Result of FASTA (ccds) for
pF1KE3451
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3451, 1321 aa
1>>>pF1KE3451 1321 - 1321 aa - 1321 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.4507+/-0.00117; mu= -20.9598+/- 0.071
mean_var=628.5641+/-130.935, 0's: 0 Z-trim(116.8): 38 B-trim: 0 in 0/54
Lambda= 0.051156
statistics sampled from 17619 (17655) to 17619 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.528), width: 16
Scan time: 3.920
The best scores are: opt bits E(33420)
CCDS34455.1 TTBK1 gene_id:84630|Hs109|chr6 (1321) 8787 664.3 6e-190
CCDS42029.1 TTBK2 gene_id:146057|Hs109|chr15 (1244) 2118 172.1 8.3e-42
>>CCDS34455.1 TTBK1 gene_id:84630|Hs109|chr6 (1321 aa)
initn: 8787 init1: 8787 opt: 8787 Z-score: 3523.9 bits: 664.3 E(33420): 6e-190
Smith-Waterman score: 8787; 100.0% identity (100.0% similar) in 1321 aa overlap (1-1321:1-1321)
10 20 30 40 50 60
pF1KE3 MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 QPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 RQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 RQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 KIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 GEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 EEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 EEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 KEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 KEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 QALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 RQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 RQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 PGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 GAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGEL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 GLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPAL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ADGPAPVSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ADGPAPVSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 KRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 KRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 ALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 ATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 SPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGA
1270 1280 1290 1300 1310 1320
pF1KE3 R
:
CCDS34 R
>>CCDS42029.1 TTBK2 gene_id:146057|Hs109|chr15 (1244 aa)
initn: 2389 init1: 1808 opt: 2118 Z-score: 864.2 bits: 172.1 E(33420): 8.3e-42
Smith-Waterman score: 2384; 39.2% identity (59.9% similar) in 1361 aa overlap (14-1314:1-1219)
10 20 30 40 50 60
pF1KE3 MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENV
::::::: ::: .. .::.:::::.:::::::::::.:.:.::::::
CCDS42 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENV
10 20 30 40
70 80 90 100 110 120
pF1KE3 ALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRS
:::::::::::::::::::::::::::::::::::::::..:::::::::::::::::::
CCDS42 ALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 QPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLA
: :::::.:::::::.:::::::.::::::::::::::::::::.::: :::::::::::
CCDS42 QSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 RQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWR
::.::. ::::::: ::::::::::::.:::.::::::::::::::::::::.:::::::
CCDS42 RQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 KIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKER
::::::::: :::.:.::..:::.: :: .:::::.::::::::::::. :::.::.:
CCDS42 KIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTF
230 240 250 260 270 280
310 320 330 340 350
pF1KE3 GIAENEAFDWEKAGTD-ALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVL
:. :.. :::::.:.: .: .:.::: :: .:: : : .:..:.::.:::::::::..:.
CCDS42 GVIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVF
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE3 QGEHLSDQENAPPILPGRPSEGLGPS--PHLVPHPGGPEAEVWEETDVNRNKLRINIGKS
:.::: ::. :. :..:. : . :: : .:::: :.:.::....: :.
CCDS42 PDEQLSDGENGIPV-------GVSPDKLPGSLGHPRPQEKDVWEEMDANKNKIKLGICKA
350 360 370 380 390 400
420 430 440 450 460
pF1KE3 PCVEEEQSRG-----MGVPS--SPVRA-----PPDSPTTPVRSLRYRRVNSPESE-RLST
.:::.:.: ...:: ::.:. :: ::.: : ..: : : ::.
CCDS42 A-TEEENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKL--RSIHSFELEKRLTL
410 420 430 440 450
470 480 490 500 510
pF1KE3 -----ADGRVELPERRSRMDLPGS-----PSRQACSSQPAQMLSVDTGHADRQ--ASGRM
.: .: .. . : .. :. :: . : :.. ..
CCDS42 EPKPDTDKFLETCLEKMQKDTSAGKESILPALLHKPCVPAVSRTDHIWHYDEEYLPDASK
460 470 480 490 500 510
520 530 540 550 560
pF1KE3 DVSASVEQEAL---SNAFRSVPLAE-EEDFDSKEWVIIDKETELKDFPPG---AEPSTSG
.::.. ..: ::.: .: :. ....:::::::.::: .:.:: . .. .:..
