Result of FASTA (omim) for
pF1KE3466
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3466, 1390 aa
1>>>pF1KE3466 1390 - 1390 aa - 1390 aa
Library: /omim/omim.rfq.tfa
64236559 residues in 92054 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.4867+/-0.00099; mu= -11.3727+/- 0.057
mean_var=920.5072+/-219.500, 0's: 0 Z-trim(110.8): 1160 B-trim: 1212 in 1/48
Lambda= 0.042273
statistics sampled from 18674 (19995) to 18674 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.536), E-opt: 0.2 (0.217), width: 16
Scan time: 7.390
The best scores are: opt bits E(92054)
NP_000236 (OMIM: 114550,164860,605074,607278,61670 (1390) 9334 588.3 1.4e-166
XP_011514525 (OMIM: 114550,164860,605074,607278,61 (1409) 9334 588.4 1.4e-166
NP_001311331 (OMIM: 114550,164860,605074,607278,61 ( 960) 6415 410.1 4.4e-113
XP_006716053 (OMIM: 114550,164860,605074,607278,61 ( 960) 6415 410.1 4.4e-113
NP_001311330 (OMIM: 114550,164860,605074,607278,61 ( 934) 6126 392.4 8.8e-108
NP_001120972 (OMIM: 114550,164860,605074,607278,61 (1408) 5103 330.3 6.6e-89
XP_005265227 (OMIM: 600168,617075) macrophage-stim (1401) 2164 151.1 5.9e-35
NP_002438 (OMIM: 600168,617075) macrophage-stimula (1400) 2161 150.9 6.7e-35
XP_011532044 (OMIM: 600168,617075) macrophage-stim (1324) 1754 126.0 1.9e-27
XP_011532045 (OMIM: 600168,617075) macrophage-stim (1300) 1472 108.8 2.9e-22
XP_011532046 (OMIM: 600168,617075) macrophage-stim (1295) 1467 108.5 3.6e-22
NP_001305842 (OMIM: 600168,617075) macrophage-stim (1294) 1464 108.3 4e-22
NP_001231866 (OMIM: 600168,617075) macrophage-stim (1351) 1318 99.5 2e-19
XP_011532042 (OMIM: 600168,617075) macrophage-stim (1352) 1318 99.5 2e-19
XP_011532041 (OMIM: 600168,617075) macrophage-stim (1361) 1318 99.5 2e-19
XP_011532043 (OMIM: 600168,617075) macrophage-stim (1332) 1253 95.5 3.1e-18
NP_006334 (OMIM: 604705,613862) tyrosine-protein k ( 999) 847 70.5 7.5e-11
NP_001265528 (OMIM: 109135,146110) tyrosine-protei ( 626) 793 66.9 5.7e-10
NP_001690 (OMIM: 109135,146110) tyrosine-protein k ( 885) 793 67.2 6.9e-10
NP_068713 (OMIM: 109135,146110) tyrosine-protein k ( 894) 793 67.2 6.9e-10
NP_001005861 (OMIM: 600524) tyrosine-protein kinas ( 610) 733 63.2 7.2e-09
NP_002949 (OMIM: 600524) tyrosine-protein kinase R ( 607) 724 62.7 1e-08
XP_011519819 (OMIM: 147370,270450) insulin-like gr ( 922) 716 62.5 1.8e-08
NP_001317193 (OMIM: 600341) tyrosine-protein kinas ( 845) 714 62.3 1.9e-08
NP_006284 (OMIM: 600341) tyrosine-protein kinase r ( 890) 714 62.3 2e-08
XP_024305681 (OMIM: 147370,270450) insulin-like gr (1064) 716 62.6 2e-08
XP_011519818 (OMIM: 147370,270450) insulin-like gr (1064) 716 62.6 2e-08
XP_016877628 (OMIM: 147370,270450) insulin-like gr (1246) 716 62.7 2.1e-08
NP_001278787 (OMIM: 147370,270450) insulin-like gr (1366) 716 62.8 2.2e-08
NP_000866 (OMIM: 147370,270450) insulin-like growt (1367) 716 62.8 2.2e-08
XP_016877627 (OMIM: 147370,270450) insulin-like gr (1391) 716 62.8 2.3e-08
XP_016877625 (OMIM: 147370,270450) insulin-like gr (1392) 716 62.8 2.3e-08
XP_016877626 (OMIM: 147370,270450) insulin-like gr (1392) 716 62.8 2.3e-08
XP_011526291 (OMIM: 147670,246200,262190,609968,61 (1369) 706 62.1 3.4e-08
NP_001073285 (OMIM: 147670,246200,262190,609968,61 (1370) 706 62.1 3.4e-08
XP_011526290 (OMIM: 147670,246200,262190,609968,61 (1381) 706 62.2 3.4e-08
NP_000199 (OMIM: 147670,246200,262190,609968,61054 (1382) 706 62.2 3.5e-08
NP_001129473 (OMIM: 164690) tyrosine-protein kinas ( 542) 682 60.1 5.8e-08
NP_055030 (OMIM: 147671) insulin receptor-related (1297) 690 61.1 6.6e-08
NP_001161711 (OMIM: 164690) tyrosine-protein kinas (1043) 687 60.8 6.6e-08
NP_001161710 (OMIM: 164690) tyrosine-protein kinas (1058) 687 60.8 6.7e-08
NP_001129472 (OMIM: 164690) tyrosine-protein kinas (1064) 687 60.8 6.7e-08
NP_001161709 (OMIM: 164690) tyrosine-protein kinas (1079) 687 60.8 6.8e-08
XP_005245145 (OMIM: 164690) tyrosine-protein kinas (1146) 687 60.9 7e-08
