Result of FASTA (omim) for
pF1KE3386
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3386, 1207 aa
1>>>pF1KE3386 1207 - 1207 aa - 1207 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6348+/-0.000491; mu= 22.6391+/- 0.030
mean_var=187.8296+/-37.603, 0's: 0 Z-trim(113.6): 443 B-trim: 36 in 1/57
Lambda= 0.093582
statistics sampled from 22444 (22957) to 22444 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.269), width: 16
Scan time: 14.370
The best scores are: opt bits E(85289)
NP_001954 (OMIM: 131530,611718) pro-epidermal grow (1207) 8547 1168.7 0
XP_005262853 (OMIM: 131530,611718) PREDICTED: pro- (1215) 8521 1165.2 0
XP_016863335 (OMIM: 131530,611718) PREDICTED: pro- (1215) 8521 1165.2 0
XP_016863334 (OMIM: 131530,611718) PREDICTED: pro- (1223) 8495 1161.7 0
XP_011530009 (OMIM: 131530,611718) PREDICTED: pro- (1178) 8233 1126.3 0
XP_016863339 (OMIM: 131530,611718) PREDICTED: pro- (1141) 7734 1058.9 0
NP_001171601 (OMIM: 131530,611718) pro-epidermal g (1166) 6407 879.7 0
XP_016863336 (OMIM: 131530,611718) PREDICTED: pro- (1182) 6381 876.2 0
XP_016863342 (OMIM: 131530,611718) PREDICTED: pro- ( 934) 6372 874.9 0
NP_001171602 (OMIM: 131530,611718) pro-epidermal g (1165) 6214 853.7 0
XP_016863337 (OMIM: 131530,611718) PREDICTED: pro- (1181) 6188 850.2 0
XP_016863340 (OMIM: 131530,611718) PREDICTED: pro- (1060) 5828 801.5 0
XP_016863338 (OMIM: 131530,611718) PREDICTED: pro- (1142) 5828 801.5 0
XP_016863344 (OMIM: 131530,611718) PREDICTED: pro- ( 696) 4753 656.1 2.3e-187
XP_016863343 (OMIM: 131530,611718) PREDICTED: pro- ( 711) 4740 654.3 7.8e-187
XP_016863341 (OMIM: 131530,611718) PREDICTED: pro- (1010) 3521 490.0 3.3e-137
XP_011518405 (OMIM: 212780,604270,614305,616304) P (1637) 1062 158.3 3.7e-37
XP_016873223 (OMIM: 212780,604270,614305,616304) P (1809) 1062 158.4 3.9e-37
NP_002325 (OMIM: 212780,604270,614305,616304) low- (1905) 1062 158.4 4e-37
NP_002323 (OMIM: 107770) prolow-density lipoprotei (4544) 966 146.1 5e-33
XP_016874792 (OMIM: 107770) PREDICTED: prolow-dens (4561) 966 146.1 5e-33
XP_005271231 (OMIM: 602600,608446) PREDICTED: low- ( 847) 890 134.7 2.5e-30
XP_011540397 (OMIM: 602600,608446) PREDICTED: low- ( 804) 885 134.0 3.9e-30
XP_011540398 (OMIM: 602600,608446) PREDICTED: low- ( 762) 882 133.5 5.1e-30
XP_016857755 (OMIM: 602600,608446) PREDICTED: low- ( 842) 882 133.6 5.3e-30
XP_006710945 (OMIM: 602600,608446) PREDICTED: low- ( 901) 882 133.6 5.5e-30
XP_006710944 (OMIM: 602600,608446) PREDICTED: low- ( 917) 882 133.6 5.6e-30
XP_005271230 (OMIM: 602600,608446) PREDICTED: low- ( 976) 882 133.7 5.8e-30
NP_150643 (OMIM: 602600,608446) low-density lipopr ( 793) 878 133.0 7.5e-30
NP_059992 (OMIM: 602600,608446) low-density lipopr ( 700) 875 132.5 9.3e-30
NP_001018064 (OMIM: 602600,608446) low-density lip ( 904) 876 132.8 9.7e-30
NP_004622 (OMIM: 602600,608446) low-density lipopr ( 963) 876 132.9 1e-29
XP_005271232 (OMIM: 602600,608446) PREDICTED: low- ( 834) 875 132.6 1e-29
XP_011543333 (OMIM: 133780,144750,166710,259770,60 (1600) 854 130.2 1e-28
XP_016874793 (OMIM: 603507,610947,616724) PREDICTE (1345) 853 130.0 1e-28
NP_002326 (OMIM: 133780,144750,166710,259770,60181 (1615) 854 130.2 1e-28
XP_011543332 (OMIM: 133780,144750,166710,259770,60 (1624) 854 130.2 1e-28
XP_005274051 (OMIM: 133780,144750,166710,259770,60 (1653) 854 130.3 1e-28
XP_011543331 (OMIM: 133780,144750,166710,259770,60 (1662) 854 130.3 1e-28
XP_011518973 (OMIM: 603507,610947,616724) PREDICTE (1462) 853 130.0 1.1e-28
NP_002327 (OMIM: 603507,610947,616724) low-density (1613) 853 130.1 1.1e-28
XP_006719141 (OMIM: 603507,610947,616724) PREDICTE (1613) 853 130.1 1.1e-28
XP_011509485 (OMIM: 222448,600073) PREDICTED: low- (4612) 831 127.9 1.5e-27
XP_011540396 (OMIM: 602600,608446) PREDICTED: low- ( 934) 815 124.6 3e-27
XP_011509486 (OMIM: 222448,600073) PREDICTED: low- (3892) 818 126.0 4.8e-27
NP_004516 (OMIM: 222448,600073) low-density lipopr (4655) 818 126.1 5.2e-27
NP_001182728 (OMIM: 143890,606945) low-density lip ( 819) 802 122.8 9.4e-27
XP_011526312 (OMIM: 143890,606945) PREDICTED: low- ( 834) 802 122.8 9.5e-27
NP_001182727 (OMIM: 143890,606945) low-density lip ( 858) 802 122.8 9.6e-27
NP_000518 (OMIM: 143890,606945) low-density lipopr ( 860) 802 122.8 9.6e-27
>>NP_001954 (OMIM: 131530,611718) pro-epidermal growth f (1207 aa)
initn: 8547 init1: 8547 opt: 8547 Z-score: 6250.9 bits: 1168.7 E(85289): 0
Smith-Waterman score: 8547; 99.8% identity (99.9% similar) in 1207 aa overlap (1-1207:1-1207)
10 20 30 40 50 60
pF1KE3 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNEC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNKRTGKDRVR
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 LALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 SMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 EGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 EGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 GTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPP
1150 1160 1170 1180 1190 1200
pF1KE3 HQMELTQ
:::::::
NP_001 HQMELTQ
>>XP_005262853 (OMIM: 131530,611718) PREDICTED: pro-epid (1215 aa)
initn: 7939 init1: 7939 opt: 8521 Z-score: 6231.9 bits: 1165.2 E(85289): 0
Smith-Waterman score: 8521; 99.2% identity (99.3% similar) in 1215 aa overlap (1-1207:1-1215)
10 20 30 40 50 60
pF1KE3 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNEC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNKRTGKDRVR
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_005 AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 LALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 SMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 EGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_005 EGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KE3 RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADG--------SMQPTSWR
:::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_005 RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGQFLSLAPGSMQPTSWR
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE3 QEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLW
1150 1160 1170 1180 1190 1200
1200
pF1KE3 QQRALDPPHQMELTQ
:::::::::::::::
XP_005 QQRALDPPHQMELTQ
1210
>>XP_016863335 (OMIM: 131530,611718) PREDICTED: pro-epid (1215 aa)
initn: 8533 init1: 8266 opt: 8521 Z-score: 6231.9 bits: 1165.2 E(85289): 0
Smith-Waterman score: 8521; 99.2% identity (99.3% similar) in 1215 aa overlap (1-1207:1-1215)
10 20 30 40 50
pF1KE3 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCV--------GPAPFLIFSH
:::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVVWSLSSHPGPAPFLIFSH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNK
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 GGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 GGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICP
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 DSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERC
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 QYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYE
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE3 ESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWR
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE3 QEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLW
1150 1160 1170 1180 1190 1200
1200
pF1KE3 QQRALDPPHQMELTQ
:::::::::::::::
XP_016 QQRALDPPHQMELTQ
1210
>>XP_016863334 (OMIM: 131530,611718) PREDICTED: pro-epid (1223 aa)
initn: 7925 init1: 7658 opt: 8495 Z-score: 6212.9 bits: 1161.7 E(85289): 0
Smith-Waterman score: 8495; 98.5% identity (98.6% similar) in 1223 aa overlap (1-1207:1-1223)
10 20 30 40 50
pF1KE3 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCV--------GPAPFLIFSH
:::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVVWSLSSHPGPAPFLIFSH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNK
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 GGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 GGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICP
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 DSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERC
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 QYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYE
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120
pF1KE3 ESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADG--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGQFLSLAPG
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 SMQPTSWRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMQPTSWRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHS
1150 1160 1170 1180 1190 1200
1190 1200
pF1KE3 LLSANPLWQQRALDPPHQMELTQ
:::::::::::::::::::::::
XP_016 LLSANPLWQQRALDPPHQMELTQ
1210 1220
>>XP_011530009 (OMIM: 131530,611718) PREDICTED: pro-epid (1178 aa)
initn: 7650 init1: 7650 opt: 8233 Z-score: 6021.9 bits: 1126.3 E(85289): 0
Smith-Waterman score: 8233; 98.9% identity (99.1% similar) in 1176 aa overlap (40-1207:5-1178)
10 20 30 40 50 60
pF1KE3 PVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRIDTEGTNYEQL
.: ::::::::::::::::::::::::::
XP_011 MAKISC--PAPFLIFSHGNSIFRIDTEGTNYEQL
10 20 30
70 80 90 100 110 120
pF1KE3 VVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSGMAINWINEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSGMAINWINEE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 VIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAGSLYRADLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAGSLYRADLDG
