Result of FASTA (omim) for
pF1KE3378
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3378, 1130 aa
1>>>pF1KE3378 1130 - 1130 aa - 1130 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 18.7409+/-0.000534; mu= -39.8063+/- 0.034
mean_var=986.9140+/-214.649, 0's: 0 Z-trim(122.7): 475 B-trim: 2367 in 1/59
Lambda= 0.040826
statistics sampled from 40765 (41288) to 40765 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.484), width: 16
Scan time: 16.420
The best scores are: opt bits E(85289)
NP_004681 (OMIM: 603473) serine/threonine-protein (1130) 7771 474.5 1.6e-132
XP_016866967 (OMIM: 603473) PREDICTED: serine/thre (1025) 7012 429.7 4.3e-119
XP_016866968 (OMIM: 603473) PREDICTED: serine/thre ( 993) 6594 405.1 1.1e-111
XP_011534554 (OMIM: 603473) PREDICTED: serine/thre (1001) 6588 404.7 1.4e-111
XP_016866966 (OMIM: 603473) PREDICTED: serine/thre (1034) 6588 404.7 1.4e-111
XP_016866964 (OMIM: 603473) PREDICTED: serine/thre (1163) 6588 404.8 1.6e-111
XP_016866963 (OMIM: 603473) PREDICTED: serine/thre (1163) 6588 404.8 1.6e-111
XP_006715666 (OMIM: 603473) PREDICTED: serine/thre ( 886) 5893 363.8 2.7e-99
XP_016866970 (OMIM: 603473) PREDICTED: serine/thre ( 850) 5869 362.3 6.9e-99
XP_016866965 (OMIM: 603473) PREDICTED: serine/thre (1058) 5829 360.0 4.2e-98
XP_016866969 (OMIM: 603473) PREDICTED: serine/thre ( 883) 4686 292.7 6.7e-78
NP_001257448 (OMIM: 603473) serine/threonine-prote ( 690) 4596 287.3 2.2e-76
XP_016866971 (OMIM: 603473) PREDICTED: serine/thre ( 672) 4592 287.0 2.5e-76
XP_016876030 (OMIM: 604861) PREDICTED: serine/thre ( 981) 2830 183.4 5.9e-45
XP_011533344 (OMIM: 604861) PREDICTED: serine/thre (1001) 2830 183.4 6e-45
NP_055387 (OMIM: 604861) serine/threonine-protein (1088) 2830 183.4 6.4e-45
XP_005266399 (OMIM: 604861) PREDICTED: serine/thre (1088) 2830 183.4 6.4e-45
XP_016876031 (OMIM: 604861) PREDICTED: serine/thre ( 906) 1944 131.2 2.8e-29
XP_016865715 (OMIM: 606964) PREDICTED: serine/thre ( 439) 792 63.1 4.4e-09
NP_055815 (OMIM: 615836) serine/threonine-protein ( 464) 792 63.1 4.5e-09
XP_006719121 (OMIM: 615836) PREDICTED: serine/thre ( 464) 792 63.1 4.5e-09
XP_016874525 (OMIM: 615836) PREDICTED: serine/thre ( 464) 792 63.1 4.5e-09
XP_006715051 (OMIM: 606964) PREDICTED: serine/thre ( 465) 792 63.1 4.5e-09
NP_009202 (OMIM: 606964) serine/threonine-protein ( 465) 792 63.1 4.5e-09
NP_001292031 (OMIM: 606964) serine/threonine-prote ( 465) 792 63.1 4.5e-09
XP_006715052 (OMIM: 606964) PREDICTED: serine/thre ( 465) 792 63.1 4.5e-09
XP_006719122 (OMIM: 615836) PREDICTED: serine/thre ( 412) 734 59.6 4.4e-08
XP_005253399 (OMIM: 615836) PREDICTED: serine/thre ( 423) 633 53.7 2.8e-06
XP_011518915 (OMIM: 615836) PREDICTED: serine/thre ( 371) 625 53.2 3.5e-06
NP_001275695 (OMIM: 160900,605377) myotonin-protei ( 530) 559 49.4 6.8e-05
NP_001075029 (OMIM: 160900,605377) myotonin-protei ( 624) 559 49.5 7.7e-05
NP_001075031 (OMIM: 160900,605377) myotonin-protei ( 625) 559 49.5 7.7e-05
NP_004400 (OMIM: 160900,605377) myotonin-protein k ( 629) 559 49.5 7.8e-05
NP_001075032 (OMIM: 160900,605377) myotonin-protei ( 639) 541 48.4 0.00016
NP_001275693 (OMIM: 160900,605377) myotonin-protei ( 655) 541 48.4 0.00017
XP_016873487 (OMIM: 613991) PREDICTED: serine/thre (1081) 531 48.0 0.00037
XP_011543463 (OMIM: 613991) PREDICTED: serine/thre (1135) 531 48.0 0.00038
XP_016873486 (OMIM: 613991) PREDICTED: serine/thre (1139) 531 48.0 0.00038