NP_001161708 (OMIM: 164690) tyrosine-protein kinas (1161) 687 60.9 7e-08
NP_005149 (OMIM: 164690) tyrosine-protein kinase A (1167) 687 60.9 7e-08
NP_009298 (OMIM: 164690) tyrosine-protein kinase A (1182) 687 60.9 7.1e-08
XP_016856524 (OMIM: 164690) tyrosine-protein kinas (1182) 687 60.9 7.1e-08
NP_001294960 (OMIM: 176942) tyrosine-protein kinas ( 453) 674 59.4 7.4e-08
XP_016859071 (OMIM: 600543,615515) receptor tyrosi (1116) 685 60.7 7.5e-08
>>NP_000236 (OMIM: 114550,164860,605074,607278,616705) h (1390 aa)
initn: 9334 init1: 9334 opt: 9334 Z-score: 3112.3 bits: 588.3 E(92054): 1.4e-166
Smith-Waterman score: 9334; 100.0% identity (100.0% similar) in 1390 aa overlap (1-1390:1-1390)
10 20 30 40 50 60
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 CRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 HPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVD
1330 1340 1350 1360 1370 1380
1390
pF1KE3 TRPASFWETS
::::::::::
NP_000 TRPASFWETS
1390
>>XP_011514525 (OMIM: 114550,164860,605074,607278,616705 (1409 aa)
initn: 9334 init1: 9334 opt: 9334 Z-score: 3112.3 bits: 588.4 E(92054): 1.4e-166
Smith-Waterman score: 9334; 100.0% identity (100.0% similar) in 1390 aa overlap (1-1390:20-1409)
10 20 30 40
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKY
:::::::::::::::::::::::::::::::::::::::::
XP_011 MKSKSKSLAECFPYDKPLIMKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 QLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 SSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 FSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 TKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRF
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 CSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDI
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 LFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRT
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 LLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGR
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 FMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCR
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 HFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRL
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIIS
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 NGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 VSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTIT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 GVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFF
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 MLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKS
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 CENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSI
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 STALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESV
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 DYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPE
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 LVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEV
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 SQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDL
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE3 IGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKT
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KE3 GAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRR
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KE3 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKC
1330 1340 1350 1360 1370 1380
1370 1380 1390
pF1KE3 VAPYPSLLSSEDNADDEVDTRPASFWETS
:::::::::::::::::::::::::::::
XP_011 VAPYPSLLSSEDNADDEVDTRPASFWETS
1390 1400
>>NP_001311331 (OMIM: 114550,164860,605074,607278,616705 (960 aa)
initn: 6415 init1: 6415 opt: 6415 Z-score: 2151.8 bits: 410.1 E(92054): 4.4e-113
