Result of FASTA (omim) for pF1KE3330
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3330, 943 aa
  1>>>pF1KE3330 943 - 943 aa - 943 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.8138+/-0.000604; mu= -18.6079+/- 0.037
 mean_var=814.5618+/-180.167, 0's: 0 Z-trim(119.0): 709  B-trim: 0 in 0/57
 Lambda= 0.044938
 statistics sampled from 31894 (32625) to 31894 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.383), width:  16
 Scan time: 12.650

The best scores are:                                      opt bits E(85289)
NP_004551 (OMIM: 113000,268310,602337) tyrosine-pr ( 943) 6520 439.8 3.2e-122
XP_016870251 (OMIM: 113000,268310,602337) PREDICTE ( 940) 6318 426.7 2.8e-118
XP_005252065 (OMIM: 113000,268310,602337) PREDICTE ( 803) 5567 377.9 1.1e-103
XP_016870252 (OMIM: 113000,268310,602337) PREDICTE ( 803) 5567 377.9 1.1e-103
XP_006717184 (OMIM: 113000,268310,602337) PREDICTE ( 803) 5567 377.9 1.1e-103
XP_005252066 (OMIM: 113000,268310,602337) PREDICTE ( 542) 3682 255.5 5.5e-67
NP_005003 (OMIM: 602336) inactive tyrosine-protein ( 937) 3657 254.1 2.4e-66
XP_016856865 (OMIM: 602336) PREDICTED: inactive ty ( 917) 3642 253.2 4.6e-66
XP_011539828 (OMIM: 602336) PREDICTED: inactive ty ( 874) 3606 250.8 2.2e-65
XP_016856866 (OMIM: 602336) PREDICTED: inactive ty ( 874) 3606 250.8 2.2e-65
NP_001305133 (OMIM: 113000,268310,602337) tyrosine ( 432) 2713 192.5 3.9e-48
NP_001077061 (OMIM: 602336) inactive tyrosine-prot ( 393) 1768 131.2   1e-29
XP_011517010 (OMIM: 208150,601296,616325) PREDICTE ( 457)  876 73.5 2.8e-12
NP_001159753 (OMIM: 208150,601296,616325) muscle,  ( 773)  876 73.7 3.9e-12
NP_001159752 (OMIM: 208150,601296,616325) muscle,  ( 783)  876 73.7   4e-12
XP_016870223 (OMIM: 208150,601296,616325) PREDICTE ( 791)  876 73.8   4e-12
XP_005252053 (OMIM: 208150,601296,616325) PREDICTE ( 861)  876 73.8 4.2e-12
NP_005583 (OMIM: 208150,601296,616325) muscle, ske ( 869)  876 73.8 4.2e-12
XP_005252052 (OMIM: 208150,601296,616325) PREDICTE ( 871)  876 73.8 4.3e-12
XP_005252051 (OMIM: 208150,601296,616325) PREDICTE ( 879)  876 73.8 4.3e-12
XP_016877741 (OMIM: 191316) PREDICTED: NT-3 growth ( 448)  827 70.3 2.5e-11
XP_016877740 (OMIM: 191316) PREDICTED: NT-3 growth ( 456)  827 70.3 2.6e-11
XP_016877733 (OMIM: 191316) PREDICTED: NT-3 growth ( 727)  827 70.5 3.4e-11
XP_016877734 (OMIM: 191316) PREDICTED: NT-3 growth ( 727)  827 70.5 3.4e-11
XP_016877735 (OMIM: 191316) PREDICTED: NT-3 growth ( 727)  827 70.5 3.4e-11
XP_016877732 (OMIM: 191316) PREDICTED: NT-3 growth ( 727)  827 70.5 3.4e-11
XP_016877730 (OMIM: 191316) PREDICTED: NT-3 growth ( 763)  827 70.6 3.5e-11
NP_001230030 (OMIM: 191316) NT-3 growth factor rec ( 817)  827 70.6 3.7e-11
XP_006720607 (OMIM: 191316) PREDICTED: NT-3 growth ( 817)  827 70.6 3.7e-11
NP_002521 (OMIM: 191316) NT-3 growth factor recept ( 825)  827 70.6 3.7e-11
XP_006720606 (OMIM: 191316) PREDICTED: NT-3 growth ( 825)  827 70.6 3.7e-11
XP_016877729 (OMIM: 191316) PREDICTED: NT-3 growth ( 825)  827 70.6 3.7e-11
XP_011517020 (OMIM: 600456,613886) PREDICTED: BDNF ( 822)  820 70.1 5.1e-11
XP_016870243 (OMIM: 600456,613886) PREDICTED: BDNF ( 822)  820 70.1 5.1e-11
XP_016870241 (OMIM: 600456,613886) PREDICTED: BDNF ( 822)  820 70.1 5.1e-11
XP_016870242 (OMIM: 600456,613886) PREDICTED: BDNF ( 822)  820 70.1 5.1e-11
NP_001018074 (OMIM: 600456,613886) BDNF/NT-3 growt ( 822)  820 70.1 5.1e-11
NP_006171 (OMIM: 600456,613886) BDNF/NT-3 growth f ( 838)  820 70.2 5.1e-11
XP_005252058 (OMIM: 600456,613886) PREDICTED: BDNF ( 838)  820 70.2 5.1e-11
XP_016870240 (OMIM: 600456,613886) PREDICTED: BDNF ( 838)  820 70.2 5.1e-11
XP_005252060 (OMIM: 600456,613886) PREDICTED: BDNF ( 838)  820 70.2 5.1e-11
XP_005252061 (OMIM: 600456,613886) PREDICTED: BDNF ( 838)  820 70.2 5.1e-11
NP_001007793 (OMIM: 155240,191315,256800) high aff ( 760)  795 68.5 1.5e-10
NP_001012331 (OMIM: 155240,191315,256800) high aff ( 790)  795 68.5 1.5e-10
NP_002520 (OMIM: 155240,191315,256800) high affini ( 796)  795 68.5 1.5e-10
NP_001278909 (OMIM: 134935) fibroblast growth fact ( 734)  698 62.2 1.1e-08
XP_011507889 (OMIM: 191311,271665) PREDICTED: disc ( 855)  695 62.1 1.4e-08
NP_006173 (OMIM: 191311,271665) discoidin domain-c ( 855)  695 62.1 1.4e-08
XP_011507888 (OMIM: 191311,271665) PREDICTED: disc ( 855)  695 62.1 1.4e-08
NP_001014796 (OMIM: 191311,271665) discoidin domai ( 855)  695 62.1 1.4e-08