XP_011543461 (OMIM: 613991) PREDICTED: serine/thre (1481) 531 48.1 0.00047
XP_011543460 (OMIM: 613991) PREDICTED: serine/thre (1495) 531 48.1 0.00047
XP_011543459 (OMIM: 613991) PREDICTED: serine/thre (1530) 531 48.1 0.00048
NP_059995 (OMIM: 613991) serine/threonine-protein (1551) 531 48.1 0.00048
XP_011543458 (OMIM: 613991) PREDICTED: serine/thre (1562) 531 48.1 0.00049
XP_016873485 (OMIM: 613991) PREDICTED: serine/thre (1568) 531 48.1 0.00049
XP_011543457 (OMIM: 613991) PREDICTED: serine/thre (1569) 531 48.1 0.00049
NP_005397 (OMIM: 601702) rho-associated protein ki (1354) 528 47.9 0.00049
XP_016858071 (OMIM: 603412) PREDICTED: serine/thre (1589) 527 47.9 0.00058
NP_055641 (OMIM: 603412) serine/threonine-protein (1638) 527 47.9 0.0006
NP_003598 (OMIM: 603412) serine/threonine-protein (1719) 527 47.9 0.00062
XP_005273381 (OMIM: 603412) PREDICTED: serine/thre (1732) 527 47.9 0.00062
>>NP_004681 (OMIM: 603473) serine/threonine-protein kina (1130 aa)
initn: 7771 init1: 7771 opt: 7771 Z-score: 2500.0 bits: 474.5 E(85289): 1.6e-132
Smith-Waterman score: 7771; 100.0% identity (100.0% similar) in 1130 aa overlap (1-1130:1-1130)
10 20 30 40 50 60
pF1KE3 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 KVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 QQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KE3 RRFFDDNGYPYNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RRFFDDNGYPYNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV
1090 1100 1110 1120 1130
>>XP_016866967 (OMIM: 603473) PREDICTED: serine/threonin (1025 aa)
initn: 7012 init1: 7012 opt: 7012 Z-score: 2259.0 bits: 429.7 E(85289): 4.3e-119
Smith-Waterman score: 7012; 99.9% identity (100.0% similar) in 1015 aa overlap (116-1130:11-1025)
90 100 110 120 130 140
pF1KE3 LPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVIQALQKTNNRSIEAAIEFISKMSYQD
.:::::::::::::::::::::::::::::
XP_016 MSFEILNPLGQDMVIQALQKTNNRSIEAAIEFISKMSYQD
10 20 30 40
150 160 170 180 190 200
pF1KE3 PRREQMAAAAARPINASMKPGNVQQSVNRKQSWKGSKESLVPQRHGPPLGESVAYHSESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRREQMAAAAARPINASMKPGNVQQSVNRKQSWKGSKESLVPQRHGPPLGESVAYHSESP
50 60 70 80 90 100
210 220 230 240 250 260
pF1KE3 NSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPP
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE3 PSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPV
170 180 190 200 210 220
330 340 350 360 370 380
pF1KE3 GRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNRQPPPPYPLTAANGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNRQPPPPYPLTAANGQS
230 240 250 260 270 280
390 400 410 420 430 440
pF1KE3 PSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNMELYNISVPGLQTNWPQSSSAPAQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNMELYNISVPGLQTNWPQSSSAPAQSSP
290 300 310 320 330 340
450 460 470 480 490 500
pF1KE3 SSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAITPAPIQQPVKSMRVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAITPAPIQQPVKSMRVLK
350 360 370 380 390 400
510 520 530 540 550 560
pF1KE3 PELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAPNYQGPPPPYPKHLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAPNYQGPPPPYPKHLLH
410 420 430 440 450 460
570 580 590 600 610 620
pF1KE3 QNPSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNPSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDEE
470 480 490 500 510 520
630 640 650 660 670 680