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 VGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHISKHPTQHNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHISKHPTQHNL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 FAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 TWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE3 GCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE3 ERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASGPQPFLLFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASGPQPFLLFAN
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE3 SQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERANMDGSQRERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERANMDGSQRERL
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE3 IEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQPRGIAVHPMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQPRGIAVHPMA
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE3 KRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCDAKQSVIEMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCDAKQSVIEMA
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE3 NLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNKRTGKDRVRLQGSMLKPS
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
XP_011 NLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVRLQGSMLKPS
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE3 SLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE3 AGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISE
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE3 GEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIH
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE3 CLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHLREDDHHYSV
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHLREDDHHYSV
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE3 RNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELRHAGHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELRHAGHGQ
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE3 QQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRSRRPADTEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRSRRPADTEDG
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE3 MSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADG--------SMQPTSWRQEPQLCGMG
::::::::::::::::::::::::::::::::::: :::::::::::::::::
XP_011 MSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGQFLSLAPGSMQPTSWRQEPQLCGMG
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE3 TEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPPH
1120 1130 1140 1150 1160 1170
pF1KE3 QMELTQ
::::::
XP_011 QMELTQ
>>XP_016863339 (OMIM: 131530,611718) PREDICTED: pro-epid (1141 aa)
initn: 7741 init1: 7474 opt: 7734 Z-score: 5657.9 bits: 1058.9 E(85289): 0
Smith-Waterman score: 7734; 97.0% identity (97.9% similar) in 1137 aa overlap (1-1128:1-1133)
10 20 30 40 50
pF1KE3 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCV--------GPAPFLIFSH
:::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVVWSLSSHPGPAPFLIFSH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNK
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 GGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 GGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICP
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 DSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERC
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 QYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYE
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE3 ESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQA-ADGSMQPTSW
::::::::::::::::::::::::: . ..:..: .: : .:. : : . :
XP_016 ESSRDVRSRRPADTEDGMSSCPQPW----GQCNQLHGGRSPSYVEWAQSKAAGFQYPVIR
1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KE3 RQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPL
XP_016 APVPR
1140
>>NP_001171601 (OMIM: 131530,611718) pro-epidermal growt (1166 aa)
initn: 6404 init1: 6404 opt: 6407 Z-score: 4689.6 bits: 879.7 E(85289): 0
Smith-Waterman score: 8154; 96.5% identity (96.6% similar) in 1207 aa overlap (1-1207:1-1166)
10 20 30 40 50 60
pF1KE3 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNEC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNKRTGKDRVR
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 LALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 SMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 EGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
:::::::::::: :::::::
NP_001 EGYQGDGIHCLD-----------------------------------------STPPPHL
910
970 980 990 1000 1010 1020
pF1KE3 REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KE3 ELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KE3 RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGM
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KE3 GTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPP
1100 1110 1120 1130 1140 1150
pF1KE3 HQMELTQ
:::::::
NP_001 HQMELTQ
1160
>>XP_016863336 (OMIM: 131530,611718) PREDICTED: pro-epid (1182 aa)
initn: 7007 init1: 6123 opt: 6381 Z-score: 4670.6 bits: 876.2 E(85289): 0
Smith-Waterman score: 8102; 95.3% identity (95.3% similar) in 1223 aa overlap (1-1207:1-1182)
10 20 30 40 50
pF1KE3 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCV--------GPAPFLIFSH
:::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVVWSLSSHPGPAPFLIFSH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNK
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 GGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICP
::::::::::::::::::::
XP_016 GGYVCRCSEGYQGDGIHCLD----------------------------------------
910 920
960 970 980 990 1000 1010
pF1KE3 DSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -STPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERC
930 940 950 960 970
1020 1030 1040 1050 1060 1070
pF1KE3 QYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYE
980 990 1000 1010 1020 1030
1080 1090 1100 1110 1120
pF1KE3 ESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADG--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGQFLSLAPG
1040 1050 1060 1070 1080 1090
1130 1140 1150 1160 1170 1180
pF1KE3 SMQPTSWRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMQPTSWRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHS
1100 1110 1120 1130 1140 1150
1190 1200
pF1KE3 LLSANPLWQQRALDPPHQMELTQ
:::::::::::::::::::::::
XP_016 LLSANPLWQQRALDPPHQMELTQ
1160 1170 1180
>>XP_016863342 (OMIM: 131530,611718) PREDICTED: pro-epid (934 aa)
initn: 6616 init1: 6117 opt: 6372 Z-score: 4665.0 bits: 874.9 E(85289): 0
Smith-Waterman score: 6372; 98.8% identity (99.0% similar) in 921 aa overlap (1-913:1-921)
10 20 30 40 50
pF1KE3 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCV--------GPAPFLIFSH
:::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVVWSLSSHPGPAPFLIFSH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKII
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 TDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNK
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFM
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQ
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTE
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 GGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICP
::::::::::::::::::: .
XP_016 GGYVCRCSEGYQGDGIHCLAVLLATSGSDVSTET
910 920 930
>>NP_001171602 (OMIM: 131530,611718) pro-epidermal growt (1165 aa)
initn: 6132 init1: 6132 opt: 6214 Z-score: 4548.8 bits: 853.7 E(85289): 0
Smith-Waterman score: 8146; 96.4% identity (96.4% similar) in 1207 aa overlap (1-1207:1-1165)
10 20 30 40 50 60
pF1KE3 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNEC
::::::::::::: :::::
NP_001 LAQPKAEDDTWEP------------------------------------------DVNEC
310
370 380 390 400 410 420
pF1KE3 AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPL
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE3 CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASG
380 390 400 410 420 430
490 500 510 520 530 540
pF1KE3 PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
440 450 460 470 480 490
550 560 570 580 590 600
pF1KE3 MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
500 510 520 530 540 550
610 620 630 640 650 660
pF1KE3 RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
560 570 580 590 600 610
670 680 690 700 710 720
pF1KE3 AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNKRTGKDRVR
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVR
620 630 640 650 660 670
730 740 750 760 770 780
pF1KE3 LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
680 690 700 710 720 730
790 800 810 820 830 840
pF1KE3 LALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
740 750 760 770 780 790
850 860 870 880 890 900
pF1KE3 SMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
800 810 820 830 840 850
910 920 930 940 950 960
pF1KE3 EGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 EGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KE3 REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KE3 ELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KE3 RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGM
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KE3 GTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPP
1100 1110 1120 1130 1140 1150
pF1KE3 HQMELTQ
:::::::
NP_001 HQMELTQ
1160
1207 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:29:37 2016 done: Tue Nov 8 16:29:39 2016
Total Scan time: 14.370 Total Display time: 0.490
Function used was FASTA [36.3.4 Apr, 2011]