Smith-Waterman score: 6415; 100.0% identity (100.0% similar) in 960 aa overlap (431-1390:1-960)
410 420 430 440 450 460
pF1KE3 TLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEG
::::::::::::::::::::::::::::::
NP_001 MGQFSEVLLTSISTFIKGDLTIANLGTSEG
10 20 30
470 480 490 500 510 520
pF1KE3 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
40 50 60 70 80 90
530 540 550 560 570 580
pF1KE3 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
100 110 120 130 140 150
590 600 610 620 630 640
pF1KE3 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
160 170 180 190 200 210
650 660 670 680 690 700
pF1KE3 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
220 230 240 250 260 270
710 720 730 740 750 760
pF1KE3 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTI
280 290 300 310 320 330
770 780 790 800 810 820
pF1KE3 TGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAF
340 350 360 370 380 390
830 840 850 860 870 880
pF1KE3 FMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNK
400 410 420 430 440 450
890 900 910 920 930 940
pF1KE3 SCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVS
460 470 480 490 500 510
950 960 970 980 990 1000
pF1KE3 ISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNES
520 530 540 550 560 570
1010 1020 1030 1040 1050 1060
pF1KE3 VDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNP
580 590 600 610 620 630
1070 1080 1090 1100 1110 1120
pF1KE3 ELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGE
640 650 660 670 680 690
1130 1140 1150 1160 1170 1180
pF1KE3 VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKD
700 710 720 730 740 750
1190 1200 1210 1220 1230 1240
pF1KE3 LIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNK
760 770 780 790 800 810
1250 1260 1270 1280 1290 1300
pF1KE3 TGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR
820 830 840 850 860 870
1310 1320 1330 1340 1350 1360
pF1KE3 RLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVK
880 890 900 910 920 930
1370 1380 1390
pF1KE3 CVAPYPSLLSSEDNADDEVDTRPASFWETS
::::::::::::::::::::::::::::::
NP_001 CVAPYPSLLSSEDNADDEVDTRPASFWETS
940 950 960
>>XP_006716053 (OMIM: 114550,164860,605074,607278,616705 (960 aa)
initn: 6415 init1: 6415 opt: 6415 Z-score: 2151.8 bits: 410.1 E(92054): 4.4e-113
Smith-Waterman score: 6415; 100.0% identity (100.0% similar) in 960 aa overlap (431-1390:1-960)
410 420 430 440 450 460
pF1KE3 TLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEG
::::::::::::::::::::::::::::::
XP_006 MGQFSEVLLTSISTFIKGDLTIANLGTSEG
10 20 30
470 480 490 500 510 520
pF1KE3 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGC
40 50 60 70 80 90
530 540 550 560 570 580
pF1KE3 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTR
100 110 120 130 140 150
590 600 610 620 630 640
pF1KE3 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIII
160 170 180 190 200 210
650 660 670 680 690 700
pF1KE3 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLK
220 230 240 250 260 270
710 720 730 740 750 760
pF1KE3 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTI
280 290 300 310 320 330
770 780 790 800 810 820
pF1KE3 TGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAF
340 350 360 370 380 390
830 840 850 860 870 880
pF1KE3 FMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNK
400 410 420 430 440 450
890 900 910 920 930 940
pF1KE3 SCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVS
460 470 480 490 500 510
950 960 970 980 990 1000
pF1KE3 ISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNES
520 530 540 550 560 570
1010 1020 1030 1040 1050 1060
pF1KE3 VDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNP
580 590 600 610 620 630
1070 1080 1090 1100 1110 1120
pF1KE3 ELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGE
640 650 660 670 680 690
1130 1140 1150 1160 1170 1180
pF1KE3 VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKD
700 710 720 730 740 750
1190 1200 1210 1220 1230 1240
pF1KE3 LIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNK
760 770 780 790 800 810
1250 1260 1270 1280 1290 1300
pF1KE3 TGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR
820 830 840 850 860 870
1310 1320 1330 1340 1350 1360
pF1KE3 RLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVK
880 890 900 910 920 930
1370 1380 1390
pF1KE3 CVAPYPSLLSSEDNADDEVDTRPASFWETS
::::::::::::::::::::::::::::::
XP_006 CVAPYPSLLSSEDNADDEVDTRPASFWETS
940 950 960
>>NP_001311330 (OMIM: 114550,164860,605074,607278,616705 (934 aa)
initn: 6126 init1: 6126 opt: 6126 Z-score: 2056.6 bits: 392.4 E(92054): 8.8e-108
Smith-Waterman score: 6126; 100.0% identity (100.0% similar) in 910 aa overlap (1-910:1-910)
10 20 30 40 50 60
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ
::::::::::
NP_001 LKLNSELNIEVGFLHSSHDVNKEASVIMLFSGLK
910 920 930
>>NP_001120972 (OMIM: 114550,164860,605074,607278,616705 (1408 aa)
initn: 5103 init1: 5103 opt: 5103 Z-score: 1717.8 bits: 330.3 E(92054): 6.6e-89
Smith-Waterman score: 9288; 98.7% identity (98.7% similar) in 1408 aa overlap (1-1390:1-1408)
10 20 30 40 50 60
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
670 680 690 700 710 720
730 740 750 760
pF1KE3 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFIS------------------GGSTITG
::::::::::::::::::::::::::::::::::: :::::::
NP_001 AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITG
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE3 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KE3 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KE3 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV
1330 1340 1350 1360 1370 1380
1370 1380 1390
pF1KE3 APYPSLLSSEDNADDEVDTRPASFWETS
::::::::::::::::::::::::::::
NP_001 APYPSLLSSEDNADDEVDTRPASFWETS
1390 1400
>>XP_005265227 (OMIM: 600168,617075) macrophage-stimulat (1401 aa)
initn: 2228 init1: 1269 opt: 2164 Z-score: 749.1 bits: 151.1 E(92054): 5.9e-35
Smith-Waterman score: 2597; 34.9% identity (61.9% similar) in 1411 aa overlap (7-1359:7-1364)
10 20 30 40 50
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
: ..:.::. .. . :: : .. . . ..:: .:.:.: .: ..
XP_005 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
.: .:.. : ..::. ::..: :::. . : : : :. . :
XP_005 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
:. . .::.: :.:::: .: : : . . :: . :.:: . ..:..:
XP_005 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
::::.: ::..: . . :.:....... . .:.:.:::: .:: :..
XP_005 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
180 190 200 210 220 230
240 250 260 270 280
pF1KE3 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
..:::. :: :.:::.:... :.:::::: .. : ...:::. :. . . :
XP_005 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
.: :. :.: .. ::..:.. . . . .:..:. . ::::: ... . ....:::::
XP_005 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
300 310 320 330 340 350
350 360 370 380 390
pF1KE3 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
. .: . :..::::: :... ..... :: :. : .:.
XP_005 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSF
360 370 380 390 400
400 410 420 430 440 450
pF1KE3 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
: : :. : . : .. .....::::: : .. : .:.. . ..:.:.
XP_005 --CPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE3 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
.:: .::..:: . :: .: :: : :: .::. .: . . : .: ..
XP_005 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVS-----RLGDHLLFASGDQVF
470 480 490 500 510
520 530 540 550 560 570
pF1KE3 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
..:..: ::::: .:..:: : :. :::: . : ...:: :.: :. : : . . :.
XP_005 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
520 530 540 550 560 570
580 590 600 610 620
pF1KE3 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
:.::.:.::::.:: .: .. .. .: .:. : ..:. ..
