FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3523, 349 aa
1>>>pF1KE3523 349 - 349 aa - 349 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8524+/-0.00127; mu= 3.2889+/- 0.073
mean_var=253.6694+/-60.367, 0's: 0 Z-trim(108.3): 639 B-trim: 111 in 1/48
Lambda= 0.080527
statistics sampled from 9321 (10096) to 9321 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.31), width: 16
Scan time: 2.610
The best scores are: opt bits E(32554)
CCDS2350.1 CDK15 gene_id:65061|Hs108|chr2 ( 384) 2365 288.5 6.2e-78
CCDS58746.1 CDK15 gene_id:65061|Hs108|chr2 ( 400) 2365 288.5 6.4e-78
CCDS58747.1 CDK15 gene_id:65061|Hs108|chr2 ( 429) 2359 287.9 1.1e-77
CCDS75627.1 CDK14 gene_id:5218|Hs108|chr7 ( 423) 1473 184.9 1e-46
CCDS5619.1 CDK14 gene_id:5218|Hs108|chr7 ( 451) 1473 185.0 1.1e-46
CCDS75626.1 CDK14 gene_id:5218|Hs108|chr7 ( 469) 1473 185.0 1.1e-46
CCDS75628.1 CDK14 gene_id:5218|Hs108|chr7 ( 340) 1352 170.7 1.5e-42
CCDS14276.1 CDK16 gene_id:5127|Hs108|chrX ( 496) 1141 146.4 4.7e-35
CCDS48101.1 CDK16 gene_id:5127|Hs108|chrX ( 502) 1141 146.4 4.7e-35
CCDS55408.1 CDK16 gene_id:5127|Hs108|chrX ( 570) 1141 146.5 5.1e-35
CCDS44300.1 CDK18 gene_id:5129|Hs108|chr1 ( 474) 1122 144.2 2.1e-34
CCDS1454.1 CDK18 gene_id:5129|Hs108|chr1 ( 504) 1122 144.2 2.2e-34
CCDS9061.1 CDK17 gene_id:5128|Hs108|chr12 ( 523) 1122 144.3 2.2e-34
CCDS53819.1 CDK17 gene_id:5128|Hs108|chr12 ( 523) 1122 144.3 2.2e-34
CCDS47748.1 CDK5 gene_id:1020|Hs108|chr7 ( 292) 974 126.8 2.3e-29
CCDS11736.1 CDK3 gene_id:1018|Hs108|chr17 ( 305) 963 125.5 5.8e-29
CCDS8898.1 CDK2 gene_id:1017|Hs108|chr12 ( 298) 890 117.0 2e-26
CCDS44408.1 CDK1 gene_id:983|Hs108|chr10 ( 297) 837 110.8 1.4e-24
CCDS3999.1 CDK7 gene_id:1022|Hs108|chr5 ( 346) 727 98.1 1.1e-20
CCDS72682.1 CDK11B gene_id:984|Hs108|chr1 ( 748) 727 98.6 1.8e-20
CCDS72684.1 CDK11B gene_id:984|Hs108|chr1 ( 782) 727 98.6 1.9e-20
CCDS72683.1 CDK11B gene_id:984|Hs108|chr1 ( 795) 727 98.6 1.9e-20
CCDS44043.1 CDK11A gene_id:728642|Hs108|chr1 ( 770) 719 97.6 3.5e-20
CCDS81254.1 CDK11A gene_id:728642|Hs108|chr1 ( 779) 719 97.6 3.6e-20
CCDS44042.1 CDK11A gene_id:728642|Hs108|chr1 ( 780) 719 97.6 3.6e-20
CCDS81253.1 CDK11A gene_id:728642|Hs108|chr1 ( 783) 719 97.7 3.6e-20
CCDS35060.1 CDK20 gene_id:23552|Hs108|chr9 ( 346) 684 93.2 3.6e-19
CCDS10984.2 CDK10 gene_id:8558|Hs108|chr16 ( 360) 661 90.5 2.3e-18
CCDS4949.1 ICK gene_id:22858|Hs108|chr6 ( 632) 638 88.1 2.1e-17
CCDS75398.1 MAK gene_id:4117|Hs108|chr6 ( 583) 637 88.0 2.2e-17
CCDS4516.1 MAK gene_id:4117|Hs108|chr6 ( 623) 637 88.0 2.3e-17
CCDS75399.1 MAK gene_id:4117|Hs108|chr6 ( 648) 637 88.0 2.3e-17
CCDS3570.1 CDKL2 gene_id:8999|Hs108|chr4 ( 493) 610 84.7 1.7e-16
CCDS82933.1 CDKL2 gene_id:8999|Hs108|chr4 ( 570) 610 84.8 1.9e-16
CCDS47265.1 CDKL3 gene_id:51265|Hs108|chr5 ( 455) 604 84.0 2.7e-16
CCDS47264.1 CDKL3 gene_id:51265|Hs108|chr5 ( 592) 604 84.1 3.1e-16
CCDS13795.1 MAPK1 gene_id:5594|Hs108|chr22 ( 360) 597 83.1 4e-16
