Result of FASTA (omim) for
pF1KE4189
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4189, 675 aa
1>>>pF1KE4189 675 - 675 aa - 675 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4048+/-0.000419; mu= 14.8048+/- 0.026
mean_var=132.1105+/-27.089, 0's: 0 Z-trim(115.6): 394 B-trim: 803 in 1/50
Lambda= 0.111585
statistics sampled from 26751 (27258) to 26751 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.295), width: 16
Scan time: 5.770
The best scores are: opt bits E(92320)
NP_001305256 (OMIM: 611282,618415) dynamin-binding ( 865) 719 128.1 1.4e-28
NP_001305255 (OMIM: 611282,618415) dynamin-binding (1209) 719 128.3 1.8e-28
NP_056036 (OMIM: 611282,618415) dynamin-binding pr (1577) 719 128.4 2.2e-28
XP_011537861 (OMIM: 611282,618415) dynamin-binding (1577) 719 128.4 2.2e-28
XP_006717798 (OMIM: 611282,618415) dynamin-binding (1534) 556 102.1 1.7e-20
NP_065871 (OMIM: 606905) phosphatidylinositol 3,4, (1659) 338 67.1 6.7e-10
NP_001273724 (OMIM: 613324) spermatogenesis-associ ( 574) 301 60.7 1.9e-08
NP_001273723 (OMIM: 613324) spermatogenesis-associ ( 596) 301 60.7 2e-08
NP_694568 (OMIM: 613324) spermatogenesis-associate ( 652) 301 60.7 2.1e-08
NP_001159743 (OMIM: 613324) spermatogenesis-associ (1277) 301 61.0 3.4e-08
NP_001273721 (OMIM: 613324) spermatogenesis-associ (1339) 301 61.0 3.5e-08
XP_011509579 (OMIM: 605216) rho guanine nucleotide ( 483) 293 59.3 4.2e-08
XP_011509578 (OMIM: 605216) rho guanine nucleotide ( 483) 293 59.3 4.2e-08
XP_024308706 (OMIM: 605216) rho guanine nucleotide ( 483) 293 59.3 4.2e-08
XP_005263746 (OMIM: 605216) rho guanine nucleotide ( 483) 293 59.3 4.2e-08
XP_005263745 (OMIM: 605216) rho guanine nucleotide ( 483) 293 59.3 4.2e-08
XP_005263744 (OMIM: 605216) rho guanine nucleotide ( 567) 293 59.4 4.7e-08
NP_056135 (OMIM: 605216) rho guanine nucleotide ex ( 690) 293 59.5 5.4e-08
XP_016884869 (OMIM: 300429,300607) rho guanine nuc ( 305) 284 57.7 8.2e-08
NP_001355972 (OMIM: 300429,300607) rho guanine nuc ( 344) 284 57.7 9e-08
NP_001355973 (OMIM: 300429,300607) rho guanine nuc ( 344) 284 57.7 9e-08
XP_016884863 (OMIM: 300429,300607) rho guanine nuc ( 412) 285 58.0 9.1e-08
XP_016884867 (OMIM: 300429,300607) rho guanine nuc ( 362) 284 57.8 9.3e-08
XP_016884866 (OMIM: 300429,300607) rho guanine nuc ( 365) 284 57.8 9.3e-08
NP_001355970 (OMIM: 300429,300607) rho guanine nuc ( 451) 285 58.0 9.7e-08
NP_001340856 (OMIM: 300429,300607) rho guanine nuc ( 451) 285 58.0 9.7e-08
NP_001340857 (OMIM: 300429,300607) rho guanine nuc ( 472) 285 58.0 1e-07
NP_001340851 (OMIM: 300429,300607) rho guanine nuc ( 479) 285 58.0 1e-07
NP_001355968 (OMIM: 300429,300607) rho guanine nuc ( 456) 284 57.8 1.1e-07
NP_001355969 (OMIM: 300429,300607) rho guanine nuc ( 456) 284 57.8 1.1e-07
NP_001340853 (OMIM: 300429,300607) rho guanine nuc ( 456) 284 57.8 1.1e-07
NP_001340855 (OMIM: 300429,300607) rho guanine nuc ( 456) 284 57.8 1.1e-07
NP_001166950 (OMIM: 300429,300607) rho guanine nuc ( 463) 284 57.9 1.1e-07
NP_001317424 (OMIM: 300429,300607) rho guanine nuc ( 495) 284 57.9 1.2e-07
NP_001355962 (OMIM: 300429,300607) rho guanine nuc ( 495) 284 57.9 1.2e-07
