FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3818, 1182 aa 1>>>pF1KE3818 1182 - 1182 aa - 1182 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0019+/-0.00115; mu= 3.0507+/- 0.068 mean_var=407.5163+/-88.403, 0's: 0 Z-trim(112.7): 653 B-trim: 0 in 0/56 Lambda= 0.063533 statistics sampled from 12902 (13638) to 12902 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.408), width: 16 Scan time: 2.740 The best scores are: opt bits E(33420) CCDS30947.1 ABL2 gene_id:27|Hs109|chr1 (1182) 7914 741.2 3.6e-213 CCDS41441.2 ABL2 gene_id:27|Hs109|chr1 (1167) 7554 708.2 3.1e-203 CCDS53436.1 ABL2 gene_id:27|Hs109|chr1 (1161) 7402 694.2 4.8e-199 CCDS53438.1 ABL2 gene_id:27|Hs109|chr1 (1079) 4614 438.6 3.8e-122 CCDS44282.1 ABL2 gene_id:27|Hs109|chr1 (1064) 4254 405.6 3.3e-112 CCDS53437.1 ABL2 gene_id:27|Hs109|chr1 (1058) 4102 391.7 5.1e-108 CCDS53435.1 ABL2 gene_id:27|Hs109|chr1 (1043) 4101 391.6 5.4e-108 CCDS35166.1 ABL1 gene_id:25|Hs109|chr9 (1130) 3371 324.7 7.9e-88 CCDS35165.1 ABL1 gene_id:25|Hs109|chr9 (1149) 3371 324.7 7.9e-88 CCDS44283.1 ABL2 gene_id:27|Hs109|chr1 ( 542) 3213 309.9 1.1e-83 CCDS5095.1 FYN gene_id:2534|Hs109|chr6 ( 534) 1275 132.2 3.3e-30 CCDS5094.1 FYN gene_id:2534|Hs109|chr6 ( 537) 1269 131.7 4.9e-30 CCDS11824.1 YES1 gene_id:7525|Hs109|chr18 ( 543) 1259 130.8 9.3e-30 CCDS305.1 FGR gene_id:2268|Hs109|chr1 ( 529) 1256 130.5 1.1e-29 CCDS13294.1 SRC gene_id:6714|Hs109|chr20 ( 536) 1251 130.0 1.5e-29 CCDS359.1 LCK gene_id:3932|Hs109|chr1 ( 509) 1230 128.1 5.6e-29 CCDS54456.1 HCK gene_id:3055|Hs109|chr20 ( 504) 1218 127.0 1.2e-28 CCDS54453.1 HCK gene_id:3055|Hs109|chr20 ( 525) 1218 127.0 1.2e-28 CCDS54455.1 HCK gene_id:3055|Hs109|chr20 ( 505) 1216 126.8 1.4e-28 CCDS33460.1 HCK gene_id:3055|Hs109|chr20 ( 526) 1216 126.8 1.4e-28 CCDS5103.1 FRK gene_id:2444|Hs109|chr6 ( 505) 1196 125.0 4.9e-28 CCDS5982.1 BLK gene_id:640|Hs109|chr8 ( 505) 1186 124.0 9.2e-28 CCDS47859.1 LYN gene_id:4067|Hs109|chr8 ( 491) 1178 123.3 1.5e-27 CCDS6162.1 LYN gene_id:4067|Hs109|chr8 ( 512) 1169 122.5 2.7e-27 CCDS14482.1 BTK gene_id:695|Hs109|chrX ( 659) 1147 120.6 1.3e-26 CCDS76003.1 BTK gene_id:695|Hs109|chrX ( 693) 1147 120.6 1.3e-26 CCDS83251.1 BLK gene_id:640|Hs109|chr8 ( 434) 1139 119.6 1.6e-26 CCDS3481.1 TEC gene_id:7006|Hs109|chr4 ( 631) 1136 119.6 2.5e-26 CCDS3480.1 TXK gene_id:7294|Hs109|chr4 ( 527) 1103 116.4 1.8e-25 CCDS10269.1 CSK gene_id:1445|Hs109|chr15 ( 450) 1094 115.5 2.9e-25 CCDS13525.1 SRMS gene_id:6725|Hs109|chr20 ( 488) 1038 110.5 1.1e-23 CCDS13524.1 PTK6 gene_id:5753|Hs109|chr20 ( 451) 1008 107.7 6.9e-23 CCDS14168.1 BMX gene_id:660|Hs109|chrX ( 675) 991 106.3 2.6e-22 CCDS4336.1 ITK gene_id:3702|Hs109|chr5 ( 620) 970 104.3 9.5e-22 CCDS78044.1 FER gene_id:2241|Hs109|chr5 ( 453) 851 93.3 1.5e-18 CCDS4098.1 FER gene_id:2241|Hs109|chr5 ( 822) 851 93.6 2.2e-18 CCDS45351.1 FES gene_id:2242|Hs109|chr15 ( 694) 814 90.1 2.1e-17 CCDS45349.1 FES gene_id:2242|Hs109|chr15 ( 752) 814 90.1 2.2e-17 CCDS45350.1 FES gene_id:2242|Hs109|chr15 ( 764) 814 90.2 2.2e-17 CCDS10365.1 FES gene_id:2242|Hs109|chr15 ( 822) 814 90.2 2.3e-17 CCDS5096.1 FYN gene_id:2534|Hs109|chr6 ( 482) 800 88.6 4e-17 CCDS6058.1 PTK2B gene_id:2185|Hs109|chr8 ( 967) 753 84.7 1.2e-15 CCDS42468.1 MATK gene_id:4145|Hs109|chr19 ( 466) 744 83.5 1.4e-15 CCDS12114.1 MATK gene_id:4145|Hs109|chr19 ( 507) 744 83.5 1.4e-15 CCDS12113.1 MATK gene_id:4145|Hs109|chr19 ( 508) 744 83.5 1.4e-15 CCDS6381.1 PTK2 gene_id:5747|Hs109|chr8 (1052) 738 83.4 3.4e-15 CCDS56557.1 PTK2 gene_id:5747|Hs109|chr8 (1065) 738 83.4 3.4e-15 CCDS6057.1 PTK2B gene_id:2185|Hs109|chr8 (1009) 729 82.5 5.8e-15 CCDS42811.1 ERBB4 gene_id:2066|Hs109|chr2 (1292) 731 82.8 6e-15 CCDS2394.1 ERBB4 gene_id:2066|Hs109|chr2 (1308) 731 82.8 6e-15 >>CCDS30947.1 ABL2 gene_id:27|Hs109|chr1 (1182 aa) initn: 7914 init1: 7914 opt: 7914 Z-score: 3940.8 bits: 741.2 E(33420): 3.6e-213 Smith-Waterman score: 7914; 100.0% identity (100.0% similar) in 1182 aa overlap (1-1182:1-1182) 10 20 30 40 50 60 pF1KE3 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 DGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 DGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE3 