CCDS33184.1 CDKL4 gene_id:344387|Hs108|chr2 ( 315) 593 82.5 5.1e-16
CCDS32514.2 CDK10 gene_id:8558|Hs108|chr16 ( 272) 590 82.1 5.9e-16
CCDS42149.1 MAPK3 gene_id:5595|Hs108|chr16 ( 357) 581 81.2 1.5e-15
CCDS10672.1 MAPK3 gene_id:5595|Hs108|chr16 ( 379) 581 81.2 1.5e-15
CCDS5628.1 CDK6 gene_id:1021|Hs108|chr7 ( 326) 576 80.6 2.1e-15
CCDS6879.1 CDK9 gene_id:1025|Hs108|chr9 ( 372) 576 80.6 2.2e-15
CCDS83458.1 CDKL5 gene_id:6792|Hs108|chrX ( 960) 577 81.3 3.8e-15
CCDS14186.1 CDKL5 gene_id:6792|Hs108|chrX (1030) 577 81.3 3.9e-15
CCDS11206.1 MAPK7 gene_id:5598|Hs108|chr17 ( 816) 575 80.9 4e-15
CCDS9699.1 CDKL1 gene_id:8814|Hs108|chr14 ( 358) 567 79.6 4.5e-15
CCDS8953.1 CDK4 gene_id:1019|Hs108|chr12 ( 303) 559 78.6 7.7e-15
CCDS8899.1 CDK2 gene_id:1017|Hs108|chr12 ( 264) 541 76.4 3e-14
CCDS73637.1 CDKL1 gene_id:8814|Hs108|chr14 ( 276) 541 76.4 3.1e-14
>>CCDS2350.1 CDK15 gene_id:65061|Hs108|chr2 (384 aa)
initn: 2365 init1: 2365 opt: 2365 Z-score: 1512.6 bits: 288.5 E(32554): 6.2e-78
Smith-Waterman score: 2365; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 GSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 ETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 ISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 EMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVW
250 260 270 280 290 300
310 320 330 340
pF1KE3 NRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 NRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRL
310 320 330 340 350 360
CCDS23 KPEMCDLLASYQKGHHPAQFSKCW
370 380
>>CCDS58746.1 CDK15 gene_id:65061|Hs108|chr2 (400 aa)
initn: 2365 init1: 2365 opt: 2365 Z-score: 1512.4 bits: 288.5 E(32554): 6.4e-78
Smith-Waterman score: 2365; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:52-400)
10 20 30
pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQ
::::::::::::::::::::::::::::::
CCDS58 GGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQ
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE3 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE3 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA
330 340 350 360 370 380
340
pF1KE3 LVHDYFSALPSQLYQLPDE
:::::::::::::::::::
CCDS58 LVHDYFSALPSQLYQLPDE
390 400
>>CCDS58747.1 CDK15 gene_id:65061|Hs108|chr2 (429 aa)
initn: 2359 init1: 2359 opt: 2359 Z-score: 1508.3 bits: 287.9 E(32554): 1.1e-77
Smith-Waterman score: 2359; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:52-399)
10 20 30
pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQ
::::::::::::::::::::::::::::::
CCDS58 GGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQ
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE3 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE3 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA
330 340 350 360 370 380
340
pF1KE3 LVHDYFSALPSQLYQLPDE
::::::::::::::::::
CCDS58 LVHDYFSALPSQLYQLPDVSGVRLKPEMCDLLASYQKGHHPAQFSKCW