NP_001355966 (OMIM: 300429,300607) rho guanine nuc ( 495) 284 57.9 1.2e-07
NP_001355963 (OMIM: 300429,300607) rho guanine nuc ( 495) 284 57.9 1.2e-07
NP_001355965 (OMIM: 300429,300607) rho guanine nuc ( 495) 284 57.9 1.2e-07
NP_001355967 (OMIM: 300429,300607) rho guanine nuc ( 495) 284 57.9 1.2e-07
XP_024308125 (OMIM: 300429,300607) rho guanine nuc ( 495) 284 57.9 1.2e-07
NP_001355964 (OMIM: 300429,300607) rho guanine nuc ( 495) 284 57.9 1.2e-07
XP_024308124 (OMIM: 300429,300607) rho guanine nuc ( 514) 284 57.9 1.2e-07
NP_056000 (OMIM: 300429,300607) rho guanine nucleo ( 516) 284 57.9 1.2e-07
NP_001355960 (OMIM: 300429,300607) rho guanine nuc ( 516) 284 57.9 1.2e-07
NP_001355959 (OMIM: 300429,300607) rho guanine nuc ( 516) 284 57.9 1.2e-07
NP_001355961 (OMIM: 300429,300607) rho guanine nuc ( 516) 284 57.9 1.2e-07
XP_016884853 (OMIM: 300429,300607) rho guanine nuc ( 521) 284 57.9 1.2e-07
NP_001340850 (OMIM: 300429,300607) rho guanine nuc ( 523) 284 57.9 1.2e-07
NP_001340852 (OMIM: 300429,300607) rho guanine nuc ( 529) 284 57.9 1.2e-07
NP_001166951 (OMIM: 300429,300607) rho guanine nuc ( 414) 274 56.2 3.1e-07
>>NP_001305256 (OMIM: 611282,618415) dynamin-binding pro (865 aa)
initn: 942 init1: 281 opt: 719 Z-score: 634.5 bits: 128.1 E(92320): 1.4e-28
Smith-Waterman score: 869; 30.3% identity (63.8% similar) in 591 aa overlap (13-568:57-635)
10 20 30 40
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLLHQRLAVRELIDTE
::: . :. :.: : .. ...::..::
NP_001 PSGPHLHTQPALGTAEMTLLSSQSSSLVAPSGSVSAEN--PEQRMLEKRAKVIEELLQTE
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE4 VSYLHMLQLCASDIRSRLQQ--LPQGDLDVLFSNIDDIIKVNSRFLHDLQETASKEEEQV
.:.. :..: : .:: .:. :.. ::.:.. .:::....: : :
NP_001 RDYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAAL--------EIS
90 100 110 120 130
110 120 130 140 150
pF1KE4 QLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIV---EAVVPQAG
. :: .:: ..::: .::.:: ..:.:. :.. :.:. ..:.:.: . ... . :
NP_001 DAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE4 SSG---LSFLLVIPLQRITRYPLLLQKILENTVPDASAYPV-LQRAVSALQDVNTNINEY
.. :. .:. :.::. ::::::...: :..:.. : : :: :....:.:::::
NP_001 CTNYINLGSFLIKPVQRVMRYPLLLMELL-NSTPESHPDKVPLTNAVLAVKEINVNINEY
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE4 KMRKEVASKYTKVEQLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKEFDDLE
: ::... :: : .. .: :.....: :.. ::..:.:. ::. .:. :. .:. :.. :
NP_001 KRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETE
260 270 280 290 300 310
280 290 300 310 320
pF1KE4 ERFQWVSLCVTELKNNVAAYLDNLQAFLYFRP----HEYNLDIPEG--PAVQYCNLARDL
. :. . . ... ::.... . ... . .: :. . : .
NP_001 KNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMERGHRDLEQFERVHRYI
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE4 HLEAFLKFKQRLEGLVWQPLCSLAKALLGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYQ
. : .::.: : :: .:: .: . . ::..:..::.:::::: :. .. .
NP_001 SDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTL
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE4 EE--AARHTYQALNSLLVAELPQFNQLVMQWLGQIMCTFVTLQRDLAKQVLQRAEGSMAQ
:: .::..:.:::. :. :::.:.: .. . . . .. . :...:.:.. . ..
