FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE3935, 466 aa 1>>>pF1KE3935 466 - 466 aa - 466 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.4740+/-0.000949; mu= -3.5202+/- 0.058 mean_var=302.5414+/-62.198, 0's: 0 Z-trim(115.3): 22 B-trim: 2 in 1/52 Lambda= 0.073736 statistics sampled from 15799 (15817) to 15799 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.486), width: 16 Scan time: 3.760 The best scores are: opt bits E(32554) CCDS4319.1 G3BP1 gene_id:10146|Hs108|chr5 ( 466) 3191 352.6 5.1e-97 CCDS3571.1 G3BP2 gene_id:9908|Hs108|chr4 ( 482) 1600 183.3 4.7e-46 CCDS3572.1 G3BP2 gene_id:9908|Hs108|chr4 ( 449) 1025 122.2 1.1e-27 >>CCDS4319.1 G3BP1 gene_id:10146|Hs108|chr5 (466 aa) initn: 3191 init1: 3191 opt: 3191 Z-score: 1855.2 bits: 352.6 E(32554): 5.1e-97 Smith-Waterman score: 3191; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466) 10 20 30 40 50 60 pF1KE3 MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 IHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 IHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE3 ANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQAVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQAVVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE3 NDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADIAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADIAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE3 TVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE3 QRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE3 QSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAARE 370 380 390 400 410 420 430 440 450 460 pF1KE3 GDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRGLAPRQ :::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRGLAPRQ 430 440 450 460 >>CCDS3571.1 G3BP2 gene_id:9908|Hs108|chr4 (482 aa) initn: 1595 init1: 860 opt: 1600 Z-score: 940.3 bits: 183.3 E(32554): 4.7e-46 Smith-Waterman score: 1981; 65.4% identity (80.3% similar) in 482 aa overlap (1-461:1-471) 10 20 30 40 50 60 pF1KE3 MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKE ::::::::::::::::::::::::.::..::::::.::::::::.:..::: .:::::.. CCDS35 MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 IHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSV ::.::.: ::..::::::::::::::.:::::::::::::..: :.::::::::::::: CCDS35 IHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSV 70 80 90 100 110 120 130 140 150 160 170 pF1KE3 ANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEP-EERQQTPEVVPDDSGT-FYDQAV ::::::::.:::.::::: : .::::.:::: :::: .:: : ..... .:. CCDS35 PNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE3 VSNDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADI :.: .:: ::: ::::.:: : . : : ::. : :.. : .::..: ::. CCDS35 VTNGIEEPLEESSHEPEPEPESETKTE------ELKPQ-VEEKNLEELEEKSTTPPPAEP 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 AQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQ .. :: ..:::::::::::::::.: .:::::: :.:.:::: :.::: : : : CCDS35 VSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHV-KAPVSQPRVEAKPEVQSQPPRV- 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE3 RDQRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKD :.:: :: : ..:: ::::: : ::.: . ::..:.:::::::.:::::..:..:::. CCDS35 REQRPRE-RPGFPP-RGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKE 300 310 320 330 340 360 370 380 390 400 410 pF1KE3 FFQSYGNVVELRINS---GGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKT ::.:.:::::::::. :::::::::::::::::::..: .::::::::::::::::: CCDS35 FFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKT 350 360 370 380 390 400 420 430 440 450 pF1KE3 RAARE-------GDRRDNRL--RGPGGPRGGLGGGM------RGPP-RGGMVQKPGFGVG ::::: :::: : :::::::: .:::: :::: ::::.:: : : : CCDS35 RAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRG 410 420 430 440 450 460 460 pF1KE3 RGLAPRQ : CCDS35 TGQMEGRFTGQRR 470 480 >>CCDS3572.1 G3BP2 gene_id:9908|Hs108|chr4 (449 aa) initn: 1446 init1: 860 opt: 1025 Z-score: 610.2 bits: 122.2 E(32554): 1.1e-27 Smith-Waterman score: 1745; 60.4% identity (74.3% similar) in 482 aa overlap (1-461:1-438) 10 20 30 40 50 60 pF1KE3 MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKE ::::::::::::::::::::::::.::..::::::.::::::::.:..::: .:::::.. CCDS35 MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE3 IHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSV ::.::.: ::..::::::::::::::.:::::::::::::..: :.::::::::::::: CCDS35 IHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSV 70 80 90 100 110 120 130 140 150 160 170 pF1KE3 ANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEP-EERQQTPEVVPDDSGT-FYDQAV ::::::::.:::.::::: : .::::.:::: :::: .:: : ..... .:. CCDS35 PNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE3 VSNDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADI :.: .:: ::: ::::.:: : . : : ::. : :.. : .::..: ::. CCDS35 VTNGIEEPLEESSHEPEPEPESETKTE------ELKPQ-VEEKNLEELEEKSTTPPPAEP 190 200 210 220 230 240 250 260 270 280 290 pF1KE3 AQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQ .. :: :: .:: :.::: : : : CCDS35 VSLPQE---------------PP-------------------KPRVEAKPEVQSQPPRV- 240 250 300 310 320 330 340 350 pF1KE3 RDQRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKD :.:: :: : ..:: ::::: : ::.: . ::..:.:::::::.:::::..:..:::. CCDS35 REQRPRE-RPGFPP-RGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKE 260 270 280 290 300 310 360 370 380 390 400 410 pF1KE3 FFQSYGNVVELRINS---GGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKT ::.:.:::::::::. :::::::::::::::::::..: .::::::::::::::::: CCDS35 FFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKT 320 330 340 350 360 370 420 430 440 450 pF1KE3 RAARE-------GDRRDNRL--RGPGGPRGGLGGGM------RGPP-RGGMVQKPGFGVG ::::: :::: : :::::::: .:::: :::: ::::.:: : : : CCDS35 RAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRG 380 390 400 410 420 430 460 pF1KE3 RGLAPRQ : CCDS35 TGQMEGRFTGQRR 440 466 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 18 17:34:33 2016 done: Fri Nov 18 17:34:34 2016 Total Scan time: 3.760 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]