FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3561, 926 aa 1>>>pF1KE3561 926 - 926 aa - 926 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5396+/-0.0006; mu= 20.4807+/- 0.037 mean_var=88.7932+/-17.598, 0's: 0 Z-trim(106.9): 125 B-trim: 0 in 0/51 Lambda= 0.136108 statistics sampled from 14877 (15009) to 14877 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.489), E-opt: 0.2 (0.176), width: 16 Scan time: 7.600 The best scores are: opt bits E(85289) NP_683766 (OMIM: 613572) G-protein coupled recepto ( 926) 6163 1221.8 0 XP_016865964 (OMIM: 613572) PREDICTED: G-protein c ( 879) 5852 1160.7 0 XP_016865965 (OMIM: 613572) PREDICTED: G-protein c ( 558) 3728 743.5 6.9e-214 NP_001273283 (OMIM: 613572) G-protein coupled rece ( 751) 3233 646.4 1.6e-184 NP_001273284 (OMIM: 613572) G-protein coupled rece ( 855) 2932 587.3 1.1e-166 XP_005247894 (OMIM: 145980,239200,601198,601199,61 ( 917) 1023 212.5 7.9e-54 NP_000379 (OMIM: 145980,239200,601198,601199,61289 (1078) 737 156.4 7.2e-37 XP_016862813 (OMIM: 145980,239200,601198,601199,61 (1078) 737 156.4 7.2e-37 XP_006713852 (OMIM: 145980,239200,601198,601199,61 (1078) 737 156.4 7.2e-37 XP_016862814 (OMIM: 145980,239200,601198,601199,61 (1078) 737 156.4 7.2e-37 NP_001171536 (OMIM: 145980,239200,601198,601199,61 (1088) 737 156.4 7.3e-37 NP_803884 (OMIM: 606225) taste receptor type 1 mem ( 587) 727 154.2 1.8e-36 XP_016857892 (OMIM: 606225) PREDICTED: taste recep ( 589) 727 154.2 1.8e-36 NP_689414 (OMIM: 605865) taste receptor type 1 mem ( 852) 721 153.1 5.3e-36 XP_016857925 (OMIM: 605865) PREDICTED: taste recep ( 893) 721 153.2 5.5e-36 XP_016857924 (OMIM: 605865) PREDICTED: taste recep ( 894) 721 153.2 5.5e-36 NP_619642 (OMIM: 606225) taste receptor type 1 mem ( 841) 632 135.7 9.6e-31 NP_689418 (OMIM: 606226) taste receptor type 1 mem ( 839) 594 128.2 1.7e-28 XP_016866277 (OMIM: 604473,614831) PREDICTED: meta ( 785) 587 126.8 4.2e-28 XP_011531948 (OMIM: 604099) PREDICTED: metabotropi ( 494) 579 125.1 8.8e-28 XP_011531942 (OMIM: 604099) PREDICTED: metabotropi ( 678) 580 125.4 9.7e-28 XP_011531943 (OMIM: 604099) PREDICTED: metabotropi ( 678) 580 125.4 9.7e-28 XP_011531939 (OMIM: 604099) PREDICTED: metabotropi ( 678) 580 125.4 9.7e-28 XP_011531941 (OMIM: 604099) PREDICTED: metabotropi ( 678) 580 125.4 9.7e-28 XP_011531940 (OMIM: 604099) PREDICTED: metabotropi ( 678) 580 125.4 9.7e-28 XP_011531938 (OMIM: 604099) PREDICTED: metabotropi ( 690) 580 125.4 9.8e-28 XP_011540508 (OMIM: 606225) PREDICTED: taste recep ( 580) 575 124.3 1.7e-27 XP_016857891 (OMIM: 606225) PREDICTED: taste recep ( 843) 575 124.5 2.3e-27 NP_000835 (OMIM: 604101) metabotropic glutamate re ( 915) 574 124.3 2.8e-27 NP_870989 (OMIM: 604101) metabotropic glutamate re ( 922) 573 124.1 3.2e-27 XP_011540505 (OMIM: 606225) PREDICTED: taste recep ( 763) 570 123.5 4.1e-27 NP_000831 (OMIM: 601115) metabotropic glutamate re ( 879) 547 119.0 1.1e-25 XP_011531947 (OMIM: 604099) PREDICTED: metabotropi ( 403) 539 117.1 1.7e-25 XP_011531946 (OMIM: 604099) PREDICTED: metabotropi ( 403) 539 117.1 1.7e-25 XP_011531945 (OMIM: 604099) PREDICTED: metabotropi ( 440) 539 117.2 1.9e-25 XP_011531949 (OMIM: 604099) PREDICTED: metabotropi ( 459) 539 117.2 1.9e-25 XP_016867562 (OMIM: 601115) PREDICTED: metabotropi ( 479) 529 115.2 7.7e-25 XP_011514390 (OMIM: 601115) PREDICTED: metabotropi ( 537) 529 115.3 8.4e-25 XP_011531944 (OMIM: 604099) PREDICTED: metabotropi ( 470) 506 110.7 1.7e-23 XP_011531937 (OMIM: 604099) PREDICTED: metabotropi ( 840) 506 110.9 2.7e-23 NP_000830 (OMIM: 604099) metabotropic glutamate re ( 872) 506 110.9 2.8e-23 XP_016861760 (OMIM: 604099) PREDICTED: metabotropi ( 872) 506 110.9 2.8e-23 NP_000833 (OMIM: 604102) metabotropic glutamate re (1180) 493 108.5 2e-22 XP_016873116 (OMIM: 604102) PREDICTED: metabotropi (1180) 493 108.5 2e-22 NP_001137303 (OMIM: 604102) metabotropic glutamate (1212) 493 108.5 2.1e-22 XP_006718891 (OMIM: 604102) PREDICTED: metabotropi (1212) 493 108.5 2.1e-22 XP_011541094 (OMIM: 604102) PREDICTED: metabotropi (1212) 493 108.5 2.1e-22 XP_016867563 (OMIM: 601116) PREDICTED: metabotropi ( 908) 487 107.2 3.8e-22 XP_011514393 (OMIM: 601116) PREDICTED: metabotropi ( 908) 487 107.2 3.8e-22 XP_006716001 (OMIM: 601116) PREDICTED: metabotropi ( 908) 487 107.2 3.8e-22 >>NP_683766 (OMIM: 613572) G-protein coupled receptor fa (926 aa) initn: 6163 init1: 6163 opt: 6163 Z-score: 6542.0 bits: 1221.8 E(85289): 0 Smith-Waterman score: 6163; 99.9% identity (99.9% similar) in 926 aa overlap (1-926:1-926) 10 20 30 40 50 60 pF1KE3 MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 