FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3504, 863 aa 1>>>pF1KE3504 863 - 863 aa - 863 aa Library: /omim/omim.rfq.tfa 65951994 residues in 93482 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7055+/-0.000348; mu= 19.2791+/- 0.022 mean_var=86.7005+/-17.673, 0's: 0 Z-trim(114.6): 149 B-trim: 487 in 1/50 Lambda= 0.137741 statistics sampled from 25512 (25696) to 25512 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.275), width: 16 Scan time: 5.810 The best scores are: opt bits E(93482) NP_003931 (OMIM: 603591) ubiquitin carboxyl-termin ( 863) 5891 1181.4 0 XP_016862914 (OMIM: 603591) ubiquitin carboxyl-ter ( 833) 5497 1103.0 0 XP_016862915 (OMIM: 603591) ubiquitin carboxyl-ter ( 821) 5206 1045.2 0 XP_016862916 (OMIM: 603591) ubiquitin carboxyl-ter ( 711) 4803 965.1 0 XP_011511571 (OMIM: 603591) ubiquitin carboxyl-ter ( 854) 4373 879.7 0 NP_001092006 (OMIM: 601447) ubiquitin carboxyl-ter ( 858) 3301 666.7 1.4e-190 NP_003472 (OMIM: 601447) ubiquitin carboxyl-termin ( 835) 2713 549.8 2.1e-155 NP_001332954 (OMIM: 618439) ubiquitin carboxyl-ter ( 755) 181 46.6 0.00056 NP_001332953 (OMIM: 618439) ubiquitin carboxyl-ter ( 756) 179 46.2 0.00074 NP_001273006 (OMIM: 616378) UBX domain-containing ( 297) 159 42.0 0.0056 XP_016873363 (OMIM: 616378) UBX domain-containing ( 297) 159 42.0 0.0056 NP_001332959 (OMIM: 618439) ubiquitin carboxyl-ter ( 437) 161 42.5 0.0057 XP_016866875 (OMIM: 618439) ubiquitin carboxyl-ter ( 440) 161 42.5 0.0057 XP_016866874 (OMIM: 618439) ubiquitin carboxyl-ter ( 440) 161 42.5 0.0057 XP_005274090 (OMIM: 616378) UBX domain-containing ( 312) 159 42.0 0.0058 NP_056937 (OMIM: 616378) UBX domain-containing pro ( 312) 159 42.0 0.0058 NP_001332952 (OMIM: 618439) ubiquitin carboxyl-ter ( 813) 163 43.1 0.0071 NP_001332955 (OMIM: 618439) ubiquitin carboxyl-ter ( 721) 161 42.6 0.0085 NP_001073950 (OMIM: 618439) ubiquitin carboxyl-ter ( 814) 161 42.7 0.0093 NP_001332950 (OMIM: 618439) ubiquitin carboxyl-ter ( 814) 161 42.7 0.0093 NP_001332951 (OMIM: 618439) ubiquitin carboxyl-ter ( 814) 161 42.7 0.0093 XP_005267227 (OMIM: 618439) ubiquitin carboxyl-ter ( 814) 161 42.7 0.0093 >>NP_003931 (OMIM: 603591) ubiquitin carboxyl-terminal h (863 aa) initn: 5891 init1: 5891 opt: 5891 Z-score: 6324.7 bits: 1181.4 E(93482): 0 Smith-Waterman score: 5891; 100.0% identity (100.0% similar) in 863 aa overlap (1-863:1-863) 10 20 30 40 50 60 pF1KE3 MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE3 IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE3 FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE3 VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE3 LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE3 ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE3 ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH 790 800 810 820 830 840 850 860 pF1KE3 KVCASERPPKDLGYMYFYRRIPS ::::::::::::::::::::::: NP_003 KVCASERPPKDLGYMYFYRRIPS 850 860 >>XP_016862914 (OMIM: 603591) ubiquitin carboxyl-termina (833 aa) initn: 5497 init1: 5497 opt: 5497 Z-score: 5901.7 bits: 1103.0 E(93482): 0 Smith-Waterman score: 5497; 100.0% identity (100.0% similar) in 807 aa overlap (57-863:27-833) 30 40 50 60 70 80 pF1KE3 LLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEGGLYVCMNTFLAFGREHVERHFRKTGQ :::::::::::::::::::::::::::::: XP_016 MKYKSSLFRTARCRSFASSAGQSAGRNSEGGLYVCMNTFLAFGREHVERHFRKTGQ 10 20 30 40 50 90 100 110 120 130 140 pF1KE3 SVYMHLKRHVREKVRGASGGALPKRRNSKIFLDLDTDDDLNSDDYEYEDEAKLVIFPDHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVYMHLKRHVREKVRGASGGALPKRRNSKIFLDLDTDDDLNSDDYEYEDEAKLVIFPDHY 60 70 80 90 100 110 150 160 170 180 190 200 pF1KE3 EIALPNIEELPALVTIACDAVLSSKSPYRKQDPDTWENELPVSKYANNLTQLDNGVRIPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIALPNIEELPALVTIACDAVLSSKSPYRKQDPDTWENELPVSKYANNLTQLDNGVRIPP 120 130 140 150 160 170 210 220 230 240 250 260 pF1KE3 SGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAVKLGTITPD 180 190 200 210 220 230 270 280 290 300 310 320 pF1KE3 GADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLRVSEWEVIQESGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKLRVSEWEVIQESGTK 240 250 260 270 280 290 330 340 350 360 370 380 pF1KE3 LKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQ 300 310 320 330 340 350 390 400 410 420 430 440 pF1KE3 MTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQ 360 370 380 390 400 410 450 460 470 480 490 500 pF1KE3 DAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAME 420 430 440 450 460 470 510 520 530 540 550 560 pF1KE3 AATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDDFWSSALQAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDDFWSSALQAKS 480 490 500 510 520 530 570 580 590 600 610 620 pF1KE3 AGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMPDLLDINHLRARGLQPGEEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMPDLLDINHLRARGLQPGEEEL 540 550 560 570 580 590 630 640 650 660 670 680 pF1KE3 PDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQLAEMGFPLEACRKAVYFTGNMGAEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQLAEMGFPLEACRKAVYFTGNMGAEVA 600 610 620 630 640 650 690 700 710 720 730 740 pF1KE3 FNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGASGLDNQPPEEIVAIITSMGFQRNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGASGLDNQPPEEIVAIITSMGFQRNQA 660 670 680 690 700 710 750 760 770 780 790 800 pF1KE3 IQALRATNNNLERALDWIFSHPEFEEDSDFVIEMENNANANIISEAKPEGPRVKDGSGTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQALRATNNNLERALDWIFSHPEFEEDSDFVIEMENNANANIISEAKPEGPRVKDGSGTY 720 730 740 750 760 770 810 820 830 840 850 860 pF1KE3 ELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKVCASERPPKDLGYMYFYRRIPS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKVCASERPPKDLGYMYFYRRIPS 780 790 800 810 820 830 >>XP_016862915 (OMIM: 603591) ubiquitin carboxyl-termina (821 aa) initn: 5206 init1: 5206 opt: 5206 Z-score: 5589.3 bits: 1045.2 E(93482): 0 Smith-Waterman score: 5506; 95.1% identity (95.1% similar) in 863 aa overlap (1-863:1-821) 10 20 30 40 50 60 pF1KE3 MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSP---- 10 20 30 40 50 70 80 90 100 110 120 pF1KE3 GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDL :::::::::::::::::::::: XP_016 --------------------------------------KVRGASGGALPKRRNSKIFLDL 60 70 130 140 150 160 170 180 pF1KE3 DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD 80 90 100 110 120 130 190 200 210 220 230 240 pF1KE3 TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG 140 150 160 170 180 190 250 260 270 280 290 300 pF1KE3 GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG 200 210 220 230 240 250 310 320 330 340 350 360 pF1KE3 TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF 260 270 280 290 300 310 370 380 390 400 410 420 pF1KE3 QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ 320 330 340 350 360 370 430 440 450 460 470 480 pF1KE3 QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER 380 390 400 410 420 430 490 500 510 520 530 540 pF1KE3 IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP 440 450 460 470 480 490 550 560 570 580 590 600 pF1KE3 FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD 500 510 520 530 540 550 610 620 630 640 650 660 pF1KE3 VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQ 560 570 580 590 600 610 670 680 690 700 710 720 pF1KE3 LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG 620 630 640 650 660 670 730 740 750 760 770 780 pF1KE3 ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM 680 690 700 710 720 730 790 800 810 820 830 840 pF1KE3 ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH 740 750 760 770 780 790 850 860 pF1KE3 KVCASERPPKDLGYMYFYRRIPS ::::::::::::::::::::::: XP_016 KVCASERPPKDLGYMYFYRRIPS 800 810 820 >>XP_016862916 (OMIM: 603591) ubiquitin