NP_001 EELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSL
440 450 460 470 480 490
450 460 470 480 490
pF1KE4 LPHHHVPEPAFRKLVEDALGRTSNQLRSF----------QETFEKV----QPPPTTQLLL
: : . . .. .:. .::. : .. ::. : : :
NP_001 LKVAGR-EGNLIAIFHEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSARKPLLGL
500 510 520 530 540 550
500 510 520 530 540
pF1KE4 PG----SERQVQALLSRYGPGKLYQVTSNISGTGTLDLTLPRGQIVAILQNKDTKGNSGR
:. ::. .::.:: : ::.:. :.... ::..: .:..:.....:: :...:
NP_001 PSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNR
560 570 580 590 600 610
550 560 570 580 590 600
pF1KE4 WLVDTGGHRGYVPAGKLQLYHVVPSAEELRRQAGLNKDPRCLTPEPSPALVPSIPTMNQV
::.:.: .:.: .. :. :.
NP_001 WLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFN
620 630 640 650 660 670
>>NP_001305255 (OMIM: 611282,618415) dynamin-binding pro (1209 aa)
initn: 942 init1: 281 opt: 719 Z-score: 632.6 bits: 128.3 E(92320): 1.8e-28
Smith-Waterman score: 869; 30.3% identity (63.8% similar) in 591 aa overlap (13-568:401-979)
10 20 30 40
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLLHQRLAVRELIDTE
::: . :. :.: : .. ...::..::
NP_001 TLRRSEFVQNSKKTQEMTLLSSQSSSLVAPSGSVSAEN--PEQRMLEKRAKVIEELLQTE
380 390 400 410 420
50 60 70 80 90 100
pF1KE4 VSYLHMLQLCASDIRSRLQQ--LPQGDLDVLFSNIDDIIKVNSRFLHDLQETASKEEEQV
.:.. :..: : .:: .:. :.. ::.:.. .:::....: : :
NP_001 RDYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAAL--------EIS
430 440 450 460 470 480
110 120 130 140 150
pF1KE4 QLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIV---EAVVPQAG
. :: .:: ..::: .::.:: ..:.:. :.. :.:. ..:.:.: . ... . :
NP_001 DAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWG
490 500 510 520 530 540
160 170 180 190 200 210
pF1KE4 SSG---LSFLLVIPLQRITRYPLLLQKILENTVPDASAYPV-LQRAVSALQDVNTNINEY
.. :. .:. :.::. ::::::...: :..:.. : : :: :....:.:::::
NP_001 CTNYINLGSFLIKPVQRVMRYPLLLMELL-NSTPESHPDKVPLTNAVLAVKEINVNINEY
550 560 570 580 590
220 230 240 250 260 270
pF1KE4 KMRKEVASKYTKVEQLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKEFDDLE
: ::... :: : .. .: :.....: :.. ::..:.:. ::. .:. :. .:. :.. :
NP_001 KRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETE
600 610 620 630 640 650
280 290 300 310 320
pF1KE4 ERFQWVSLCVTELKNNVAAYLDNLQAFLYFRP----HEYNLDIPEG--PAVQYCNLARDL
. :. . . ... ::.... . ... . .: :. . : .
NP_001 KNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMERGHRDLEQFERVHRYI
660 670 680 690 700 710
330 340 350 360 370 380
pF1KE4 HLEAFLKFKQRLEGLVWQPLCSLAKALLGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYQ
. : .::.: : :: .:: .: . . ::..:..::.:::::: :. .. .
NP_001 SDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTL
720 730 740 750 760 770
390 400 410 420 430 440
pF1KE4 EE--AARHTYQALNSLLVAELPQFNQLVMQWLGQIMCTFVTLQRDLAKQVLQRAEGSMAQ
:: .::..:.:::. :. :::.:.: .. . . . .. . :...:.:.. . ..