>>NP_004551 (OMIM: 113000,268310,602337) tyrosine-protei  (943 aa)
 initn: 6520 init1: 6520 opt: 6520  Z-score: 2315.3  bits: 439.8 E(85289): 3.2e-122
Smith-Waterman score: 6520; 99.8% identity (100.0% similar) in 943 aa overlap (1-943:1-943)

               10        20        30        40        50        60
pF1KE3 MARGSALPRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MARGSALPRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 FLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 RIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 ACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 ARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANC
       ::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 MRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 GHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIAC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 LFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE3 EDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE3 GVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE3 AGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE3 PEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAW
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE3 VYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSN
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE3 VSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYIPVNGYQPVPAYGAYLPNFYPV
       ::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_004 VSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFYPV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE3 QIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNA
              850       860       870       880       890       900

              910       920       930       940   
pF1KE3 PEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
       :::::::::::::::::::::::::::::::::::::::::::
NP_004 PEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
              910       920       930       940   

>>XP_016870251 (OMIM: 113000,268310,602337) PREDICTED: t  (940 aa)
 initn: 6314 init1: 6314 opt: 6318  Z-score: 2244.6  bits: 426.7 E(85289): 2.8e-118
Smith-Waterman score: 6318; 98.0% identity (98.7% similar) in 933 aa overlap (12-943:8-940)

               10        20        30         40        50         
pF1KE3 MARGSALPRRPLLCIPAVWAAAALLLSVSR-TSGEVEVLDPNDPLGPLDGQDGPIPTLKG
                  :.:. ..  .     :::    :::::::::::::::::::::::::::
XP_016     MCLLGTFLVCVETLGFGCISSSSVSYYIFGEVEVLDPNDPLGPLDGQDGPIPTLKG
                   10        20        30        40        50      

      60        70        80        90       100       110         
pF1KE3 YFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSR
         60        70        80        90       100       110      

     120       130       140       150       160       170         
pF1KE3 LRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRG
        120       130       140       150       160       170      

     180       190       200       210       220       230         
pF1KE3 IACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLC
        180       190       200       210       220       230      

     240       250       260       270       280       290         
pF1KE3 DARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAAN
       :::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAAN
        240       250       260       270       280       290      

     300       310       320       330       340       350         
pF1KE3 CMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELG
        300       310       320       330       340       350      

     360       370       380       390       400       410         
pF1KE3 GGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIA
        360       370       380       390       400       410      

     420       430       440       450       460       470         
pF1KE3 CLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEEL
        420       430       440       450       460       470      

     480       490       500       510       520       530         
pF1KE3 GEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCL
        480       490       500       510       520       530      

     540       550       560       570       580       590         
pF1KE3 LGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQI
        540       550       560       570       580       590      

     600       610       620       630       640       650         
pF1KE3 AAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWM
        600       610       620       630       640       650      

     660       670       680       690       700       710         
pF1KE3 APEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPA
        660       670       680       690       700       710      

     720       730       740       750       760       770         
pF1KE3 WVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVS
        720       730       740       750       760       770      