carboxyl-termina (711 aa) initn: 4803 init1: 4803 opt: 4803 Z-score: 5157.4 bits: 965.1 E(93482): 0 Smith-Waterman score: 4803; 100.0% identity (100.0% similar) in 704 aa overlap (160-863:8-711) 130 140 150 160 170 180 pF1KE3 DYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPDTWENELPVS :::::::::::::::::::::::::::::: XP_016 MRMALCQVTIACDAVLSSKSPYRKQDPDTWENELPVS 10 20 30 190 200 210 220 230 240 pF1KE3 KYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHY 40 50 60 70 80 90 250 260 270 280 290 300 pF1KE3 RDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDND 100 110 120 130 140 150 310 320 330 340 350 360 pF1KE3 IKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLP 160 170 180 190 200 210 370 380 390 400 410 420 pF1KE3 RIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMF 220 230 240 250 260 270 430 440 450 460 470 480 pF1KE3 KAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKV 280 290 300 310 320 330 490 500 510 520 530 540 pF1KE3 RYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFS 340 350 360 370 380 390 550 560 570 580 590 600 pF1KE3 EPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMPDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMPDLL 400 410 420 430 440 450 610 620 630 640 650 660 pF1KE3 DINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQLAEMGFPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQLAEMGFPLE 460 470 480 490 500 510 670 680 690 700 710 720 pF1KE3 ACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGASGLDNQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGASGLDNQPP 520 530 540 550 560 570 730 740 750 760 770 780 pF1KE3 EEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEMENNANANII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEMENNANANII 580 590 600 610 620 630 790 800 810 820 830 840 pF1KE3 SEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKVCASERPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHKVCASERPP 640 650 660 670 680 690 850 860 pF1KE3 KDLGYMYFYRRIPS :::::::::::::: XP_016 KDLGYMYFYRRIPS 700 710 >>XP_011511571 (OMIM: 603591) ubiquitin carboxyl-termina (854 aa) initn: 4373 init1: 4373 opt: 4373 Z-score: 4694.4 bits: 879.7 E(93482): 0 Smith-Waterman score: 5793; 98.8% identity (98.8% similar) in 863 aa overlap (1-863:1-854) 10 20 30 40 50 60 pF1KE3 MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TWENELPVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TENGLQDNDIKLRVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEER 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE3 IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE3 FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE3 VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQ :::::::::::::::::::::::::::::::::::::::: :::::::::: XP_011 VSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSK---------ASDIDESSVMQ 610 620 630 640 650 670 680 690 700 710 720 pF1KE3 LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFG 660 670 680 690 700 710 730 740 750 760 770 780 pF1KE3 ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM 720 730 740 750 760 770 790 800 810 820 830 840 pF1KE3 ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDH 780 790 800 810 820 830 850 860 pF1KE3 KVCASERPPKDLGYMYFYRRIPS ::::::::::::::::::::::: XP_011 KVCASERPPKDLGYMYFYRRIPS 840 850 >>NP_001092006 (OMIM: 601447) ubiquitin carboxyl-termina (858 aa) initn: 3463 init1: 1583 opt: 3301 Z-score: 3543.1 bits: 666.7 E(93482): 1.4e-190 Smith-Waterman score: 3598; 60.6% identity (84.0% similar) in 862 aa overlap (26-863:7-858) 10 20 30 40 50 60 pF1KE3 MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG : :. .::::::..::::.:.:::::.:.:.::: NP_001 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEG 10 20 30 40 70 80 90 100 110 pF1KE3 GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRG-ASG-GALPKRRNSKIFL :::.::::::.::...::::: :::: ::.::.: : : . :.: : :... ... . NP_001 GLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE3 DLDTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALV----TIACDAVLSSKSPY .. ::. . .: ....:.::.::. ::: .. :: .: : : .:.::. : NP_001 GVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSAS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE3 RKQDPDTWENEL-PVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGK :::. ..:..:. :::.: .: :::: .:::: ::::..::.::::::::::::.:::. NP_001 RKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGR 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE3 WFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGI .::.::::.::.::::. ::::::::::::::::::::..:.. :::: ::.::.:::: NP_001 RYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGI 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE3 DMLHMHGTENGLQDNDIKL--RVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVM :::.:. :.. . . .: . :..:::.:::::. :::..::::::..::::::::.::. NP_001 DMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVV 290 300 310 320 330 340 360 370 380 390 400 410 pF1KE3 QAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQ :..::::.::: :: .: .::. .: ::::::.::..:::::::::.:::: .: :. NP_001 QVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGER 350 360 370 380 390 400 420 430 440 450 460 470 pF1KE3 VMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSD : :.: :.::.::::::...:.:::::.:::::::::::::.:.:::: .::::.. NP_001 V--PEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNE 410 420 430 440 450 480 490 500 510 520 530 pF1KE3 VFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPL ::::::::.:.: :.::.::.::::.::::: :.:: ::.::. :: .:.:: .. : NP_001 VFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMAL 460 470 480 490 500 510 540 550 560 570 580 590 pF1KE3 PELVRAKIPFSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFG ::::::..:::.::.:.. ::.::::::.::::::..:::.::::::.:::.:::::::: NP_001 PELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFG 520 530 540 550 560 570 600 610 620 630 640 pF1KE3 LDWVPKKFDVSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLM---NQLI :::::::.::::.::. :::..::. ::::::::::::.::.: ::. : : :. NP_001 LDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDE 580 590 600 610 620 630 650 660 670 680 690 pF1KE3 D---------PSD--IDESSVMQLAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEP : :.. .::: ..::.:::::..:::::::.::: :::.:.::.. ::..: NP_001 DSFCSPHFSSPTSPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDP 640 650 660 670 680 690 700 710 720 730 740 750 pF1KE3 DFAEPLTMPGYGGAASAGASVFGASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNL :::.:: .:: .: .:..:.. . :::. :. :.::::.:.::..:::::::.: NP_001 DFANPLILPGSSGPGSTSAAA-------DPPPEDCVTTIVSMGFSRDQALKALRATNNSL 700 710 720 730 740 750 760 770 780 790 800 810 pF1KE3 ERALDWIFSHPEFEEDSDFVIEM-ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMG :::.:::::: . . :.. .... :. . :. :::. : ::.:.:: : :.::::::::: NP_001 ERAVDWIFSHID-DLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMG 760 770 780 790 800 810 820 830 840 850 860 pF1KE3 TSTMSGHYICHIKKEGRWVIYNDHKVCASERPPKDLGYMYFYRRIPS :::: :::.::::::::::::::.::::::.:::::::.:::.:. : NP_001 TSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPPKDLGYIYFYQRVAS 820 830 840 850 >>NP_003472 (OMIM: 601447) ubiquitin carboxyl-terminal h (835 aa) initn: 3402 init1: 1580 opt: 2713 Z-score: 2911.8 bits: 549.8 E(93482): 2.1e-155 Smith-Waterman score: 3606; 61.1% identity (84.7% similar) in 848 aa overlap (26-863:7-835) 10 20 30 40 50 60 pF1KE3 MQRRGALFGMPGGSGGRKMAAGDIGELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEG : :. .::::::..::::.:.:::::.:.:.::: NP_003 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEG 10 20 30 40 70 80 90 100 110 pF1KE3 GLYVCMNTFLAFGREHVERHFRKTGQSVYMHLKRHVREKVRG-ASG-GALPKRRNSKIFL :::.::::::.::...::::: :::: ::.::.: : : . :.: : :... ... . NP_003 GLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAI 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE3 DLDTDDDLNSDDYEYEDEAKLVIFPDHYEIALPNIEELPALV----TIACDAVLSSKSPY .. ::. . .: ....:.::.::. ::: .. :: .: : : .:.::. : NP_003 GVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSAS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE3 RKQDPDTWENEL-PVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGK :::. ..:..:. :::.: .: :::: .:::: ::::..::.::::::::::::.:::. NP_003 RKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGR 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE3 WFFDSSGGNGHALEHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGI .::.::::.::.::::. ::::::::::::::::::::..:.. :::: ::.::.:::: NP_003 RYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGI 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE3 DMLHMHGTENGLQDNDIKL--RVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVM :::.:. :.. . . .: . :..:::.:::::. :::..::::::..::::::::.::. NP_003 DMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVV 290 300 310 320 330 340 360 370 380 390 400 410 pF1KE3 QAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQ :..::::.::: :: .: .::. .: ::::::.::..:::::::::.:::: .: :. NP_003 QVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGER 350 360 370 380 390 400 420 430 440 450 460 470 pF1KE3 VMKEEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSD : :.: :.::.::::::...:.:::::.:::::::::::::.:.:::: .::::.. NP_003 V--PEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNE 410 420 430 440 450 480 490 500 510 520 530 pF1KE3 VFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPL ::::::::.:.: :.::.::.::::.::::: :.:: ::.::. :: .:.:: .. : NP_003 VFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMAL 460 470 480 490 500 510 540 550 560 570 580 590 pF1KE3 PELVRAKIPFSACLQAFSEPENVDDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFG ::::::..:::.::.:.. ::.::::::.::::::..:::.::::::.:::.:::::::: NP_003 PELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFG 520 530 540 550 560 570 600 610 620 630 640 650 pF1KE3 LDWVPKKFDVSIDMPDLLDINHLRARGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPS :::::::.::::.::. :::..::. ::::::::::::.::.: ::. : .. NP_003 LDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKAPML------- 580 590 600 610 620 630 660 670 680 690 700 710 pF1KE3 DIDESSVMQLAEMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGA ::: ..::.:::::..:::::::.::: :::.:.::.. ::..::::.:: .:: .: NP_003 --DESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGP 640 650 660 670 680 690 720 730 740 750 760 770 pF1KE3 ASAGASVFGASGLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFE .:..:.. . :::. :. :.::::.:.::..:::::::.::::.:::::: . . NP_003 GSTSAAA-------DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHID-D 700 710 720 730 740 780 790 800 810 820 830 pF1KE3 EDSDFVIEM-ENNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKK :.. .... :. . :. :::. : ::.:.:: : :.::::::::::::: :::.::::: NP_003 LDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKK 750 760 770 780 790 800 840 850 860 pF1KE3 EGRWVIYNDHKVCASERPPKDLGYMYFYRRIPS :::::::::.::::::.:::::::.:::.:. : NP_003 EGRWVIYNDQKVCASEKPPKDLGYIYFYQRVAS 810 820 830 >>NP_001332954 (OMIM: 618439) ubiquitin carboxyl-termina (755 aa) initn: 165 init1: 74 opt: 181 Z-score: 193.1 bits: 46.6 E(93482): 0.00056 Smith-Waterman score: 207; 24.2% identity (57.5% similar) in 339 aa overlap (170-481:17-330) 140 150 160 170 180 190 pF1KE3 VIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPDTWENELPVS-KYANNLTQL :: : .: :. .. .. ..... .. NP_001 MRVKDPTKALPEKAKRSKRPTVPHDEDSSDDIAGLTCQHVSHAISV 10 20 30 40 200 210 220 230 240 pF1KE3 DNGVR-IPPSGWK-CARCDLRENLW----LNLTDGSVLCGKWFFDSSGGNG---HALEHY .. : : . :. :..: :.: . : ::. :: : :.. : :. :.:.:. NP_001 NHVKRAIAENLWSVCSEC-LKERRFYDGQLVLTSDIWLCLKCGFQGCGKNSESQHSLKHF 