XP_005 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
580 590 600 610 620 630
630 640 650 660 670
pF1KE3 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
..: . : .. :.:. ..: :. ::. ::...::. ...: .:: :
XP_005 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
640 650 660 670 680 690
680 690 700 710 720 730
pF1KE3 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
::: ::: :. :. :.:: . ..: : : ::.. : : :: . . ..:.. :.
XP_005 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
700 710 720 730 740 750
740 750 760 770 780
pF1KE3 RETS-IFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVA
: :.:::::.: : :. ..:. : :: :..:.:. ..:.. :.. :
XP_005 VPGSWTFQYREDPVVLSISPNCGYIN--SHITICGQHLTSAW--HLVLSFHDGLRAVESR
760 770 780 790 800 810
790 800 810 820 830 840
pF1KE3 CQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVM
.:. : : : . : . . :: . . . : : . :
XP_005 QCERQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVP
820 830 840 850 860 870
850 860 870 880 890 900
pF1KE3 ISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELN
.. .. . .: : . : : . ::..::.. ..... :.: .: .: ..
XP_005 LKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQDGAP
880 890 900 910 920 930
910 920 930 940 950 960
pF1KE3 IEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKD
.. .::.:. :.... :.. .. . .:: : : : . :::.
XP_005 LQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQL--
940 950 960 970 980
970 980 990 1000 1010 1020
pF1KE3 LGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNGSCR
: :.:. :.: ... .: . . . :::. . .: . :
XP_005 -----------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLA---LPAIDGLDSTT
990 1000 1010 1020 1030
1030 1040 1050 1060 1070 1080
pF1KE3 QVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNE
:. . ....... :::.. :.: :. :. :. :.: ...: ..
XP_005 CVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTHSDR
1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 VIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
:::.:::: :::: .:. ..:.::.:::.:::.. .: :: ::..:. ..:::::.:
XP_005 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLAL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVH
.:: : :: : :.:::: :::: .:::. .::::::::.::::::.::.::: .::::
XP_005 IGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT
::::::::::::.:::::::::::::. :.:::::... :.::::::::::::: .:::
XP_005 RDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP
::::::::::::::.::::::: .. ::.: .: ::::: ::::::: ::.:: .::.
XP_005 KSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 KAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTR
.::.: ::... : :...:.:::.. :::.:.
XP_005 DPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTSHEMNVRPEQPQFSPMPGN
1330 1340 1350 1360 1370 1380
1390
pF1KE3 PASFWETS
XP_005 VRRPRPLSEPPRPT
1390 1400
>>NP_002438 (OMIM: 600168,617075) macrophage-stimulating (1400 aa)
initn: 2293 init1: 1269 opt: 2161 Z-score: 748.1 bits: 150.9 E(92054): 6.7e-35
Smith-Waterman score: 2606; 34.9% identity (61.9% similar) in 1411 aa overlap (7-1359:7-1363)
10 20 30 40 50
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
: ..:.::. .. . :: : .. . . ..:: .:.:.: .: ..
NP_002 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
.: .:.. : ..::. ::..: :::. . : : : :. . :
NP_002 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
:. . .::.: :.:::: .: : : . . :: . :.:: . ..:..:
NP_002 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
::::.: ::..: . . :.:....... . .:.:.:::: .:: :..
NP_002 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
180 190 200 210 220 230
240 250 260 270 280
pF1KE3 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
..:::. :: :.:::.:... :.:::::: .. : ...:::. :. . . :
NP_002 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
.: :. :.: .. ::..:.. . . . .:..:. . ::::: ... . ....:::::
NP_002 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
300 310 320 330 340 350
350 360 370 380 390
pF1KE3 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
. .: . :..::::: :... ..... :: :. : .:.
NP_002 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSF
360 370 380 390 400
400 410 420 430 440 450
pF1KE3 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
: : :. : . : .. .....::::: : .. : .:.. . ..:.:.
NP_002 --CPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE3 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
.:: .::..:: . :: .: :: : :: .::. .: . . : .: ..
NP_002 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVS-----RLGDHLLFASGDQVF
470 480 490 500 510
520 530 540 550 560 570
pF1KE3 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
..:..: ::::: .:..:: : :. :::: . : ...:: :.: :. : : . . :.
