770 780 790 800 pF1KE3 TIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGW 650 660 670 680 690 700 810 820 830 840 850 860 pF1KE3 NACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 NACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAA 710 720 730 740 750 760 870 880 890 900 910 920 pF1KE3 LRSRFELEYALNARSYAALSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 LRSRFELEYALNARSYAALSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHF 770 780 790 800 810 820 930 pF1KE3 HSCRNSSSFEDSS ::::::::::::: CCDS66 HSCRNSSSFEDSS 830 >>CCDS663.2 FPGT gene_id:8790|Hs108|chr1 (607 aa) initn: 754 init1: 754 opt: 754 Z-score: 374.7 bits: 80.0 E(32554): 1.5e-14 Smith-Waterman score: 754; 94.2% identity (98.3% similar) in 121 aa overlap (1-121:14-134) 10 20 30 40 pF1KE3 MAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE ::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MRAVRRGLREGGAMAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE3 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE3 TILLIHSDEWKKKVSESYVITIERLEDDLQIKEKELTELRNIFGSDEAFSKVNLNYRTEN ::::::: ..... CCDS66 TILLIHSGGYSQRLPNASALGKIFTALPLGNPIYQMLELKLAMYIDFPLNMNPGILVTCA 130 140 150 160 170 180 936 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 19:16:16 2016 done: Sun Nov 6 19:16:17 2016 Total Scan time: 3.900 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]