FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3703, 1679 aa 1>>>pF1KE3703 1679 - 1679 aa - 1679 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 17.9458+/-0.000492; mu= -35.3936+/- 0.031 mean_var=808.7522+/-170.448, 0's: 0 Z-trim(125.7): 320 B-trim: 1738 in 1/60 Lambda= 0.045099 statistics sampled from 49433 (49876) to 49433 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.585), width: 16 Scan time: 24.270 The best scores are: opt bits E(85289) XP_011522054 (OMIM: 611577) PREDICTED: lysine-spec (1682) 11797 784.2 0 NP_001073893 (OMIM: 611577) lysine-specific demeth (1682) 11797 784.2 0 XP_005256608 (OMIM: 611577) PREDICTED: lysine-spec (1682) 11797 784.2 0 XP_005256609 (OMIM: 611577) PREDICTED: lysine-spec (1682) 11797 784.2 0 XP_005256606 (OMIM: 611577) PREDICTED: lysine-spec (1682) 11797 784.2 0 XP_011522052 (OMIM: 611577) PREDICTED: lysine-spec (1682) 11797 784.2 0 XP_006721546 (OMIM: 611577) PREDICTED: lysine-spec (1682) 11797 784.2 0 XP_005256607 (OMIM: 611577) PREDICTED: lysine-spec (1682) 11797 784.2 0 XP_016879870 (OMIM: 611577) PREDICTED: lysine-spec (1643) 11488 764.1 0 XP_016885274 (OMIM: 147920,300128,300867) PREDICTE (1071) 2367 170.5 7e-41 NP_001278350 (OMIM: 147920,300128,300867) lysine-s (1105) 2367 170.6 7.2e-41 NP_001278347 (OMIM: 147920,300128,300867) lysine-s (1322) 2367 170.6 8.3e-41 NP_001278346 (OMIM: 147920,300128,300867) lysine-s (1356) 2367 170.6 8.5e-41 XP_005272716 (OMIM: 147920,300128,300867) PREDICTE (1367) 2367 170.6 8.5e-41 XP_016885272 (OMIM: 147920,300128,300867) PREDICTE (1374) 2367 170.6 8.6e-41 XP_011542275 (OMIM: 147920,300128,300867) PREDICTE (1375) 2367 170.6 8.6e-41 XP_011542273 (OMIM: 147920,300128,300867) PREDICTE (1393) 2367 170.6 8.7e-41 NP_066963 (OMIM: 147920,300128,300867) lysine-spec (1401) 2367 170.6 8.7e-41 NP_001278345 (OMIM: 147920,300128,300867) lysine-s (1408) 2367 170.6 8.7e-41 XP_005272713 (OMIM: 147920,300128,300867) PREDICTE (1419) 2367 170.6 8.8e-41 XP_011542269 (OMIM: 147920,300128,300867) PREDICTE (1420) 2367 170.6 8.8e-41 XP_016885271 (OMIM: 147920,300128,300867) PREDICTE (1427) 2367 170.6 8.8e-41 NP_001278344 (OMIM: 147920,300128,300867) lysine-s (1453) 2367 170.6 9e-41 XP_011542262 (OMIM: 147920,300128,300867) PREDICTE (1472) 2367 170.6 9.1e-41 NP_001245199 (OMIM: 400009) histone demethylase UT (1218) 2349 169.4 1.8e-40 NP_001245197 (OMIM: 400009) histone demethylase UT (1263) 2349 169.4 1.8e-40 NP_001245198 (OMIM: 400009) histone demethylase UT (1293) 2349 169.4 1.8e-40 XP_016885558 (OMIM: 400009) PREDICTED: histone dem (1342) 2349 169.4 1.9e-40 NP_001245196 (OMIM: 400009) histone demethylase UT (1342) 2349 169.4 1.9e-40 XP_016885556 (OMIM: 400009) PREDICTED: histone dem (1387) 2349 169.4 1.9e-40 XP_016885563 (OMIM: 400009) PREDICTED: histone dem (1433) 2349 169.5 2e-40 XP_011529759 (OMIM: 400009) PREDICTED: histone dem (1455) 2349 169.5 2e-40 XP_011529757 (OMIM: 400009) PREDICTED: histone dem (1455) 2349 169.5 2e-40 NP_001245179 (OMIM: 400009) histone demethylase UT (1207) 2344 169.1 2.2e-40 NP_001245186 (OMIM: 400009) histone demethylase UT (1223) 2344 169.1 2.2e-40 NP_001245194 (OMIM: 400009) histone demethylase UT (1264) 2344 169.1 2.3e-40 NP_001245184 (OMIM: 400009) histone demethylase UT (1268) 2344 169.1 2.3e-40 NP_001245191 (OMIM: 400009) histone demethylase UT (1320) 2344 169.1 2.3e-40 NP_001245188 (OMIM: 400009) histone demethylase UT (1331) 2344 169.1 2.4e-40 NP_009056 (OMIM: 400009) histone demethylase UTY i (1347) 2344 169.1 2.4e-40 XP_016885557 (OMIM: 400009) PREDICTED: histone dem (1347) 2344 169.1 2.4e-40 NP_001245180 (OMIM: 400009) histone demethylase UT (1363) 2344 169.1 2.4e-40 NP_001245193 (OMIM: 400009) histone demethylase UT (1376) 2344 169.1 2.4e-40 NP_001245189 (OMIM: 400009) histone demethylase UT (1377) 2344 169.1 2.4e-40 NP_001245190 (OMIM: 400009) histone demethylase UT (1389) 2344 169.1 2.4e-40 NP_001245181 (OMIM: 400009) histone demethylase UT (1392) 2344 169.1 2.4e-40 NP_001245187 (OMIM: 400009) histone demethylase UT (1399) 2344 169.1 2.5e-40 XP_016885555 (OMIM: 400009) PREDICTED: histone dem (1422) 2344 169.1 2.5e-40 XP_011529760 (OMIM: 400009) PREDICTED: histone dem (1422) 2344 169.1 2.5e-40 NP_001245178 (OMIM: 400009) histone demethylase UT (1444) 2344 169.1 2.5e-40 >>XP_011522054 (OMIM: 611577) PREDICTED: lysine-specific (1682 aa) initn: 10000 init1: 10000 opt: 11797 Z-score: 4168.0 bits: 784.2 E(85289): 0 Smith-Waterman score: 11797; 99.8% identity (99.8% similar) in 1682 aa overlap (1-1679:1-1682) 10 20 30 40 50 60 pF1KE3 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 PPGLPLPPPPLPPPPPPPPPP---LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_011 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE3 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE3 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE3 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE3 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE3 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE3 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE3 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE3 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE3 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE3 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE3 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE3 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE3 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE3 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE3 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE3 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE3 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE3 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE3 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE3 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1630 1640 1650 1660 1670 