     780       790       800       810       820       830         
pF1KE3 NVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYIPVNGYQPVPAYGAYLPNFYP
       :::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_016 NVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFYP
        780       790       800       810       820       830      

     840       850       860       870       880       890         
pF1KE3 VQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQN
        840       850       860       870       880       890      

     900       910       920       930       940   
pF1KE3 APEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
       ::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
        900       910       920       930       940

>>XP_005252065 (OMIM: 113000,268310,602337) PREDICTED: t  (803 aa)
 initn: 5567 init1: 5567 opt: 5567  Z-score: 1982.2  bits: 377.9 E(85289): 1.1e-103
Smith-Waterman score: 5567; 99.8% identity (100.0% similar) in 803 aa overlap (141-943:1-803)

              120       130       140       150       160       170
pF1KE3 IRKTEYGSRLRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHE
                                     ::::::::::::::::::::::::::::::
XP_005                               MKTITATGVLFVRLGPTHSPNHNFQDDYHE
                                             10        20        30

              180       190       200       210       220       230
pF1KE3 DGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPS
               40        50        60        70        80        90

              240       250       260       270       280       290
pF1KE3 FCHFVFPLCDARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALP
       ::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
XP_005 FCHFVFPLCDARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALP
              100       110       120       130       140       150

              300       310       320       330       340       350
pF1KE3 MPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHL
              160       170       180       190       200       210

              360       370       380       390       400       410
pF1KE3 SSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVP
              220       230       240       250       260       270

              420       430       440       450       460       470
pF1KE3 SIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISL
              280       290       300       310       320       330

              480       490       500       510       520       530
pF1KE3 SAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRAR
              340       350       360       370       380       390

              540       550       560       570       580       590
pF1KE3 LQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP
              400       410       420       430       440       450

              600       610       620       630       640       650
pF1KE3 DFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLG
              460       470       480       490       500       510

              660       670       680       690       700       710
pF1KE3 NSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQV
              520       530       540       550       560       570

              720       730       740       750       760       770
pF1KE3 LPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQT
              580       590       600       610       620       630

              780       790       800       810       820       830
pF1KE3 SSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYIPVNGYQPVPAY
       ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_005 SSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAY
              640       650       660       670       680       690

              840       850       860       870       880       890
pF1KE3 GAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALL
              700       710       720       730       740       750

              900       910       920       930       940   
pF1KE3 SEGADDTQNAPEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEGADDTQNAPEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
              760       770       780       790       800   

>>XP_016870252 (OMIM: 113000,268310,602337) PREDICTED: t  (803 aa)
 initn: 5567 init1: 5567 opt: 5567  Z-score: 1982.2  bits: 377.9 E(85289): 1.1e-103
Smith-Waterman score: 5567; 99.8% identity (100.0% similar) in 803 aa overlap (141-943:1-803)

              120       130       140       150       160       170
pF1KE3 IRKTEYGSRLRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHE
                                     ::::::::::::::::::::::::::::::
XP_016                               MKTITATGVLFVRLGPTHSPNHNFQDDYHE
                                             10        20        30

              180       190       200       210       220       230
pF1KE3 DGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPS
               40        50        60        70        80        90

              240       250       260       270       280       290
pF1KE3 FCHFVFPLCDARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALP
       ::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCHFVFPLCDARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALP
              100       110       120       130       140       150

              300       310       320       330       340       350
pF1KE3 MPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHL
              160       170       180       190       200       210

              360       370       380       390       400       410
pF1KE3 SSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVP
              220       230       240       250       260       270

              420       430       440       450       460       470
pF1KE3 SIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISL
              280       290       300       310       320       330

              480       490       500       510       520       530
pF1KE3 SAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRAR
              340       350       360       370       380       390

              540       550       560       570       580       590
pF1KE3 LQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP
              400       410       420       430       440       450

              600       610       620       630       640       650
pF1KE3 DFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLG
              460       470       480       490       500       510

              660       670       680       690       700       710
pF1KE3 NSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQV
              520       530       540       550       560       570

              720       730       740       750       760       770
pF1KE3 LPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQT
              580       590       600       610       620       630

              780       790       800       810       820       830
pF1KE3 SSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYIPVNGYQPVPAY
       ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_016 SSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAY
              640       650       660       670       680       690

              840       850       860       870       880       890
pF1KE3 GAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALL
              700       710       720       730       740       750

              900       910       920       930       940   
pF1KE3 SEGADDTQNAPEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGADDTQNAPEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
              760       770       780       790       800   

>>XP_006717184 (OMIM: 113000,268310,602337) PREDICTED: t  (803 aa)
 initn: 5567 init1: 5567 opt: 5567  Z-score: 1982.2  bits: 377.9 E(85289): 1.1e-103
Smith-Waterman score: 5567; 99.8% identity (100.0% similar) in 803 aa overlap (141-943:1-803)