CCDS42 PASANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGS
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE3 TTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPPQLS-QGD
.::::: :. : : . . ..: : ::.: :: . :. ...
CCDS42 PSDEEPEVLQVL-EASPQDEKLQLGP-----------WAEND--HLKKETSGVVLALSAE
580 590 600 610 620
630 640 650 660 670 680
pF1KE3 GRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLSLP
: ::: .: ... : : .: : : : .: : . ::.
CCDS42 G------PPTAASEQYTD--------RLELQP-GAASQ-FIAATPTSLMEAQAEGPLTA-
630 640 650 660
690 700 710 720 730 740
pF1KE3 YQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEE
.: :. .: .: ... . .. :. . .
CCDS42 ------------------------------ITIPRPSVASTQSTSGSFHCGQQPEKKDLQ
670 680 690
750 760 770 780 790 800
pF1KE3 EEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGA
: : .:. : : ... . :: . . : . . : ...::. .
CCDS42 PMEPTVELYSPRENFSGLVVTEGEPPSGGSRTDLGLQID-HIGHDMLPNIRESNKSQDLG
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE3 PSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGD---MKKSPVTAELAPDPDLGT
:. : .. : .. : :: :...: : .. .... :.. : :
CCDS42 PKELPDHNRLVVREFENLPG---ETEE--KSILLESDNEDEKLSRGQHCIEISSLP--GD
760 770 780 790 800
870 880 890 900 910 920
pF1KE3 LAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTVTTGVGGVAVTSS
:. . .: . : :::.. :.: : :. . . : :: ..:
CCDS42 LVIVEKDH---SATTEPLDVTKTQTFSVV-------PNQDKNNEIMKLLT-VGTSEISSR
810 820 830 840 850
930 940 950 960 970 980
pF1KE3 PFT-KVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELASDGGAVEEGARAPLE
. .:: . ..:: . : .:. . . . . :.:. : ..: . . .
CCDS42 DIDPHVEGQIGQVAE-MQKNKISKDDDIMSEDLPGHQGDLSTFLHQEG----KREKITPR
860 870 880 890 900 910
990 1000 1010 1020 1030 1040
pF1KE3 NGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAPVSPLEPSPEKVATI
:: . .. : ::: : ..:. .:. :.
CCDS42 NGELFHCVSENE------HGAP--TRKDMVRSSF------------VT------------
920 930 940
1050 1060 1070 1080 1090 1100
pF1KE3 SPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGR
:: :::::: .: :. : :. .::::. .. : ::..:..:::: .
CCDS42 ---RH--------SRIPVLAQEIDSTLESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFK
950 960 970 980
1110 1120 1130 1140
pF1KE3 LLLRLASGASSSSSEEQRRASETLSGTGSEED--TPASEPA--AALPRKSGRA-------
.: :.::.. ::. :. . ::. :: :. . . : :.. .
CCDS42 SFLGDLSSASDKLLEEK---LATVPAPFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIIS
990 1000 1010 1020 1030 1040
1150 1160 1170 1180 1190 1200
pF1KE3 AATRSRIPRPIGLRMPMPV---AAQQPASRSHGAAPALDTAITSRLQLQTPPGSATA-AD
. .:.::::.. : ...: : . : .. .::. ::... .:
CCDS42 QSRKSKIPRPVSWVNTDQVNSSTSSQFFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSD
1050 1060 1070 1080 1090 1100
1210 1220 1230 1240 1250 1260
pF1KE3 L--RPKQPPGRGLGPGRAQAGARPP-APRSPRLPASTSAA--RNASASPRSQSLSRRESP
: : : : :. . . : .:..:. : .. .. :. ::::::.:: : :
CCDS42 LFSRLAQILQNGSQKPRSTTQCKSPGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSS
1110 1120 1130 1140 1150 1160
1270 1280 1290 1300 1310 1320
pF1KE3 SPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGA
:::. .:: :. : .. . :: .::... :. : . .:. :.
CCDS42 SPSRAGRPH-HDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCKPSKNGLKGSGSLHHH
1170 1180 1190 1200 1210 1220
pF1KE3 R
CCDS42 SASTKTPQGKSKPASKLSR
1230 1240
1321 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 15:55:22 2019 done: Tue Jul 16 15:55:23 2019
Total Scan time: 3.920 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]