1680 pF1KE3 SR :: XP_011 SR >>NP_001073893 (OMIM: 611577) lysine-specific demethylas (1682 aa) initn: 10000 init1: 10000 opt: 11797 Z-score: 4168.0 bits: 784.2 E(85289): 0 Smith-Waterman score: 11797; 99.8% identity (99.8% similar) in 1682 aa overlap (1-1679:1-1682) 10 20 30 40 50 60 pF1KE3 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 PPGLPLPPPPLPPPPPPPPPP---LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: NP_001 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE3 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE3 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE3 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE3 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE3 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE3 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE3 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE3 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE3 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE3 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE3 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE3 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE3 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE3 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE3 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE3 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE3 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE3 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE3 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE3 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1630 1640 1650 1660 1670 1680 pF1KE3 SR :: NP_001 SR >>XP_005256608 (OMIM: 611577) PREDICTED: lysine-specific (1682 aa) initn: 10000 init1: 10000 opt: 11797 Z-score: 4168.0 bits: 784.2 E(85289): 0 Smith-Waterman score: 11797; 99.8% identity (99.8% similar) in 1682 aa overlap (1-1679:1-1682) 10 20 30 40 50 60 pF1KE3 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 PPGLPLPPPPLPPPPPPPPPP---LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_005 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE3 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE3 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE3 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE3 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE3 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE3 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE3 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE3 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE3 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE3 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE3 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE3 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE3 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE3 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE3 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE3 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE3 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE3 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE3 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE3 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1630 1640 1650 1660 1670 1680 pF1KE3 SR :: XP_005 SR >>XP_005256609 (OMIM: 611577) PREDICTED: lysine-specific (1682 aa) initn: 10000 init1: 10000 opt: 11797 Z-score: 4168.0 bits: 784.2 E(85289): 0 Smith-Waterman score: 11797; 99.8% identity (99.8% similar) in 1682 aa overlap (1-1679:1-1682) 10 20 30 40 50 60 pF1KE3 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 PPGLPLPPPPLPPPPPPPPPP---LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_005 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE3 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE3 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE3 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE3 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE3 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE3 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE3 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE3 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE3 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE3 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE3 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE3 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE3 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE3 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE3 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE3 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE3 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE3 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE3 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE3 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1630 1640 1650 1660 1670 1680 pF1KE3 SR :: XP_005 SR >>XP_005256606 (OMIM: 611577) PREDICTED: lysine-specific (1682 aa) initn: 10000 init1: 10000 opt: 11797 Z-score: 4168.0 bits: 784.2 E(85289): 0 Smith-Waterman score: 11797; 99.8% identity (99.8% similar) in 1682 aa overlap (1-1679:1-1682) 10 20 30 40 50 60 pF1KE3 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 PPGLPLPPPPLPPPPPPPPPP---LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_005 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE3 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE3 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE3 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE3 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE3 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE3 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE3 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE3 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE3 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE3 