              120       130       140       150       160       170
pF1KE3 IRKTEYGSRLRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHE
                                     ::::::::::::::::::::::::::::::
XP_006                               MKTITATGVLFVRLGPTHSPNHNFQDDYHE
                                             10        20        30

              180       190       200       210       220       230
pF1KE3 DGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPS
               40        50        60        70        80        90

              240       250       260       270       280       290
pF1KE3 FCHFVFPLCDARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALP
       ::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
XP_006 FCHFVFPLCDARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALP
              100       110       120       130       140       150

              300       310       320       330       340       350
pF1KE3 MPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHL
              160       170       180       190       200       210

              360       370       380       390       400       410
pF1KE3 SSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVP
              220       230       240       250       260       270

              420       430       440       450       460       470
pF1KE3 SIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISL
              280       290       300       310       320       330

              480       490       500       510       520       530
pF1KE3 SAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRAR
              340       350       360       370       380       390

              540       550       560       570       580       590
pF1KE3 LQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP
              400       410       420       430       440       450

              600       610       620       630       640       650
pF1KE3 DFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLG
              460       470       480       490       500       510

              660       670       680       690       700       710
pF1KE3 NSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQV
              520       530       540       550       560       570

              720       730       740       750       760       770
pF1KE3 LPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQT
              580       590       600       610       620       630

              780       790       800       810       820       830
pF1KE3 SSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYIPVNGYQPVPAY
       ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_006 SSLSTSPVSNVSNARYVGPKQKAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAY
              640       650       660       670       680       690

              840       850       860       870       880       890
pF1KE3 GAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALL
              700       710       720       730       740       750

              900       910       920       930       940   
pF1KE3 SEGADDTQNAPEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEGADDTQNAPEDGAQSTVQEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
              760       770       780       790       800   

>>XP_005252066 (OMIM: 113000,268310,602337) PREDICTED: t  (542 aa)
 initn: 3682 init1: 3682 opt: 3682  Z-score: 1323.6  bits: 255.5 E(85289): 5.5e-67
Smith-Waterman score: 3682; 99.8% identity (100.0% similar) in 542 aa overlap (402-943:1-542)

             380       390       400       410       420       430 
pF1KE3 MEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIACLFFLVCMCRNK
                                     ::::::::::::::::::::::::::::::
XP_005                               MGILYILVPSIAIPLVIACLFFLVCMCRNK
                                             10        20        30

             440       450       460       470       480       490 
pF1KE3 QKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGH
               40        50        60        70        80        90

             500       510       520       530       540       550 
pF1KE3 LFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSM
              100       110       120       130       140       150

             560       570       580       590       600       610 
pF1KE3 IFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHV
              160       170       180       190       200       210

             620       630       640       650       660       670 
pF1KE3 VHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSI
              220       230       240       250       260       270

             680       690       700       710       720       730 
pF1KE3 DSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNE
              280       290       300       310       320       330

             740       750       760       770       780       790 
pF1KE3 FPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYVGPKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYVGPKQ
              340       350       360       370       380       390

             800       810       820       830       840       850 
pF1KE3 KAPPFPQPQFIPMKGQIRPMVPPPQLYIPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQV
       :::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_005 KAPPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQV
              400       410       420       430       440       450

             860       870       880       890       900       910 
pF1KE3 PPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNAPEDGAQSTVQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNAPEDGAQSTVQE
              460       470       480       490       500       510

             920       930       940   
pF1KE3 AEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
       ::::::::::::::::::::::::::::::::
XP_005 AEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
              520       530       540  

>>NP_005003 (OMIM: 602336) inactive tyrosine-protein kin  (937 aa)
 initn: 2749 init1: 1334 opt: 3657  Z-score: 1312.2  bits: 254.1 E(85289): 2.4e-66
Smith-Waterman score: 3657; 57.6% identity (79.1% similar) in 946 aa overlap (8-942:4-936)

               10        20        30        40        50        60
pF1KE3 MARGSALPRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGY
              :::     : .   :::::..  ....   :. .  : : .. .      :  
NP_005     MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDS
                   10        20        30        40        50      

               70        80        90       100       110       120
pF1KE3 FLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRL
       .:.. ::.::::   :::: :::::.:::::..::.::::::::::::. .:.: :::::
NP_005 YLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRL
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KE3 RIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGI
       ::..::::::::.::::::: .....::::::..::  . . ...:.:.:::::::::::
NP_005 RIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGI
        120       130       140       150       160       170      

              190       200       210       220       230       240
pF1KE3 ACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCD
       ::::::::::.:..::.:::::::.:::::::::::.::::.::::::::.::..:: ::
NP_005 ACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCD
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KE3 ARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANC
         : .::::.:::::::.::. ::. :: .:::::.:::::.::.:: ::.::::.::::
NP_005 ETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANC
        240       250       260       270       280       290      

