FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE4045, 267 aa 1>>>pF1KE4045 267 - 267 aa - 267 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6855+/-0.000748; mu= 12.4148+/- 0.044 mean_var=64.1525+/-13.134, 0's: 0 Z-trim(107.6): 127 B-trim: 0 in 0/50 Lambda= 0.160128 statistics sampled from 9686 (9817) to 9686 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.294), width: 16 Scan time: 1.050 The best scores are: opt bits E(33420) CCDS32185.1 ARHGAP11B gene_id:89839|Hs109|chr15 ( 267) 1784 420.6 5.6e-118 CCDS58349.1 ARHGAP11A gene_id:9824|Hs109|chr15 ( 501) 1440 341.3 8.3e-94 CCDS10028.1 ARHGAP11A gene_id:9824|Hs109|chr15 (1023) 1440 341.4 1.6e-93 CCDS76261.1 SRGAP2 gene_id:23380|Hs109|chr1 ( 789) 293 76.3 7.3e-14 CCDS76262.1 SRGAP2 gene_id:23380|Hs109|chr1 (1070) 293 76.4 9.7e-14 CCDS73017.1 SRGAP2 gene_id:23380|Hs109|chr1 (1071) 293 76.4 9.7e-14 CCDS14736.1 ARHGAP4 gene_id:393|Hs109|chrX ( 946) 292 76.1 1e-13 CCDS55540.1 ARHGAP4 gene_id:393|Hs109|chrX ( 986) 292 76.1 1.1e-13 CCDS58079.1 ARHGAP22 gene_id:58504|Hs109|chr10 ( 608) 288 75.2 1.3e-13 CCDS7227.1 ARHGAP22 gene_id:58504|Hs109|chr10 ( 698) 288 75.2 1.5e-13 CCDS58081.1 ARHGAP22 gene_id:58504|Hs109|chr10 ( 704) 288 75.2 1.5e-13 CCDS58080.1 ARHGAP22 gene_id:58504|Hs109|chr10 ( 714) 286 74.7 2.1e-13 CCDS55201.1 DLC1 gene_id:10395|Hs109|chr8 (1017) 283 74.1 4.6e-13 CCDS5990.1 DLC1 gene_id:10395|Hs109|chr8 (1091) 283 74.1 4.9e-13 CCDS83253.1 DLC1 gene_id:10395|Hs109|chr8 (1125) 283 74.1 5e-13 CCDS82076.1 ARHGAP44 gene_id:9912|Hs109|chr17 ( 774) 280 73.3 5.8e-13 CCDS82077.1 ARHGAP44 gene_id:9912|Hs109|chr17 ( 812) 280 73.3 6e-13 CCDS45616.1 ARHGAP44 gene_id:9912|Hs109|chr17 ( 818) 280 73.3 6.1e-13 CCDS5989.1 DLC1 gene_id:10395|Hs109|chr8 (1528) 283 74.1 6.7e-13 CCDS7922.1 ARHGAP1 gene_id:392|Hs109|chr11 ( 439) 270 71.0 1.7e-12 CCDS8967.1 SRGAP1 gene_id:57522|Hs109|chr12 (1085) 272 71.5 2.8e-12 CCDS34535.1 ARHGAP18 gene_id:93663|Hs109|chr6 ( 663) 269 70.8 2.9e-12 CCDS2572.1 SRGAP3 gene_id:9901|Hs109|chr3 (1099) 269 70.8 4.6e-12 CCDS14390.1 STARD8 gene_id:9754|Hs109|chrX (1023) 261 69.0 1.6e-11 CCDS48134.1 STARD8 gene_id:9754|Hs109|chrX (1103) 261 69.0 1.7e-11 CCDS43246.1 ARHGAP24 gene_id:83478|Hs109|chr4 ( 653) 257 68.0 2e-11 CCDS32408.1 ARHGAP17 gene_id:55114|Hs109|chr16 ( 803) 258 68.3 2e-11 CCDS32409.1 ARHGAP17 gene_id:55114|Hs109|chr16 ( 881) 258 68.3 2.2e-11 CCDS34025.1 ARHGAP24 gene_id:83478|Hs109|chr4 ( 748) 257 68.0 2.2e-11 CCDS33689.1 SRGAP3 gene_id:9901|Hs109|chr3 (1075) 259 68.5 2.3e-11 CCDS14060.2 ARHGAP8 gene_id:23779|Hs109|chr22 ( 433) 252 66.8 3e-11 CCDS33664.1 ARHGAP8 gene_id:23779|Hs109|chr22 ( 464) 252 66.8 3.2e-11 CCDS54538.2 ARHGAP8 gene_id:553158|Hs109|chr22 ( 564) 252 66.8 3.8e-11 CCDS13952.2 SH3BP1 gene_id:23616|Hs109|chr22 ( 701) 253 67.1 4e-11 CCDS34029.1 FAM13A gene_id:10144|Hs109|chr4 (1023) 254 67.4 4.8e-11 CCDS3611.1 ARHGAP24 gene_id:83478|Hs109|chr4 ( 655) 247 65.7 9.8e-11 >>CCDS32185.1 ARHGAP11B gene_id:89839|Hs109|chr15 (267 aa) initn: 1784 init1: 1784 opt: 1784 Z-score: 2231.7 bits: 420.6 E(33420): 5.6e-118 Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 267 aa overlap (1-267:1-267) 10 20 30 40 50 60 pF1KE4 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVS 190 200 210 220 230 240 250 260 pF1KE4 VLLHHWKALKKVNMKLLVNIREREDNV ::::::::::::::::::::::::::: CCDS32 VLLHHWKALKKVNMKLLVNIREREDNV 250 260 >>CCDS58349.1 ARHGAP11A gene_id:9824|Hs109|chr15 (501 aa) initn: 1439 init1: 1439 opt: 1440 Z-score: 1797.8 bits: 341.3 E(33420): 8.3e-94 Smith-Waterman score: 1440; 95.2% identity (97.0% similar) in 231 aa overlap (1-226:1-231) 10 20 30 40 50 60 pF1KE4 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: CCDS58 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: CCDS58 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 130 140 150 160 170 180 190 200 210 220 230 pF1KE4 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKK-----GVYQTLSWKRYQPCW ::::::::::::::::::::::::::::::::::::.::: .: ::: CCDS58 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 190 200 210 220 230 240 240 250 260 pF1KE4 VLMVSVLLHHWKALKKVNMKLLVNIREREDNV CCDS58 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 250 260 270 280 290 300 >>CCDS10028.1 ARHGAP11A gene_id:9824|Hs109|chr15 (1023 aa) initn: 1439 init1: 1439 opt: 1440 Z-score: 1792.7 bits: 341.4 E(33420): 1.6e-93 Smith-Waterman score: 1440; 95.2% identity (97.0% similar) in 231 aa overlap (1-226:1-231) 10 20 30 40 50 60 pF1KE4 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: CCDS10 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: CCDS10 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 130 140 150 160 170 180 190 200 210 220 230 pF1KE4 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKK-----GVYQTLSWKRYQPCW ::::::::::::::::::::::::::::::::::::.::: .: ::: CCDS10 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 190 200 210 220 230 240 240 250 260 pF1KE4 VLMVSVLLHHWKALKKVNMKLLVNIREREDNV CCDS10 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 250 260 270 280 290 300 >>CCDS76261.1 SRGAP2 gene_id:23380|Hs109|chr1 (789 aa) initn: 280 init1: 147 opt: 293 Z-score: 362.5 bits: 76.3 E(33420): 7.3e-14 Smith-Waterman score: 293; 33.7% identity (65.7% similar) in 169 aa overlap (65-226:503-670) 40 50 60 70 80 90 pF1KE4 HETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTS-LEEH-IHTEGLFRKSGSV :: ..:..: . .: .. ::.:: ::: CCDS76 LQKTLGESQRTDCSLARRSSTVRKQDSSQAIP-LVVESCIRFISRHGLQHEGIFRVSGSQ 480 490 500 510 520 530 100 110 120 130 140 pF1KE4 IRLKALKNKVDHGEGCLSSAP---PCD-IAGLLKQFFRELPEPILPADL-HEALLKAQQL .... .:: ..:: :.. : :::.:: .:: : .:..: :. :. . . . CCDS76 VEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMD 540 550 560 570 580 590 150 160 170 180 190 200 pF1KE4 GTEEKNKAILLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTS . .:. : . .: :. ..::.: :: ..: : :: :: :::. :.:.:... CCDS76 NLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVP 600 610 620 630 640 650 210 220 230 240 250 260 pF1KE4 EGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV :::...: .:. . . .:. CCDS76 EGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVED 660 670 680 690 700 710 >>CCDS76262.1 SRGAP2 gene_id:23380|Hs109|chr1 (1070 aa) initn: 280 init1: 147 opt: 293 Z-score: 360.4 bits: 76.4 E(33420): 9.7e-14 Smith-Waterman score: 293; 33.7% identity (65.7% similar) in 169 aa overlap (65-226:503-670) 40 50 60 70 80 90 pF1KE4 HETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTS-LEEH-IHTEGLFRKSGSV :: ..:..: . .: .. ::.:: ::: CCDS76 LQKTLGESQRTDCSLARRSSTVRKQDSSQAIP-LVVESCIRFISRHGLQHEGIFRVSGSQ 480 490 500 510 520 530 100 110 120 130 140 pF1KE4 IRLKALKNKVDHGEGCLSSAP---PCD-IAGLLKQFFRELPEPILPADL-HEALLKAQQL .... .:: ..:: :.. : :::.:: .:: : .:..: :. :. . . . CCDS76 VEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMD 540 550 560 570 580 590 150 160 170 180 190 200 pF1KE4 GTEEKNKAILLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTS . .:. : . .: :. ..::.: :: ..: : :: :: :::. :.:.:... CCDS76 NLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVP 600 610 620 630 640 650 210 220 230 240 250 260 pF1KE4 EGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV :::...: .:. . . .:. CCDS76 EGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVED 660 670 680 690 700 710 >>CCDS73017.1 SRGAP2 gene_id:23380|Hs109|chr1 (1071 aa) initn: 280 init1: 147 opt: 293 Z-score: 360.3 bits: 76.4 E(33420): 9.7e-14 Smith-Waterman score: 293; 33.7% identity (65.7% similar) in 169 aa overlap (65-226:504-671) 40 50 60 70 80 90 pF1KE4 HETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTS-LEEH-IHTEGLFRKSGSV :: ..:..: . .: .. ::.:: ::: CCDS73 LQKTLGESQRTDCSLARRSSTVRKQDSSQAIP-LVVESCIRFISRHGLQHEGIFRVSGSQ 480 490 500 510 520 530 100 110 120 130 140 pF1KE4 IRLKALKNKVDHGEGCLSSAP---PCD-IAGLLKQFFRELPEPILPADL-HEALLKAQQL .... .:: ..:: :.. : :::.:: .:: : .:..: :. :. . . . CCDS73 VEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMD 540 550 560 570 580 590 150 160 170 180 190 200 pF1KE4 GTEEKNKAILLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTS . .:. : . .: :. ..::.: :: ..: : :: :: :::. :.:.:... CCDS73 NLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVP 600 610 620 630 640 650 210 220 230 240 250 260 pF1KE4 EGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV :::...: .:. . . .:. CCDS73 EGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVED 660 670 680 690 700 710 >>CCDS14736.1 ARHGAP4 gene_id:393|Hs109|chrX (946 aa) initn: 152 init1: 152 opt: 292 Z-score: 360.0 bits: 76.1 E(33420): 1e-13 Smith-Waterman score: 292; 30.4% identity (62.3% similar) in 204 aa overlap (32-226:490-687) 10 20 30 40 50 60 pF1KE4 WDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVPE . :. ... . ..:: .. . .:. CCDS14 KHEKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSS--- 460 470 480 490 500 510 70 80 90 100 110 pF1KE4 YGHIPSFLVDACTSL--EEHIHTEGLFRKSGSVIRLKALKNKVDHGE-----GCLSSAPP :. ..:..: . . .. ::.:: ::. .:.. ... ..:: :: .: CCDS14 -GQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGC--TAHD 520 530 540 550 560 570 120 130 140 150 160 170 pF1KE4 CD-IAGLLKQFFRELPEPILPADLHEALLKAQQL-GTEEKNKAILLLSCLLADHTVHVLR : .::.:: .:: : :..: :: :: ...: .: :. . . : : .. ::: CCDS14 LDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLR 580 590 600 610 620 630 180 190 200 210 220 230 pF1KE4 YFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKKGVYQTLSWKRYQ :.:.:: ... :.:: :: :::: :.:.:: . :.. .. ... . . ::: CCDS14 YLFTFLNHLAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDR 640 650 660 670 680 690 240 250 260 pF1KE4 PCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV CCDS14 VFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNEPELEAEMPAQEDDLEGVVEAVA 700 710 720 730 740 750 >>CCDS55540.1 ARHGAP4 gene_id:393|Hs109|chrX (986 aa) initn: 152 init1: 152 opt: 292 Z-score: 359.7 bits: 76.1 E(33420): 1.1e-13 Smith-Waterman score: 292; 30.4% identity (62.3% similar) in 204 aa overlap (32-226:530-727) 10 20 30 40 50 60 pF1KE4 WDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVPE . :. ... . ..:: .. . .:. CCDS55 KHEKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSS--- 500 510 520 530 540 550 70 80 