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE3 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE3 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE3 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE3 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE3 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE3 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE3 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE3 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE3 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE3 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1630 1640 1650 1660 1670 1680 pF1KE3 SR :: XP_005 SR >>XP_011522052 (OMIM: 611577) PREDICTED: lysine-specific (1682 aa) initn: 10000 init1: 10000 opt: 11797 Z-score: 4168.0 bits: 784.2 E(85289): 0 Smith-Waterman score: 11797; 99.8% identity (99.8% similar) in 1682 aa overlap (1-1679:1-1682) 10 20 30 40 50 60 pF1KE3 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 PPGLPLPPPPLPPPPPPPPPP---LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_011 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE3 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE3 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE3 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE3 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE3 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE3 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE3 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE3 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE3 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE3 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE3 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE3 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE3 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE3 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE3 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE3 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE3 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE3 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE3 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE3 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1630 1640 1650 1660 1670 1680 pF1KE3 SR :: XP_011 SR >>XP_006721546 (OMIM: 611577) PREDICTED: lysine-specific (1682 aa) initn: 10000 init1: 10000 opt: 11797 Z-score: 4168.0 bits: 784.2 E(85289): 0 Smith-Waterman score: 11797; 99.8% identity (99.8% similar) in 1682 aa overlap (1-1679:1-1682) 10 20 30 40 50 60 pF1KE3 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 PPGLPLPPPPLPPPPPPPPPP---LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_006 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE3 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE3 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE3 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE3 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE3 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE3 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE3 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE3 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE3 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE3 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE3 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE3 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE3 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE3 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE3 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE3 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE3 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE3 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE3 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE3 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1630 1640 1650 1660 1670 1680 pF1KE3 SR :: XP_006 SR >>XP_005256607 (OMIM: 611577) PREDICTED: lysine-specific (1682 aa) initn: 10000 init1: 10000 opt: 11797 Z-score: 4168.0 bits: 784.2 E(85289): 0 Smith-Waterman score: 11797; 99.8% identity (99.8% similar) in 1682 aa overlap (1-1679:1-1682) 10 20 30 40 50 60 pF1KE3 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 PPGLPLPPPPLPPPPPPPPPP---LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_005 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE3 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE3 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE3 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE3 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE3 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE3 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE3 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE3 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE3 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE3 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE3 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE3 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE3 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE3 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE3 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE3 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE3 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE3 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE3 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE3 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1630 1640 1650 1660 1670 1680 pF1KE3 SR :: XP_005 SR >>XP_016879870 (OMIM: 611577) PREDICTED: lysine-specific (1643 aa) initn: 11682 init1: 9679 opt: 11488 Z-score: 4059.5 bits: 764.1 E(85289): 0 Smith-Waterman score: 11488; 99.5% identity (99.6% similar) in 1643 aa overlap (1-1640:1-1643) 10 20 30 40 50 60 pF1KE3 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 