NP_001 EELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSL
780 790 800 810 820 830
450 460 470 480 490
pF1KE4 LPHHHVPEPAFRKLVEDALGRTSNQLRSF----------QETFEKV----QPPPTTQLLL
: : . . .. .:. .::. : .. ::. : : :
NP_001 LKVAGR-EGNLIAIFHEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSARKPLLGL
840 850 860 870 880 890
500 510 520 530 540
pF1KE4 PG----SERQVQALLSRYGPGKLYQVTSNISGTGTLDLTLPRGQIVAILQNKDTKGNSGR
:. ::. .::.:: : ::.:. :.... ::..: .:..:.....:: :...:
NP_001 PSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNR
900 910 920 930 940 950
550 560 570 580 590 600
pF1KE4 WLVDTGGHRGYVPAGKLQLYHVVPSAEELRRQAGLNKDPRCLTPEPSPALVPSIPTMNQV
::.:.: .:.: .. :. :.
NP_001 WLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFN
960 970 980 990 1000 1010
>>NP_056036 (OMIM: 611282,618415) dynamin-binding protei (1577 aa)
initn: 942 init1: 281 opt: 719 Z-score: 631.1 bits: 128.4 E(92320): 2.2e-28
Smith-Waterman score: 869; 30.3% identity (63.8% similar) in 591 aa overlap (13-568:769-1347)
10 20 30 40
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLLHQRLAVRELIDTE
::: . :. :.: : .. ...::..::
NP_056 ESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVSAEN--PEQRMLEKRAKVIEELLQTE
740 750 760 770 780 790
50 60 70 80 90 100
pF1KE4 VSYLHMLQLCASDIRSRLQQ--LPQGDLDVLFSNIDDIIKVNSRFLHDLQETASKEEEQV
.:.. :..: : .:: .:. :.. ::.:.. .:::....: : :
NP_056 RDYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAAL--------EIS
800 810 820 830 840
110 120 130 140 150
pF1KE4 QLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIV---EAVVPQAG
. :: .:: ..::: .::.:: ..:.:. :.. :.:. ..:.:.: . ... . :
NP_056 DAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWG
850 860 870 880 890 900
160 170 180 190 200 210
pF1KE4 SSG---LSFLLVIPLQRITRYPLLLQKILENTVPDASAYPV-LQRAVSALQDVNTNINEY
.. :. .:. :.::. ::::::...: :..:.. : : :: :....:.:::::
NP_056 CTNYINLGSFLIKPVQRVMRYPLLLMELL-NSTPESHPDKVPLTNAVLAVKEINVNINEY
910 920 930 940 950 960
220 230 240 250 260 270
pF1KE4 KMRKEVASKYTKVEQLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKEFDDLE
: ::... :: : .. .: :.....: :.. ::..:.:. ::. .:. :. .:. :.. :
NP_056 KRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETE
970 980 990 1000 1010 1020
280 290 300 310 320
pF1KE4 ERFQWVSLCVTELKNNVAAYLDNLQAFLYFRP----HEYNLDIPEG--PAVQYCNLARDL
. :. . . ... ::.... . ... . .: :. . : .
NP_056 KNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMERGHRDLEQFERVHRYI
1030 1040 1050 1060 1070 1080
330 340 350 360 370 380
pF1KE4 HLEAFLKFKQRLEGLVWQPLCSLAKALLGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYQ
. : .::.: : :: .:: .: . . ::..:..::.:::::: :. .. .
NP_056 SDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTL
1090 1100 1110 1120 1130 1140
390 400 410 420 430 440
pF1KE4 EE--AARHTYQALNSLLVAELPQFNQLVMQWLGQIMCTFVTLQRDLAKQVLQRAEGSMAQ
:: .::..:.:::. :. :::.:.: .. . . . .. . :...:.:.. . ..
NP_056 EELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSL
1150 1160 1170 1180 1190 1200
450 460 470 480 490
pF1KE4 LPHHHVPEPAFRKLVEDALGRTSNQLRSF----------QETFEKV----QPPPTTQLLL
: : . . .. .:. .::. : .. ::. : : :
NP_056 LKVAGR-EGNLIAIFHEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSARKPLLGL
1210 1220 1230 1240 1250 1260
500 510 520 530 540
pF1KE4 PG----SERQVQALLSRYGPGKLYQVTSNISGTGTLDLTLPRGQIVAILQNKDTKGNSGR
:. ::. .::.:: : ::.:. :.... ::..: .:..:.....:: :...:
NP_056 PSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNR
1270 1280 1290 1300 1310 1320
550 560 570 580 590 600
pF1KE4 WLVDTGGHRGYVPAGKLQLYHVVPSAEELRRQAGLNKDPRCLTPEPSPALVPSIPTMNQV
::.:.: .:.: .. :. :.
