Result of FASTA (omim) for
pF1KE3543
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3543, 1216 aa
1>>>pF1KE3543 1216 - 1216 aa - 1216 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.6345+/-0.000491; mu= -36.9937+/- 0.031
mean_var=748.3530+/-156.582, 0's: 0 Z-trim(123.9): 117 B-trim: 0 in 0/61
Lambda= 0.046884
statistics sampled from 44379 (44505) to 44379 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.522), width: 16
Scan time: 13.680
The best scores are: opt bits E(85289)
NP_055633 (OMIM: 612000) tripartite motif-containi (1216) 8423 586.0 4.9e-166
XP_011518812 (OMIM: 612000) PREDICTED: tripartite (1364) 7493 523.1 4.7e-147
XP_011518811 (OMIM: 612000) PREDICTED: tripartite (1367) 6455 452.9 6.4e-126
XP_011518827 (OMIM: 612000) PREDICTED: tripartite (1020) 5527 390.1 3.9e-107
XP_011518826 (OMIM: 612000) PREDICTED: tripartite (1032) 5527 390.1 4e-107
XP_011518818 (OMIM: 612000) PREDICTED: tripartite (1247) 5527 390.1 4.6e-107
XP_011518824 (OMIM: 612000) PREDICTED: tripartite (1247) 5527 390.1 4.6e-107
XP_011518821 (OMIM: 612000) PREDICTED: tripartite (1247) 5527 390.1 4.6e-107
XP_016874120 (OMIM: 612000) PREDICTED: tripartite (1247) 5527 390.1 4.6e-107
XP_011518817 (OMIM: 612000) PREDICTED: tripartite (1247) 5527 390.1 4.6e-107
XP_011518820 (OMIM: 612000) PREDICTED: tripartite (1247) 5527 390.1 4.6e-107
XP_006718461 (OMIM: 612000) PREDICTED: tripartite (1247) 5527 390.1 4.6e-107
XP_011518825 (OMIM: 612000) PREDICTED: tripartite (1247) 5527 390.1 4.6e-107
XP_011518819 (OMIM: 612000) PREDICTED: tripartite (1247) 5527 390.1 4.6e-107
XP_011518815 (OMIM: 612000) PREDICTED: tripartite (1306) 5527 390.2 4.8e-107
XP_011518816 (OMIM: 612000) PREDICTED: tripartite (1306) 5527 390.2 4.8e-107
XP_011518814 (OMIM: 612000) PREDICTED: tripartite (1306) 5527 390.2 4.8e-107
XP_016874119 (OMIM: 612000) PREDICTED: tripartite (1306) 5527 390.2 4.8e-107
XP_011518813 (OMIM: 612000) PREDICTED: tripartite (1355) 5527 390.2 5e-107
XP_011518810 (OMIM: 612000) PREDICTED: tripartite (1385) 5527 390.2 5.1e-107
XP_011518806 (OMIM: 612000) PREDICTED: tripartite (1392) 5527 390.2 5.1e-107
XP_011518809 (OMIM: 612000) PREDICTED: tripartite (1392) 5527 390.2 5.1e-107
XP_006718460 (OMIM: 612000) PREDICTED: tripartite (1392) 5527 390.2 5.1e-107
XP_016874118 (OMIM: 612000) PREDICTED: tripartite (1392) 5527 390.2 5.1e-107
XP_011518828 (OMIM: 612000) PREDICTED: tripartite (1001) 3704 266.8 5.1e-70
XP_011518829 (OMIM: 612000) PREDICTED: tripartite ( 743) 3074 224.1 2.7e-57
XP_016856942 (OMIM: 188550,605769) PREDICTED: E3 u ( 718) 844 73.3 6.6e-12
NP_148980 (OMIM: 188550,605769) E3 ubiquitin-prote (1110) 812 71.2 4.3e-11
NP_056990 (OMIM: 188550,605769) E3 ubiquitin-prote (1127) 812 71.2 4.3e-11
XP_016856943 (OMIM: 188550,605769) PREDICTED: E3 u ( 638) 799 70.2 5e-11
XP_005270994 (OMIM: 188550,605769) PREDICTED: E3 u (1134) 807 70.9 5.5e-11
XP_011539870 (OMIM: 188550,605769) PREDICTED: E3 u (1150) 807 70.9 5.5e-11
XP_005270993 (OMIM: 188550,605769) PREDICTED: E3 u (1151) 807 70.9 5.5e-11
NP_056989 (OMIM: 188550,603406) transcription inte (1050) 768 68.2 3.2e-10
NP_003843 (OMIM: 188550,603406) transcription inte (1016) 762 67.8 4.1e-10
XP_016856941 (OMIM: 188550,605769) PREDICTED: E3 u ( 735) 746 66.6 6.7e-10
NP_005753 (OMIM: 601742) transcription intermediar ( 835) 578 55.3 2e-06