390 400 410 420
>>CCDS75627.1 CDK14 gene_id:5218|Hs108|chr7 (423 aa)
initn: 1473 init1: 1473 opt: 1473 Z-score: 952.1 bits: 184.9 E(32554): 1e-46
Smith-Waterman score: 1473; 70.6% identity (90.1% similar) in 303 aa overlap (46-348:83-385)
20 30 40 50 60 70
pF1KE3 KFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRING
:: :.:: .::::::::::::::: :..::
CCDS75 ACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNG
60 70 80 90 100 110
80 90 100 110 120 130
pF1KE3 QLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLA
.::::::: .. :::.:::::::::::::::::::::::::::::::::.::::.::::
CCDS75 KLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLC
120 130 140 150 160 170
140 150 160 170 180 190
pF1KE3 QYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLA
:::..::::::: ::.::.:::::::.:::....::::::::::::: :::::::::::
CCDS75 QYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLA
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE3 RAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNI
::::.::.:::.:::::::::::.:::.::::. ::.::.::::.::.:: :::...:
CCDS75 RAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDI
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE3 LEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQ
.:::.:. :::.:.::::::: .::...:: : : . ..:. .::.:. : .::::::.
CCDS75 QDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASK
300 310 320 330 340 350
320 330 340
pF1KE3 MLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE
.:. :..:.::: :: :.::: :: .:..: :
CCDS75 LLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNN
360 370 380 390 400 410
CCDS75 SYGKSLSNSKH
420
>>CCDS5619.1 CDK14 gene_id:5218|Hs108|chr7 (451 aa)
initn: 1473 init1: 1473 opt: 1473 Z-score: 951.8 bits: 185.0 E(32554): 1.1e-46
Smith-Waterman score: 1473; 70.6% identity (90.1% similar) in 303 aa overlap (46-348:111-413)
20 30 40 50 60 70
pF1KE3 KFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRING
:: :.:: .::::::::::::::: :..::
CCDS56 ACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNG
90 100 110 120 130 140
80 90 100 110 120 130
pF1KE3 QLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLA
.::::::: .. :::.:::::::::::::::::::::::::::::::::.::::.::::
CCDS56 KLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLC
150 160 170 180 190 200
140 150 160 170 180 190
pF1KE3 QYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLA
:::..::::::: ::.::.:::::::.:::....::::::::::::: :::::::::::
CCDS56 QYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLA
210 220 230 240 250 260
200 210 220 230 240 250
pF1KE3 RAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNI
::::.::.:::.:::::::::::.:::.::::. ::.::.::::.::.:: :::...:
CCDS56 RAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDI
270 280 290 300 310 320
260 270 280 290 300 310
pF1KE3 LEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQ
.:::.:. :::.:.::::::: .::...:: : : . ..:. .::.:. : .::::::.