NP_002 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
520 530 540 550 560 570
580 590 600 610 620
pF1KE3 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
:.::.:.::::.:: .: .. .. .: .:. : ..:. ..
NP_002 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
580 590 600 610 620 630
630 640 650 660 670
pF1KE3 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
..: . : .. :.:. ..: :. ::. ::...::. ...: .:: :
NP_002 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
640 650 660 670 680 690
680 690 700 710 720 730
pF1KE3 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
::: ::: :. :. :.:: . ..: : : ::.. : : :: . . ..:.. :.
NP_002 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
700 710 720 730 740 750
740 750 760 770 780
pF1KE3 RETS-IFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVA
: :.:::::.: : :. ..:. : :: :..:.:. ..:.. :.. :
NP_002 VPGSWTFQYREDPVVLSISPNCGYIN--SHITICGQHLTSAW--HLVLSFHDGLRAVESR
760 770 780 790 800 810
790 800 810 820 830 840
pF1KE3 CQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVM
:. :. : : : . : . . :: . . . : : . :
NP_002 CE-RQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVP
820 830 840 850 860 870
850 860 870 880 890 900
pF1KE3 ISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELN
.. .. . .: : . : : . ::..::.. ..... :.: .: .: ..
NP_002 LKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQDGAP
880 890 900 910 920 930
910 920 930 940 950 960
pF1KE3 IEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKD
.. .::.:. :.... :.. .. . .:: : : : . :::.
NP_002 LQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQL--
940 950 960 970 980
970 980 990 1000 1010 1020
pF1KE3 LGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNGSCR
: :.:. :.: ... .: . . . :::. . .: . :
NP_002 -----------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLA---LPAIDGLDSTT
990 1000 1010 1020 1030
1030 1040 1050 1060 1070 1080
pF1KE3 QVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNE
:. . ....... :::.. :.: :. :. :. :.: ...: ..
NP_002 CVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTHSDR
1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 VIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
:::.:::: :::: .:. ..:.::.:::.:::.. .: :: ::..:. ..:::::.:
NP_002 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLAL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVH
.:: : :: : :.:::: :::: .:::. .::::::::.::::::.::.::: .::::
NP_002 IGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT
::::::::::::.:::::::::::::. :.:::::... :.::::::::::::: .:::
NP_002 RDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP
::::::::::::::.::::::: .. ::.: .: ::::: ::::::: ::.:: .::.
NP_002 KSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 KAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTR
.::.: ::... : :...:.:::.. :::.:.
NP_002 DPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPSTSHEMNVRPEQPQFSPMPGN
1330 1340 1350 1360 1370 1380
1390
pF1KE3 PASFWETS
NP_002 VRRPRPLSEPPRPT
1390 1400
>>XP_011532044 (OMIM: 600168,617075) macrophage-stimulat (1324 aa)
initn: 1832 init1: 873 opt: 1754 Z-score: 614.2 bits: 126.0 E(92054): 1.9e-27
Smith-Waterman score: 2187; 33.2% identity (60.5% similar) in 1318 aa overlap (7-1266:7-1271)
10 20 30 40 50
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
: ..:.::. .. . :: : .. . . ..:: .:.:.: .: ..
XP_011 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
.: .:.. : ..::. ::..: :::. . : : : :. . :
XP_011 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
:. . .::.: :.:::: .: : : . . :: . :.:: . ..:..:
XP_011 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
::::.: ::..: . . :.:....... . .:.:.:::: .:: :..
XP_011 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
180 190 200 210 220 230
240 250 260 270 280
pF1KE3 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
..:::. :: :.:::.:... :.:::::: .. : ...:::. :. . . :
XP_011 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
.: :. :.: .. ::..:.. . . . .:..:. . ::::: ... . ....:::::
XP_011 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
300 310 320 330 340 350
350 360 370 380 390
pF1KE3 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
. .: . :..::::: :... ..... :: :. : .:.
XP_011 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSF
360 370 380 390 400
400 410 420 430 440 450
pF1KE3 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
: : :. : . : .. .....::::: : .. : .:.. . ..:.:.