>>NP_055633 (OMIM: 612000) tripartite motif-containing p (1216 aa)
initn: 8423 init1: 8423 opt: 8423 Z-score: 3101.8 bits: 586.0 E(85289): 4.9e-166
Smith-Waterman score: 8423; 100.0% identity (100.0% similar) in 1216 aa overlap (1-1216:1-1216)
10 20 30 40 50 60
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 LCPRDGADPSLENALCKVKLEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LCPRDGADPSLENALCKVKLEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGAL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 ELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIECG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIECG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 TESSSMSIKVSQDRLSEATQAPGLEGRKVTVTSLAGQRPPEVEGTSPEEHRLIPRTPGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TESSSMSIKVSQDRLSEATQAPGLEGRKVTVTSLAGQRPPEVEGTSPEEHRLIPRTPGAK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 KGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 EMEYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EMEYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 IKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFF
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 EGWLKEIYPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGWLKEIYPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMENE
1150 1160 1170 1180 1190 1200
1210
pF1KE3 RAKRMSFRLANSISQV
::::::::::::::::
NP_055 RAKRMSFRLANSISQV
1210
>>XP_011518812 (OMIM: 612000) PREDICTED: tripartite moti (1364 aa)
initn: 7528 init1: 5520 opt: 7493 Z-score: 2761.1 bits: 523.1 E(85289): 4.7e-147
Smith-Waterman score: 8106; 95.1% identity (95.3% similar) in 1247 aa overlap (1-1216:146-1364)
10 20 30
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCT
::::::::::::::::::::::::::::::
XP_011 ISCPGCERVYLTRDVTEHFFLHCVPTEQPKMARNCSECKEKRAAHILCTYCNRWLCSSCT
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE3 EEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLV
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE3 VEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQ
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE3 IKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVC
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE3 SKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGG
360 370 380 390 400 410
280 290 300 310 320 330
pF1KE3 QMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSP
420 430 440 450 460 470
340 350 360 370 380 390
pF1KE3 SLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQ
480 490 500 510 520 530
400 410 420 430 440 450
pF1KE3 PPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQ
540 550 560 570 580 590
460 470 480 490 500 510
pF1KE3 QQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHH
600 610 620 630 640 650
520 530 540 550 560 570
pF1KE3 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL
660 670 680 690 700 710
580 590 600 610 620 630
pF1KE3 QATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSL
720 730 740 750 760 770
640 650 660 670 680 690
pF1KE3 SIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQ
780 790 800 810 820 830
700 710 720 730 740 750
pF1KE3 AMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSL
840 850 860 870 880 890
760 770 780 790
pF1KE3 ATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKVK-----------
:::::::::::::::::::::::::::::::::::::::::::::::..