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE3 TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE3 NSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 NSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE3 NAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 NAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE3 SFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE3 SNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEES 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE3 AAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 AAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE3 MAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE3 LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE3 GGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 GGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE3 ADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 ADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KE3 SKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR :::::::::::::::::::::::::::::::::::::::::: CCDS30 SKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR 1150 1160 1170 1180 >>CCDS41441.2 ABL2 gene_id:27|Hs109|chr1 (1167 aa) initn: 7554 init1: 7554 opt: 7554 Z-score: 3762.5 bits: 708.2 E(33420): 3.1e-203 Smith-Waterman score: 7554; 100.0% identity (100.0% similar) in 1130 aa overlap (53-1182:38-1167) 30 40 50 60 70 80 pF1KE3 RGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVEDGFEGDKTGGSSPEALHRPYGC :::::::::::::::::::::::::::::: CCDS41 LPPNSYGRDQDTSLCCLCTEASESALPDLTDHFASCVEDGFEGDKTGGSSPEALHRPYGC 10 20 30 40 50 60 90 100 110 120 130 140 pF1KE3 DVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQN 70 80 90 100 110 120 150 160 170 180 190 200 pF1KE3 GEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESES 130 140 150 160 170 180 210 220 230 240 250 260 pF1KE3 SPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYP 190 200 210 220 230 240 270 280 290 300 310 320 pF1KE3 APKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 APKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED 250 260 270 280 290 300 330 340 350 360 370 380 pF1KE3 TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT 310 320 330 340 350 360 390 400 410 420 430 440 pF1KE3 AVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAH 370 380 390 400 410 420 450 460 470 480 490 500 pF1KE3 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 430 440 450 460 470 480 510 520 530 540 550 560 pF1KE3 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASS 490 500 510 520 530 540 570 580 590 600 610 620 pF1KE3 SSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPA 550 560 570 580 590 600 630 640 650 660 670 680 pF1KE3 LPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKK 610 620 630 640 650 660 690 700 710 720 730 740 pF1KE3 YELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGGSFAQRNLCNDDGGGGGGSGTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGGSFAQRNLCNDDGGGGGGSGTAG 670 680 690 700 710 720 750 760 770 780 790 800 pF1KE3 GGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLP 730 740 750 760 770 780 810 820 830 840 850 860 pF1KE3 RNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPL 790 800 810 820 830 840 870 880 890 900 910 920 pF1KE3 RTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPV 850 860 870 880 890 900 930 940 950 960 970 980 pF1KE3 LPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKC 910 920 930 940 950 960 990 1000 1010 1020 1030 1040 pF1KE3 APPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPVMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 APPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPVMP 970 980 990 1000 1010 1020 1050 1060 1070 1080 1090 1100 pF1KE3 PPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSALTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSALTE 1030 1040 1050 1060 1070 1080 1110 1120 1130 1140 1150 1160 pF1KE3 PVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGVPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGVPGT 1090 1100 1110 1120 1130 1140 1170 1180 pF1KE3 NPVLNNLLSCVQEISDVVQR :::::::::::::::::::: CCDS41 NPVLNNLLSCVQEISDVVQR 1150 1160 >>CCDS53436.1 ABL2 gene_id:27|Hs109|chr1 (1161 aa) initn: 7401 init1: 7401 opt: 7402 Z-score: 3687.2 bits: 694.2 E(33420): 4.8e-199 Smith-Waterman score: 7709; 98.2% identity (98.2% similar) in 1182 aa overlap (1-1182:1-1161) 10 20 30 40 50 60 pF1KE3 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVE :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQH-------- 10 20 30 40 50 70 80 90 100 110 120 pF1KE3 DGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA ::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 -------------EALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA 60 70 80 90 130 140 150 160 170 180 pF1KE3 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE3 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE3 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE3 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE3 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE3 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE3 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE 460 470 480 490 500 510 550 560 570 580 590 600 pF1KE3 TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE 520 530 540 550 560 570 610 620 630 640 650 660 pF1KE3 NSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR 580 590 600 610 620 630 670 680 690 700 710 720 pF1KE3 NAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGG 640 650 660 670 680 690 730 740 750 760 770 780 pF1KE3 SFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPR 700 710 720 730 740 750 790 800 810 820 830 840 pF1KE3 SNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEES 760 770 780 790 800 810 850 860 870 880 890 900 pF1KE3 AAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLG 820 830 840 850 860 870 910 920 930 940 950 960 pF1KE3 MAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KE3 LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQE 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KE3 GGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 GGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KE3 ADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 pF1KE3 SKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR :::::::::::::::::::::::::::::::::::::::::: CCDS53 SKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR 1120 1130 1140 1150 1160 >>CCDS53438.1 ABL2 gene_id:27|Hs109|chr1 (1079 aa) initn: 4653 init1: 4614 opt: 4614 Z-score: 2306.5 bits: 438.6 E(33420): 3.8e-122 Smith-Waterman score: 6990; 91.3% identity (91.3% similar) in 1182 aa overlap (1-1182:1-1079) 10 20 30 40 50 60 pF1KE3 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 DGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE3 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE3 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE3 TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE3 NSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE3 NAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGG ::::::::::::::::::::::::::: CCDS53 NAPTPPKRSSSFREMENQPHKKYELTG--------------------------------- 670 680 730 740 750 760 770 780 pF1KE3 SFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPR CCDS53 ------------------------------------------------------------ 790 800 810 820 830 840 pF1KE3 SNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEES :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ----------LPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEES 690 700 710 720 730 850 860 870 880 890 900 pF1KE3 AAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLG 740 750 760 770 780 790 910 920 930 940 950 960 pF1KE3 MAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL 800 810 820 830 840 850 970 980 990 1000 1010 1020 pF1KE3 LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQE 860 870 880 890 900 910 1030 1040 1050 1060 1070 1080 pF1KE3 GGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 GGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS 920 930 940 950 960 970 1090 1100 1110 1120 1130 1140 pF1KE3 ADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV 980 990 1000 1010 