PPGLPLPPPPLPPPPPPPPPP---LPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_016 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE3 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE3 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE3 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE3 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE3 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE3 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE3 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE3 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE3 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE3 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE3 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE3 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE3 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE3 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE3 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE3 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE3 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE3 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE3 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE3 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE3 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE3 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE3 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST ::::::::::::::::. : .: XP_016 QYRTEELAQAYDAFTLAPASTSR 1630 1640 >>XP_016885274 (OMIM: 147920,300128,300867) PREDICTED: l (1071 aa) initn: 2341 init1: 1674 opt: 2367 Z-score: 854.9 bits: 170.5 E(85289): 7e-41 Smith-Waterman score: 2415; 44.3% identity (67.5% similar) in 942 aa overlap (708-1633:165-1062) 680 690 700 710 720 730 pF1KE3 QFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQ---SPFP .:: : ..:: .: . : . .: XP_016 NTSALAARIKYLQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQMRPTGVAQVRSTGIP 140 150 160 170 180 190 740 750 760 770 780 790 pF1KE3 TDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPP . . .. :. .:. . : . . . :: : : :: . : : XP_016 NGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQP-LA-----NGPFSAGHVP 200 210 220 230 240 800 810 820 830 840 850 pF1KE3 PSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PSGATALPPTSAAP- : . : : ..: :... :.:. : .: : . : . : : .. : XP_016 CSTSRTLGSTDTILIGNNH-ITGSGSN-----GNVPYLQRNALTLPHNRTNLTSSAEEPW 250 260 270 280 290 300 860 870 880 890 900 pF1KE3 SAQGSPQPSASSSSQFSTSGGPWARERRAGEEP-----VPGPMTPTQPPPPLSLPPAR-S . : : . .. ..: : :.:: ... .. : . : .: : .:: . XP_016 KNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHP-TLPSNSVT 310 320 330 340 350 360 910 920 930 940 950 960 pF1KE3 ESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVS .. .:...: : . : . : . : ::. .: ......: . . XP_016 QGAALNHLSSHTATSGGQQGITLTKESKP--------SGNILTVP--ETSRHTGETPNST 370 380 390 400 410 970 980 990 1000 1010 1020 pF1KE3 GSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEI- .: : .: .. : :.: : .: .:. . . ... . . .... XP_016 ASV-----EGLPNHVHQMTA--DAVCS-PSHGDSKSPGLLSSDNPQLSALLMGKANNNVG 420 430 440 450 460 1030 1040 1050 1060 1070 1080 pF1KE3 QGREKSRPDLGGASKAKPPTAPAP-PSAPAPSAQPTPPSASVPGKKAREEAPGP-PGVSR : . .. : ..: .. : ::. .: :.: :. .. .: :. XP_016 TGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHT 470 480 490 500 510 520 1090 1100 1110 1120 1130 1140 pF1KE3 ADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAADVVRAS . .. :..: .: :. :. . .: : ...: .:.:..: XP_016 INGEGMEE-SQSP---MKTDLLLVNHKPSPQIIPS---------MSVSIYPSSAEVLKAC 530 540 550 560 570 1150 1160 1170 1180 1190 1200 pF1KE3 RNAKVKGKFRESYL-SPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFC :: .: : : . .: . ::..::::::::::::.::::: : : ::: XP_016 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 580 590 600 610 620 630 1210 1220 1230 1240 1250 1260 pF1KE3 TDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQI :.: ::.::::::::.:.:.::::::::::::..:: ::::::. ::.::::: :::..: XP_016 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 640 650 660 670 680 690 1270 1280 1290 1300 1310 1320 pF1KE3 WPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDPKN-HH : :::.:::::::::::::::::::::.::.:........ :: . . .:. :. . XP_016 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK 700 710 720 730 740 750 1330 1340 1350 1360 1370 1380 pF1KE3 IIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPG ::::::::::: :.:: ::.:: :::::.::.:.::.:::::::::::::::::::::: XP_016 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG 760 770 780 790 800 810 1390 1400 1410 1420 1430 1440 pF1KE3 SRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDL :::::::::::::::::::::::::::.: : :: ... ::.......: ::::: :.:: XP_016 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL 820 830 840 850 860 870 1450 1460 1470 1480 1490 1500 pF1KE3 YASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNE : .:.:::::.::::::::::::::::::: ::::::::::::::: ::.::.::::::. XP_016 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK 880 890 900 910 920 930 1510 1520 1530 1540 1550 1560 pF1KE3 VKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQ ...:::::::.:.:::.::..:.::: ::.:::.:::...:.::. ::.:. :::.: .. XP_016 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH 940 950 960 970 980 990 1570 1580 1590 1600 1610 1620 pF1KE3 GRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLEQYRT ::.:.:::.::. :.::::..::::.:..::.::.:::. :::. :..:.. ::::::. XP_016 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM 1000 1010 1020 1030 1040 1050 1630 1640 1650 1660 1670 pF1KE3 EELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPASTSR :.: :.:: ::: XP_016 EDLMQVYDQFTLAPPLPSASS 1060 1070 1679 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:14:31 2016 done: Sat Nov 5 19:14:35 2016 Total Scan time: 24.270 Total Display time: 1.090 Function used was FASTA [36.3.4 Apr, 2011]