XP_011 ATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKMESEDSTRFTDLL
900 910 920 930 940 950
800 810 820 830
pF1KE3 --------------------LEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGA
::::::::::::::::::::::::::::::::::::::::
XP_011 GQGPIVPGLDAPKDLAIPSELEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGA
960 970 980 990 1000 1010
840 850 860 870 880 890
pF1KE3 LELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIEC
1020 1030 1040 1050 1060 1070
900 910 920 930 940 950
pF1KE3 GTESSSMSIKVSQDRLSEATQAPGLEGRKVTVTSLAGQRPPEVEGTSPEEHRLIPRTPGA
:::::::::: ::::::::::::::::::::::
XP_011 GTESSSMSIK----------------------------RPPEVEGTSPEEHRLIPRTPGA
1080 1090 1100
960 970 980 990 1000 1010
pF1KE3 KKGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQ
1110 1120 1130 1140 1150 1160
1020 1030 1040 1050 1060 1070
pF1KE3 PEMEYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEMEYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQ
1170 1180 1190 1200 1210 1220
1080 1090 1100 1110 1120 1130
pF1KE3 IIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVF
1230 1240 1250 1260 1270 1280
1140 1150 1160 1170 1180 1190
pF1KE3 FEGWLKEIYPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEGWLKEIYPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMEN
1290 1300 1310 1320 1330 1340
1200 1210
pF1KE3 ERAKRMSFRLANSISQV
:::::::::::::::::
XP_011 ERAKRMSFRLANSISQV
1350 1360
>>XP_011518811 (OMIM: 612000) PREDICTED: tripartite moti (1367 aa)
initn: 6505 init1: 5520 opt: 6455 Z-score: 2381.7 bits: 452.9 E(85289): 6.4e-126
Smith-Waterman score: 8102; 95.3% identity (95.5% similar) in 1247 aa overlap (1-1216:146-1367)
10 20 30
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCT
::::::::::::::::::::::::::::::
XP_011 ISCPGCERVYLTRDVTEHFFLHCVPTEQPKMARNCSECKEKRAAHILCTYCNRWLCSSCT
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE3 EEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLV
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE3 VEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQ
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE3 IKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVC
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE3 SKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGG
360 370 380 390 400 410
280 290 300 310 320 330
pF1KE3 QMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSP
420 430 440 450 460 470
340 350 360 370 380 390
pF1KE3 SLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQ
480 490 500 510 520 530
400 410 420 430 440 450
pF1KE3 PPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQ
540 550 560 570 580 590
460 470 480 490 500 510
pF1KE3 QQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHH
600 610 620 630 640 650
520 530 540 550 560 570
pF1KE3 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL
660 670 680 690 700 710
580 590 600 610 620 630
pF1KE3 QATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSL
720 730 740 750 760 770
640 650 660 670 680 690
pF1KE3 SIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQ
780 790 800 810 820 830
700 710 720 730 740 750
pF1KE3 AMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSL
840 850 860 870 880 890
760 770 780 790
pF1KE3 ATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKVK-----------
:::::::::::::::::::::::::::::::::::::::::::::::..
XP_011 ATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKMESEDSTRFTDLL
900 910 920 930 940 950
800 810 820 830
pF1KE3 --------------------LEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGA
::::::::::::::::::::::::::::::::::::::::
XP_011 GQGPIVPGLDAPKDLAIPSELEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGA
960 970 980 990 1000 1010
840 850 860 870 880 890
pF1KE3 LELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIEC
1020 1030 1040 1050 1060 1070
900 910 920 930 940 950
pF1KE3 GTESSSMSIKVSQDRLSEATQAPGLEGRKVTVTSLAGQRPPEVEGTSPEEHRLIPRTPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTESSSMSIKVSQDRLSEATQAPGLEGRKVTVTSLAGQRPPEVEGTSPEEHRLIPRTPGA
1080 1090 1100 1110 1120 1130
960 970 980 990 1000 1010
pF1KE3 KKGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQ
1140 1150 1160 1170 1180 1190
1020 1030 1040 1050 1060 1070
pF1KE3 PEMEYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQ
::::::::::::::::::::::::::::: ::::::
XP_011 PEMEYDCENACYNQPGMRASPGLSMYDQK-------------------------ARHYYQ
1200 1210 1220 1230
1080 1090 1100 1110 1120 1130
pF1KE3 IIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVF
1240 1250 1260 1270 1280 1290
1140 1150 1160 1170 1180 1190
pF1KE3 FEGWLKEIYPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEGWLKEIYPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMEN
1300 1310 1320 1330 1340 1350
1200 1210
pF1KE3 ERAKRMSFRLANSISQV
:::::::::::::::::
XP_011 ERAKRMSFRLANSISQV
1360
>>XP_011518827 (OMIM: 612000) PREDICTED: tripartite moti (1020 aa)
initn: 6040 init1: 5520 opt: 5527 Z-score: 2044.3 bits: 390.1 E(85289): 3.9e-107
Smith-Waterman score: 5641; 96.2% identity (96.4% similar) in 861 aa overlap (1-830:146-1006)
10 20 30
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCT
::::::::::::::::::::::::::::::
XP_011 ISCPGCERVYLTRDVTEHFFLHCVPTEQPKMARNCSECKEKRAAHILCTYCNRWLCSSCT
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE3 EEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLV
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE3 VEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQ
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE3 IKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVC
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE3 SKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGG
360 370 380 390 400 410
280 290 300 310 320 330
pF1KE3 QMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSP
420 430 440 450 460 470
340 350 360 370 380 390
pF1KE3 SLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQ
480 490 500 510 520 530
400 410 420 430 440 450
pF1KE3 PPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQ
540 550 560 570 580 590
460 470 480 490 500 510
pF1KE3 QQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHH
600 610 620 630 640 650
520 530 540 550 560 570
pF1KE3 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL
660 670 680 690 700 710
580 590 600 610 620 630
pF1KE3 QATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSL
720 730 740 750 760 770
640 650 660 670 680 690
pF1KE3 SIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQ
780 790 800 810 820 830
700 710 720 730 740 750
pF1KE3 AMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSL
840 850 860 870 880 890
760 770 780 790
pF1KE3 ATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKVK-----------
:::::::::::::::::::::::::::::::::::::::::::::::..
