Result of FASTA (omim) for
pF1KE3542
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3542, 1130 aa
1>>>pF1KE3542 1130 - 1130 aa - 1130 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1456+/-0.000539; mu= 3.3947+/- 0.034
mean_var=700.5581+/-158.596, 0's: 0 Z-trim(120.5): 729 B-trim: 0 in 0/54
Lambda= 0.048457
statistics sampled from 34939 (35737) to 34939 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.419), width: 16
Scan time: 16.650
The best scores are: opt bits E(85289)
NP_001073917 (OMIM: 600066) ephrin type-A receptor (1130) 7746 558.7 7.3e-158
XP_016861699 (OMIM: 600066) PREDICTED: ephrin type (1104) 4033 299.1 9.9e-80
XP_006713655 (OMIM: 600066) PREDICTED: ephrin type (1146) 4033 299.1 1e-79
XP_016861708 (OMIM: 600066) PREDICTED: ephrin type ( 537) 3753 279.0 5.4e-74
XP_016861705 (OMIM: 600066) PREDICTED: ephrin type ( 578) 3720 276.7 2.8e-73
XP_016861704 (OMIM: 600066) PREDICTED: ephrin type ( 594) 3715 276.4 3.6e-73
XP_016861707 (OMIM: 600066) PREDICTED: ephrin type ( 554) 3714 276.3 3.7e-73
XP_016861706 (OMIM: 600066) PREDICTED: ephrin type ( 554) 3714 276.3 3.7e-73
XP_016861703 (OMIM: 600066) PREDICTED: ephrin type ( 783) 3715 276.6 4.1e-73
XP_016861702 (OMIM: 600066) PREDICTED: ephrin type ( 990) 3715 276.8 4.6e-73
XP_016861701 (OMIM: 600066) PREDICTED: ephrin type (1012) 3715 276.8 4.7e-73
XP_016861700 (OMIM: 600066) PREDICTED: ephrin type (1018) 3715 276.8 4.7e-73
XP_016861709 (OMIM: 600066) PREDICTED: ephrin type ( 522) 3366 251.9 7.5e-66
XP_016861710 (OMIM: 600066) PREDICTED: ephrin type ( 496) 3351 250.8 1.5e-65
XP_016861711 (OMIM: 600066) PREDICTED: ephrin type ( 496) 3351 250.8 1.5e-65
XP_005264773 (OMIM: 179611) PREDICTED: ephrin type ( 918) 3076 232.0 1.3e-59
NP_005224 (OMIM: 179611) ephrin type-A receptor 3 ( 983) 3076 232.1 1.3e-59
XP_005264772 (OMIM: 179611) PREDICTED: ephrin type ( 982) 3071 231.7 1.7e-59
NP_001268695 (OMIM: 600004) ephrin type-A receptor (1016) 2904 220.1 5.5e-56
NP_872272 (OMIM: 600004) ephrin type-A receptor 5 (1015) 2893 219.3 9.3e-56
XP_005246431 (OMIM: 602188) PREDICTED: ephrin type ( 949) 2779 211.3 2.3e-53
NP_001291465 (OMIM: 602188) ephrin type-A receptor ( 986) 2779 211.3 2.3e-53
NP_004429 (OMIM: 602188) ephrin type-A receptor 4 ( 986) 2779 211.3 2.3e-53
NP_001291466 (OMIM: 602188) ephrin type-A receptor ( 935) 2680 204.4 2.7e-51
NP_001265230 (OMIM: 600066) ephrin type-A receptor ( 379) 2609 198.7 5.5e-50
XP_011511007 (OMIM: 600066) PREDICTED: ephrin type ( 389) 2609 198.8 5.5e-50
XP_005248726 (OMIM: 602190) PREDICTED: ephrin type ( 994) 2616 199.9 6.2e-50
XP_011511009 (OMIM: 600066) PREDICTED: ephrin type ( 373) 2604 198.4 6.9e-50
XP_011511008 (OMIM: 600066) PREDICTED: ephrin type ( 373) 2604 198.4 6.9e-50
NP_065387 (OMIM: 176945) ephrin type-A receptor 8 (1005) 2614 199.8 6.9e-50
NP_872585 (OMIM: 179611) ephrin type-A receptor 3 ( 539) 2436 186.9 2.8e-46
XP_006710504 (OMIM: 600997,603688) PREDICTED: ephr ( 980) 2391 184.2 3.4e-45
NP_004433 (OMIM: 600997,603688) ephrin type-B rece ( 987) 2391 184.2 3.4e-45
XP_011539275 (OMIM: 176945) PREDICTED: ephrin type ( 930) 2390 184.1 3.4e-45
XP_011539274 (OMIM: 176945) PREDICTED: ephrin type ( 930) 2390 184.1 3.4e-45
XP_011539272 (OMIM: 176945) PREDICTED: ephrin type ( 930) 2390 184.1 3.4e-45
XP_011539271 (OMIM: 176945) PREDICTED: ephrin type ( 930) 2390 184.1 3.4e-45
NP_059145 (OMIM: 600997,603688) ephrin type-B rece ( 986) 2383 183.6 5e-45
NP_001296122 (OMIM: 600997,603688) ephrin type-B r (1055) 2383 183.7 5.1e-45
NP_004432 (OMIM: 600600) ephrin type-B receptor 1 ( 984) 2374 183.0 7.7e-45
NP_001268696 (OMIM: 600004) ephrin type-A receptor (1004) 2296 177.6 3.4e-43
NP_001268694 (OMIM: 600004) ephrin type-A receptor (1038) 2296 177.6 3.5e-43
NP_004430 (OMIM: 600004) ephrin type-A receptor 5 (1037) 2285 176.8 5.9e-43
NP_001305690 (OMIM: 600004) ephrin type-A receptor ( 969) 2255 174.7 2.4e-42
NP_004434 (OMIM: 601839) ephrin type-B receptor 3 ( 998) 2244 173.9 4.2e-42
