FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3388, 1214 aa 1>>>pF1KE3388 1214 - 1214 aa - 1214 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.6845+/-0.000385; mu= 3.9579+/- 0.024 mean_var=280.1619+/-57.529, 0's: 0 Z-trim(121.7): 158 B-trim: 0 in 0/60 Lambda= 0.076625 statistics sampled from 38450 (38612) to 38450 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.453), width: 16 Scan time: 16.570 The best scores are: opt bits E(85289) NP_690618 (OMIM: 601826) diacylglycerol kinase del (1214) 8177 918.4 0 XP_011510332 (OMIM: 601826) PREDICTED: diacylglyce (1171) 7811 877.9 0 XP_016860627 (OMIM: 601826) PREDICTED: diacylglyce (1174) 7809 877.7 0 NP_003639 (OMIM: 601826) diacylglycerol kinase del (1170) 7807 877.4 0 XP_011510330 (OMIM: 601826) PREDICTED: diacylglyce (1238) 7806 877.4 0 XP_011510333 (OMIM: 601826) PREDICTED: diacylglyce (1156) 7770 873.4 0 XP_011510334 (OMIM: 601826) PREDICTED: diacylglyce (1156) 7770 873.4 0 XP_016860628 (OMIM: 601826) PREDICTED: diacylglyce (1141) 7427 835.4 0 XP_005246164 (OMIM: 601826) PREDICTED: diacylglyce (1102) 7413 833.9 0 XP_011510331 (OMIM: 601826) PREDICTED: diacylglyce (1211) 7315 823.1 0 XP_005246165 (OMIM: 601826) PREDICTED: diacylglyce (1081) 7295 820.8 0 XP_011510337 (OMIM: 601826) PREDICTED: diacylglyce (1081) 7295 820.8 0 XP_011510339 (OMIM: 601826) PREDICTED: diacylglyce (1081) 7295 820.8 0 XP_011510342 (OMIM: 601826) PREDICTED: diacylglyce (1081) 7295 820.8 0 XP_016860629 (OMIM: 601826) PREDICTED: diacylglyce (1081) 7295 820.8 0 XP_011510335 (OMIM: 601826) PREDICTED: diacylglyce (1132) 6793 765.3 0 XP_011510341 (OMIM: 601826) PREDICTED: diacylglyce ( 968) 6009 678.6 5.2e-194 NP_821077 (OMIM: 604071) diacylglycerol kinase eta (1220) 4982 565.2 9.3e-160 NP_690874 (OMIM: 604071) diacylglycerol kinase eta (1164) 4621 525.2 9.3e-148 NP_001191433 (OMIM: 604071) diacylglycerol kinase (1164) 4621 525.2 9.3e-148 NP_001191435 (OMIM: 604071) diacylglycerol kinase (1084) 4613 524.3 1.6e-147 XP_005246167 (OMIM: 601826) PREDICTED: diacylglyce ( 680) 4529 514.9 7.2e-145 NP_001191434 (OMIM: 604071) diacylglycerol kinase (1100) 4487 510.4 2.6e-143 NP_001284358 (OMIM: 604071) diacylglycerol kinase ( 919) 3284 377.4 2.4e-103 XP_016884757 (OMIM: 300837) PREDICTED: diacylglyce (1242) 1024 127.6 4.9e-28 NP_001013764 (OMIM: 300837) diacylglycerol kinase (1271) 1022 127.4 5.8e-28 NP_001337 (OMIM: 601854) diacylglycerol kinase gam ( 791) 609 81.6 2.3e-14 NP_001074214 (OMIM: 601854) diacylglycerol kinase ( 752) 471 66.3 8.5e-10 XP_016874398 (OMIM: 125855) PREDICTED: diacylglyce ( 594) 466 65.7 1e-09 XP_005268746 (OMIM: 125855) PREDICTED: diacylglyce ( 623) 466 65.7 1.1e-09 XP_005268747 (OMIM: 125855) PREDICTED: diacylglyce ( 623) 466 65.7 1.1e-09 XP_011536297 (OMIM: 125855) PREDICTED: diacylglyce ( 623) 466 65.7 1.1e-09 XP_011518725 (OMIM: 601441) PREDICTED: diacylglyce ( 809) 468 66.0 1.1e-09 NP_958853 (OMIM: 125855) diacylglycerol kinase alp ( 735) 466 65.8 1.2e-09 XP_011536293 (OMIM: 125855) PREDICTED: diacylglyce ( 735) 466 65.8 1.2e-09 NP_963848 (OMIM: 125855) diacylglycerol kinase alp ( 735) 466 65.8 1.2e-09 NP_001336 (OMIM: 125855) diacylglycerol kinase alp ( 735) 466 65.8 1.2e-09 XP_011536295 (OMIM: 125855) PREDICTED: diacylglyce ( 735) 466 65.8 1.2e-09 NP_958852 (OMIM: 125855) diacylglycerol kinase alp ( 735) 466 65.8 1.2e-09 NP_001186197 (OMIM: 601441) diacylglycerol kinase ( 906) 468 66.1 1.2e-09 XP_011518724 (OMIM: 601441) PREDICTED: diacylglyce ( 911) 468 66.1 1.2e-09 NP_001186196 (OMIM: 601441) diacylglycerol kinase ( 928) 468 66.1 1.2e-09 NP_003637 (OMIM: 601441) diacylglycerol kinase zet ( 929) 468 66.1 1.2e-09 XP_006718418 (OMIM: 601441) PREDICTED: diacylglyce ( 933) 468 66.1 1.3e-09 NP_963291 (OMIM: 601441) diacylglycerol kinase zet ( 933) 468 66.1 1.3e-09 XP_005253239 (OMIM: 601441) PREDICTED: diacylglyce ( 934) 468 66.1 1.3e-09 NP_001186195 (OMIM: 601441) diacylglycerol kinase ( 934) 468 66.1 1.3e-09 NP_963290 (OMIM: 601441) diacylglycerol kinase zet ( 945) 468 66.1 1.3e-09 XP_005253238 (OMIM: 601441) PREDICTED: diacylglyce ( 946) 468 66.1 1.3e-09 XP_005268745 (OMIM: 125855) PREDICTED: diacylglyce ( 773) 466 65.8 1.3e-09 >>NP_690618 (OMIM: 601826) diacylglycerol kinase delta i (1214 aa) initn: 8177 init1: 8177 opt: 8177 Z-score: 4898.0 bits: 918.4 E(85289): 0 Smith-Waterman score: 8177; 100.0% identity (100.0% similar) in 1214 aa overlap (1-1214:1-1214) 10 20 30 40 50 60 pF1KE3 MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGML 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 TKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 TKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 CRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 CRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 REALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 REALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 GNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 GNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 LNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 LNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 LGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 LGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 ACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 ACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE3 EDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 EDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE3 VLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 VLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE3 QIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 QIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE3 PPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 PPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKIL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE3 YPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 YPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE3 NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE3 LNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 LNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE3 TVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 TVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCEL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE3 PRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 PRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE3 DRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 DRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMD 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE3 RQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 RQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE3 PVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 PVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILC 1150 1160 1170 1180 1190 1200 1210 pF1KE3 GIKELSRSAPAVEA :::::::::::::: NP_690 GIKELSRSAPAVEA 1210 >>XP_011510332 (OMIM: 601826) PREDICTED: diacylglycerol (1171 aa) initn: 7811 init1: 7811 opt: 7811 Z-score: 4679.5 bits: 877.9 E(85289): 0 Smith-Waterman score: 7811; 100.0% identity (100.0% similar) in 1163 aa overlap (52-1214:9-1171) 30 40 50 60 70 80 pF1KE3 EESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRT :::::::::::::::::::::::::::::: XP_011 MEVIAFPTKTIIKEGMLTKQNNSFQRSKRRYFKLRGRT 10 20 30 90 100 110 120 130 140 pF1KE3 LYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAAL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE3 KTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKA 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE3 HKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLR 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE3 LQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSP 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE3 LLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDG 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE3 SVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTK 340 350 360 370 380 390 450 460 470 480 490 500 pF1KE3 MLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVI 400 410 420 430 440 450 510 520 530 540 550 560 pF1KE3 SSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASS 460 470 480 490 500 510 570 580 590 600 610 620 pF1KE3 SLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIR 520 530 540 550 560 570 630 640 650 660 670 680 pF1KE3 QIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVS 580 590 600 610 620 630 690 700 710 720 730 740 pF1KE3 KSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRL 640 650 660 670 680 690 750 760 770 780 790 800 pF1KE3 LINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWY 700 710 720 730 740 750 810 820 830 840 850 860 pF1KE3 GVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDT 760 770 780 790 800 810 870 880 890 900 910 920 pF1KE3 FAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAW 820 830 840 850 860 870 930 940 950 960 970 980 pF1KE3 VQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQM 880 890 900 910 920 930 990 1000 1010 1020 1030 1040 pF1KE3 DQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEM 940 950 960 970 980 990 1050 1060 1070 1080 1090 1100 pF1KE3 VNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDE 1000 1010 1020 1030 1040 1050 1110 1120 1130 1140 1150 1160 pF1KE3 ESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCE 1060 1070 1080 1090 1100 1110 1170 1180 1190 1200 1210 pF1KE3 YKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA 1120 1130 1140 1150 1160 1170 >>XP_016860627 (OMIM: 601826) PREDICTED: diacylglycerol (1174 aa) initn: 7809 init1: 7809 opt: 7809 Z-score: 4678.3 bits: 877.7 E(85289): 0 Smith-Waterman score: 7809; 99.8% identity (100.0% similar) in 1164 aa overlap (51-1214:11-1174) 30 40 50 60 70 80 pF1KE3 PEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGR ..:::::::::::::::::::::::::::: XP_016 MGEPEVLTCYKQTIIKEGMLTKQNNSFQRSKRRYFKLRGR 10 20 30 40 90 100 110 120 130 140 pF1KE3 TLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAA 50 60 70 80 90 100 150 160 170 180 190 200 pF1KE3 LKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFK 110 120 130 140 150 160 210 220 230 240 250 260 pF1KE3 AHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVL 170 180 190 200 210 220 270 280 290 300 310 320 pF1KE3 RLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTS 230 240 250 260 270 280 330 340 350 360 370 380 pF1KE3 PLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGD 290 300 310 320 330 340 390 400 410 420 430 440 pF1KE3 GSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERAST 350 360 370 380 390 400 450 460 470 480 490 500 pF1KE3 KMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVV 410 420 430 440 450 460 510 520 530 540 550 560 pF1KE3 ISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQAS 470 480 490 500 510 520 570 580 590 600 610 620 pF1KE3 SSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAI 530 540 550 560 570 580 630 640 650 660 670 680 pF1KE3 RQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKV 590 600 610 620 630 640 690 700 710 720 730 740 pF1KE3 SKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISR 650 660 670 680 690 700 750 760 770 780 790 800 pF1KE3 LLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMW 710 720 730 740 750 760 810 820 830 840 850 860 pF1KE3 YGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDD 770 780 790 800 810 820 870 880 890 900 910 920 pF1KE3 TFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEA 830 840 850 860 870 880 930 940 950 960 970 980 pF1KE3 WVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQ 890 900 910 920 930 940 990 1000 1010 1020 1030 1040 pF1KE3 MDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLE 950 960 970 980 990 1000 1050 1060 1070 1080 1090 1100 pF1KE3 MVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGD 1010 1020 1030 1040 1050 1060 1110 1120 1130 1140 1150 1160 pF1KE3 EESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLC 1070 1080 1090 1100 1110 1120 1170 1180 1190 1200 1210 pF1KE3 EYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA 1130 1140 1150 1160 1170 >>NP_003639 (OMIM: 601826) diacylglycerol kinase delta i (1170 aa) initn: 7807 init1: 7807 opt: 7807 Z-score: 4677.2 bits: 877.4 E(85289): 0 Smith-Waterman score: 7807; 99.9% identity (100.0% similar) in 1163 aa overlap (52-1214:8-1170) 30 40 50 60 70 80 pF1KE3 EESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRT .::::::::::::::::::::::::::::: NP_003 MNMFLYFQTIIKEGMLTKQNNSFQRSKRRYFKLRGRT 10 20 30 90 100 110 120 130 140 pF1KE3 LYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAAL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE3 KTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKA 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE3 HKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLR 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE3 LQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSP 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE3 LLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDG 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE3 SVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTK 340 350 360 370 380 390 450 460 470 480 490 500 pF1KE3 MLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVI 400 410 420 430 440 450 510 520 530 540 550 560 pF1KE3 SSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASS 460 470 480 490 500 510 570 580 590 600 610 620 pF1KE3 SLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIR 520 530 540 550 560 570 630 640 650 660 670 680 pF1KE3 QIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVS 580 590 600 610 620 630 690 700 710 720 730 740 pF1KE3 KSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRL 640 650 660 670 680 690 750 760 770 780 790 800 pF1KE3 LINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWY 700 710 720 730 740 750 810 820 830 840 850 860 pF1KE3 GVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDT 760 770 780 790 800 810 870 880 890 900 910 920 pF1KE3 FAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAW 820 830 840 850 860 870 930 940 950 960 970 980 pF1KE3 VQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQM 880 890 900 910 920 930 990 1000 1010 1020 1030 1040 pF1KE3 DQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEM 940 950 960 970 980 990 1050 1060 1070 1080 1090 1100 pF1KE3 VNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDE 1000 1010 1020 1030 1040 1050 1110 1120 1130 1140 1150 1160 pF1KE3 ESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCE 1060 1070 1080 1090 1100 1110 1170 1180 1190 1200 1210 pF1KE3 YKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA 1120 1130 1140 1150 1160 1170 >>XP_011510330 (OMIM: 601826) PREDICTED: diacylglycerol (1238 aa) initn: 7806 init1: 7806 opt: 7806 Z-score: 4676.2 bits: 877.4 E(85289): 0 Smith-Waterman score: 7806; 99.5% identity (99.6% similar) in 1170 aa overlap (45-1214:69-1238) 20 30 40 50 60 70 pF1KE3 PPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRY :: . :::::::::::::::::::::: XP_011 VPLLPGNPGLAGVTSSTTWTGAEGQRMDLRTSWPRTRTTIIKEGMLTKQNNSFQRSKRRY 40 50 60 70 80 90 80 90 100 110 120 130 pF1KE3 FKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEM 100 110 120 130 140 150 140 150 160 170 180 190 pF1KE3 EDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSC 160 170 180 190 200 210 200 210 220 230 240 250 pF1KE3 EVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDK 220 230 240 250 260 270 260 270 280 290 300 310 pF1KE3 TCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASC 280 290 300 310 320 330 320 330 340 350 360 370 pF1KE3 PPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRI 340 350 360 370 380 390 380 390 400 410 420 430 pF1KE3 LVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEK 400 410 420 430 440 450 440 450 460 470 480 490 pF1KE3 LERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTS 460 470 480 490 500 510 500 510 520 530 540 550 pF1KE3 DQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLD 520 530 540 550 560 570 560 570 580 590 600 610 pF1KE3 DESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRAN 580 590 600 610 620 630 620 630 640 650 660 670 pF1KE3 SLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKG 640 650 660 670 680 690 680 690 700 710 720 730 pF1KE3 RSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPG 700 710 720 730 740 750 740 750 760 770 780 790 pF1KE3 GSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSR 760 770 780 790 800 810 800 810 820 830 840 850 pF1KE3 TKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWG 820 830 840 850 860 870 860 870 880 890 900 910 pF1KE3 GTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPV 880 890 900 910 920 930 920 930 940 950 960 970 pF1KE3 QVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLS 940 950 960 970 980 990 980 990 1000 1010 1020 1030 pF1KE3 EEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLN 1000 1010 1020 1030 1040 1050 1040 1050 1060 1070 1080 1090 pF1KE3 CSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQ 1060 1070 1080 1090 1100 1110 1100 1110 1120 1130 1140 1150 pF1KE3 SAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWL 1120 1130 1140 1150 1160 1170 1160 1170 1180 1190 1200 1210 pF1KE3 EHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA 1180 1190 1200 1210 1220 1230 >>XP_011510333 (OMIM: 601826) PREDICTED: diacylglycerol (1156 aa) initn: 7770 init1: 7770 opt: 7770 Z-score: 