90 100 110 pF1KE4 YGHIPSFLVDACTSL--EEHIHTEGLFRKSGSVIRLKALKNKVDHGE-----GCLSSAPP :. ..:..: . . .. ::.:: ::. .:.. ... ..:: :: .: CCDS55 -GQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGC--TAHD 560 570 580 590 600 610 120 130 140 150 160 170 pF1KE4 CD-IAGLLKQFFRELPEPILPADLHEALLKAQQL-GTEEKNKAILLLSCLLADHTVHVLR : .::.:: .:: : :..: :: :: ...: .: :. . . : : .. ::: CCDS55 LDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLR 620 630 640 650 660 670 180 190 200 210 220 230 pF1KE4 YFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKKGVYQTLSWKRYQ :.:.:: ... :.:: :: :::: :.:.:: . :.. .. ... . . ::: CCDS55 YLFTFLNHLAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDR 680 690 700 710 720 730 240 250 260 pF1KE4 PCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV CCDS55 VFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNEPELEAEMPAQEDDLEGVVEAVA 740 750 760 770 780 790 >>CCDS58079.1 ARHGAP22 gene_id:58504|Hs109|chr10 (608 aa) initn: 271 init1: 106 opt: 288 Z-score: 358.1 bits: 75.2 E(33420): 1.3e-13 Smith-Waterman score: 288; 34.3% identity (66.9% similar) in 172 aa overlap (42-205:58-228) 20 30 40 50 60 70 pF1KE4 LQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVPEYG-HIPSFLV .:: ::: .. : .:: .. .:: CCDS58 ANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHER-KYGPRLAPLLV 30 40 50 60 70 80 80 90 100 110 120 pF1KE4 DACTSL--EEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCL--SSAPPCDIAGLLKQFFR . :... :. . ::::: :.. .. :... : :: : :.. .:.::: ..: CCDS58 EQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLR 90 100 110 120 130 140 130 140 150 160 170 180 pF1KE4 ELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLAD---HTVHVLRYFFNFLRNVSL :::::..: .: .:. :: :...... : :. ... . ..:::. .:: .:. CCDS58 ELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQA 150 160 170 180 190 200 190 200 210 220 230 240 pF1KE4 RSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLL :. :::. .:::..:.::.:. CCDS58 YSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEG 210 220 230 240 250 260 >>CCDS7227.1 ARHGAP22 gene_id:58504|Hs109|chr10 (698 aa) initn: 271 init1: 106 opt: 288 Z-score: 357.1 bits: 75.2 E(33420): 1.5e-13 Smith-Waterman score: 288; 34.3% identity (66.9% similar) in 172 aa overlap (42-205:148-318) 20 30 40 50 60 70 pF1KE4 LQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVPEYG-HIPSFLV .:: ::: .. : .:: .. .:: CCDS72 ANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHER-KYGPRLAPLLV 120 130 140 150 160 170 80 90 100 110 120 pF1KE4 DACTSL--EEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCL--SSAPPCDIAGLLKQFFR . :... :. . ::::: :.. .. :... : :: : :.. .:.::: ..: CCDS72 EQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLR 180 190 200 210 220 230 130 140 150 160 170 180 pF1KE4 ELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLAD---HTVHVLRYFFNFLRNVSL :::::..: .: .:. :: :...... : :. ... . ..:::. .:: .:. CCDS72 ELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQA 240 250 260 270 280 290 190 200 210 220 230 240 pF1KE4 RSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLL :. :::. .:::..:.::.:. CCDS72 YSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEG 300 310 320 330 340 350 267 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Jul 16 15:58:36 2019 done: Tue Jul 16 15:58:36 2019 Total Scan time: 1.050 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]