CCDS56 QDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASK
330 340 350 360 370 380
320 330 340
pF1KE3 MLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE
.:. :..:.::: :: :.::: :: .:..: :
CCDS56 LLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNN
390 400 410 420 430 440
CCDS56 SYGKSLSNSKH
450
>>CCDS75626.1 CDK14 gene_id:5218|Hs108|chr7 (469 aa)
initn: 1473 init1: 1473 opt: 1473 Z-score: 951.6 bits: 185.0 E(32554): 1.1e-46
Smith-Waterman score: 1473; 70.6% identity (90.1% similar) in 303 aa overlap (46-348:129-431)
20 30 40 50 60 70
pF1KE3 KFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRING
:: :.:: .::::::::::::::: :..::
CCDS75 ACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNG
100 110 120 130 140 150
80 90 100 110 120 130
pF1KE3 QLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLA
.::::::: .. :::.:::::::::::::::::::::::::::::::::.::::.::::
CCDS75 KLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLC
160 170 180 190 200 210
140 150 160 170 180 190
pF1KE3 QYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLA
:::..::::::: ::.::.:::::::.:::....::::::::::::: :::::::::::
CCDS75 QYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLA
220 230 240 250 260 270
200 210 220 230 240 250
pF1KE3 RAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNI
::::.::.:::.:::::::::::.:::.::::. ::.::.::::.::.:: :::...:
CCDS75 RAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDI
280 290 300 310 320 330
260 270 280 290 300 310
pF1KE3 LEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQ
.:::.:. :::.:.::::::: .::...:: : : . ..:. .::.:. : .::::::.
CCDS75 QDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASK
340 350 360 370 380 390
320 330 340
pF1KE3 MLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE
.:. :..:.::: :: :.::: :: .:..: :
CCDS75 LLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNN
400 410 420 430 440 450
CCDS75 SYGKSLSNSKH
460
>>CCDS75628.1 CDK14 gene_id:5218|Hs108|chr7 (340 aa)
initn: 1340 init1: 1340 opt: 1352 Z-score: 877.2 bits: 170.7 E(32554): 1.5e-42
Smith-Waterman score: 1353; 66.8% identity (86.5% similar) in 304 aa overlap (45-348:8-302)
20 30 40 50 60 70
pF1KE3 QKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRIN
: :.:.: ::: :. : .:.:
CCDS75 MLALTLRPPPLAKSHL---KLG-GTPAP-----ARVN
10 20
80 90 100 110 120 130
pF1KE3 GQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDL
:.::::::: .. :::.:::::::::::::::::::::::::::::::::.::::.::::
CCDS75 GKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDL
30 40 50 60 70 80
140 150 160 170 180 190
pF1KE3 AQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGL
:::..::::::: ::.::.:::::::.:::....::::::::::::: ::::::::::
CCDS75 CQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGL
90 100 110 120 130 140
200 210 220 230 240 250
pF1KE3 ARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSN
:::::.::.:::.:::::::::::.:::.::::. ::.::.::::.::.:: :::...
CCDS75 ARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKD
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE3 ILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLAS
: .:::.:. :::.:.::::::: .::...:: : : . ..:. .::.:. : .::::::
CCDS75 IQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLAS
210 220 230 240 250 260
320 330 340
pF1KE3 QMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE
..:. :..:.::: :: :.::: :: .:..: :
CCDS75 KLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKN
270 280 290 300 310 320
CCDS75 NSYGKSLSNSKH
330 340
>>CCDS14276.1 CDK16 gene_id:5127|Hs108|chrX (496 aa)
initn: 1145 init1: 955 opt: 1141 Z-score: 742.9 bits: 146.4 E(32554): 4.7e-35
Smith-Waterman score: 1141; 57.2% identity (82.6% similar) in 304 aa overlap (46-348:159-458)
20 30 40 50 60 70
pF1KE3 KFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRING
:: .:..:.:::::.::::::: :...
CCDS14 GYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTD
130 140 150 160 170 180
80 90 100 110 120 130
pF1KE3 QLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLA
.::::: : .. :::.: :::::.:::: ::::::: :::::::...::.::::. ::
CCDS14 NLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLK
190 200 210 220 230 240
140 150 160 170 180 190
pF1KE3 QYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLA
::... . .. :::.::.::::::::: :.:.:::::::::::::.. :::::::::::
CCDS14 QYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLA
250 260 270 280 290 300
200 210 220 230 240 250
pF1KE3 RAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNI
::::::..:::.::::::::::: :::.:.::...:.::.:::: :: :.::::: :..
CCDS14 RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPG-STV
310 320 330 340 350 360
260 270 280 290 300 310
pF1KE3 LEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVP-EAEDLAS
:::. :...::.:::.::::. : : . . . : :. ... .. :. .. :: .