pF1KE3 RRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKML
530 540 550 560 570 580
690 700 710 720 730 740
pF1KE3 CQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRN
590 600 610 620 630 640
750 760 770 780 790 800
pF1KE3 QVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLA
650 660 670 680 690 700
810 820 830 840 850 860
pF1KE3 RFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSG
710 720 730 740 750 760
870 880 890 900 910 920
pF1KE3 DHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRT
770 780 790 800 810 820
930 940 950 960 970 980
pF1KE3 GYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLI
830 840 850 860 870 880
990 1000 1010 1020 1030 1040
pF1KE3 IKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPD
890 900 910 920 930 940
1050 1060 1070 1080 1090 1100
pF1KE3 KLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQ
950 960 970 980 990 1000
1110 1120 1130
pF1KE3 GSEQQSDEDDQNTGSEIKNRDLVYV
:::::::::::::::::::::::::
XP_016 GSEQQSDEDDQNTGSEIKNRDLVYV
1010 1020
>>XP_016866968 (OMIM: 603473) PREDICTED: serine/threonin (993 aa)
initn: 6683 init1: 6592 opt: 6594 Z-score: 2126.1 bits: 405.1 E(85289): 1.1e-111
Smith-Waterman score: 6600; 97.9% identity (98.4% similar) in 988 aa overlap (1-977:1-988)
10 20 30 40 50 60
pF1KE3 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
910 920 930 940 950 960
970 980 990 1000
pF1KE3 K----------VIN-WQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPF
: :.: : ..:.: :.
XP_016 KIWGFTMLPRLVLNFWAQAIHLPRPPKVLGLQV
970 980 990
>>XP_011534554 (OMIM: 603473) PREDICTED: serine/threonin (1001 aa)
initn: 6588 init1: 6588 opt: 6588 Z-score: 2124.2 bits: 404.7 E(85289): 1.4e-111
Smith-Waterman score: 6588; 100.0% identity (100.0% similar) in 961 aa overlap (1-961:1-961)
10 20 30 40 50 60
pF1KE3 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 KVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLR
:
XP_011 KDLEVAASCILTRFYSCLLWEGDRRVYVVHLPQNWDLSGCF
970 980 990 1000
>>XP_016866966 (OMIM: 603473) PREDICTED: serine/threonin (1034 aa)
initn: 6588 init1: 6588 opt: 6588 Z-score: 2124.0 bits: 404.7 E(85289): 1.4e-111
Smith-Waterman score: 6588; 100.0% identity (100.0% similar) in 961 aa overlap (1-961:1-961)
10 20 30 40 50 60
pF1KE3 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 KVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLR
:
XP_016 KPGMVAHTCNPSALEGHSRKNTGTQEFEIGLGNIDLEVAASCILTRFYSCLLWEGDRRVY
970 980 990 1000 1010 1020
>>XP_016866964 (OMIM: 603473) PREDICTED: serine/threonin (1163 aa)
initn: 7757 init1: 6588 opt: 6588 Z-score: 2123.3 bits: 404.8 E(85289): 1.6e-111
Smith-Waterman score: 7695; 97.2% identity (97.2% similar) in 1163 aa overlap (1-1130:1-1163)
10 20 30 40 50 60
pF1KE3 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
910 920 930 940 950 960
970 980
pF1KE3 K---------------------------------VINWQTSLHIPPQAKLSPEASDLIIK
: ::::::::::::::::::::::::::
XP_016 KPGMVAHTCNPSALEGHSRKNTGTQEFEIGLGNIVINWQTSLHIPPQAKLSPEASDLIIK
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE3 LCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKL
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE3 WSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQGS
1090 1100 1110 1120 1130 1140
1110 1120 1130
pF1KE3 EQQSDEDDQNTGSEIKNRDLVYV
:::::::::::::::::::::::
XP_016 EQQSDEDDQNTGSEIKNRDLVYV
1150 1160
>>XP_016866963 (OMIM: 603473) PREDICTED: serine/threonin (1163 aa)