XP_011 --CPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE3 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
.:: .::..:: . :: .: :: : :: .::. .: . . : .: ..
XP_011 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVS-----RLGDHLLFASGDQVF
470 480 490 500 510
520 530 540 550 560 570
pF1KE3 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
..:..: ::::: .:..:: : :. :::: . : ...:: :.: :. : : . . :.
XP_011 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
520 530 540 550 560 570
580 590 600 610 620
pF1KE3 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
:.::.:.::::.:: .: .. .. .: .:. : ..:. ..
XP_011 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
580 590 600 610 620 630
630 640 650 660 670
pF1KE3 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
..: . : .. :.:. ..: :. ::. ::...::. ...: .:: :
XP_011 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
640 650 660 670 680 690
680 690 700 710 720 730
pF1KE3 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
::: ::: :. :. :.:: . ..: : : ::.. : : :: . . ..:.. :.
XP_011 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
700 710 720 730 740 750
740 750 760 770 780
pF1KE3 RETS-IFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVA
: :.:::::.: : :. ..:. : :: :..:.:. ..:.. :.. :
XP_011 VPGSWTFQYREDPVVLSISPNCGYIN--SHITICGQHLTSAW--HLVLSFHDGLRAVESR
760 770 780 790 800 810
790 800 810 820 830 840
pF1KE3 CQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVM
.:. : : : . : . . :: . . . : : . :
XP_011 QCERQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVP
820 830 840 850 860 870
850 860 870 880 890 900
pF1KE3 ISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELN
.. .. . .: : . : : . ::..::.. ..... :.: .: .: ..
XP_011 LKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQDGAP
880 890 900 910 920 930
910 920 930 940 950 960
pF1KE3 IEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKD
.. .::.:. :.... :.. .. . .:: : : : . :::.
XP_011 LQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQL--
940 950 960 970 980
970 980 990 1000 1010 1020
pF1KE3 LGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNGSCR
: :.:. :.: ... .: . . . :::. . .: . :
XP_011 -----------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLA---LPAIDGLDSTT
990 1000 1010 1020 1030
1030 1040 1050 1060 1070 1080
pF1KE3 QVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNE
:. . ....... :::.. :.: :. :. :. :.: ...: ..
XP_011 CVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTHSDR
1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 VIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
:::.:::: :::: .:. ..:.::.:::.:::.. .: :: ::..:. ..:::::.:
XP_011 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLAL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVH
.:: : :: : :.:::: :::: .:::. .::::::::.::::::.::.::: .::::
XP_011 IGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT
::::::::::::.:::::::::::::. :.:::::... :.::::::::::::: .:::
XP_011 RDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP
::::
XP_011 KSDVVPSDAAMLGGRPSSATHLQSTSGGGGADSVCTAWGPLCAAASNLHELGPQHLA
1270 1280 1290 1300 1310 1320
>>XP_011532045 (OMIM: 600168,617075) macrophage-stimulat (1300 aa)
initn: 1693 init1: 591 opt: 1472 Z-score: 521.3 bits: 108.8 E(92054): 2.9e-22
Smith-Waterman score: 1905; 31.4% identity (59.3% similar) in 1263 aa overlap (7-1211:7-1216)
10 20 30 40 50
pF1KE3 MKAPAVLAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVIL
: ..:.::. .. . :: : .. . . ..:: .:.:.: .: ..
XP_011 MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 HEHH-----IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVW
.: .:.. : ..::. ::..: :::. . : : : :. . :
XP_011 YEGDRNESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG--
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 KDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQC
:. . .::.: :.:::: .: : : . . :: . :.:: . ..:..:
XP_011 -DTDTKVLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 PDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLT
::::.: ::..: . . :.:....... . .:.:.:::: .:: :..