50 60 70 80 90 100 250 260 270 280 290 300 pF1KE3 ---RDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG--TENG : . . ..:.: .. .. .: :. : :.. .:.:. :. :... NP_001 KSSRTEPHCIIINLSTWI-----IWCYECDEK-LSTHCNKKVLAQIVDFLQKHASKTQTS 110 120 130 140 150 310 320 330 340 350 pF1KE3 LQDNDIKL--RVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAI---FSIPE . .:: . : . ::..: : . . . :. ::::.:....::: . ... . NP_001 AFSRIMKLCEEKCETDEIQKGG-KCRNL---SVRGITNLGNTCFFNAVMQNLAQTYTLTD 160 170 180 190 200 210 360 370 380 390 400 410 pF1KE3 FQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKP-PVKSELIE--QVMKEE .. . .. . :..: .:. : . :.: :. : :. . ::: NP_001 LMNEIKESSTKLKIF----PSSD--SQLDPL-----VVELSRPGPLTSALFLFLHSMKET 220 230 240 250 260 420 430 440 450 460 470 pF1KE3 HKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLV--ERNRIGS-ENPS-DV .: . .::... . .. :.:.. .:::.::.. .:.. : :...:.. ..: :. NP_001 EK---GPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKISTVKDPFIDI 270 280 290 300 310 320 480 490 500 510 520 530 pF1KE3 FRFLVEERIQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRPLP ..:::. NP_001 SLPIIEERVSKPLLWGRMNKYRSLRETDHDRYSGNVTIENIHQPRAAKKHSSSKDKSQLI 330 340 350 360 370 380 >>NP_001332953 (OMIM: 618439) ubiquitin carboxyl-termina (756 aa) initn: 165 init1: 74 opt: 179 Z-score: 191.0 bits: 46.2 E(93482): 0.00074 Smith-Waterman score: 205; 24.3% identity (57.5% similar) in 341 aa overlap (170-481:17-331) 140 150 160 170 180 190 pF1KE3 VIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQDPDTWENELPVS---KYANNLT :: : .: :. ... :. ..... NP_001 MRVKDPTKALPEKAKRSKRPTVPHDEDS-SDDIAVGLTCQHVSHAI 10 20 30 40 200 210 220 230 240 pF1KE3 QLDNGVR-IPPSGWK-CARCDLRENLW----LNLTDGSVLCGKWFFDSSGGNG---HALE .... : : . :. :..: :.: . : ::. :: : :.. : :. :.:. NP_001 SVNHVKRAIAENLWSVCSEC-LKERRFYDGQLVLTSDIWLCLKCGFQGCGKNSESQHSLK 50 60 70 80 90 100 250 260 270 280 290 300 pF1KE3 HY---RDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHG--TE :. : . . ..:.: .. .. .: :. : :.. .:.:. :. :. NP_001 HFKSSRTEPHCIIINLSTWI-----IWCYECDEK-LSTHCNKKVLAQIVDFLQKHASKTQ 110 120 130 140 150 310 320 330 340 350 pF1KE3 NGLQDNDIKL--RVSEWEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAI---FSI .. . .:: . : . ::..: : . . . :. ::::.:....::: . ... NP_001 TSAFSRIMKLCEEKCETDEIQKGG-KCRNL---SVRGITNLGNTCFFNAVMQNLAQTYTL 160 170 180 190 200 210 360 370 380 390 400 410 pF1KE3 PEFQRAYVGNLPRIFDYSPLDPTQDFNTQMTKLGHGLLSGQYSKP-PVKSELIE--QVMK ... . .. . :..: .:. : . :.: :. : :. . :: NP_001 TDLMNEIKESSTKLKIF----PSSD--SQLDPL-----VVELSRPGPLTSALFLFLHSMK 220 230 240 250 260 420 430 440 450 460 470 pF1KE3 EEHKPQQNGISPRMFKAFVSKSHPEFSSNRQQDAQEFFLHLVNLV--ERNRIGS-ENPS- : .: . .::... . .. :.:.. .:::.::.. .:.. : :...:.. ..: NP_001 ETEK---GPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKISTVKDPFI 270 280 290 300 310 320 480 490 500 510 520 530 pF1KE3 DVFRFLVEERIQCCQTRKVRYTERVDYLMQLPVAMEAATNKDELIAYELTRREAEANRRP :. ..:::. NP_001 DISLPIIEERVSKPLLWGRMNKYRSLRETDHDRYSGNVTIENIHQPRAAKKHSSSKDKSQ 330 340 350 360 370 380 >>NP_001273006 (OMIM: 616378) UBX domain-containing prot (297 aa) initn: 180 init1: 153 opt: 159 Z-score: 175.2 bits: 42.0 E(93482): 0.0056 Smith-Waterman score: 159; 43.1% identity (72.5% similar) in 51 aa overlap (656-706:5-55) 630 640 650 660 670 680 pF1KE3 LPDISPPIVIPDDSKDRLMNQLIDPSDIDESSVMQLAEMGFPLEACRKAVYFTGNMGAEV ... .: ::::: .::. .:::.: :. NP_001 MAELTALESLIEMGFPRGRAEKALALTGNQGIEA 10 20 30 690 700 710 720 730 740 pF1KE3 AFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGASGLDNQPPEEIVAIITSMGFQRNQ :..:.. : ..:: ::: : NP_001 AMDWLMEHEDDPDVDEPLETPLGHILGREPTSSEQGGLEGSGSAAGEGKPALSEEERQEQ 40 50 60 70 80 90 863 residues in 1 query sequences 65951994 residues in 93482 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Jun 20 10:38:59 2019 done: Thu Jun 20 10:39:00 2019 Total Scan time: 5.810 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]