1020 1030 1150 1160 1170 1180 pF1KE3 SKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR :::::::::::::::::::::::::::::::::::::::::: CCDS53 SKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR 1040 1050 1060 1070 >>CCDS44282.1 ABL2 gene_id:27|Hs109|chr1 (1064 aa) initn: 4293 init1: 4254 opt: 4254 Z-score: 2128.2 bits: 405.6 E(33420): 3.3e-112 Smith-Waterman score: 6630; 90.9% identity (90.9% similar) in 1130 aa overlap (53-1182:38-1064) 30 40 50 60 70 80 pF1KE3 RGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVEDGFEGDKTGGSSPEALHRPYGC :::::::::::::::::::::::::::::: CCDS44 LPPNSYGRDQDTSLCCLCTEASESALPDLTDHFASCVEDGFEGDKTGGSSPEALHRPYGC 10 20 30 40 50 60 90 100 110 120 130 140 pF1KE3 DVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQN 70 80 90 100 110 120 150 160 170 180 190 200 pF1KE3 GEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESES 130 140 150 160 170 180 210 220 230 240 250 260 pF1KE3 SPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYP 190 200 210 220 230 240 270 280 290 300 310 320 pF1KE3 APKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 APKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED 250 260 270 280 290 300 330 340 350 360 370 380 pF1KE3 TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT 310 320 330 340 350 360 390 400 410 420 430 440 pF1KE3 AVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAH 370 380 390 400 410 420 450 460 470 480 490 500 pF1KE3 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 430 440 450 460 470 480 510 520 530 540 550 560 pF1KE3 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASS 490 500 510 520 530 540 570 580 590 600 610 620 pF1KE3 SSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPA 550 560 570 580 590 600 630 640 650 660 670 680 pF1KE3 LPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKK 610 620 630 640 650 660 690 700 710 720 730 740 pF1KE3 YELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGGSFAQRNLCNDDGGGGGGSGTAG ::::: CCDS44 YELTG------------------------------------------------------- 670 750 760 770 780 790 800 pF1KE3 GGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLP :::::::::::: CCDS44 ------------------------------------------------LPEQDRMAMTLP 680 810 820 830 840 850 860 pF1KE3 RNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPL 690 700 710 720 730 740 870 880 890 900 910 920 pF1KE3 RTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPV 750 760 770 780 790 800 930 940 950 960 970 980 pF1KE3 LPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKC 810 820 830 840 850 860 990 1000 1010 1020 1030 1040 pF1KE3 APPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPVMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 APPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPVMP 870 880 890 900 910 920 1050 1060 1070 1080 1090 1100 pF1KE3 PPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSALTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSALTE 930 940 950 960 970 980 1110 1120 1130 1140 1150 1160 pF1KE3 PVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGVPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGVPGT 990 1000 1010 1020 1030 1040 1170 1180 pF1KE3 NPVLNNLLSCVQEISDVVQR :::::::::::::::::::: CCDS44 NPVLNNLLSCVQEISDVVQR 1050 1060 >>CCDS53437.1 ABL2 gene_id:27|Hs109|chr1 (1058 aa) initn: 4140 init1: 4101 opt: 4102 Z-score: 2053.0 bits: 391.7 E(33420): 5.1e-108 Smith-Waterman score: 6785; 89.5% identity (89.5% similar) in 1182 aa overlap (1-1182:1-1058) 10 20 30 40 50 60 pF1KE3 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVE :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQH-------- 10 20 30 40 50 70 80 90 100 110 120 pF1KE3 DGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA ::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 -------------EALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA 60 70 80 90 130 140 150 160 170 180 pF1KE3 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE3 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE3 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE3 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE3 