XP_005248728 (OMIM: 602190) PREDICTED: ephrin type ( 610) 2168 168.3 1.3e-40
NP_775926 (OMIM: 600066) ephrin type-A receptor 6 ( 334) 1976 154.4 1.1e-36
XP_016861712 (OMIM: 600066) PREDICTED: ephrin type ( 397) 1976 154.5 1.2e-36
NP_001265229 (OMIM: 600066) ephrin type-A receptor ( 398) 1976 154.5 1.2e-36
NP_001006944 (OMIM: 176945) ephrin type-A receptor ( 495) 1833 144.7 1.3e-33
>>NP_001073917 (OMIM: 600066) ephrin type-A receptor 6 i (1130 aa)
initn: 7746 init1: 7746 opt: 7746 Z-score: 2955.1 bits: 558.7 E(85289): 7.3e-158
Smith-Waterman score: 7746; 100.0% identity (100.0% similar) in 1130 aa overlap (1-1130:1-1130)
10 20 30 40 50 60
pF1KE3 MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 PATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 DPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVM
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 WEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 VSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KE3 FTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
1090 1100 1110 1120 1130
>>XP_016861699 (OMIM: 600066) PREDICTED: ephrin type-A r (1104 aa)
initn: 5999 init1: 4033 opt: 4033 Z-score: 1552.4 bits: 299.1 E(85289): 9.9e-80
Smith-Waterman score: 7301; 94.9% identity (94.9% similar) in 1146 aa overlap (1-1130:1-1104)
10 20 30 40 50 60
pF1KE3 MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI
490 500 510 520 530 540
550 560 570 580
pF1KE3 GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEK----------------EHEQLTY
::::::::::::::::::::::::::::::::::::: :::::::
XP_016 GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKVYPRIAPAFWHYLRVEEHEQLTY
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 SSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 IATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPD
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 TYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHM
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 DRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHP
:::::::::::::::::::::::::::::::
XP_016 DRQRRDFLREASIMGQFDHPNIIRLEGVVTK-----------------------------
790 800 810
830 840 850 860 870 880
pF1KE3 VPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLS
.::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------------SRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLS
820 830 840 850
890 900 910 920 930 940
pF1KE3 DMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAY
860 870 880 890 900 910
950 960 970 980 990 1000
pF1KE3 RKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLML
920 930 940 950 960 970
1010 1020 1030 1040 1050 1060
pF1KE3 HCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWL
980 990 1000 1010 1020 1030
1070 1080 1090 1100 1110 1120
pF1KE3 DSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQ
1040 1050 1060 1070 1080 1090
1130
pF1KE3 EKGFHV
::::::
XP_016 EKGFHV
1100
>>XP_006713655 (OMIM: 600066) PREDICTED: ephrin type-A r (1146 aa)
initn: 4033 init1: 4033 opt: 4033 Z-score: 1552.2 bits: 299.1 E(85289): 1e-79
Smith-Waterman score: 7704; 98.6% identity (98.6% similar) in 1146 aa overlap (1-1130:1-1146)
10 20 30 40 50 60
pF1KE3 MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI
490 500 510 520 530 540
550 560 570 580
pF1KE3 GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEK----------------EHEQLTY
::::::::::::::::::::::::::::::::::::: :::::::
XP_006 GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKVYPRIAPAFWHYLRVEEHEQLTY
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 SSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 IATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPD
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 TYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHM
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 DRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHP
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 VPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLS
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 DMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAY
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 RKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLML
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 HCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWL
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 DSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQ
1090 1100 1110 1120 1130 1140
1130
pF1KE3 EKGFHV
::::::
XP_006 EKGFHV
>>XP_016861708 (OMIM: 600066) PREDICTED: ephrin type-A r (537 aa)
initn: 3753 init1: 3753 opt: 3753 Z-score: 1449.3 bits: 279.0 E(85289): 5.4e-74
Smith-Waterman score: 3753; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535)
10 20 30 40 50 60
pF1KE3 MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDGT
490 500 510 520 530
550 560 570 580 590 600
pF1KE3 GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLK
>>XP_016861705 (OMIM: 600066) PREDICTED: ephrin type-A r (578 aa)
initn: 3720 init1: 3720 opt: 3720 Z-score: 1436.6 bits: 276.7 E(85289): 2.8e-73
Smith-Waterman score: 3720; 100.0% identity (100.0% similar) in 554 aa overlap (577-1130:25-578)
550 560 570 580 590 600
pF1KE3 WASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKYV
::::::::::::::::::::::::::::::
XP_016 MLSQWRIQGRVELPSLRKAETRKAKEHEQLTYSSTRSKAPSVIITGLKPATKYV
10 20 30 40 50
610 620 630 640 650 660
pF1KE3 FHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLIT
60 70 80 90 100 110
670 680 690 700 710 720
pF1KE3 GRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIR
120 130 140 150 160 170
730 740 750 760 770 780
pF1KE3 IERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNI
180 190 200 210 220 230
790 800 810 820 830 840
pF1KE3 IRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVE
240 250 260 270 280 290
850 860 870 880 890 900
pF1KE3 YMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVC
300 310 320 330 340 350
910 920 930 940 950 960
pF1KE3 KVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSY
360 370 380 390 400 410
970 980 990 1000 1010 1020
pF1KE3 GERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDK
420 430 440 450 460 470
1030 1040 1050 1060 1070 1080
pF1KE3 LIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDL
480 490 500 510 520 530
1090 1100 1110 1120 1130
pF1KE3 ISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
540 550 560 570
>>XP_016861704 (OMIM: 600066) PREDICTED: ephrin type-A r (594 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1434.6 bits: 276.4 E(85289): 3.6e-73
Smith-Waterman score: 3715; 99.8% identity (100.0% similar) in 554 aa overlap (577-1130:41-594)
550 560 570 580 590 600
pF1KE3 WASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKYV
.:::::::::::::::::::::::::::::
XP_016 VELPSLRKAETRKAKVYPRIAPAFWHYLRVEEHEQLTYSSTRSKAPSVIITGLKPATKYV
20 30 40 50 60 70
610 620 630 640 650 660
pF1KE3 FHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLIT
80 90 100 110 120 130
670 680 690 700 710 720
pF1KE3 GRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIR
140 150 160 170 180 190
730 740 750 760 770 780
pF1KE3 IERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNI
200 210 220 230 240 250
790 800 810 820 830 840
pF1KE3 IRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVE
260 270 280 290 300 310
850 860 870 880 890 900
pF1KE3 YMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVC
320 330 340 350 360 370
910 920 930 940 950 960
pF1KE3 KVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSY
380 390 400 410 420 430
970 980 990 1000 1010 1020
pF1KE3 GERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDK
440 450 460 470 480 490
1030 1040 1050 1060 1070 1080
pF1KE3 LIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDL
500 510 520 530 540 550
1090 1100 1110 1120 1130
pF1KE3 ISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