initn: 7757 init1: 6588 opt: 6588 Z-score: 2123.3 bits: 404.8 E(85289): 1.6e-111
Smith-Waterman score: 7695; 97.2% identity (97.2% similar) in 1163 aa overlap (1-1130:1-1163)
10 20 30 40 50 60
pF1KE3 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
910 920 930 940 950 960
970 980
pF1KE3 K---------------------------------VINWQTSLHIPPQAKLSPEASDLIIK
: ::::::::::::::::::::::::::
XP_016 KPGMVAHTCNPSALEGHSRKNTGTQEFEIGLGNIVINWQTSLHIPPQAKLSPEASDLIIK
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE3 LCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKL
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE3 WSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQGS
1090 1100 1110 1120 1130 1140
1110 1120 1130
pF1KE3 EQQSDEDDQNTGSEIKNRDLVYV
:::::::::::::::::::::::
XP_016 EQQSDEDDQNTGSEIKNRDLVYV
1150 1160
>>XP_006715666 (OMIM: 603473) PREDICTED: serine/threonin (886 aa)
initn: 5893 init1: 5893 opt: 5893 Z-score: 1903.7 bits: 363.8 E(85289): 2.7e-99
Smith-Waterman score: 5893; 100.0% identity (100.0% similar) in 865 aa overlap (1-865:1-865)
10 20 30 40 50 60
pF1KE3 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
:::::::::::::::::::::::::
XP_006 HIKLTDFGLCTGFRWTHDSKYYQSGPMLFLLHHTASPRSLQALMEV
850 860 870 880
>>XP_016866970 (OMIM: 603473) PREDICTED: serine/threonin (850 aa)
initn: 5869 init1: 5869 opt: 5869 Z-score: 1896.3 bits: 362.3 E(85289): 6.9e-99
Smith-Waterman score: 5869; 100.0% identity (100.0% similar) in 850 aa overlap (281-1130:1-850)
260 270 280 290 300 310
pF1KE3 PRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPM
::::::::::::::::::::::::::::::
XP_016 MEYVISRISPVPPGAWQEGYPPPPLNTSPM
10 20 30
320 330 340 350 360 370
pF1KE3 NPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNR
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE3 QPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNMELYNISVPGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNMELYNISVPGLQ
100 110 120 130 140 150
440 450 460 470 480 490
pF1KE3 TNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAIT
160 170 180 190 200 210
500 510 520 530 540 550
pF1KE3 PAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAP
220 230 240 250 260 270
560 570 580 590 600 610
pF1KE3 NYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQI
280 290 300 310 320 330
620 630 640 650 660 670
pF1KE3 TTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMR
340 350 360 370 380 390
680 690 700 710 720 730
pF1KE3 VGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKAL
400 410 420 430 440 450
740 750 760 770 780 790
pF1KE3 YATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDM
460 470 480 490 500 510
800 810 820 830 840 850
pF1KE3 MSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLC
520 530 540 550 560 570
860 870 880 890 900 910
pF1KE3 TGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSL
580 590 600 610 620 630
920 930 940 950 960 970
pF1KE3 VGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLH
640 650 660 670 680 690
980 990 1000 1010 1020 1030
pF1KE3 IPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKI
700 710 720 730 740 750
1040 1050 1060 1070 1080 1090
pF1KE3 THPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYP
760 770 780 790 800 810
1100 1110 1120 1130
pF1KE3 YNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV
::::::::::::::::::::::::::::::::::::::::
XP_016 YNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV
820 830 840 850
>>XP_016866965 (OMIM: 603473) PREDICTED: serine/threonin (1058 aa)
initn: 6998 init1: 5829 opt: 5829 Z-score: 1882.3 bits: 360.0 E(85289): 4.2e-98
Smith-Waterman score: 6936; 96.8% identity (96.9% similar) in 1048 aa overlap (116-1130:11-1058)
90 100 110 120 130 140
pF1KE3 LPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVIQALQKTNNRSIEAAIEFISKMSYQD
.:::::::::::::::::::::::::::::
XP_016 MSFEILNPLGQDMVIQALQKTNNRSIEAAIEFISKMSYQD
10 20 30 40
150 160 170 180 190 200
pF1KE3 PRREQMAAAAARPINASMKPGNVQQSVNRKQSWKGSKESLVPQRHGPPLGESVAYHSESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRREQMAAAAARPINASMKPGNVQQSVNRKQSWKGSKESLVPQRHGPPLGESVAYHSESP
50 60 70 80 90 100
210 220 230 240 250 260
pF1KE3 NSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPP
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE3 PSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPV
170 180 190 200 210 220
330 340 350 360 370 380
pF1KE3 GRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNRQPPPPYPLTAANGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNRQPPPPYPLTAANGQS
230 240 250 260 270 280
390 400 410 420 430 440
pF1KE3 PSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNMELYNISVPGLQTNWPQSSSAPAQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNMELYNISVPGLQTNWPQSSSAPAQSSP
290 300 310 320 330 340
450 460 470 480 490 500
pF1KE3 SSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAITPAPIQQPVKSMRVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAITPAPIQQPVKSMRVLK
350 360 370 380 390 400
510 520 530 540 550 560
pF1KE3 PELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAPNYQGPPPPYPKHLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAPNYQGPPPPYPKHLLH
410 420 430 440 450 460
570 580 590 600 610 620
pF1KE3 QNPSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNPSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDEE
470 480 490 500 510 520
630 640 650 660 670 680
pF1KE3 RRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKML
530 540 550 560 570 580
690 700 710 720 730 740
pF1KE3 CQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRN
590 600 610 620 630 640
750 760 770 780 790 800
pF1KE3 QVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLA
650 660 670 680 690 700
810 820 830 840 850 860
pF1KE3 RFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSG
710 720 730 740 750 760
870 880 890 900 910 920
pF1KE3 DHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRT
770 780 790 800 810 820
930 940 950 960
pF1KE3 GYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMK------------------------
::::::::::::::::::::::::::::::::::::
XP_016 GYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKPGMVAHTCNPSALEGHSRKNTGTQ
830 840 850 860 870 880
970 980 990 1000 1010
pF1KE3 ---------VINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKT
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFEIGLGNIVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKT
890 900 910 920 930 940
1020 1030 1040 1050 1060 1070
pF1KE3 IDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPE
950 960 970 980 990 1000
1080 1090 1100 1110 1120 1130
pF1KE3 HAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV
1010 1020 1030 1040 1050
1130 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:41:31 2016 done: Sun Nov 6 01:41:33 2016
Total Scan time: 16.420 Total Display time: 0.520
Function used was FASTA [36.3.4 Apr, 2011]