               310       320       330       340       350         
pF1KE3 MRIGIP-AERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELG
       .::::: :. ... :.:::..:.:::::.:.::::.:::::  :.::.: ...  ::::.
NP_005 IRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELN
        300       310       320       330       340       350      

     360       370       380       390          400       410      
pF1KE3 GGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDS---SKMGILYILVPSIAIPL
       :::.::::::.: :.::::: ..: . .:::.:.:. .::   .:: ::::::::.::::
NP_005 GGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEILYILVPSVAIPL
        360       370       380       390       400       410      

        420       430       440       450       460        470     
pF1KE3 VIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHK-QAKLKEISLSAVRF
       .:: :::..:.:::.:: :.:.: .::     .:..:: ..: .: ..: ::. ::::::
NP_005 AIALLFFFICVCRNNQK-SSSAPVQRQPKHVRGQNVEMSMLNAYKPKSKAKELPLSAVRF
        420       430        440       450       460       470     

         480       490       500       510       520       530     
pF1KE3 MEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPN
       ::::::  :::.:::::. :.  ...: ::::::::  .     ::..:: : :.:.:::
NP_005 MEELGECAFGKIYKGHLYLPGM-DHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPN
         480       490        500       510       520       530    

         540       550       560       570        580       590    
pF1KE3 VVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVG-STDDDRTVKSALEPPDFVH
       .:::::.::..::. :.: : ..:::::::.::::::::: :.:.: ::::.:.  ::.:
NP_005 IVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLH
          540       550       560       570       580       590    

          600       610       620       630       640       650    
pF1KE3 LVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLL
       .. ::::::::::::  ::::::.::.:. ..:.:::::::: ::.:.::::.. ..:::
NP_005 IAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSLL
          600       610       620       630       640       650    

          660       670       680       690       700       710    
pF1KE3 PIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCP
       ::::: :::::::::: ::::::.::::::.::.::::: :.:::.:.::.:.::.::: 
NP_005 PIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCS
          660       670       680       690       700       710    

          720       730       740       750       760       770    
pF1KE3 DDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLS
       .:::  .:.:: :::::.::::::::::: :::.: .::...::.  ::.. ::::.:::
NP_005 EDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLS
          720       730       740       750       760       770    

          780       790          800       810       820       830 
pF1KE3 TSPVSNVSNARYVGPKQKAPP---FPQPQFIPMKGQIRPMVPPPQLYIPVNGYQPVPAYG
       .:::::.:: ::  :.   :     :: :   . : : : .:  : .::.:::   :.:.
NP_005 ASPVSNLSNPRY--PNYMFPSQGITPQGQ---IAGFIGPPIPQNQRFIPINGYPIPPGYA
          780         790       800          810       820         

             840       850       860       870       880       890 
pF1KE3 AYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLS
       :.    :    : ..  :. ::   ::  :  :.:::::::.::. ::. :  .    : 
NP_005 AFPAAHYQPTGPPRVI-QHCPP---PKSRSPSSASGSTSTGHVTSLPSSGSNQEANIPLL
     830       840        850          860       870       880     

             900         910       920       930       940   
pF1KE3 EGADDTQNAPEDGAQSTV--QEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
          .   : :  :   ::  .....  . .  .. :::: .     :.... : 
NP_005 PHMS-IPNHP-GGMGITVFGNKSQKPYKIDSKQASLLGDANIHGHTESMISAEL
          890        900       910       920       930       

>>XP_016856865 (OMIM: 602336) PREDICTED: inactive tyrosi  (917 aa)
 initn: 2725 init1: 1315 opt: 3642  Z-score: 1307.1  bits: 253.2 E(85289): 4.6e-66
Smith-Waterman score: 3642; 59.4% identity (80.7% similar) in 902 aa overlap (53-942:28-916)

             30        40        50         60        70        80 
pF1KE3 ALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTL-KGYFLNFLEPVNNITIVQGQTAIL
                                     : :.: :  .:.. ::.::::   :::: :
XP_016    MMLLPTESLLSLTKVSIHFIIPFLACFPDPSLIKDSYLTLDEPMNNITTSLGQTAEL
                  10        20        30        40        50       

              90       100       110       120       130       140 
pF1KE3 HCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGM
       ::::.:::::..::.::::::::::::. .:.: :::::::..::::::::.::::::: 
XP_016 HCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGK
        60        70        80        90       100       110       

             150       160       170       180       190       200 
pF1KE3 KTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGIACARFIGNRTIYVDSLQMQGE
       .....::::::..::  . . ...:.:.:::::::::::::::::::::.:..::.::::
XP_016 EVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGE
       120       130       140       150       160       170       