560 570 580 590
>>XP_016861707 (OMIM: 600066) PREDICTED: ephrin type-A r (554 aa)
initn: 3714 init1: 3714 opt: 3714 Z-score: 1434.5 bits: 276.3 E(85289): 3.7e-73
Smith-Waterman score: 3714; 100.0% identity (100.0% similar) in 553 aa overlap (578-1130:2-554)
550 560 570 580 590 600
pF1KE3 ASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKYVF
::::::::::::::::::::::::::::::
XP_016 MEHEQLTYSSTRSKAPSVIITGLKPATKYVF
10 20 30
610 620 630 640 650 660
pF1KE3 HIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITG
40 50 60 70 80 90
670 680 690 700 710 720
pF1KE3 RCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRI
100 110 120 130 140 150
730 740 750 760 770 780
pF1KE3 ERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNII
160 170 180 190 200 210
790 800 810 820 830 840
pF1KE3 RLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEY
220 230 240 250 260 270
850 860 870 880 890 900
pF1KE3 MENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCK
280 290 300 310 320 330
910 920 930 940 950 960
pF1KE3 VSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYG
340 350 360 370 380 390
970 980 990 1000 1010 1020
pF1KE3 ERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKL
400 410 420 430 440 450
1030 1040 1050 1060 1070 1080
pF1KE3 IRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLI
460 470 480 490 500 510
1090 1100 1110 1120 1130
pF1KE3 SRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
:::::::::::::::::::::::::::::::::::::::::::
XP_016 SRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
520 530 540 550
>>XP_016861706 (OMIM: 600066) PREDICTED: ephrin type-A r (554 aa)
initn: 3714 init1: 3714 opt: 3714 Z-score: 1434.5 bits: 276.3 E(85289): 3.7e-73
Smith-Waterman score: 3714; 100.0% identity (100.0% similar) in 553 aa overlap (578-1130:2-554)
550 560 570 580 590 600
pF1KE3 ASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKYVF
::::::::::::::::::::::::::::::
XP_016 MEHEQLTYSSTRSKAPSVIITGLKPATKYVF
10 20 30
610 620 630 640 650 660
pF1KE3 HIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITG
40 50 60 70 80 90
670 680 690 700 710 720
pF1KE3 RCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRI
100 110 120 130 140 150
730 740 750 760 770 780
pF1KE3 ERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNII
160 170 180 190 200 210
790 800 810 820 830 840
pF1KE3 RLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEY
220 230 240 250 260 270
850 860 870 880 890 900
pF1KE3 MENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCK
280 290 300 310 320 330
910 920 930 940 950 960
pF1KE3 VSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYG
340 350 360 370 380 390
970 980 990 1000 1010 1020
pF1KE3 ERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKL
400 410 420 430 440 450
1030 1040 1050 1060 1070 1080
pF1KE3 IRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLI
460 470 480 490 500 510
1090 1100 1110 1120 1130
pF1KE3 SRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
:::::::::::::::::::::::::::::::::::::::::::
XP_016 SRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
520 530 540 550
>>XP_016861703 (OMIM: 600066) PREDICTED: ephrin type-A r (783 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1433.5 bits: 276.6 E(85289): 4.1e-73
Smith-Waterman score: 5100; 97.9% identity (97.9% similar) in 775 aa overlap (372-1130:9-783)
350 360 370 380 390 400
pF1KE3 LYCGADGDWLVPLGRCICSTGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEAT
::::::::::::::::::::::::::::::
XP_016 MENISIKWACRPGFYKAFAGNTKCSKCPPHSLTYMEAT
10 20 30
410 420 430 440 450 460
pF1KE3 SVCQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVCQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSV
40 50 60 70 80 90
470 480 490 500 510 520
pF1KE3 ICKKCGLDTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICKKCGLDTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFS
100 110 120 130 140 150
530 540 550 560 570