XP_011 ATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKMESEDSTRFTDLL
900 910 920 930 940 950
800 810 820 830
pF1KE3 --------------------LEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGA
:::::::::::::::::::::::::::::::
XP_011 GQGPIVPGLDAPKDLAIPSELEEPINLSVKKPPLAPVVSTSTALQQYQNPKGETQAACPS
960 970 980 990 1000 1010
840 850 860 870 880 890
pF1KE3 LELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIEC
XP_011 CWPQT
1020
>>XP_011518826 (OMIM: 612000) PREDICTED: tripartite moti (1032 aa)
initn: 6178 init1: 5520 opt: 5527 Z-score: 2044.3 bits: 390.1 E(85289): 4e-107
Smith-Waterman score: 5779; 96.3% identity (96.5% similar) in 882 aa overlap (1-851:146-1027)
10 20 30
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCT
::::::::::::::::::::::::::::::
XP_011 ISCPGCERVYLTRDVTEHFFLHCVPTEQPKMARNCSECKEKRAAHILCTYCNRWLCSSCT
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE3 EEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLV
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE3 VEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQ
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE3 IKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVC
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE3 SKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGG
360 370 380 390 400 410
280 290 300 310 320 330
pF1KE3 QMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSP
420 430 440 450 460 470
340 350 360 370 380 390
pF1KE3 SLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQ
480 490 500 510 520 530
400 410 420 430 440 450
pF1KE3 PPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQ
540 550 560 570 580 590
460 470 480 490 500 510
pF1KE3 QQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHH
600 610 620 630 640 650
520 530 540 550 560 570
pF1KE3 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL
660 670 680 690 700 710
580 590 600 610 620 630
pF1KE3 QATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSL
720 730 740 750 760 770
640 650 660 670 680 690
pF1KE3 SIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQ
780 790 800 810 820 830
700 710 720 730 740 750
pF1KE3 AMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSL
840 850 860 870 880 890
760 770 780 790
pF1KE3 ATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKVK-----------
:::::::::::::::::::::::::::::::::::::::::::::::..