             210       220       230       240       250       260 
pF1KE3 IENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCDARSRAPKPRELCRDECEVLES
       :::.:::::::::::.::::.::::::::.::..:: ::  : .::::.:::::::.::.
XP_016 IENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILEN
       180       190       200       210       220       230       

             270       280       290       300        310       320
pF1KE3 DLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIP-AERLGRYHQCYNGS
        ::. :: .:::::.:::::.::.:: ::.::::.::::.::::: :. ... :.:::..
XP_016 VLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNST
       240       250       260       270       280       290       

              330       340       350       360       370       380
pF1KE3 GMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGPWCFTQ
       :.:::::.:.::::.:::::  :.::.: ...  ::::.:::.::::::.: :.::::: 
XP_016 GVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTL
       300       310       320       330       340       350       

              390          400       410       420       430       
pF1KE3 NKNVRMELCDVPSCSPRDS---SKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASAS
       ..: . .:::.:.:. .::   .:: ::::::::.::::.:: :::..:.:::.:: :.:
XP_016 DENFKSDLCDIPACDSKDSKEKNKMEILYILVPSVAIPLAIALLFFFICVCRNNQK-SSS
       360       370       380       390       400       410       

       440       450       460        470       480       490      
pF1KE3 TPQRRQLMASPSQDMEMPLINQHK-QAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPA
       .: .::     .:..:: ..: .: ..: ::. ::::::::::::  :::.:::::. :.
XP_016 APVQRQPKHVRGQNVEMSMLNAYKPKSKAKELPLSAVRFMEELGECAFGKIYKGHLYLPG
        420       430       440       450       460       470      

        500       510       520       530       540       550      
pF1KE3 PGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYC
         ...: ::::::::  .     ::..:: : :.:.:::.:::::.::..::. :.: : 
XP_016 M-DHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYI
         480       490       500       510       520       530     

        560       570        580       590       600       610     
pF1KE3 SHGDLHEFLVMRSPHSDVG-STDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKD
       ..:::::::.::::::::: :.:.: ::::.:.  ::.:.. ::::::::::::  ::::
XP_016 NQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKD
         540       550       560       570       580       590     

         620       630       640       650       660       670     
pF1KE3 LATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDI
       ::.::.:. ..:.:::::::: ::.:.::::.. ..:::::::: :::::::::: ::::
XP_016 LAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDI
         600       610       620       630       640       650     

         680       690       700       710       720       730     
pF1KE3 WSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSR
       ::.::::::.::.::::: :.:::.:.::.:.::.::: .:::  .:.:: :::::.:::
XP_016 WSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSR
         660       670       680       690       700       710     

         740       750       760       770       780       790     
pF1KE3 RPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYVGPKQKAPP
       :::::::: :::.: .::...::.  ::.. ::::.:::.:::::.:: ::  :.   : 
XP_016 RPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNLSNPRY--PNYMFPS
         720       730       740       750       760         770   

            800       810       820       830       840       850  
pF1KE3 ---FPQPQFIPMKGQIRPMVPPPQLYIPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVP
           :: :   . : : : .:  : .::.:::   :.:.:.    :    : ..  :. :
XP_016 QGITPQGQ---IAGFIGPPIPQNQRFIPINGYPIPPGYAAFPAAHYQPTGPPRVI-QHCP
           780          790       800       810       820          

            860       870       880       890       900         910
pF1KE3 PQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNAPEDGAQSTV--Q
       :   ::  :  :.:::::::.::. ::. :  .    :    .   : :  :   ::  .
XP_016 P---PKSRSPSSASGSTSTGHVTSLPSSGSNQEANIPLLPHMS-IPNHP-GGMGITVFGN
     830          840       850       860        870        880    

              920       930       940   
pF1KE3 EAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA
       ....  . .  .. :::: .     :.... : 
XP_016 KSQKPYKIDSKQASLLGDANIHGHTESMISAEL
          890       900       910       

>>XP_011539828 (OMIM: 602336) PREDICTED: inactive tyrosi  (874 aa)
 initn: 2698 init1: 1315 opt: 3606  Z-score: 1294.7  bits: 250.8 E(85289): 2.2e-65
Smith-Waterman score: 3606; 59.7% identity (80.9% similar) in 886 aa overlap (68-942:1-873)

        40        50        60        70        80        90       
pF1KE3 LDPNDPLGPLDGQDGPIPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLK
                                     .::::   :::: :::::.:::::..::.:
XP_011                               MNNITTSLGQTAELHCKVSGNPPPTIRWFK
                                             10        20        30

       100       110       120       130       140       150       
pF1KE3 NDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPT
       :::::::::::. .:.: :::::::..::::::::.::::::: .....::::::..:: 
XP_011 NDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPP
               40        50        60        70        80        90