CCDS14 EEQLHFIFRILGTPTEETWPGI--LSNEEFKTYNYPKYRA-EALLSHAPRLDSDGADLLT
370 380 390 400 410 420
320 330 340
pF1KE3 QMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE
..:. :.:.::..:. : .: .: ....:::
CCDS14 KLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDS
430 440 450 460 470 480
CCDS14 GRPAFRVVDTEF
490
>>CCDS48101.1 CDK16 gene_id:5127|Hs108|chrX (502 aa)
initn: 1145 init1: 955 opt: 1141 Z-score: 742.8 bits: 146.4 E(32554): 4.7e-35
Smith-Waterman score: 1141; 57.2% identity (82.6% similar) in 304 aa overlap (46-348:165-464)
20 30 40 50 60 70
pF1KE3 KFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRING
:: .:..:.:::::.::::::: :...
CCDS48 GYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTD
140 150 160 170 180 190
80 90 100 110 120 130
pF1KE3 QLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLA
.::::: : .. :::.: :::::.:::: ::::::: :::::::...::.::::. ::
CCDS48 NLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLK
200 210 220 230 240 250
140 150 160 170 180 190
pF1KE3 QYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLA
::... . .. :::.::.::::::::: :.:.:::::::::::::.. :::::::::::
CCDS48 QYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLA
260 270 280 290 300 310
200 210 220 230 240 250
pF1KE3 RAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNI
::::::..:::.::::::::::: :::.:.::...:.::.:::: :: :.::::: :..
CCDS48 RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPG-STV
320 330 340 350 360 370
260 270 280 290 300 310
pF1KE3 LEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVP-EAEDLAS
:::. :...::.:::.::::. : : . . . : :. ... .. :. .. :: .
CCDS48 EEQLHFIFRILGTPTEETWPGI--LSNEEFKTYNYPKYRA-EALLSHAPRLDSDGADLLT
380 390 400 410 420 430
320 330 340
pF1KE3 QMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE
..:. :.:.::..:. : .: .: ....:::
CCDS48 KLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDS
440 450 460 470 480 490
CCDS48 GRPAFRVVDTEF
500
>>CCDS55408.1 CDK16 gene_id:5127|Hs108|chrX (570 aa)
initn: 1145 init1: 955 opt: 1141 Z-score: 742.2 bits: 146.5 E(32554): 5.1e-35
Smith-Waterman score: 1141; 57.2% identity (82.6% similar) in 304 aa overlap (46-348:233-532)
20 30 40 50 60 70
pF1KE3 KFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRING
:: .:..:.:::::.::::::: :...
CCDS55 GYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTD
210 220 230 240 250 260
80 90 100 110 120 130
pF1KE3 QLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLA
.::::: : .. :::.: :::::.:::: ::::::: :::::::...::.::::. ::
CCDS55 NLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLK
270 280 290 300 310 320
140 150 160 170 180 190
pF1KE3 QYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLA
::... . .. :::.::.::::::::: :.:.:::::::::::::.. :::::::::::
CCDS55 QYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLA
330 340 350 360 370 380
200 210 220 230 240 250
pF1KE3 RAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNI
::::::..:::.::::::::::: :::.:.::...:.::.:::: :: :.::::: :..
CCDS55 RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPG-STV
390 400 410 420 430 440
260 270 280 290 300 310
pF1KE3 LEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVP-EAEDLAS
:::. :...::.:::.::::. : : . . . : :. ... .. :. .. :: .
CCDS55 EEQLHFIFRILGTPTEETWPGI--LSNEEFKTYNYPKYRA-EALLSHAPRLDSDGADLLT
450 460 470 480 490
320 330 340
pF1KE3 QMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE
..:. :.:.::..:. : .: .: ....:::
CCDS55 KLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDS
500 510 520 530 540 550
CCDS55 GRPAFRVVDTEF
560 570
349 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 18 17:33:39 2016 done: Fri Nov 18 17:33:40 2016
Total Scan time: 2.610 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]