4655.1 bits: 873.4 E(85289): 0 Smith-Waterman score: 7770; 100.0% identity (100.0% similar) in 1156 aa overlap (59-1214:1-1156) 30 40 50 60 70 80 pF1KE3 PEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTA :::::::::::::::::::::::::::::: XP_011 MLTKQNNSFQRSKRRYFKLRGRTLYYAKTA 10 20 30 90 100 110 120 130 140 pF1KE3 KSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNRE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE3 HFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVR 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE3 ATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE3 WCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNS 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE3 KSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLS 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE3 EIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSV 340 350 360 370 380 390 450 460 470 480 490 500 pF1KE3 MAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLC 400 410 420 430 440 450 510 520 530 540 550 560 pF1KE3 ETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPP 460 470 480 490 500 510 570 580 590 600 610 620 pF1KE3 TIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTE 520 530 540 550 560 570 630 640 650 660 670 680 pF1KE3 KAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKL 580 590 600 610 620 630 690 700 710 720 730 740 pF1KE3 ISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPF 640 650 660 670 680 690 750 760 770 780 790 800 pF1KE3 NSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKE 700 710 720 730 740 750 810 820 830 840 850 860 pF1KE3 LLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFD 760 770 780 790 800 810 870 880 890 900 910 920 pF1KE3 DKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYI 820 830 840 850 860 870 930 940 950 960 970 980 pF1KE3 RIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAA 880 890 900 910 920 930 990 1000 1010 1020 1030 1040 pF1KE3 GVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRAL 940 950 960 970 980 990 1050 1060 1070 1080 1090 1100 pF1KE3 RSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDL 1000 1010 1020 1030 1040 1050 1110 1120 1130 1140 1150 1160 pF1KE3 AKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTR 1060 1070 1080 1090 1100 1110 1170 1180 1190 1200 1210 pF1KE3 HDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA :::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA 1120 1130 1140 1150 >>XP_011510334 (OMIM: 601826) PREDICTED: diacylglycerol (1156 aa) initn: 7770 init1: 7770 opt: 7770 Z-score: 4655.1 bits: 873.4 E(85289): 0 Smith-Waterman score: 7770; 100.0% identity (100.0% similar) in 1156 aa overlap (59-1214:1-1156) 30 40 50 60 70 80 pF1KE3 PEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTA :::::::::::::::::::::::::::::: XP_011 MLTKQNNSFQRSKRRYFKLRGRTLYYAKTA 10 20 30 90 100 110 120 130 140 pF1KE3 KSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNRE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE3 HFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVR 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE3 ATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE3 WCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFVNS 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE3 KSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLS 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE3 EIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSV 340 350 360 370 380 390 450 460 470 480 490 500 pF1KE3 MAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLC 400 410 420 430 440 450 510 520 530 540 550 560 pF1KE3 ETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPP 460 470 480 490 500 510 570 580 590 600 610 620 pF1KE3 TIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTE 520 530 540 550 560 570 630 640 650 660 670 680 pF1KE3 KAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCEKL 580 590 600 610 620 630 690 700 710 720 730 740 pF1KE3 ISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINADPF 640 650 660 670 680 690 750 760 770 780 790 800 pF1KE3 NSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKE 700 710 720 730 740 750 810 820 830 840 850 860 pF1KE3 LLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFD 760 770 780 790 800 810 870 880 890 900 910 920 pF1KE3 DKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYI 820 830 840 850 860 870 930 940 950 960 970 980 pF1KE3 RIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAA 880 890 900 910 920 930 990 1000 1010 1020 1030 1040 pF1KE3 GVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRAL 940 950 960 970 980 990 1050 1060 1070 1080 1090 1100 pF1KE3 RSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVMLDL 1000 1010 1020 1030 1040 1050 1110 1120 1130 1140 1150 1160 pF1KE3 AKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTR 1060 1070 1080 1090 1100 1110 1170 1180 1190 1200 1210 pF1KE3 HDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA :::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA 1120 1130 1140 1150 >>XP_016860628 (OMIM: 601826) PREDICTED: diacylglycerol (1141 aa) initn: 7427 init1: 7427 opt: 7427 Z-score: 4450.3 bits: 835.4 E(85289): 0 Smith-Waterman score: 7427; 99.5% identity (99.9% similar) in 1105 aa overlap (110-1214:37-1141) 80 90 100 110 120 130 pF1KE3 RTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIA .:...: ::::::::::::::::::::::: XP_016 LFVWWCLFLCFVWCSVRKSVVYAHPSCFEWSVSGGFQVITPCRKLILCADNRKEMEDWIA 10 20 30 40 50 60 140 150 160 170 180 190 pF1KE3 ALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKF 70 80 90 100 110 120 200 210 220 230 240 250 pF1KE3 KAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSV 130 140 150 160 170 180 260 270 280 290 300 310 pF1KE3 LRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCT 190 200 210 220 230 240 320 330 340 350 360 370 pF1KE3 SPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGG 250 260 270 280 290 300 380 390 400 410 420 430 pF1KE3 DGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERAS 310 320 330 340 350 360 440 450 460 470 480 490 pF1KE3 TKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSV 370 380 390 400 410 420 500 510 520 530 540 550 pF1KE3 VISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQA 430 440 450 460 470 480 560 570 580 590 600 610 pF1KE3 SSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKA 490 500 510 520 530 540 620 630 640 650 660 670 pF1KE3 IRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRK 550 560 570 580 590 600 680 690 700 710 720 730 pF1KE3 VSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVIS 610 620 630 640 650 660 740 750 760 770 780 790 pF1KE3 RLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMM 670 680 690 700 710 720 800 810 820 830 840 850 pF1KE3 WYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKED 730 740 750 760 770 780 860 870 880 890 900 910 pF1KE3 DTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGE 790 800 810 820 830 840 920 930 940 950 960 970 pF1KE3 AWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEAT 850 860 870 880 890 900 980 990 1000 1010 1020 1030 pF1KE3 QMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVL 910 920 930 940 950 960 1040 1050 1060 1070 1080 1090 pF1KE3 EMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPG 970 980 990 1000 1010 1020 1100 1110 1120 1130 1140 1150 pF1KE3 DEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSL 1030 1040 1050 1060 1070 1080 1160 1170 1180 1190 1200 1210 pF1KE3 CEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA 1090 1100 1110 1120 1130 1140 >>XP_005246164 (OMIM: 601826) PREDICTED: diacylglycerol (1102 aa) initn: 7413 init1: 7413 opt: 7413 Z-score: 4442.1 bits: 833.9 E(85289): 0 Smith-Waterman score: 7413; 100.0% identity (100.0% similar) in 1098 aa overlap (117-1214:5-1102) 90 100 110 120 130 140 pF1KE3 TAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQN :::::::::::::::::::::::::::::: XP_005 MHSKVITPCRKLILCADNRKEMEDWIAALKTVQN 10 20 30 150 160 170 180 190 200 pF1KE3 REHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCA 40 50 60 70 80 90 210 220 230 240 250 260 pF1KE3 VRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWR 100 110 120 130 140 150 270 280 290 300 310 320 pF1KE3 CLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASCPPSCTSPLLVFV 160 170 180 190 200 210 330 340 350 360 370 380 pF1KE3 NSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWV 220 230 240 250 260 270 390 400 410 420 430 440 pF1KE3 LSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRW 280 290 300 310 320 330 450 460 470 480 490 500 pF1KE3 SVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKV 340 350 360 370 380 390 510 520 530 540 550 560 pF1KE3 LCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLPNP 400 410 420 430 440 450 570 580 590 600 610 620 pF1KE3 PPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEH 460 470 480 490 500 510 630 640 650 660 670 680 pF1KE3 TEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKGRSQRKVSKSPCE 520 530 540 550 560 570 690 700 710 720 730 740 pF1KE3 KLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPGGSVISRLLINAD 580 590 600 610 620 630 750 760 770 780 790 800 pF1KE3 PFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGT 640 650 660 670 680 690 810 820 830 840 850 860 pF1KE3 KELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPS 700 710 720 730 740 750 870 880 890 900 910 920 pF1KE3 FDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPG 760 770 780 790 800 810 930 940 950 960 970 980 pF1KE3 YIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQ 820 830 840 850 860 870 990 1000 1010 1020 1030 1040 pF1KE3 AAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFR 880 890 900 910 920 930 1050 1060 1070 1080 1090 1100 pF1KE3 ALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEESVML 940 950 960 970 980 990 1110 1120 1130 1140 1150 1160 pF1KE3 DLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIF 1000 1010 1020 1030 1040 1050 1170 1180 1190 1200 1210 pF1KE3 TRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA 1060 1070 1080 1090 1100 >>XP_011510331 (OMIM: 601826) PREDICTED: diacylglycerol (1211 aa) initn: 7315 init1: 7315 opt: 7315 Z-score: 4383.0 bits: 823.1 E(85289): 0 Smith-Waterman score: 7315; 99.5% identity (99.5% similar) in 1097 aa overlap (45-1141:69-1165) 20 30 40 50 60 70 pF1KE3 PPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRY :: . :::::::::::::::::::::: XP_011 VPLLPGNPGLAGVTSSTTWTGAEGQRMDLRTSWPRTRTTIIKEGMLTKQNNSFQRSKRRY 40 50 60 70 80 90 80 90 100 110 120 130 pF1KE3 FKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEM 100 110 120 130 140 150 140 150 160 170 180 190 pF1KE3 EDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSC 160 170 180 190 200 210 200 210 220 230 240 250 pF1KE3 EVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDK 220 230 240 250 260 270 260 270 280 290 300 310 pF1KE3 TCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTALNSIDSDGFWKASC 280 290 300 310 320 330 320 330 340 350 360 370 pF1KE3 PPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRI 340 350 360 370 380 390 380 390 400 410 420 430 pF1KE3 LVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEK 400 410 420 430 440 450 440 450 460 470 480 490 pF1KE3 LERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTS 460 470 480 490 500 510 500 510 520 530 540 550 pF1KE3 DQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCSVLKEKLDSLLKTLD 520 530 540 550 560 570 560 570 580 590 600 610 pF1KE3 DESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRAN 580 590 600 610 620 630 620 630 640 650 660 670 pF1KE3 SLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSHSESFGVPKG 640 650 660 670 680 690 680 690 700 710 720 730 pF1KE3 RSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAGMSGSLPG 700 710 720 730 740 750 740 750 760 770 780 790 pF1KE3 GSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSR 760 770 780 790 800 810 800 810 820 830 840 850 pF1KE3 TKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWG 820 830 840 850 860 870 860 870 880 890 900 910 pF1KE3 GTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPV 880 890 900 910 920 930 920 930 940 950 960 970 pF1KE3 QVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLS 940 950 960 970 980 990 980 990 1000 1010 1020 1030 pF1KE3 EEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLN 1000 1010 1020 1030 1040 1050 1040 1050 1060 1070 1080 1090 pF1KE3 CSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLADTPWLCQ 1060 1070 1080 1090 1100 1110 1100 1110 1120 1130 1140 1150 pF1KE3 SAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWL ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGAPGPGRDQGGPHEED 1120 1130 1140 1150 1160 1170 1160 1170 1180 1190 1200 1210 pF1KE3 EHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSRSAPAVEA XP_011 PVWHQGAEPQRPRRRGLASVLSACGLHIPAAEA 1180 1190 1200 1210 1214 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 19:39:37 2016 done: Sun Nov 6 19:39:39 2016 Total Scan time: 16.570 Total Display time: 0.500 Function used was FASTA [36.3.4 Apr, 2011]