NP_056 WLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFN
1330 1340 1350 1360 1370 1380
>>XP_011537861 (OMIM: 611282,618415) dynamin-binding pro (1577 aa)
initn: 942 init1: 281 opt: 719 Z-score: 631.1 bits: 128.4 E(92320): 2.2e-28
Smith-Waterman score: 869; 30.3% identity (63.8% similar) in 591 aa overlap (13-568:769-1347)
10 20 30 40
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLLHQRLAVRELIDTE
::: . :. :.: : .. ...::..::
XP_011 ESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVSAEN--PEQRMLEKRAKVIEELLQTE
740 750 760 770 780 790
50 60 70 80 90 100
pF1KE4 VSYLHMLQLCASDIRSRLQQ--LPQGDLDVLFSNIDDIIKVNSRFLHDLQETASKEEEQV
.:.. :..: : .:: .:. :.. ::.:.. .:::....: : :
XP_011 RDYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAAL--------EIS
800 810 820 830 840
110 120 130 140 150
pF1KE4 QLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIV---EAVVPQAG
. :: .:: ..::: .::.:: ..:.:. :.. :.:. ..:.:.: . ... . :
XP_011 DAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWG
850 860 870 880 890 900
160 170 180 190 200 210
pF1KE4 SSG---LSFLLVIPLQRITRYPLLLQKILENTVPDASAYPV-LQRAVSALQDVNTNINEY
.. :. .:. :.::. ::::::...: :..:.. : : :: :....:.:::::
XP_011 CTNYINLGSFLIKPVQRVMRYPLLLMELL-NSTPESHPDKVPLTNAVLAVKEINVNINEY
910 920 930 940 950 960
220 230 240 250 260 270
pF1KE4 KMRKEVASKYTKVEQLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKEFDDLE
: ::... :: : .. .: :.....: :.. ::..:.:. ::. .:. :. .:. :.. :
XP_011 KRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETE
970 980 990 1000 1010 1020
280 290 300 310 320
pF1KE4 ERFQWVSLCVTELKNNVAAYLDNLQAFLYFRP----HEYNLDIPEG--PAVQYCNLARDL
. :. . . ... ::.... . ... . .: :. . : .
XP_011 KNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMERGHRDLEQFERVHRYI
1030 1040 1050 1060 1070 1080
330 340 350 360 370 380
pF1KE4 HLEAFLKFKQRLEGLVWQPLCSLAKALLGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYQ
. : .::.: : :: .:: .: . . ::..:..::.:::::: :. .. .
XP_011 SDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTL
1090 1100 1110 1120 1130 1140
390 400 410 420 430 440
pF1KE4 EE--AARHTYQALNSLLVAELPQFNQLVMQWLGQIMCTFVTLQRDLAKQVLQRAEGSMAQ
:: .::..:.:::. :. :::.:.: .. . . . .. . :...:.:.. . ..
XP_011 EELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSL
1150 1160 1170 1180 1190 1200
450 460 470 480 490
pF1KE4 LPHHHVPEPAFRKLVEDALGRTSNQLRSF----------QETFEKV----QPPPTTQLLL
: : . . .. .:. .::. : .. ::. : : :
XP_011 LKVAGR-EGNLIAIFHEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSARKPLLGL
1210 1220 1230 1240 1250 1260
500 510 520 530 540
pF1KE4 PG----SERQVQALLSRYGPGKLYQVTSNISGTGTLDLTLPRGQIVAILQNKDTKGNSGR
:. ::. .::.:: : ::.:. :.... ::..: .:..:.....:: :...:
XP_011 PSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNR
1270 1280 1290 1300 1310 1320
550 560 570 580 590 600
pF1KE4 WLVDTGGHRGYVPAGKLQLYHVVPSAEELRRQAGLNKDPRCLTPEPSPALVPSIPTMNQV
::.:.: .:.: .. :. :.
