FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3523, 349 aa 1>>>pF1KE3523 349 - 349 aa - 349 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.1824+/-0.000607; mu= -30.5546+/- 0.036 mean_var=691.6164+/-151.618, 0's: 0 Z-trim(115.8): 1367 B-trim: 542 in 1/52 Lambda= 0.048769 statistics sampled from 24573 (26522) to 24573 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.311), width: 16 Scan time: 8.100 The best scores are: opt bits E(85289) XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384) 2365 182.2 1.7e-45 NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384) 2365 182.2 1.7e-45 NP_001248365 (OMIM: 616147) cyclin-dependent kinas ( 400) 2365 182.2 1.7e-45 XP_005246838 (OMIM: 616147) PREDICTED: cyclin-depe ( 435) 2365 182.2 1.8e-45 XP_011509952 (OMIM: 616147) PREDICTED: cyclin-depe ( 412) 2359 181.8 2.3e-45 NP_001248364 (OMIM: 616147) cyclin-dependent kinas ( 429) 2359 181.8 2.4e-45 XP_011509954 (OMIM: 616147) PREDICTED: cyclin-depe ( 372) 1931 151.6 2.5e-36 XP_011509956 (OMIM: 616147) PREDICTED: cyclin-depe ( 344) 1919 150.7 4.3e-36 XP_011509957 (OMIM: 616147) PREDICTED: cyclin-depe ( 255) 1529 123.2 6.4e-28 XP_011509958 (OMIM: 616147) PREDICTED: cyclin-depe ( 255) 1529 123.2 6.4e-28 XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1473 119.4 1.4e-26 XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1473 119.4 1.4e-26 XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1473 119.4 1.4e-26 NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423) 1473 119.4 1.4e-26 XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1473 119.4 1.4e-26 XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1473 119.4 1.4e-26 XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450) 1473 119.5 1.5e-26 NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451) 1473 119.5 1.5e-26 NP_001274064 (OMIM: 610679) cyclin-dependent kinas ( 469) 1473 119.5 1.5e-26 XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469) 1473 119.5 1.5e-26 XP_011509959 (OMIM: 616147) PREDICTED: cyclin-depe ( 245) 1372 112.1 1.3e-24 NP_001274066 (OMIM: 610679) cyclin-dependent kinas ( 340) 1352 110.8 4.4e-24 XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1141 96.2 1.7e-19 NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 1141 96.2 1.7e-19 XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1141 96.2 1.7e-19 XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1141 96.2 1.7e-19 XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1141 96.2 1.7e-19 XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1141 96.2 1.7e-19 XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1141 96.2 1.7e-19 XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1141 96.2 1.7e-19 XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1141 96.2 1.7e-19 XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1141 96.2 1.7e-19 NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 1141 96.2 1.7e-19 XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 1141 96.2 1.7e-19 XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 1141 96.2 1.8e-19 XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 1141 96.2 1.8e-19 XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 1141 96.2 1.8e-19 NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 1141 96.2 1.8e-19 XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 1141 96.2 1.8e-19 NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1122 94.8 4.1e-19 NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1122 94.8 4.1e-19 NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 1122 94.8 4.3e-19 XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1122 94.8 4.4e-19 NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 1122 94.8 4.4e-19 XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1122 94.8 4.4e-19 NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 1122 94.8 4.4e-19 XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 1122 94.9 4.5e-19 XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 1122 94.9 4.7e-19 NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 974 84.2 4e-16 NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 963 83.4 7e-16 >>XP_005246839 (OMIM: 616147) PREDICTED: cyclin-dependen (384 aa) initn: 2365 init1: 2365 opt: 2365 Z-score: 937.9 bits: 182.2 E(85289): 1.7e-45 Smith-Waterman score: 2365; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349) 10 20 30 40 50 60 pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 GSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 ETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 ISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 EMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVW 250 260 270 280 290 300 310 320 330 340 pF1KE3 NRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRL 310 320 330 340 350 360 XP_005 KPEMCDLLASYQKGHHPAQFSKCW 370 380 >>NP_631897 (OMIM: 616147) cyclin-dependent kinase 15 is (384 aa) initn: 2365 init1: 2365 opt: 2365 Z-score: 937.9 bits: 182.2 E(85289): 1.7e-45 Smith-Waterman score: 2365; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349) 10 20 30 40 50 60 pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 GSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 GSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 ETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 ETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 ISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 ISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 EMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 EMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVW 250 260 270 280 290 300 310 320 330 340 pF1KE3 NRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE ::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 NRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRL 310 320 330 340 350 360 NP_631 KPEMCDLLASYQKGHHPAQFSKCW 370 380 >>NP_001248365 (OMIM: 616147) cyclin-dependent kinase 15 (400 aa) initn: 2365 init1: 2365 opt: 2365 Z-score: 937.7 bits: 182.2 E(85289): 1.7e-45 Smith-Waterman score: 2365; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:52-400) 10 20 30 pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQ :::::::::::::::::::::::::::::: NP_001 GGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQ 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE3 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE3 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE3 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE3 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT 270 280 290 300 310 320 280 290 300 310 320 330 pF1KE3 