pF1KE3 PKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEK----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKVYPR
160 170 180 190 200 210
580 590 600 610 620
pF1KE3 ------------EHEQLTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFE
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAPAFWHYLRVEEHEQLTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFE
220 230 240 250 260 270
630 640 650 660 670 680
pF1KE3 FETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRN
280 290 300 310 320 330
690 700 710 720 730 740
pF1KE3 HLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLK
340 350 360 370 380 390
750 760 770 780 790 800
pF1KE3 TPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEA
400 410 420 430 440 450
810 820 830 840 850 860
pF1KE3 FCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFT
460 470 480 490 500 510
870 880 890 900 910 920
pF1KE3 VIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAY
520 530 540 550 560 570
930 940 950 960 970 980
pF1KE3 TTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEE
580 590 600 610 620 630
990 1000 1010 1020 1030 1040
pF1KE3 GYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMP
640 650 660 670 680 690
1050 1060 1070 1080 1090 1100
pF1KE3 ESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGH
700 710 720 730 740 750
1110 1120 1130
pF1KE3 QRRIVSSIQTLRLHMMHIQEKGFHV
:::::::::::::::::::::::::
XP_016 QRRIVSSIQTLRLHMMHIQEKGFHV
760 770 780
>>XP_016861702 (OMIM: 600066) PREDICTED: ephrin type-A r (990 aa)
initn: 3715 init1: 3715 opt: 3715 Z-score: 1432.6 bits: 276.8 E(85289): 4.6e-73
Smith-Waterman score: 6597; 98.4% identity (98.4% similar) in 990 aa overlap (157-1130:1-990)
130 140 150 160 170 180
pF1KE3 NQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWI
::::::::::::::::::::::::::::::
XP_016 MDEHNRPIHTYQVCNVMEPNQNNWLRTNWI
10 20 30
190 200 210 220 230 240
pF1KE3 SRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTIA
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE3 ADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVR
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE3 NLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEEI
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE3 EGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRPP
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE3 SAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPRH
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE3 TGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRKD
340 350 360 370 380 390
550 560 570 580 590
pF1KE3 WASQNSIALSWQAPAFSNGAILDYEIKYYEK----------------EHEQLTYSSTRSK
::::::::::::::::::::::::::::::: :::::::::::::
XP_016 WASQNSIALSWQAPAFSNGAILDYEIKYYEKVYPRIAPAFWHYLRVEEHEQLTYSSTRSK
400 410 420 430 440 450
600 610 620 630 640 650
pF1KE3 APSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAV
460 470 480 490 500 510
660 670 680 690 700 710
pF1KE3 GGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPS
520 530 540 550 560 570
720 730 740 750 760 770
pF1KE3 LAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRD
580 590 600 610 620 630
780 790 800 810 820 830
pF1KE3 FLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGS
640 650 660 670 680 690
840 850 860 870 880 890
pF1KE3 LPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVH
700 710 720 730 740 750
900 910 920 930 940 950
pF1KE3 RDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSA
760 770 780 790 800 810
960 970 980 990 1000 1010
pF1KE3 SDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKE
820 830 840 850 860 870
1020 1030 1040 1050 1060 1070
pF1KE3 RNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMG
880 890 900 910 920 930
1080 1090 1100 1110 1120 1130
pF1KE3 QYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
940 950 960 970 980 990
1130 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:19:39 2016 done: Mon Nov 7 20:19:41 2016
Total Scan time: 16.650 Total Display time: 0.370
Function used was FASTA [36.3.4 Apr, 2011]