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE3 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE3 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE 460 470 480 490 500 510 550 560 570 580 590 600 pF1KE3 TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE 520 530 540 550 560 570 610 620 630 640 650 660 pF1KE3 NSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR 580 590 600 610 620 630 670 680 690 700 710 720 pF1KE3 NAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGG ::::::::::::::::::::::::::: CCDS53 NAPTPPKRSSSFREMENQPHKKYELTG--------------------------------- 640 650 660 730 740 750 760 770 780 pF1KE3 SFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPR CCDS53 ------------------------------------------------------------ 790 800 810 820 830 840 pF1KE3 SNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEES :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ----------LPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEES 670 680 690 700 710 850 860 870 880 890 900 pF1KE3 AAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLG 720 730 740 750 760 770 910 920 930 940 950 960 pF1KE3 MAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL 780 790 800 810 820 830 970 980 990 1000 1010 1020 pF1KE3 LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQE 840 850 860 870 880 890 1030 1040 1050 1060 1070 1080 pF1KE3 GGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 GGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS 900 910 920 930 940 950 1090 1100 1110 1120 1130 1140 pF1KE3 ADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV 960 970 980 990 1000 1010 1150 1160 1170 1180 pF1KE3 SKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR :::::::::::::::::::::::::::::::::::::::::: CCDS53 SKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR 1020 1030 1040 1050 >>CCDS53435.1 ABL2 gene_id:27|Hs109|chr1 (1043 aa) initn: 4140 init1: 4101 opt: 4101 Z-score: 2052.5 bits: 391.6 E(33420): 5.4e-108 Smith-Waterman score: 6477; 90.7% identity (90.7% similar) in 1109 aa overlap (74-1182:38-1043) 50 60 70 80 90 100 pF1KE3 TGFNIFTQHDHFASCVEDGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLG :::::::::::::::::::::::::::::: CCDS53 LPPNSYGRDQDTSLCCLCTEASESALPDLTEALHRPYGCDVEPQALNEAIRWSSKENLLG 10 20 30 40 50 60 110 120 130 140 150 160 pF1KE3 ATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYIT 70 80 90 100 110 120 170 180 190 200 210 220 pF1KE3 PVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRIN 130 140 150 160 170 180 230 240 250 260 270 280 pF1KE3 TTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEM 190 200 210 220 230 240 290 300 310 320 330 340 pF1KE3 ERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPN 250 260 270 280 290 300 350 360 370 380 390 400 pF1KE3 LVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 LVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKK 310 320 330 340 350 360 410 420 430 440 450 460 pF1KE3 NFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 NFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFS 370 380 390 400 410 420 470 480 490 500 510 520 pF1KE3 IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 IKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWK 430 440 450 460 470 480 530 540 550 560 570 580 pF1KE3 WSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 WSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLK 490 500 510 520 530 540 590 600 610 620 630 640 pF1KE3 KQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETC 550 560 570 580 590 600 650 660 670 680 690 700 pF1KE3 FTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSF :::::::::::::::::::::::::::::::::::::::::::: CCDS53 FTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKKYELTG---------------- 610 620 630 640 650 710 720 730 740 750 760 pF1KE3 TPAQQEANLVPPKCYGGSFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGL CCDS53 ------------------------------------------------------------ 770 780 790 800 810 820 pF1KE3 RAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPE ::::::::::::::::::::::::::::::::: CCDS53 ---------------------------LPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPE 660 670 680 830 840 850 860 870 880 pF1KE3 ENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAG 690 700 710 720 730 740 890 900 910 920 930 940 pF1KE3 VAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTP 750 760 770 780 790 800 950 960 970 980 990 1000 pF1KE3 ADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPT 810 820 830 840 850 860 1010 1020 1030 1040 1050 1060 pF1KE3 EEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 EEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTA 870 880 890 900 910 920 1070 1080 1090 1100 1110 1120 pF1KE3 GTKVALRKTKQAAEKISADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 GTKVALRKTKQAAEKISADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGY 930 940 950 960 970 980 1130 1140 1150 1160 1170 1180 pF1KE3 VDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR 990 1000 1010 1020 1030 1040 >>CCDS35166.1 ABL1 gene_id:25|Hs109|chr9 (1130 aa) initn: 3269 init1: 2813 opt: 3371 Z-score: 1690.5 bits: 324.7 E(33420): 7.9e-88 Smith-Waterman score: 3643; 54.5% identity (72.5% similar) in 1162 aa overlap (74-1182:27-1130) 50 60 70 80 90 100 pF1KE3 TGFNIFTQHDHFASCVEDGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLL- :::.:: . : :::.:.:: ::.:::::: CCDS35 MLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLA 10 20 30 40 50 110 120 130 140 150 160 pF1KE3 GATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYI : .:.:::::::::::::::::::::::::::::::::.:::: :...:::::::::::: CCDS35 GPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYI 60 70 80 90 100 110 170 180 190 200 210 220 pF1KE3 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRI ::::::::::::::::::.:::::::: :::::::::::::::: ::::::::::::::: CCDS35 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRI 120 130 140 150 160 170 230 240 250 260 270 280 pF1KE3 NTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWE ::..:::.::..::::.::::::::::::::::.::::::::: :::::::::: .:::: CCDS35 NTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWE 180 190 200 210 220 230 290 300 310 320 330 340 pF1KE3 MERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHP ::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::: CCDS35 MERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHP 240 250 260 270 280 290 350 360 370 380 390 400 pF1KE3 NLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEK :::::::::: ::::::.::.: :::::::::::::.::.:::::::::::::::::::: CCDS35 NLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEK 300 310 320 330 340 350 410 420 430 440 450 460 pF1KE3 KNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTF :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: : CCDS35 KNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKF 360 370 380 390 400 410 470 480 490 500 510 520 pF1KE3 SIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACW :::::::::::::::::::::::::::::::::.:::: ::::.::::: :::::::::: CCDS35 SIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACW 420 430 440 450 460 470 530 540 550 560 570 580 pF1KE3 KWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTL .:.:.::::::: ::::::::..::::.:: .:::. . ..: : . : ::.:::: CCDS35 QWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLL-QAPELPTKTRTS 480 490 500 510 520 530 590 600 610 620 630 640 pF1KE3 KKQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKET .. .:.... . . .. . : . . :: ::::.: ..: :: : CCDS35 RRAAEHRDTTDVPEMPHSKGQGESDPL----DHEPAVSPLLPRKERGPPEGGLNED--ER 540 550 560 570 580 650 660 670 680 690 700 pF1KE3 CFTRDRKGGFFSSFMKKRN--APTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADG . .:.: ..::...::.. ::::::::::::::..::... . .... . CCDS35 LLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISN----GA 590 600 610 620 630 640 710 720 730 740 750 760 pF1KE3 FSFTPAQQEANLVPPKCYGGSFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKT ..::: . :: .:. : .:. .:: .:: .:.: ::. CCDS35 LAFTPLDTADPAKSPKPSNGA-----------GVPNGALRESGG----SGFRSPHLWKKS 650 660 670 680 690 770 780 790 800 810 pF1KE3 LGLRA-----GKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERT : . :. .. ..:: : :: :.: . : . . ..::::. : . :.. . CCDS35 STLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSS 700 710 720 730 740 750 820 830 840 850 860 870 pF1KE3 VSTSSQPEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPLR-TPSGDLAITE- . . . :. . ::.: :. .: . . ::... : : . ... : : CCDS35 TFGGHKSEKPA------LPRKR---AGENR----SDQVTRGTVTPPPRLVKKNEEAADEV 760 770 780 790 880 890 900 910 920 pF1KE3 -KD----PPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPTTHN :: :: . ... : .. . . :. : :. . .:: : :: ::. CCDS35 FKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTS-- 800 810 820 830 840 850 930 940 950 960 970 980 pF1KE3 HKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSG-DKDRPRRVKPKCAPPPP :. .. ::. .:. . : :. : : :: . :.:: ::::: CCDS35 -KAGSGAPGGTSKGPAE------ESRVRRHK----HSSESPGRDKGKLSRLKP--APPPP 860 870 880 890 900 990 1000 1010 1020 pF1KE3 PVMRLLQHPSICSDPTEEPTALTAGQST---------------------SETQEGGKKAA :. . . . :.. :. .::... :. :: :: . CCDS35 PAA---SAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPV 910 920 930 940 950 1030 1040 1050 1060 1070 pF1KE3 LGAVPISGKA---GRPVMPPPQVP--LPTSSISPA-KMANGTA-----GTKVALRKTKQA : :.: .: : :. : : :: ::..: . : . ..:: .:.:.::::.: CCDS35 LPATPKPQSAKPSGTPISPAP-VPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQP 960 970 980 990 1000 1010 1080 1090 1100 1110 1120 1130 pF1KE3 AEKISADKISKEALLECADLLSSALT----EPVPNSQLVDTGHQLLDYCSGYVDCIPQTR :.:.. :.: ..:. .. : :.. . . .: ....:..: .: .::: : : : CCDS35 PERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMR 1020 1030 1040 1050 1060 1070 1140 1150 1160 1170 1180 pF1KE3 NKFAFREAVSKLELSLQELQVSSAAAGV-PGTNPVLNNLLSCVQEISDVVQR ::::::::..::: .:.:::. :.:: :... ...::: :.::::.::: CCDS35 NKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR 1080 1090 1100 1110 1120 1130 >>CCDS35165.1 ABL1 gene_id:25|Hs109|chr9 (1149 aa) initn: 3269 init1: 2813 opt: 3371 Z-score: 1690.4 bits: 324.7 E(33420): 7.9e-88 Smith-Waterman score: 3646; 52.5% identity (70.4% similar) in 1236 aa overlap (1-1182:1-1149) 10 20 30 40 50 pF1KE3 MGQQVGRV-GEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCV :::: :.: :. . : . :.:.. . :.:. : :.:..: CCDS35 MGQQPGKVLGDQRRPSLPALHFIKGAGK-KESSRHGGP-------HCNVFVEH------- 10 20 30 40 60 70 80 90 100 110 pF1KE3 EDGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLL-GATESDPNLFVALYDF :::.:: . : :::.:.:: ::.:::::: : .:.::::::::::: CCDS35 --------------EALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDF 50 60 70 80 90 120 130 140 150 160 170 pF1KE3 VASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPV ::::::::::::::::::::::.:::: :...:::::::::::::::::::::::::::: CCDS35 VASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPV 100 110 120 130 140 150 180 190 200 210 220 230 pF1KE3 SRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRF ::.:::::::: :::::::::::::::: :::::::::::::::::..:::.::..:::: CCDS35 SRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRF 160 170 180 190 200 210 240 250 260 270 280 290 pF1KE3 STLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQ .::::::::::::::::.::::::::: :::::::::: .:::::::::::::::::::: CCDS35 NTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQ 220 230 240 250 260 270 300 310 320 330 340 350 pF1KE3 YGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFY ::::: :::::::::::::::::::::::::::::::::::::::::::::::: ::::: CCDS35 YGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFY 280 290 300 310 320 330 360 370 380 390 400 410 pF1KE3 IVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG :.::.: :::::::::::::.::.:::::::::::::::::::::::::::::::::::: CCDS35 IITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG 340 350 360 370 380 390 420 430 440 450 460 470 pF1KE3 ENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEI :::.:::::::::::::::::::::::::::::::::::::: ::::::::::::::::: CCDS35 ENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEI 400 410 420 430 440 450 480 490 500 510 520 530 pF1KE3 ATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQA :::::::::::::::::.:::: ::::.::::: ::::::::::.:.:.::::::: ::: CCDS35 ATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQA 460 470 480 490 500 510 540 550 560 570 580 590 pF1KE3 FETMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDA :::::..::::.:: .:::. . ..: : . : ::.:::: .. .:.... . . CCDS35 FETMFQESSISDEVEKELGKQGVRGAVSTLL-QAPELPTKTRTSRRAAEHRDTTDVPEMP 520 530 540 550 560 570 600 610 620 630 640 650 pF1KE3 TENSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMK .. . : . . :: ::::.: ..: :: : . .:.: ..::...: CCDS35 HSKGQGESDPL----DHEPAVSPLLPRKERGPPEGGLNED--ERLLPKDKKTNLFSALIK 580 590 600 610 620 660 670 680 690 700 710 pF1KE3 KRN--APTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPK :.. ::::::::::::::..::... . .... ...::: . :: CCDS35 KKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISN----GALAFTPLDTADPAKSPK 630 640 650 660 670 680 720 730 740 750 760 770 pF1KE3 CYGGSFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRA-----GKPTAS .:. : .:. .:: .:: .:.: ::. : . :. .. CCDS35 PSNGA-----------GVPNGALRESGG----SGFRSPHLWKKSSTLTSSRLATGEEEGG 690 700 710 720 780 790 800 810 820 830 pF1KE3 DDTSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRAND ..:: : :: :.: . : . . ..::::. : . :.. .. . . :. CCDS35 GSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEK------P 730 740 750 760 770 840 850 860 870 880 pF1KE3 MLPKKSEESAAPSRERPKAKLLPRGATALPLR-TPSGDLAITE--KD----PPGVGVAGV ::.: :. .: . . ::... : : . ... : : :: :: . .. CCDS35 ALPRK---RAGENR----SDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNL 780 790 800 810 820 830 890 900 910 920 930 940 pF1KE3 AAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPA . : .. . . :. : :. . .:: : :: ::. :. .. :: CCDS35 TPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTS---KAGSGAPGGTSKGPA 840 850 860 870 880 950 960 970 980 990 1000 pF1KE3 DVQLIGTDSQGNKFKLLSEHQVTSSG-DKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPT . .:. . : :. : : :: . :.:: ::::::. . . . :. CCDS35 E------ESRVRRHK----HSSESPGRDKGKLSRLKP--APPPPPAA---SAGKAGGKPS 890 900 910 920 930 1010 1020 1030 pF1KE3 EEPTALTAGQST---------------------SETQEGGKKAALGAVPISGKA---GRP . :. .::... :. :: :: .: :.: .: : : CCDS35 QSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTP 940 950 960 970 980 990 1040 1050 1060 1070 1080 1090 pF1KE3 VMPPPQVP--LPTSSISPA-KMANGTA-----GTKVALRKTKQAAEKISADKISKEALLE . : : :: ::..: . : . ..:: .:.:.::::.: :.:.. :.: ..:. CCDS35 ISPAP-VPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLD 1000 1010 1020 1030 1040 1050 1100 1110 1120 1130 1140 pF1KE3 CADLLSSALT----EPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSL .. : :.. . . .: ....:..: .: .::: : : :::::::::..::: .: CCDS35 STEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 pF1KE3 QELQVSSAAAGV-PGTNPVLNNLLSCVQEISDVVQR .:::. :.:: :... ...::: :.::::.::: CCDS35 RELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR 1120 1130 1140 >>CCDS44283.1 ABL2 gene_id:27|Hs109|chr1 (542 aa) initn: 3247 init1: 3212 opt: 3213 Z-score: 1615.9 bits: 309.9 E(33420): 1.1e-83 Smith-Waterman score: 3520; 96.2% identity (96.2% similar) in 550 aa overlap (1-550:1-529) 10 20 30 40 50 60 pF1KE3 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVE :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQH-------- 10 20 30 40 50 70 80 90 100 110 120 pF1KE3 DGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA ::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 -------------EALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA 60 70 80 90 130 140 150 160 170 180 pF1KE3 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE3 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFST 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE3 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE3 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE3 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE3 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE3 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE 460 470 480 490 500 510 550 560 570 580 590 600 pF1KE3 TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE :::::::::: CCDS44 TMFHDSSISEVLLHCANQTCITL 520 530 540 1182 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:49:49 2019 done: Thu Oct 24 21:49:50 2019 Total Scan time: 2.740 Total Display time: 0.300 Function used was FASTA [36.3.4 Apr, 2011]