QECVGFEISVFLQTLAMIHSIEMINNSTLLSGVKLGYEIYDTCTEVTVAMAATLRFLSKF :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: NP_683 QECVGFEISVFLQTLAMIHSIEMINNSTLLPGVKLGYEIYDTCTEVTVAMAATLRFLSKF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 NCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 NCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 RFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 RFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 FKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 FKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 ASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 ASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 LSACAYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 LSACAYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 ALGYAIRDLCQARDCQNPNAFQPWELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 ALGYAIRDLCQARDCQNPNAFQPWELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE3 EINGHMTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 EINGHMTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE3 CCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 CCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE3 SLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 SLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE3 TRQTMFGVSFTLCISCILTKSLKILLAFSFDPKLQKFLKCLYRPILIIFTCTGIQVVICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 TRQTMFGVSFTLCISCILTKSLKILLAFSFDPKLQKFLKCLYRPILIIFTCTGIQVVICT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE3 LWLIFAAPTVEVNVSLPRVIILECEEGSILAFGTMLGYIAILAFICFIFAFKGKYENYNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 LWLIFAAPTVEVNVSLPRVIILECEEGSILAFGTMLGYIAILAFICFIFAFKGKYENYNE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE3 AKFITFGMLIYFIAWITFIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 AKFITFGMLIYFIAWITFIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE3 QEINTKSAFLKMIYSYSSHSVSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_683 QEINTKSAFLKMIYSYSSHSVSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQA 850 860 870 880 890 900 910 920 pF1KE3 QAFAHICRENATSVSKTLPRKRMSSI :::::::::::::::::::::::::: NP_683 QAFAHICRENATSVSKTLPRKRMSSI 910 920 >>XP_016865964 (OMIM: 613572) PREDICTED: G-protein coupl (879 aa) initn: 5852 init1: 5852 opt: 5852 Z-score: 6212.3 bits: 1160.7 E(85289): 0 Smith-Waterman score: 5852; 99.9% identity (99.9% similar) in 879 aa overlap (48-926:1-879) 20 30 40 50 60 70 pF1KE3 SQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQIQECVGFEISVFLQTLAM :::::::::::::::::::::::::::::: XP_016 MLSSEDSPRRPQIQECVGFEISVFLQTLAM 10 20 30 80 90 100 110 120 130 pF1KE3 IHSIEMINNSTLLSGVKLGYEIYDTCTEVTVAMAATLRFLSKFNCSRETVEFKCDYSSYM ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: XP_016 IHSIEMINNSTLLPGVKLGYEIYDTCTEVTVAMAATLRFLSKFNCSRETVEFKCDYSSYM 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE3 PRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKIRFPSFLRTVPSDFHQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKIRFPSFLRTVPSDFHQIK 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE3 AMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIAFKEVLPAFLSDNTIEVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIAFKEVLPAFLSDNTIEVR 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE3 INRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWIASDNWSTATKITTIPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWIASDNWSTATKITTIPNV 220 230 240 250 260 270 320 330 340 350 360 370 pF1KE3 KKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMHLSACAYVKDTDLSQCIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMHLSACAYVKDTDLSQCIF 280 290 300 310 320 330 380 390 400 410 420 430 pF1KE3 NHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVFALGYAIRDLCQARDCQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVFALGYAIRDLCQARDCQN 340 350 360 370 380 390 440 450 460 470 480 490 pF1KE3 PNAFQPWELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWKEINGHMTVTKMAEYDLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNAFQPWELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWKEINGHMTVTKMAEYDLQ 400 410 420 430 440 450 500 510 520 530 540 550 pF1KE3 NDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHICCYECQNCPENHYTNQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHICCYECQNCPENHYTNQT 460 470 480 490 500 510 560 570 580 590 600 610 pF1KE3 DMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTR 520 530 540 550 560 570 620 630 640 650 660 670 pF1KE3 NLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCI 580 590 600 610 620 630 680 