XP_011 WLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFN
1330 1340 1350 1360 1370 1380
>>XP_006717798 (OMIM: 611282,618415) dynamin-binding pro (1534 aa)
initn: 814 init1: 281 opt: 556 Z-score: 489.5 bits: 102.1 E(92320): 1.7e-20
Smith-Waterman score: 804; 29.7% identity (61.7% similar) in 585 aa overlap (13-568:769-1304)
10 20 30 40
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLLHQRLAVRELIDTE
::: . :. :.: : .. ...::..::
XP_006 ESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVSAEN--PEQRMLEKRAKVIEELLQTE
740 750 760 770 780 790
50 60 70 80 90 100
pF1KE4 VSYLHMLQLCASDIRSRLQQ--LPQGDLDVLFSNIDDIIKVNSRFLHDLQETASKEEEQV
.:.. :..: : .:: .:. :.. ::.:.. .:::....: : :
XP_006 RDYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAAL--------EIS
800 810 820 830 840
110 120 130 140 150
pF1KE4 QLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIV---EAVVPQAG
. :: .:: ..::: .::.:: ..:.:. :.. :.:. ..:.:.: . ... . :
XP_006 DAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWG
850 860 870 880 890 900
160 170 180 190 200 210
pF1KE4 SSG---LSFLLVIPLQRITRYPLLLQKILENTVPDASAYPV-LQRAVSALQDVNTNINEY
.. :. .:. :.::. ::::::...: :..:.. : : :: :....:.:::::
XP_006 CTNYINLGSFLIKPVQRVMRYPLLLMELL-NSTPESHPDKVPLTNAVLAVKEINVNINEY
910 920 930 940 950 960
220 230 240 250 260 270
pF1KE4 KMRKEVASKYTKVEQLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKEFDDLE
: ::... :: : .. .: :.....: :.. ::..:.:. ::. .:. :. .:. :.. :
XP_006 KRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETE
970 980 990 1000 1010 1020
280 290 300 310 320 330
pF1KE4 ERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEGPAVQYCNLARDLHLEAFL
. :. . . ... ::....
XP_006 KNFRMQERLIKSFIRDLSLYLQHIR-----------------------------------
1030 1040 1050
340 350 360 370 380 390
pF1KE4 KFKQRLEGLVWQPLCSLAKALLGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYQEE--AA
:.: : :: .:: .: . . ::..:..::.:::::: :. .. . :: .:
XP_006 --KERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSA
1060 1070 1080 1090 1100 1110
400 410 420 430 440 450
pF1KE4 RHTYQALNSLLVAELPQFNQLVMQWLGQIMCTFVTLQRDLAKQVLQRAEGSMAQLPHHHV
:..:.:::. :. :::.:.: .. . . . .. . :...:.:.. . .. :
XP_006 RNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSLLKVAGR
1120 1130 1140 1150 1160 1170
460 470 480 490
pF1KE4 PEPAFRKLVEDALGRTSNQLRSF----------QETFEKV----QPPPTTQLLLPG----
: . . .. .:. .::. : .. ::. : : ::.
XP_006 -EGNLIAIFHEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSARKPLLGLPSYMLQ
1180 1190 1200 1210 1220
500 510 520 530 540 550
pF1KE4 SERQVQALLSRYGPGKLYQVTSNISGTGTLDLTLPRGQIVAILQNKDTKGNSGRWLVDTG
::. .::.:: : ::.:. :.... ::..: .:..:.....:: :...:::.:.:
XP_006 SEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLIDNG
1230 1240 1250 1260 1270 1280
560 570 580 590 600 610
pF1KE4 GHRGYVPAGKLQLYHVVPSAEELRRQAGLNKDPRCLTPEPSPALVPSIPTMNQVIAAYPF
.:.: .. :. :.
XP_006 VTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFNPSSMAV
1290 1300 1310 1320 1330 1340
>>NP_065871 (OMIM: 606905) phosphatidylinositol 3,4,5-tr (1659 aa)
initn: 311 init1: 170 opt: 338 Z-score: 299.4 bits: 67.1 E(92320): 6.7e-10
Smith-Waterman score: 339; 31.5% identity (56.3% similar) in 279 aa overlap (5-272:26-297)
10 20 30
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLLHQRLAV-REL
:: ::: : : .: :: . :. :: : :.
NP_065 MEAPSGSEPGGDGAGDCAHPDPRAPGAAAPSSGPG-PCAAARESERQ--LRLRLCVLNEI
10 20 30 40 50
40 50 60 70 80
pF1KE4 IDTEVSYLHMLQLCASDIRSRLQQ---------LPQGDLDVLFSNIDDIIKVNSRFLHDL
. :: .:. :.. : . :..: : . .. ::::::.::..:.. :: :
NP_065 LGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAAL
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE4 QETASKEEEQVQLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIV
. : .. . .::.::.:.... ::. ::.....:: :. : : .. . . .
