FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE4516, 550 aa 1>>>pF1KE4516 550 - 550 aa - 550 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8549+/-0.000413; mu= 22.1375+/- 0.026 mean_var=81.5101+/-16.523, 0's: 0 Z-trim(111.4): 221 B-trim: 1057 in 1/54 Lambda= 0.142059 statistics sampled from 19790 (20033) to 19790 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.235), width: 16 Scan time: 9.740 The best scores are: opt bits E(85289) NP_695008 (OMIM: 607582) solute carrier family 22 ( 550) 3666 761.7 0 XP_016874051 (OMIM: 607582) PREDICTED: solute carr ( 551) 3654 759.2 0 NP_004781 (OMIM: 607582) solute carrier family 22 ( 563) 3481 723.7 3.6e-208 NP_695009 (OMIM: 607582) solute carrier family 22 ( 506) 3057 636.8 4.8e-182 NP_695010 (OMIM: 607582) solute carrier family 22 ( 519) 3053 636.0 8.6e-182 NP_004245 (OMIM: 607581) solute carrier family 22 ( 542) 1655 349.5 1.6e-95 NP_001171661 (OMIM: 607581) solute carrier family ( 542) 1655 349.5 1.6e-95 NP_001171662 (OMIM: 607581) solute carrier family ( 451) 1592 336.5 1.1e-91 NP_060954 (OMIM: 607097) solute carrier family 22 ( 550) 1490 315.7 2.4e-85 NP_653186 (OMIM: 220150,607096) solute carrier fam ( 553) 1476 312.8 1.8e-84 XP_011543666 (OMIM: 607581) PREDICTED: solute carr ( 419) 1452 307.8 4.4e-83 NP_001171665 (OMIM: 607581) solute carrier family ( 419) 1452 307.8 4.4e-83 XP_016873188 (OMIM: 607580) PREDICTED: solute carr ( 489) 1306 277.9 5e-74 NP_001034841 (OMIM: 607580) solute carrier family ( 541) 1306 278.0 5.3e-74 XP_011543318 (OMIM: 607580) PREDICTED: solute carr ( 541) 1306 278.0 5.3e-74 NP_001129978 (OMIM: 611698) solute carrier family ( 552) 1306 278.0 5.4e-74 NP_006663 (OMIM: 604995) solute carrier family 22 ( 546) 1298 276.3 1.7e-73 NP_696961 (OMIM: 604995) solute carrier family 22 ( 548) 1284 273.5 1.2e-72 NP_543142 (OMIM: 607579) solute carrier family 22 ( 553) 1168 249.7 1.8e-65 NP_955384 (OMIM: 610792) solute carrier family 22 ( 547) 1158 247.6 7.3e-65 XP_016873176 (OMIM: 610792) PREDICTED: solute carr ( 547) 1158 247.6 7.3e-65 XP_006715034 (OMIM: 604995) PREDICTED: solute carr ( 549) 1138 243.5 1.3e-63 XP_006715033 (OMIM: 604995) PREDICTED: solute carr ( 551) 1043 224.1 9.1e-58 NP_004247 (OMIM: 604047) solute carrier family 22 ( 551) 1017 218.7 3.7e-56 XP_011543469 (OMIM: 607097) PREDICTED: solute carr ( 417) 1015 218.2 4e-56 XP_016873264 (OMIM: 611696) PREDICTED: solute carr ( 354) 982 211.4 3.9e-54 XP_011512559 (OMIM: 604995) PREDICTED: solute carr ( 607) 983 211.8 4.9e-54 XP_016873265 (OMIM: 611696) PREDICTED: solute carr ( 323) 969 208.7 2.3e-53 NP_700357 (OMIM: 220150,607096) solute carrier fam ( 332) 967 208.3 3.1e-53 NP_001263255 (OMIM: 220150,607096) solute carrier ( 519) 969 208.9 3.2e-53 XP_016865689 (OMIM: 604995) PREDICTED: solute carr ( 543) 967 208.5 4.4e-53 XP_006718494 (OMIM: 220150,607096) PREDICTED: solu ( 543) 967 208.5 4.4e-53 XP_006718493 (OMIM: 220150,607096) PREDICTED: solu ( 578) 967 208.5 4.6e-53 XP_011512558 (OMIM: 604995) PREDICTED: solute carr ( 610) 967 