690 700 710 720 730 pF1KE3 LTKSLKILLAFSFDPKLQKFLKCLYRPILIIFTCTGIQVVICTLWLIFAAPTVEVNVSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTKSLKILLAFSFDPKLQKFLKCLYRPILIIFTCTGIQVVICTLWLIFAAPTVEVNVSLP 640 650 660 670 680 690 740 750 760 770 780 790 pF1KE3 RVIILECEEGSILAFGTMLGYIAILAFICFIFAFKGKYENYNEAKFITFGMLIYFIAWIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVIILECEEGSILAFGTMLGYIAILAFICFIFAFKGKYENYNEAKFITFGMLIYFIAWIT 700 710 720 730 740 750 800 810 820 830 840 850 pF1KE3 FIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQEINTKSAFLKMIYSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQEINTKSAFLKMIYSYS 760 770 780 790 800 810 860 870 880 890 900 910 pF1KE3 SHSVSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQAQAFAHICRENATSVSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHSVSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQAQAFAHICRENATSVSKT 820 830 840 850 860 870 920 pF1KE3 LPRKRMSSI ::::::::: XP_016 LPRKRMSSI >>XP_016865965 (OMIM: 613572) PREDICTED: G-protein coupl (558 aa) initn: 3728 init1: 3728 opt: 3728 Z-score: 3960.9 bits: 743.5 E(85289): 6.9e-214 Smith-Waterman score: 3728; 99.8% identity (99.8% similar) in 557 aa overlap (1-557:1-557) 10 20 30 40 50 60 pF1KE3 MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 QECVGFEISVFLQTLAMIHSIEMINNSTLLSGVKLGYEIYDTCTEVTVAMAATLRFLSKF :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: XP_016 QECVGFEISVFLQTLAMIHSIEMINNSTLLPGVKLGYEIYDTCTEVTVAMAATLRFLSKF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 NCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 RFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 FKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 ASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 LSACAYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSACAYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 ALGYAIRDLCQARDCQNPNAFQPWELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALGYAIRDLCQARDCQNPNAFQPWELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE3 EINGHMTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EINGHMTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE3 CCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLIL ::::::::::::::::: XP_016 CCYECQNCPENHYTNQTG 550 >>NP_001273283 (OMIM: 613572) G-protein coupled receptor (751 aa) initn: 3233 init1: 3233 opt: 3233 Z-score: 3433.8 bits: 646.4 E(85289): 1.6e-184 Smith-Waterman score: 4612; 81.0% identity (81.0% similar) in 926 aa overlap (1-926:1-751) 10 20 30 40 50 60 pF1KE3 MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 QECVGFEISVFLQTLAMIHSIEMINNSTLLSGVKLGYEIYDTCTEVTVAMAATLRFLSKF :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: NP_001 QECVGFEISVFLQTLAMIHSIEMINNSTLLPGVKLGYEIYDTCTEVTVAMAATLRFLSKF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 NCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 RFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 FKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWI :::::::::::::::::::::::::::::: NP_001 FKEVLPAFLSDNTIEVRINRTLKKIILEAQ------------------------------ 250 260 270 310 320 330 340 350 360 pF1KE3 ASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMH NP_001 ------------------------------------------------------------ 370 380 390 400 410 420 pF1KE3 LSACAYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVF NP_001 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KE3 ALGYAIRDLCQARDCQNPNAFQPWELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWK ::::::::::::::::::::::::::::::::::: NP_001 -------------------------LLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWK 280 290 300 490 500 510 520 530 540 pF1KE3 EINGHMTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EINGHMTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHI 310 320 330 340 350 360 550 560 570 580 590 600 pF1KE3 CCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLIL 370 380 390 400 410 420 610 620 630 640 650 660 pF1KE3 SLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCK 430 440 450 460 470 480 670 680 690 700 710 720 pF1KE3 TRQTMFGVSFTLCISCILTKSLKILLAFSFDPKLQKFLKCLYRPILIIFTCTGIQVVICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRQTMFGVSFTLCISCILTKSLKILLAFSFDPKLQKFLKCLYRPILIIFTCTGIQVVICT 490 500 510 520 530 540 730 740 750 760 770 780 pF1KE3 LWLIFAAPTVEVNVSLPRVIILECEEGSILAFGTMLGYIAILAFICFIFAFKGKYENYNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWLIFAAPTVEVNVSLPRVIILECEEGSILAFGTMLGYIAILAFICFIFAFKGKYENYNE 550 560 570 580 590 600 790 800 810 820 830 840 pF1KE3 AKFITFGMLIYFIAWITFIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKFITFGMLIYFIAWITFIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICK 610 620 630 640 650 660 850 860 870 880 890 900 pF1KE3 QEINTKSAFLKMIYSYSSHSVSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEINTKSAFLKMIYSYSSHSVSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQA 670 680 690 700 710 720 910 920 pF1KE3 QAFAHICRENATSVSKTLPRKRMSSI :::::::::::::::::::::::::: NP_001 QAFAHICRENATSVSKTLPRKRMSSI 730 740 750 >>NP_001273284 (OMIM: 613572) G-protein coupled receptor (855 aa) initn: 2977 init1: 2932 opt: 2932 Z-score: 3113.7 bits: 587.3 E(85289): 1.1e-166 Smith-Waterman score: 5526; 92.2% identity (92.2% similar) in 926 aa overlap (1-926:1-855) 10 20 30 40 50 60 pF1KE3 MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 QECVGFEISVFLQTLAMIHSIEMINNSTLLSGVKLGYEIYDTCTEVTVAMAATLRFLSKF :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: NP_001 QECVGFEISVFLQTLAMIHSIEMINNSTLLPGVKLGYEIYDTCTEVTVAMAATLRFLSKF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 NCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 RFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 FKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 ASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 LSACAYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSACAYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 ALGYAIRDLCQARDCQNPNAFQPWELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWK ::::::::::::::::::::::::: NP_001 ALGYAIRDLCQARDCQNPNAFQPWE----------------------------------- 430 440 490 500 510 520 530 540 pF1KE3 EINGHMTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHI :::::::::::::::::::::::: NP_001 ------------------------------------QIQSKCSKECSPGQMKKTTRSQHI 450 460 550 560 570 580 590 600 pF1KE3 CCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLIL 470 480 490 500 510 520 610 620 630 640 650 660 pF1KE3 SLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCK 530 540 550 560 570 580 670 680 690 700 710 720 pF1KE3 TRQTMFGVSFTLCISCILTKSLKILLAFSFDPKLQKFLKCLYRPILIIFTCTGIQVVICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRQTMFGVSFTLCISCILTKSLKILLAFSFDPKLQKFLKCLYRPILIIFTCTGIQVVICT 590 600 610 620 630 640 730 740 750 760 770 780 pF1KE3 LWLIFAAPTVEVNVSLPRVIILECEEGSILAFGTMLGYIAILAFICFIFAFKGKYENYNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWLIFAAPTVEVNVSLPRVIILECEEGSILAFGTMLGYIAILAFICFIFAFKGKYENYNE 650 660 670 680 690 700 790 800 810 820 830 840 pF1KE3 AKFITFGMLIYFIAWITFIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKFITFGMLIYFIAWITFIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICK 710 720 730 740 750 760 850 860 870 880 890 900 pF1KE3 QEINTKSAFLKMIYSYSSHSVSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEINTKSAFLKMIYSYSSHSVSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQA 770 780 790 800 810 820 910 920 pF1KE3 QAFAHICRENATSVSKTLPRKRMSSI :::::::::::::::::::::::::: NP_001 QAFAHICRENATSVSKTLPRKRMSSI 830 840 850 >>XP_005247894 (OMIM: 145980,239200,601198,601199,612899 (917 aa) initn: 1026 init1: 295 opt: 1023 Z-score: 1087.4 bits: 212.5 E(85289): 7.9e-54 Smith-Waterman score: 1483; 32.6% identity (64.3% similar) in 807 aa overlap (164-924:1-795) 140 150 160 170 180 190 pF1KE3 SSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKIRFPSFLRTVPSDF : ::.: :....::.: .: :::::.:.: XP_005 MYQVSYASSSRLLSNKNQFKSFLRTIPNDE 10 20 30 200 210 220 230 240 250 pF1KE3 HQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIAFKEVLPAFLSDNT :: ::: .:. :::.: :..:::::: ... : .:: ..:: :.:.. . ... XP_005 HQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEE 40 50 60 70 80 90 260 270 280 290 300 310 pF1KE3 IEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNIN-KMWIASDNWSTATKIT :. . ..: .. ..::::: . :... .. ::. :.:.::. :.... :. XP_005 IQHVV-----EVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGKIWLASEAWASSSLIA 100 110 120 130 140 320 330 340 350 360 pF1KE3 TIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMHLSAC-------- . .: ..:::.. :.: .:. ::...: : . . .:. . : XP_005 MPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQEGAKG 150 160 170 180 190 200 370 380 390 400 410 pF1KE3 -----AYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAV .... . : :..: . :.. . ..:. . ::.. . ... ::: XP_005 PLPVDTFLRGHEESGDRFSNS--STAFRPLCTGDENISSVETPYIDYTHLRISYNVYLAV 210 220 230 240 250 260 420 430 440 450 460 pF1KE3 FALGYAIRDL--C-QAR------DCQNPNAFQPWELLGVLKNVTFTDGWN-SFHFDAHGD .....:..:. : .: .: . . . :..: :....::.. . . :: :: XP_005 YSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGD 270 280 290 300 310 320 470 480 490 500 510 520 pF1KE3 LNTGYDVVLWK--EINGHMTVTKMAEYDLQND----VFIIPDQETKNEFRNLKQIQ-SKC : .:... :. .: .. ... :.. .:: .. . : ... :.: XP_005 LVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFS--REVPFSNC 330 340 350 360 370 380 530 540 550 560 570 580 pF1KE3 SKECSPGQMKKTTRSQHICCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEK :..: : : ... ::.:: .::...:...:: : : . :. : :. : XP_005 SRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKCPDD-FWSNENHTSCIAK 390 400 410 420 430 440 590 600 610 620 630 640 pF1KE3 EVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFL :.:.:.:.. ..: : ....:::... : .: . :::.::... .. :..:. . XP_005 EIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNR-ELSYLLLFSLLC 450 460 470 480 490 650 660 670 680 690 700 pF1KE3 NFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCILTKSLKILLAF--SFDPKLQKFLKC :.:. ::::::::.::. :: ::.::.:::::::.:. ..::.: .. .... XP_005 CFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFEAKIPTSFHRKWWG 500 510 520 530 540 550 710 720 730 740 750 pF1KE3 LYRPILIIFTCTGIQVVICTLWLIFAAPTVEVNVSLP-RVIILECEEGSILAFGTMLGYI : .:..: :: .:.:::..:: : :. : : ..:.. :.:::..:.: ..:: XP_005 LNLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFITCHEGSLMALGFLIGYT 560 570 580 590 600 610 760 770 780 790 800 810 pF1KE3 AILAFICFIFAFKGKY--ENYNEAKFITFGMLIYFIAWITFIPIYATTFGKYVPAVEIIV .:: :::.::::.. ::.::::::::.:::.::.::.::: ::.:.::.: :::.:. XP_005 CLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTYGKFVSAVEVIA 620 630 640 650 660 670 820 830 840 850 860 870 pF1KE3 ILISNYGILYCTFIPKCYVIICKQEINT--KSAFLKMIYSYSSHSVSSIALSPASLDSMS :: ...:.: : :. : :.:. : :: . .... . ... : .: : XP_005 ILAASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKVAARATLRRSNVSRKRSS 680 690 700 710 720 730 880 890 900 910 920 pF1KE3 --GNVTMTNPSSS--GKSATW----QKSKDLQAQAFAHICRENATSVSKTLPRKRMSSI :. : ..:::: .:: . : .. : : .: . ... . :::... : XP_005 SLGGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLA-LTQQEQQQQPLTLPQQQRSQQQ 740 750 760 770 780 790 XP_005 PRCKQKVIFGSGTVTFSLSFDEPQKNAMAHRNSTHQNSLEAQKSSDTLTRHEPLLPLQCG 800 810 820 830 840 850 >>NP_000379 (OMIM: 145980,239200,601198,601199,612899) e (1078 aa) initn: 1247 init1: 462 opt: 737 Z-score: 782.9 bits: 156.4 E(85289): 7.2e-37 Smith-Waterman score: 1777; 33.1% identity (64.6% similar) in 970 aa overlap (5-924:1-956) 10 20 30 40 50 pF1KE3 MAFLIILITCFVIILATSQPCQT--PDDFVAATSPGHIIIGGLFAIHEKMLSSE-DSPRR . . .: ..:: . .. ::. : . : ::.:::: :: . ... : : NP_000 MAFYSCCWVLLALTWHTSAYGPDQ--RAQKKGDIILGGLFPIHFGVAAKDQDLKSR 10 20 30 40 50 60 70 80 90 100 110 pF1KE3 PQIQECVGFEISVFLQTLAMIHSIEMINNS-TLLSGVKLGYEIYDTCTEVTVAMAATLRF :. ::. ... : ::: .:: ::.: .:: .. :::.:.:::. :. :. ::: : NP_000 PESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE3 LSKFNCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEIL ... . . ... :. : ..: . ::.:. : .. ::. .:.: .:::.: :....: NP_000 VAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE3 SDKIRFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANN :.: .: :::::.:.: :: ::: .:. :::.: :..:::::: ... : .:: . NP_000 SNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 VCIAFKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNIN .:: :.:.. . :: : .:..... .: .. ..::::: . :... .. ::. NP_000 ICIDFSELISQY-SD---EEEIQHVVE-VIQNSTAKVIVVFSSGPDLEPLIKEIVRRNIT 240 250 260 270 280 300 310 320 330 340 350 pF1KE3 -KMWIASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLH :.:.::. :.... :. . .: ..:::.. :.: .:. ::...: : . . . NP_000 GKIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAK 290 300 310 320 330 340 360 370 380 390 400 pF1KE3 EYAMHLSAC-------------AYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDF :. . : .... . : :..: . :.. . ..:. . NP_000 EFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNS--STAFRPLCTGDENISSVETP 350 360 370 380 390 400 410 420 430 440 450 pF1KE3 LWDYAEPGLIHSIQLAVFALGYAIRDL--C-QAR------DCQNPNAFQPWELLGVLKNV ::.. . ... :::.....:..:. : .: .: . . . :..: :... NP_000 YIDYTHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHL 410 420 430 440 450 460 460 470 480 490 500 pF1KE3 TFTDGWN-SFHFDAHGDLNTGYDVVLWK--EINGHMTVTKMAEYDLQND----VFIIPDQ .::.. . . :: ::: .:... :. .: .. ... :.. .:: .. NP_000 NFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEK 470 480 490 500 510 520 510 520 530 540 550 560 pF1KE3 ETKNEFRNLKQIQ-SKCSKECSPGQMKKTTRSQHICCYECQNCPENHYTNQTDMPHCLLC . : ... :.::..: : : ... ::.:: .::...:...:: : : NP_000 ILWSGFS--REVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKC 530 540 550 560 570 580 570 580 590 600 610 620 pF1KE3 NNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPVVK . :. : :. ::.:.:.:.. ..: : ....:::... : .: . :::.:: NP_000 PDD-FWSNENHTSCIAKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVK 590 600 610 620 630 640 630 640 650 660 670 680 pF1KE3 SSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCILTKSLKIL ... .. :..:. . :.:. ::::::::.::. :: ::.::.:::::::.:. ..: NP_000 ATNR-ELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVL 650 660 670 680 690 700 690 700 710 720 730 740 pF1KE3 LAF--SFDPKLQKFLKCLYRPILIIFTCTGIQVVICTLWLIFAAPTVEVNVSLP-RVIIL :.: .. .... : .:..: :: .:.:::..:: : :. : : ..:.. NP_000 LVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFI 710 720 730 740 750 760 750 760 770 780 790 800 pF1KE3 ECEEGSILAFGTMLGYIAILAFICFIFAFKGKY--ENYNEAKFITFGMLIYFIAWITFIP :.:::..:.: ..:: .:: :::.::::.. ::.::::::::.:::.::.::.::: NP_000 TCHEGSLMALGFLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIP 770 780 790 800 810 820 810 820 830 840 850 pF1KE3 IYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQEINT--KSAFLKMIYSYSS ::.:.::.: :::.:.:: ...:.: : :. : :.:. : :: . .... NP_000 AYASTYGKFVSAVEVIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKV 830 840 850 860 870 880 860 870 880 890 900 910 pF1KE3 HSVSSIALSPASLDSMS--GNVTMTNPSSS--GKSATW----QKSKDLQAQAFAHICREN . ... : .: : :. : ..:::: .:: . : .. : : .: . ... NP_000 AARATLRRSNVSRKRSSSLGGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLA-LTQQE 890 900 910 920 930 940 920 pF1KE3 ATSVSKTLPRKRMSSI . :::... : NP_000 QQQQPLTLPQQQRSQQQPRCKQKVIFGSGTVTFSLSFDEPQKNAMAHRNSTHQNSLEAQK 950 960 970 980 990 1000 >>XP_016862813 (OMIM: 145980,239200,601198,601199,612899 (1078 aa) initn: 1247 init1: 462 opt: 737 Z-score: 782.9 bits: 156.4 E(85289): 7.2e-37 Smith-Waterman score: 1777; 33.1% identity (64.6% similar) in 970 aa overlap (5-924:1-956) 10 20 30 40 50 pF1KE3 MAFLIILITCFVIILATSQPCQT--PDDFVAATSPGHIIIGGLFAIHEKMLSSE-DSPRR . . .: ..:: . .. ::. : . : ::.:::: :: . ... : : XP_016 MAFYSCCWVLLALTWHTSAYGPDQ--RAQKKGDIILGGLFPIHFGVAAKDQDLKSR 10 20 30 40 50 60 70 80 90 100 110 pF1KE3 PQIQECVGFEISVFLQTLAMIHSIEMINNS-TLLSGVKLGYEIYDTCTEVTVAMAATLRF :. ::. ... : ::: .:: ::.: .:: .. :::.:.:::. :. :. ::: : XP_016 PESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE3 LSKFNCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEIL ... . . ... :. : ..: . ::.:. : .. ::. .:.: .:::.: :....: XP_016 VAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE3 SDKIRFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANN :.: .: :::::.:.: :: ::: .:. :::.: :..:::::: ... : .:: . XP_016 SNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 VCIAFKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNIN .:: :.:.. . :: : .:..... .: .. ..::::: . :... .. ::. XP_016 ICIDFSELISQY-SD---EEEIQHVVE-VIQNSTAKVIVVFSSGPDLEPLIKEIVRRNIT 240 250 260 270 280 300 310 320 330 340 350 pF1KE3 -KMWIASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLH :.:.::. :.... :. . .: ..:::.. :.: .:. ::...: : . . . XP_016 GKIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAK 290 300 310 320 330 340 360 370 380 390 400 pF1KE3 EYAMHLSAC-------------AYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDF :. . : .... . : :..: . :.. . ..:. . XP_016 EFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNS--STAFRPLCTGDENISSVETP 350 360 370 380 390 400 410 420 430 440 450 pF1KE3 LWDYAEPGLIHSIQLAVFALGYAIRDL--C-QAR------DCQNPNAFQPWELLGVLKNV ::.. . ... :::.....:..:. : .: .: . . . :..: :... XP_016 YIDYTHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHL 410 420 430 440 450 460 460 470 480 490 500 pF1KE3 TFTDGWN-SFHFDAHGDLNTGYDVVLWK--EINGHMTVTKMAEYDLQND----VFIIPDQ .::.. . . :: ::: .:... :. .: .. ... :.. .:: .. XP_016 NFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEK 470 480 490 500 510 520 510 520 530 540 550 560 pF1KE3 ETKNEFRNLKQIQ-SKCSKECSPGQMKKTTRSQHICCYECQNCPENHYTNQTDMPHCLLC . : ... :.::..: : : ... ::.:: .::...:...:: : : XP_016 ILWSGFS--REVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKC 530 540 550 560 570 580 570 580 590 600 610 620 pF1KE3 NNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPVVK . :. : :. ::.:.:.:.. ..: : ....:::... : .: . :::.:: XP_016 PDD-FWSNENHTSCIAKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVK 590 600 610 620 630 640 630 640 650 660 670 680 pF1KE3 SSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCILTKSLKIL ... .. :..:. . :.:. ::::::::.::. :: ::.::.:::::::.:. ..: XP_016 ATNR-ELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVL 650 660 670 680 690 700 690 700 710 720 730 740 pF1KE3 LAF--SFDPKLQKFLKCLYRPILIIFTCTGIQVVICTLWLIFAAPTVEVNVSLP-RVIIL :.: .. .... : .:..: :: .:.:::..:: : :. : : ..:.. XP_016 LVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFI 710 720 730 740 750 760 750 760 770 780 790 800 pF1KE3 ECEEGSILAFGTMLGYIAILAFICFIFAFKGKY--ENYNEAKFITFGMLIYFIAWITFIP :.:::..:.: ..:: .:: :::.::::.. ::.::::::::.:::.::.::.::: XP_016 TCHEGSLMALGFLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIP 770 780 790 800 810 820 810 820 830 840 850 pF1KE3 IYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQEINT--KSAFLKMIYSYSS ::.:.::.: :::.:.:: ...:.: : :. : :.:. : :: . .... XP_016 AYASTYGKFVSAVEVIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKV 830 840 850 860 870 880 860 870 880 890 900 910 pF1KE3 HSVSSIALSPASLDSMS--GNVTMTNPSSS--GKSATW----QKSKDLQAQAFAHICREN . ... : .: : :. : ..:::: .:: . : .. : : .: . ... XP_016 AARATLRRSNVSRKRSSSLGGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLA-LTQQE 890 900 910 920 930 940 920 pF1KE3 ATSVSKTLPRKRMSSI . :::... : XP_016 QQQQPLTLPQQQRSQQQPRCKQKVIFGSGTVTFSLSFDEPQKNAMAHRNSTHQNSLEAQK 950 960 970 980 990 1000 >>XP_006713852 (OMIM: 145980,239200,601198,601199,612899 (1078 aa) initn: 1247 init1: 462 opt: 737 Z-score: 782.9 bits: 156.4 E(85289): 7.2e-37 Smith-Waterman score: 1777; 33.1% identity (64.6% similar) in 970 aa overlap (5-924:1-956) 10 20 30 40 50 pF1KE3 MAFLIILITCFVIILATSQPCQT--PDDFVAATSPGHIIIGGLFAIHEKMLSSE-DSPRR . . .: ..:: . .. ::. : . : ::.:::: :: . ... : : XP_006 MAFYSCCWVLLALTWHTSAYGPDQ--RAQKKGDIILGGLFPIHFGVAAKDQDLKSR 10 20 30 40 50 60 70 80 90 100 110 pF1KE3 PQIQECVGFEISVFLQTLAMIHSIEMINNS-TLLSGVKLGYEIYDTCTEVTVAMAATLRF :. ::. ... : ::: .:: ::.: .:: .. :::.:.:::. :. :. ::: : XP_006 PESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE3 LSKFNCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEIL ... . . ... :. : ..: . ::.:. : .. ::. .:.: .:::.: :....: XP_006 VAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE3 SDKIRFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANN :.: .: :::::.:.: :: ::: .:. :::.: :..:::::: ... : .:: . XP_006 SNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 VCIAFKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNIN .:: :.:.. . :: : .:..... .: .. ..::::: . :... .. ::. XP_006 ICIDFSELISQY-SD---EEEIQHVVE-VIQNSTAKVIVVFSSGPDLEPLIKEIVRRNIT 240 250 260 270 280 300 310 320 330 340 350 pF1KE3 -KMWIASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLH :.:.::. :.... :. . .: ..:::.. :.: .:. ::...: : . . . XP_006 GKIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAK 290 300 310 320 330 340 360 370 380 390 400 pF1KE3 EYAMHLSAC-------------AYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDF :. . : .... . : :..: . :.. . ..:. . XP_006 EFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNS--STAFRPLCTGDENISSVETP 350 360 370 380 390 400 410 420 430 440 450 pF1KE3 LWDYAEPGLIHSIQLAVFALGYAIRDL--C-QAR------DCQNPNAFQPWELLGVLKNV ::.. . ... :::.....:..:. : .: .: . . . :..: :... XP_006 YIDYTHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHL 410 420 430 440 450 460 460 470 480 490 500 pF1KE3 TFTDGWN-SFHFDAHGDLNTGYDVVLWK--EINGHMTVTKMAEYDLQND----VFIIPDQ .::.. . . :: ::: .:... :. .: .. ... :.. .:: .. XP_006 NFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEK 470 480 490 500 510 520 510 520 530 540 550 560 pF1KE3 ETKNEFRNLKQIQ-SKCSKECSPGQMKKTTRSQHICCYECQNCPENHYTNQTDMPHCLLC . : ... :.::..: : : ... ::.:: .::...:...:: : : XP_006 ILWSGFS--REVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKC 530 540 550 560 570 580 570 580 590 600 610 620 pF1KE3 NNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPVVK . :. : :. ::.:.:.:.. ..: : ....:::... : .: . :::.:: XP_006 PDD-FWSNENHTSCIAKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVK 590 600 610 620 630 640 630 640 650 660 670 680 pF1KE3 SSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCILTKSLKIL ... .. :..:. . :.:. ::::::::.::. :: ::.::.:::::::.:. ..: XP_006 ATNR-ELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVL 650 660 670 680 690 700 690 700 710 720 730 740 pF1KE3 LAF--SFDPKLQKFLKCLYRPILIIFTCTGIQVVICTLWLIFAAPTVEVNVSLP-RVIIL :.: .. .... : .:..: :: .:.:::..:: : :. : : ..:.. XP_006 LVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFI 710 720 730 740 750 760 750 760 770 780 790 800 pF1KE3 ECEEGSILAFGTMLGYIAILAFICFIFAFKGKY--ENYNEAKFITFGMLIYFIAWITFIP :.:::..:.: ..:: .:: :::.::::.. ::.::::::::.:::.::.::.::: XP_006 TCHEGSLMALGFLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIP 770 780 790 800 810 820 810 820 830 840 850 pF1KE3 IYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQEINT--KSAFLKMIYSYSS ::.:.::.: :::.:.:: ...:.: : :. : :.:. : :: . .... XP_006 AYASTYGKFVSAVEVIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKV 830 840 850 860 870 880 860 870 