       160       170       180       190       200       210       
pF1KE3 HSPNHNFQDDYHEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTST
        . . ...:.:.:::::::::::::::::::::.:..::.:::::::.:::::::::::.
XP_011 PTASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSS
              100       110       120       130       140       150

       220       230       240       250       260       270       
pF1KE3 HLSDQCSQFAIPSFCHFVFPLCDARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPLI
       ::::.::::::::.::..:: ::  : .::::.:::::::.::. ::. :: .:::::.:
XP_011 HLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMI
              160       170       180       190       200       210

       280       290       300        310       320       330      
pF1KE3 LMRLQLPKCEALPMPESPDAANCMRIGIP-AERLGRYHQCYNGSGMDYRGTASTTKSGHQ
       ::::.::.:: ::.::::.::::.::::: :. ... :.:::..:.:::::.:.::::.:
XP_011 LMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQ
              220       230       240       250       260       270

        340       350       360       370       380       390      
pF1KE3 CQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSP
       ::::  :.::.: ...  ::::.:::.::::::.: :.::::: ..: . .:::.:.:. 
XP_011 CQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDS
              280       290       300       310       320       330

           400       410       420       430       440       450   
pF1KE3 RDS---SKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDME
       .::   .:: ::::::::.::::.:: :::..:.:::.::.: :.: .::     .:..:
XP_011 KDSKEKNKMEILYILVPSVAIPLAIALLFFFICVCRNNQKSS-SAPVQRQPKHVRGQNVE
              340       350       360       370        380         

           460        470       480       490       500       510  
pF1KE3 MPLINQHK-QAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDK
       : ..: .: ..: ::. ::::::::::::  :::.:::::. :.  ...: :::::::: 
XP_011 MSMLNAYKPKSKAKELPLSAVRFMEELGECAFGKIYKGHLYLPGM-DHAQLVAIKTLKDY
     390       400       410       420       430        440        

            520       530       540       550       560       570  
pF1KE3 AEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHS
        .     ::..:: : :.:.:::.:::::.::..::. :.: : ..:::::::.::::::
XP_011 NNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHS
      450       460       470       480       490       500        

             580       590       600       610       620       630 
pF1KE3 DVG-STDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKI
       ::: :.:.: ::::.:.  ::.:.. ::::::::::::  ::::::.::.:. ..:.:::
XP_011 DVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKI
      510       520       530       540       550       560        

             640       650       660       670       680       690 
pF1KE3 SDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQ
       ::::: ::.:.::::.. ..:::::::: :::::::::: ::::::.::::::.::.:::
XP_011 SDLGLSREIYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQ
      570       580       590       600       610       620        

             700       710       720       730       740       750 
pF1KE3 PYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGN
       :: :.:::.:.::.:.::.::: .:::  .:.:: :::::.::::::::::: :::.: .
XP_011 PYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEG
      630       640       650       660       670       680        

             760       770       780       790          800        
pF1KE3 LSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYVGPKQKAPP---FPQPQFIPMKGQI
       ::...::.  ::.. ::::.:::.:::::.:: ::  :.   :     :: :   . : :
XP_011 LSSHTSSTTPSGGNATTQTTSLSASPVSNLSNPRY--PNYMFPSQGITPQGQ---IAGFI
      690       700       710       720         730          740   

      810       820       830       840       850       860        
pF1KE3 RPMVPPPQLYIPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGS
        : .:  : .::.:::   :.:.:.    :    : ..  :. ::   ::  :  :.:::
XP_011 GPPIPQNQRFIPINGYPIPPGYAAFPAAHYQPTGPPRVI-QHCPP---PKSRSPSSASGS
           750       760       770       780           790         

      870       880       890       900         910       920      
pF1KE3 TSTGYVTTAPSNTSMADRAALLSEGADDTQNAPEDGAQSTV--QEAEEEEEGSVPETELL
       ::::.::. ::. :  .    :    .   : :  :   ::  .....  . .  .. ::
XP_011 TSTGHVTSLPSSGSNQEANIPLLPHMS-IPNHP-GGMGITVFGNKSQKPYKIDSKQASLL
     800       810       820        830        840       850       

        930       940   
pF1KE3 GDCDTLQVDEAQVQLEA
       :: .     :.... : 
XP_011 GDANIHGHTESMISAEL
       860       870    

>>XP_016856866 (OMIM: 602336) PREDICTED: inactive tyrosi  (874 aa)
 initn: 2698 init1: 1315 opt: 3606  Z-score: 1294.7  bits: 250.8 E(85289): 2.2e-65
Smith-Waterman score: 3606; 59.7% identity (80.9% similar) in 886 aa overlap (68-942:1-873)

        40        50        60        70        80        90       
pF1KE3 LDPNDPLGPLDGQDGPIPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLK
                                     .::::   :::: :::::.:::::..::.:
XP_016                               MNNITTSLGQTAELHCKVSGNPPPTIRWFK
                                             10        20        30