NP_065 EYCLHPEPQSQHELGNVFLKFKDKFC-VYEEYCSNHEKALRLLVELNKIPTVRAFLLSCM
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE4 EAVVPQAGSSGLSFLLVIPLQRITRYPLLLQKILENTVPDASAYPVLQRAVSALQDVNTN
.. . : :. :.::: .:::::... . : .:..: :..:.. : .:
NP_065 LLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCSN
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE4 INEYKMRKEVASKYTKVEQLTLR-ERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKE
::: : . : : .::: . : : . . . ::: :: : .
NP_065 INETKRQME---KLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFL
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE4 FDDLEERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEGPAVQYCNLARDLH
::.:
NP_065 FDNLLVYCKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGY
300 310 320 330 340 350
>>NP_001273724 (OMIM: 613324) spermatogenesis-associated (574 aa)
initn: 150 init1: 124 opt: 301 Z-score: 273.1 bits: 60.7 E(92320): 1.9e-08
Smith-Waterman score: 304; 27.9% identity (62.2% similar) in 262 aa overlap (8-256:134-390)
10 20 30
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLL---HQRL-
: :: . : ... .::..: .:..
NP_001 KDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMR
110 120 130 140 150 160
40 50 60 70 80
pF1KE4 --AVRELIDTEVSYL-HMLQLCASDIRS---RLQQLPQGDLDVLFSNIDDIIKVNSRFLH
..::..::: :. :. ..: . ::. . .. ..: ..:.::.:: : . .::.
NP_001 TNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLK
170 180 190 200 210 220
90 100 110 120 130 140
pF1KE4 DLQETASKEEEQVQLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQG
::.. .::: ... .:. ::. :: . .:. :: .. : : . . :. . ::.
NP_001 DLEKQYNKEEPHLSEIGSCFLQNQEGFA-IYSEYCNNHPGACLELANLMKQGKY-RHF--
230 240 250 260 270
150 160 170 180 190 200
pF1KE4 IVEA--VVPQAGSSGLSFLLVIPLQRITRYPLLLQKILENTVPDASAYPVLQRAVSALQD
:: .. : . ... .:. :.:.: .::: : ..:. :. . . : .. : :...
NP_001 -FEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKN
280 290 300 310 320 330
210 220 230 240 250 260
pF1KE4 VNTNINEYKMRKEVASKYTKVE-QLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRT
: ::: : . : .: .. . ... : : .. . .. .:... ::
NP_001 VACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTF
340 350 360 370 380 390
270 280 290 300 310 320
pF1KE4 EDKEFDDLEERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEGPAVQYCNLA
NP_001 FLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTD
400 410 420 430 440 450
>>NP_001273723 (OMIM: 613324) spermatogenesis-associated (596 aa)
initn: 150 init1: 124 opt: 301 Z-score: 272.9 bits: 60.7 E(92320): 2e-08
Smith-Waterman score: 304; 27.9% identity (62.2% similar) in 262 aa overlap (8-256:156-412)
10 20 30
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLL---HQRL-
: :: . : ... .::..: .:..
NP_001 KDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMR
130 140 150 160 170 180
40 50 60 70 80
pF1KE4 --AVRELIDTEVSYL-HMLQLCASDIRS---RLQQLPQGDLDVLFSNIDDIIKVNSRFLH
..::..::: :. :. ..: . ::. . .. ..: ..:.::.:: : . .::.
NP_001 TNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLK
190 200 210 220 230 240
90 100 110 120 130 140
pF1KE4 DLQETASKEEEQVQLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQG
::.. .::: ... .:. ::. :: . .:. :: .. : : . . :. . ::.
NP_001 DLEKQYNKEEPHLSEIGSCFLQNQEGFA-IYSEYCNNHPGACLELANLMKQGKY-RHF--
250 260 270 280 290 300
150 160 170 180 190 200
pF1KE4 IVEA--VVPQAGSSGLSFLLVIPLQRITRYPLLLQKILENTVPDASAYPVLQRAVSALQD
:: .. : . ... .:. :.:.: .::: : ..:. :. . . : .. : :...