XP_011 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA
180 190 200 210 220 230
240 250 260 270 280
pF1KE3 DQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGL
..:::. :: :.:::.:... :.:::::: .. : ...:::. :. . . :
XP_011 ----LSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPEL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 HSYMEMPLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVF
.: :. :.: .. ::..:.. . . . .:..:. . ::::: ... . ....:::::
XP_011 GDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVF
300 310 320 330 340 350
350 360 370 380 390
pF1KE3 AQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRC------------LQHFYGPNH
. .: . :..::::: :... ..... :: :. : .:.
XP_011 VTGKDGGPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPS-
360 370 380 390 400
400 410 420 430 440 450
pF1KE3 EHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIAN
: : :. : . : .. .....::::: : .. : .:.. . ..:.:.
XP_011 -FCPNPPGLEALSPNTSCR-HFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAH
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE3 LGTSEGRFMQVVVSRSGPSTPHV-NFLL-DS-HPVSPEVIVEHTLNQNGYTLVITGKKIT
.:: .::..:: . :: .: :: : :: .::. .: :.. . : .: ..
XP_011 MGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDV---SRLGD--HLLFASGDQVF
470 480 490 500 510
520 530 540 550 560 570
pF1KE3 KIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPN
..:..: ::::: .:..:: : :. :::: . : ...:: :.: :. : : . . :.
XP_011 QVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPH
520 530 540 550 560 570
580 590 600 610 620
pF1KE3 SAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNT
:.::.:.::::.:: .: .. .. .: .:. : ..:. ..
XP_011 SGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEE
580 590 600 610 620 630
630 640 650 660 670
pF1KE3 LKCTVGPAMNKHF---NMSIIISN---GH-----GTTQYSTFSYVDPVITSISPKYGPMA
..: . : .. :.:. ..: :. ::. ::...::. ...: .:: :
XP_011 FECELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRA
640 650 660 670 680 690
680 690 700 710 720 730
pF1KE3 GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN
::: ::: :. :. :.:: . ..: : : ::.. : : :: . . ..:.. :.
XP_011 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQ
700 710 720 730 740 750
740 750 760 770 780
pF1KE3 RETS-IFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVA
: :.:::::.: : :. ..:. : :: :..:.:. ..:.. :.. :
XP_011 VPGSWTFQYREDPVVLSISPNCGYIN--SHITICGQHLTSAW--HLVLSFHDGLRAVESR
760 770 780 790 800 810
790 800 810 820 830 840
pF1KE3 CQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVM
.:. : : : . : . . :: . . . : : . :
XP_011 QCERQLPEQQLCRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVP
820 830 840 850 860 870
850 860 870 880 890 900
pF1KE3 ISMGNENV-LEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELN
.. .. . .: : . : : . ::..::.. ..... :.: .: .: ..
XP_011 LKPEEHAIKFEYIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQDGAP
880 890 900 910 920 930
910 920 930 940 950 960
pF1KE3 IEWKQAISSTVLGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKD
.. .::.:. :.... :.. .. . .:: : : : . :::.
XP_011 LQVCVDGECHILGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQL--
940 950 960 970 980
970 980 990 1000 1010 1020
pF1KE3 LGSELVRYDARVHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNGSCR
: :.:. :.: ... .: . . . :::. . .: . :
XP_011 -----------VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLA---LPAIDGLDSTT
990 1000 1010 1020 1030
1030 1040 1050 1060 1070 1080
pF1KE3 QVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNE
:. . ....... :::.. :.: :. :. :. :.: ...: ..
XP_011 CVH------GASFSDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTHSDR
1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 VIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
:::.:::: :::: .:. ..:.::.:::.:::.. .: :: ::..:. ..:::::.:
XP_011 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLAL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVH
.:: : :: : :.:::: :::: .:::. .::::::::.::::::.::.::: .::::
XP_011 IGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT
:::::::::
XP_011 RDLAARNCMYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPATYMNLGPST
1210 1220 1230 1240 1250 1260
1390 residues in 1 query sequences
64236559 residues in 92054 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Aug 1 17:00:18 2019 done: Thu Aug 1 17:00:19 2019
Total Scan time: 7.390 Total Display time: 0.380
Function used was FASTA [36.3.4 Apr, 2011]