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA 330 340 350 360 370 380 340 pF1KE3 LVHDYFSALPSQLYQLPDE ::::::::::::::::::: NP_001 LVHDYFSALPSQLYQLPDE 390 400 >>XP_005246838 (OMIM: 616147) PREDICTED: cyclin-dependen (435 aa) initn: 2365 init1: 2365 opt: 2365 Z-score: 937.2 bits: 182.2 E(85289): 1.8e-45 Smith-Waterman score: 2365; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:52-400) 10 20 30 pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQ :::::::::::::::::::::::::::::: XP_005 GGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQ 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE3 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE3 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE3 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE3 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT 270 280 290 300 310 320 280 290 300 310 320 330 pF1KE3 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA 330 340 350 360 370 380 340 pF1KE3 LVHDYFSALPSQLYQLPDE ::::::::::::::::::: XP_005 LVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKGHHPAQFSKCW 390 400 410 420 430 >>XP_011509952 (OMIM: 616147) PREDICTED: cyclin-dependen (412 aa) initn: 2359 init1: 2359 opt: 2359 Z-score: 935.3 bits: 181.8 E(85289): 2.3e-45 Smith-Waterman score: 2359; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:52-399) 10 20 30 pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQ :::::::::::::::::::::::::::::: XP_011 GGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQ 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE3 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE3 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE3 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE3 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT 270 280 290 300 310 320 280 290 300 310 320 330 pF1KE3 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA 330 340 350 360 370 380 340 pF1KE3 LVHDYFSALPSQLYQLPDE :::::::::::::::::: XP_011 LVHDYFSALPSQLYQLPDVTEPKSTLTLLEK 390 400 410 >>NP_001248364 (OMIM: 616147) cyclin-dependent kinase 15 (429 aa) initn: 2359 init1: 2359 opt: 2359 Z-score: 935.0 bits: 181.8 E(85289): 2.4e-45 Smith-Waterman score: 2359; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:52-399) 10 20 30 pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQ :::::::::::::::::::::::::::::: NP_001 GGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQ 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE3 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE3 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE3 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE3 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT 270 280 290 300 310 320 280 290 300 310 320 330 pF1KE3 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA 330 340 350 360 370 380 340 pF1KE3 LVHDYFSALPSQLYQLPDE :::::::::::::::::: NP_001 LVHDYFSALPSQLYQLPDVSGVRLKPEMCDLLASYQKGHHPAQFSKCW 390 400 410 420 >>XP_011509954 (OMIM: 616147) PREDICTED: cyclin-dependen (372 aa) initn: 1947 init1: 1925 opt: 1931 Z-score: 773.1 bits: 151.6 E(85289): 2.5e-36 Smith-Waterman score: 1931; 92.8% identity (94.7% similar) in 320 aa overlap (1-319:52-362) 10 20 30 pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQ :::::::::::::::::::::::::::::: XP_011 GGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQ 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE3 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE3 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE3 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE3 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT 270 280 290 300 310 320 280 290 300 310 320 pF1KE3 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWN-RLGRVPEAEDLASQMLKGFPRDRVSAQE :::::::::::::::: .:: .: . :: :: :: ... :: XP_011 EDTWPGVSKLPNYNPE-------ESLFTVSGVRLK--PEMCDLLASYQKGHHPAQFSKCW 330 340 350 360 370 330 340 pF1KE3 ALVHDYFSALPSQLYQLPDE >>XP_011509956 (OMIM: 616147) PREDICTED: cyclin-dependen (344 aa) initn: 1919 init1: 1919 opt: 1919 Z-score: 768.9 bits: 150.7 E(85289): 4.3e-36 Smith-Waterman score: 1919; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:52-336) 10 20 30 pF1KE3 MTSFHPRGLQAARAQKFKSKRPRSNSDCFQ :::::::::::::::::::::::::::::: XP_011 GGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQ 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE3 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE3 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE3 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE3 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT 270 280 290 300 310 320 280 290 300 310 320 330 pF1KE3 EDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEA ::::::::::::::: XP_011 EDTWPGVSKLPNYNPAIHRDLAS 330 340 >>XP_011509957 (OMIM: 616147) PREDICTED: cyclin-dependen (255 aa) initn: 1529 init1: 1529 opt: 1529 Z-score: 622.2 bits: 123.2 E(85289): 6.4e-28 Smith-Waterman score: 1529; 100.0% identity (100.0% similar) in 220 aa overlap (130-349:1-220) 100 110 120 130 140 150 pF1KE3 SLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLR :::::::::::::::::::::::::::::: XP_011 MHTDLAQYMSQHPGGLHPHNVRLFMFQLLR 10 20 30 160 170 180 190 200 210 pF1KE3 GLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDA 40 50 60 70 80 90 220 230 240 250 260 270 pF1KE3 LLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSK 100 110 120 130 140 150 280 290 300 310 320 330 pF1KE3 LPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSAL 160 170 180 190 200 210 340 pF1KE3 PSQLYQLPDE :::::::::: XP_011 PSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKGHHPAQFSKCW 220 230 240 250 >>XP_011509958 (OMIM: 616147) PREDICTED: cyclin-dependen (255 aa) initn: 1529 init1: 1529 opt: 1529 Z-score: 622.2 bits: 123.2 E(85289): 6.4e-28 Smith-Waterman score: 1529; 100.0% identity (100.0% similar) in 220 aa overlap (130-349:1-220) 100 110 120 130 140 150 pF1KE3 SLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLR :::::::::::::::::::::::::::::: XP_011 MHTDLAQYMSQHPGGLHPHNVRLFMFQLLR 10 20 30 160 170 180 190 200 210 pF1KE3 GLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDA 40 50 60 70 80 90 220 230 240 250 260 270 pF1KE3 LLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSK 100 110 120 130 140 150 280 290 300 310 320 330 pF1KE3 LPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSAL 160 170 180 190 200 210 340 pF1KE3 PSQLYQLPDE :::::::::: XP_011 PSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKGHHPAQFSKCW 220 230 240 250 349 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 18 17:33:40 2016 done: Fri Nov 18 17:33:41 2016 Total Scan time: 8.100 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]