XP_011 ATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKMESEDSTRFTDLL
900 910 920 930 940 950
800 810 820 830
pF1KE3 --------------------LEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGA
::::::::::::::::::::::::::::::::::::::::
XP_011 GQGPIVPGLDAPKDLAIPSELEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGA
960 970 980 990 1000 1010
840 850 860 870 880 890
pF1KE3 LELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIEC
::::::::::::
XP_011 LELDAKENQSIRDHGCF
1020 1030
>>XP_011518818 (OMIM: 612000) PREDICTED: tripartite moti (1247 aa)
initn: 5520 init1: 5520 opt: 5527 Z-score: 2043.0 bits: 390.1 E(85289): 4.6e-107
Smith-Waterman score: 8342; 97.4% identity (97.5% similar) in 1247 aa overlap (1-1216:1-1247)
10 20 30 40 50 60
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
730 740 750 760 770 780
790 800
pF1KE3 LCPRDGADPSLENALCKVK-------------------------------LEEPINLSVK
:::::::::::::::::.. ::::::::::
XP_011 LCPRDGADPSLENALCKMESEDSTRFTDLLGQGPIVPGLDAPKDLAIPSELEEPINLSVK
790 800 810 820 830 840
810 820 830 840 850 860
pF1KE3 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE3 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE3 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE3 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE3 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE3 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210
pF1KE3 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
1210 1220 1230 1240
>>XP_011518824 (OMIM: 612000) PREDICTED: tripartite moti (1247 aa)
initn: 5520 init1: 5520 opt: 5527 Z-score: 2043.0 bits: 390.1 E(85289): 4.6e-107
Smith-Waterman score: 8342; 97.4% identity (97.5% similar) in 1247 aa overlap (1-1216:1-1247)
10 20 30 40 50 60
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
730 740 750 760 770 780
790 800
pF1KE3 LCPRDGADPSLENALCKVK-------------------------------LEEPINLSVK
:::::::::::::::::.. ::::::::::
XP_011 LCPRDGADPSLENALCKMESEDSTRFTDLLGQGPIVPGLDAPKDLAIPSELEEPINLSVK
790 800 810 820 830 840
810 820 830 840 850 860
pF1KE3 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE3 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE3 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE3 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE3 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE3 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210
pF1KE3 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
1210 1220 1230 1240
>>XP_011518821 (OMIM: 612000) PREDICTED: tripartite moti (1247 aa)
initn: 5520 init1: 5520 opt: 5527 Z-score: 2043.0 bits: 390.1 E(85289): 4.6e-107
Smith-Waterman score: 8342; 97.4% identity (97.5% similar) in 1247 aa overlap (1-1216:1-1247)
10 20 30 40 50 60
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
730 740 750 760 770 780
790 800
pF1KE3 LCPRDGADPSLENALCKVK-------------------------------LEEPINLSVK
:::::::::::::::::.. ::::::::::
XP_011 LCPRDGADPSLENALCKMESEDSTRFTDLLGQGPIVPGLDAPKDLAIPSELEEPINLSVK
790 800 810 820 830 840
810 820 830 840 850 860
pF1KE3 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE3 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE3 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE3 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE3 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE3 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210
pF1KE3 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
1210 1220 1230 1240
>>XP_016874120 (OMIM: 612000) PREDICTED: tripartite moti (1247 aa)
initn: 5520 init1: 5520 opt: 5527 Z-score: 2043.0 bits: 390.1 E(85289): 4.6e-107
Smith-Waterman score: 8342; 97.4% identity (97.5% similar) in 1247 aa overlap (1-1216:1-1247)
10 20 30 40 50 60
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
730 740 750 760 770 780
790 800
pF1KE3 LCPRDGADPSLENALCKVK-------------------------------LEEPINLSVK
:::::::::::::::::.. ::::::::::
XP_016 LCPRDGADPSLENALCKMESEDSTRFTDLLGQGPIVPGLDAPKDLAIPSELEEPINLSVK
790 800 810 820 830 840
810 820 830 840 850 860
pF1KE3 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE3 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE3 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE3 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE3 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE3 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210
pF1KE3 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
1210 1220 1230 1240
>>XP_011518817 (OMIM: 612000) PREDICTED: tripartite moti (1247 aa)
initn: 5520 init1: 5520 opt: 5527 Z-score: 2043.0 bits: 390.1 E(85289): 4.6e-107
Smith-Waterman score: 8342; 97.4% identity (97.5% similar) in 1247 aa overlap (1-1216:1-1247)
10 20 30 40 50 60
pF1KE3 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGS
730 740 750 760 770 780
790 800
pF1KE3 LCPRDGADPSLENALCKVK-------------------------------LEEPINLSVK
:::::::::::::::::.. ::::::::::
XP_011 LCPRDGADPSLENALCKMESEDSTRFTDLLGQGPIVPGLDAPKDLAIPSELEEPINLSVK
790 800 810 820 830 840
810 820 830 840 850 860
pF1KE3 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKI
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE3 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE3 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCP
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE3 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE3 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVV
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE3 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSE
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210
pF1KE3 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
1210 1220 1230 1240
1216 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:26:08 2016 done: Tue Nov 8 17:26:10 2016
Total Scan time: 13.680 Total Display time: 0.370
Function used was FASTA [36.3.4 Apr, 2011]