880 890 900 910 pF1KE3 HSVSSIALSPASLDSMS--GNVTMTNPSSS--GKSATW----QKSKDLQAQAFAHICREN . ... : .: : :. : ..:::: .:: . : .. : : .: . ... XP_006 AARATLRRSNVSRKRSSSLGGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLA-LTQQE 890 900 910 920 930 940 920 pF1KE3 ATSVSKTLPRKRMSSI . :::... : XP_006 QQQQPLTLPQQQRSQQQPRCKQKVIFGSGTVTFSLSFDEPQKNAMAHRNSTHQNSLEAQK 950 960 970 980 990 1000 >>XP_016862814 (OMIM: 145980,239200,601198,601199,612899 (1078 aa) initn: 1247 init1: 462 opt: 737 Z-score: 782.9 bits: 156.4 E(85289): 7.2e-37 Smith-Waterman score: 1777; 33.1% identity (64.6% similar) in 970 aa overlap (5-924:1-956) 10 20 30 40 50 pF1KE3 MAFLIILITCFVIILATSQPCQT--PDDFVAATSPGHIIIGGLFAIHEKMLSSE-DSPRR . . .: ..:: . .. ::. : . : ::.:::: :: . ... : : XP_016 MAFYSCCWVLLALTWHTSAYGPDQ--RAQKKGDIILGGLFPIHFGVAAKDQDLKSR 10 20 30 40 50 60 70 80 90 100 110 pF1KE3 PQIQECVGFEISVFLQTLAMIHSIEMINNS-TLLSGVKLGYEIYDTCTEVTVAMAATLRF :. ::. ... : ::: .:: ::.: .:: .. :::.:.:::. :. :. ::: : XP_016 PESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE3 LSKFNCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEIL ... . . ... :. : ..: . ::.:. : .. ::. .:.: .:::.: :....: XP_016 VAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE3 SDKIRFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANN :.: .: :::::.:.: :: ::: .:. :::.: :..:::::: ... : .:: . XP_016 SNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 VCIAFKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNIN .:: :.:.. . :: : .:..... .: .. ..::::: . :... .. ::. XP_016 ICIDFSELISQY-SD---EEEIQHVVE-VIQNSTAKVIVVFSSGPDLEPLIKEIVRRNIT 240 250 260 270 280 300 310 320 330 340 350 pF1KE3 -KMWIASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLH :.:.::. :.... :. . .: ..:::.. :.: .:. ::...: : . . . XP_016 GKIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAK 290 300 310 320 330 340 360 370 380 390 400 pF1KE3 EYAMHLSAC-------------AYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDF :. . : .... . : :..: . :.. . ..:. . XP_016 EFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNS--STAFRPLCTGDENISSVETP 350 360 370 380 390 400 410 420 430 440 450 pF1KE3 LWDYAEPGLIHSIQLAVFALGYAIRDL--C-QAR------DCQNPNAFQPWELLGVLKNV ::.. . ... :::.....:..:. : .: .: . . . :..: :... XP_016 YIDYTHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHL 410 420 430 440 450 460 460 470 480 490 500 pF1KE3 TFTDGWN-SFHFDAHGDLNTGYDVVLWK--EINGHMTVTKMAEYDLQND----VFIIPDQ .::.. . . :: ::: .:... :. .: .. ... :.. .:: .. XP_016 NFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEK 470 480 490 500 510 520 510 520 530 540 550 560 pF1KE3 ETKNEFRNLKQIQ-SKCSKECSPGQMKKTTRSQHICCYECQNCPENHYTNQTDMPHCLLC . : ... :.::..: : : ... ::.:: .::...:...:: : : XP_016 ILWSGFS--REVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKC 530 540 550 560 570 580 570 580 590 600 610 620 pF1KE3 NNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPVVK . :. : :. ::.:.:.:.. ..: : ....:::... : .: . :::.:: XP_016 PDD-FWSNENHTSCIAKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVK 590 600 610 620 630 640 630 640 650 660 670 680 pF1KE3 SSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCILTKSLKIL ... .. :..:. . :.:. ::::::::.::. :: ::.::.:::::::.:. ..: XP_016 ATNR-ELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVL 650 660 670 680 690 700 690 700 710 720 730 740 pF1KE3 LAF--SFDPKLQKFLKCLYRPILIIFTCTGIQVVICTLWLIFAAPTVEVNVSLP-RVIIL :.: .. .... : .:..: :: .:.:::..:: : :. : : ..:.. XP_016 LVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFI 710 720 730 740 750 760 750 760 770 780 790 800 pF1KE3 ECEEGSILAFGTMLGYIAILAFICFIFAFKGKY--ENYNEAKFITFGMLIYFIAWITFIP :.:::..:.: ..:: .:: :::.::::.. ::.::::::::.:::.::.::.::: XP_016 TCHEGSLMALGFLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIP 770 780 790 800 810 820 810 820 830 840 850 pF1KE3 IYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQEINT--KSAFLKMIYSYSS ::.:.::.: :::.:.:: ...:.: : :. : :.:. : :: . .... XP_016 AYASTYGKFVSAVEVIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKV 830 840 850 860 870 880 860 870 880 890 900 910 pF1KE3 HSVSSIALSPASLDSMS--GNVTMTNPSSS--GKSATW----QKSKDLQAQAFAHICREN . ... : .: : :. : ..:::: .:: . : .. : : .: . ... XP_016 AARATLRRSNVSRKRSSSLGGSTGSTPSSSISSKSNSEDPFPQPERQKQQQPLA-LTQQE 890 900 910 920 930 940 920 pF1KE3 ATSVSKTLPRKRMSSI . :::... : XP_016 QQQQPLTLPQQQRSQQQPRCKQKVIFGSGTVTFSLSFDEPQKNAMAHRNSTHQNSLEAQK 950 960 970 980 990 1000 926 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 19:38:45 2016 done: Mon Nov 7 19:38:46 2016 Total Scan time: 7.600 Total Display time: 0.270 Function used was FASTA [36.3.4 Apr, 2011]