NP_001 -FEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKN
310 320 330 340 350 360
210 220 230 240 250 260
pF1KE4 VNTNINEYKMRKEVASKYTKVE-QLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRT
: ::: : . : .: .. . ... : : .. . .. .:... ::
NP_001 VACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTF
370 380 390 400 410 420
270 280 290 300 310 320
pF1KE4 EDKEFDDLEERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEGPAVQYCNLA
NP_001 FLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTD
430 440 450 460 470 480
>>NP_694568 (OMIM: 613324) spermatogenesis-associated pr (652 aa)
initn: 150 init1: 124 opt: 301 Z-score: 272.4 bits: 60.7 E(92320): 2.1e-08
Smith-Waterman score: 304; 27.9% identity (62.2% similar) in 262 aa overlap (8-256:212-468)
10 20 30
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLL---HQRL-
: :: . : ... .::..: .:..
NP_694 KDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMR
190 200 210 220 230 240
40 50 60 70 80
pF1KE4 --AVRELIDTEVSYL-HMLQLCASDIRS---RLQQLPQGDLDVLFSNIDDIIKVNSRFLH
..::..::: :. :. ..: . ::. . .. ..: ..:.::.:: : . .::.
NP_694 TNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLK
250 260 270 280 290 300
90 100 110 120 130 140
pF1KE4 DLQETASKEEEQVQLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQG
::.. .::: ... .:. ::. :: . .:. :: .. : : . . :. . ::.
NP_694 DLEKQYNKEEPHLSEIGSCFLQNQEGFA-IYSEYCNNHPGACLELANLMKQGKY-RHF--
310 320 330 340 350
150 160 170 180 190 200
pF1KE4 IVEA--VVPQAGSSGLSFLLVIPLQRITRYPLLLQKILENTVPDASAYPVLQRAVSALQD
:: .. : . ... .:. :.:.: .::: : ..:. :. . . : .. : :...
NP_694 -FEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKN
360 370 380 390 400 410
210 220 230 240 250 260
pF1KE4 VNTNINEYKMRKEVASKYTKVE-QLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRT
: ::: : . : .: .. . ... : : .. . .. .:... ::
NP_694 VACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTF
420 430 440 450 460 470
270 280 290 300 310 320
pF1KE4 EDKEFDDLEERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEGPAVQYCNLA
NP_694 FLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTD
480 490 500 510 520 530
>>NP_001159743 (OMIM: 613324) spermatogenesis-associated (1277 aa)
initn: 124 init1: 124 opt: 301 Z-score: 268.7 bits: 61.0 E(92320): 3.4e-08
Smith-Waterman score: 304; 27.9% identity (62.2% similar) in 262 aa overlap (8-256:837-1093)
10 20 30
pF1KE4 MAKHGADEPSSRSGSPDREGRASEDRSLL---HQRL-
: :: . : ... .::..: .:..
NP_001 KDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMR
810 820 830 840 850 860
40 50 60 70 80
pF1KE4 --AVRELIDTEVSYL-HMLQLCASDIRS---RLQQLPQGDLDVLFSNIDDIIKVNSRFLH
..::..::: :. :. ..: . ::. . .. ..: ..:.::.:: : . .::.
NP_001 TNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLK
870 880 890 900 910 920
90 100 110 120 130 140
pF1KE4 DLQETASKEEEQVQLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQG
::.. .::: ... .:. ::. :: . .:. :: .. : : . . :. . ::.
NP_001 DLEKQYNKEEPHLSEIGSCFLQNQEGFA-IYSEYCNNHPGACLELANLMKQGKY-RHF--
930 940 950 960 970 980
150 160 170 180 190 200
pF1KE4 IVEA--VVPQAGSSGLSFLLVIPLQRITRYPLLLQKILENTVPDASAYPVLQRAVSALQD
:: .. : . ... .:. :.:.: .::: : ..:. :. . . : .. : :...
NP_001 -FEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKN
990 1000 1010 1020 1030 1040
210 220 230 240 250 260
pF1KE4 VNTNINEYKMRKEVASKYTKVE-QLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRT
: ::: : . : .: .. . ... : : .. . .. .:... ::
NP_001 VACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTF
1050 1060 1070 1080 1090 1100
270 280 290 300 310 320
pF1KE4 EDKEFDDLEERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEGPAVQYCNLA
NP_001 FLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTD
1110 1120 1130 1140 1150 1160
675 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:52:27 2019 done: Thu Oct 24 21:52:28 2019
Total Scan time: 5.770 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]