       100       110       120       130       140       150       
pF1KE3 NDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPT
       :::::::::::. .:.: :::::::..::::::::.::::::: .....::::::..:: 
XP_016 NDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPP
               40        50        60        70        80        90

       160       170       180       190       200       210       
pF1KE3 HSPNHNFQDDYHEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTST
        . . ...:.:.:::::::::::::::::::::.:..::.:::::::.:::::::::::.
XP_016 PTASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSS
              100       110       120       130       140       150

       220       230       240       250       260       270       
pF1KE3 HLSDQCSQFAIPSFCHFVFPLCDARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPLI
       ::::.::::::::.::..:: ::  : .::::.:::::::.::. ::. :: .:::::.:
XP_016 HLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMI
              160       170       180       190       200       210

       280       290       300        310       320       330      
pF1KE3 LMRLQLPKCEALPMPESPDAANCMRIGIP-AERLGRYHQCYNGSGMDYRGTASTTKSGHQ
       ::::.::.:: ::.::::.::::.::::: :. ... :.:::..:.:::::.:.::::.:
XP_016 LMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQ
              220       230       240       250       260       270

        340       350       360       370       380       390      
pF1KE3 CQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSP
       ::::  :.::.: ...  ::::.:::.::::::.: :.::::: ..: . .:::.:.:. 
XP_016 CQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDS
              280       290       300       310       320       330

           400       410       420       430       440       450   
pF1KE3 RDS---SKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDME
       .::   .:: ::::::::.::::.:: :::..:.:::.::.: :.: .::     .:..:
XP_016 KDSKEKNKMEILYILVPSVAIPLAIALLFFFICVCRNNQKSS-SAPVQRQPKHVRGQNVE
              340       350       360       370        380         

           460        470       480       490       500       510  
pF1KE3 MPLINQHK-QAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDK
       : ..: .: ..: ::. ::::::::::::  :::.:::::. :.  ...: :::::::: 
XP_016 MSMLNAYKPKSKAKELPLSAVRFMEELGECAFGKIYKGHLYLPGM-DHAQLVAIKTLKDY
     390       400       410       420       430        440        

            520       530       540       550       560       570  
pF1KE3 AEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHS
        .     ::..:: : :.:.:::.:::::.::..::. :.: : ..:::::::.::::::
XP_016 NNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHS
      450       460       470       480       490       500        

             580       590       600       610       620       630 
pF1KE3 DVG-STDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKI
       ::: :.:.: ::::.:.  ::.:.. ::::::::::::  ::::::.::.:. ..:.:::
XP_016 DVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKI
      510       520       530       540       550       560        

             640       650       660       670       680       690 
pF1KE3 SDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQ
       ::::: ::.:.::::.. ..:::::::: :::::::::: ::::::.::::::.::.:::
XP_016 SDLGLSREIYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQ
      570       580       590       600       610       620        

             700       710       720       730       740       750 
pF1KE3 PYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGN
       :: :.:::.:.::.:.::.::: .:::  .:.:: :::::.::::::::::: :::.: .
XP_016 PYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEG
      630       640       650       660       670       680        

             760       770       780       790          800        
pF1KE3 LSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYVGPKQKAPP---FPQPQFIPMKGQI
       ::...::.  ::.. ::::.:::.:::::.:: ::  :.   :     :: :   . : :
XP_016 LSSHTSSTTPSGGNATTQTTSLSASPVSNLSNPRY--PNYMFPSQGITPQGQ---IAGFI
      690       700       710       720         730          740   

      810       820       830       840       850       860        
pF1KE3 RPMVPPPQLYIPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGS
        : .:  : .::.:::   :.:.:.    :    : ..  :. ::   ::  :  :.:::
XP_016 GPPIPQNQRFIPINGYPIPPGYAAFPAAHYQPTGPPRVI-QHCPP---PKSRSPSSASGS
           750       760       770       780           790         

      870       880       890       900         910       920      
pF1KE3 TSTGYVTTAPSNTSMADRAALLSEGADDTQNAPEDGAQSTV--QEAEEEEEGSVPETELL
       ::::.::. ::. :  .    :    .   : :  :   ::  .....  . .  .. ::
XP_016 TSTGHVTSLPSSGSNQEANIPLLPHMS-IPNHP-GGMGITVFGNKSQKPYKIDSKQASLL
     800       810       820        830        840       850       

        930       940   
pF1KE3 GDCDTLQVDEAQVQLEA
       :: .     :.... : 
XP_016 GDANIHGHTESMISAEL
       860       870    




943 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 19:44:24 2016 done: Sun Nov  6 19:44:26 2016
 Total Scan time: 12.650 Total Display time:  0.390

Function used was FASTA [36.3.4 Apr, 2011]
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