208.5 4.8e-53 NP_001294914 (OMIM: 607097) solute carrier family ( 442) 962 207.4 7.8e-53 XP_016865687 (OMIM: 604995) PREDICTED: solute carr ( 602) 960 207.1 1.3e-52 XP_011512563 (OMIM: 604995) PREDICTED: solute carr ( 420) 958 206.5 1.3e-52 XP_016865690 (OMIM: 604995) PREDICTED: solute carr ( 420) 958 206.5 1.3e-52 XP_016872648 (OMIM: 607579) PREDICTED: solute carr ( 445) 929 200.6 8.5e-51 XP_016873190 (OMIM: 607580) PREDICTED: solute carr ( 424) 908 196.3 1.6e-49 NP_068812 (OMIM: 604842) solute carrier family 22 ( 556) 898 194.4 8.1e-49 NP_003051 (OMIM: 212140,603377) solute carrier fam ( 557) 890 192.7 2.5e-48 NP_003049 (OMIM: 602608) solute carrier family 22 ( 555) 886 191.9 4.4e-48 NP_003048 (OMIM: 602607) solute carrier family 22 ( 554) 841 182.7 2.6e-45 XP_005267163 (OMIM: 604842) PREDICTED: solute carr ( 425) 838 181.9 3.4e-45 XP_016873191 (OMIM: 607580) PREDICTED: solute carr ( 365) 836 181.5 4e-45 XP_011534378 (OMIM: 604842) PREDICTED: solute carr ( 404) 812 176.6 1.3e-43 XP_016866692 (OMIM: 604842) PREDICTED: solute carr ( 404) 812 176.6 1.3e-43 XP_011534377 (OMIM: 604842) PREDICTED: solute carr ( 404) 812 176.6 1.3e-43 XP_016873192 (OMIM: 607580) PREDICTED: solute carr ( 331) 800 174.0 6.3e-43 >>NP_695008 (OMIM: 607582) solute carrier family 22 memb (550 aa) initn: 3666 init1: 3666 opt: 3666 Z-score: 4063.4 bits: 761.7 E(85289): 0 Smith-Waterman score: 3666; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550) 10 20 30 40 50 60 pF1KE4 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE4 QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE4 IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE4 LYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRKGKQTRQQQEHQKYMVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 LYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRKGKQTRQQQEHQKYMVPL 490 500 510 520 530 540 550 pF1KE4 QASAQEKNGL :::::::::: NP_695 QASAQEKNGL 550 >>XP_016874051 (OMIM: 607582) PREDICTED: solute carrier (551 aa) initn: 2119 init1: 2095 opt: 3654 Z-score: 4050.1 bits: 759.2 E(85289): 0 Smith-Waterman score: 3654; 99.8% identity (99.8% similar) in 551 aa overlap (1-550:1-551) 10 20 30 40 50 60 pF1KE4 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE 250 260 270 280 290 300 310 320 330 340 350 pF1KE4 GAKLSME-VLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMD ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAKLSMEQVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE4 LQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE4 SIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE4 ELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRKGKQTRQQQEHQKYMVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRKGKQTRQQQEHQKYMVP 490 500 510 520 530 540 540 550 pF1KE4 LQASAQEKNGL ::::::::::: XP_016 LQASAQEKNGL 550 >>NP_004781 (OMIM: 607582) solute carrier family 22 memb (563 aa) initn: 3481 init1: 3481 opt: 3481 Z-score: 3858.4 bits: 723.7 E(85289): 3.6e-208 Smith-Waterman score: 3630; 97.7% identity (97.7% similar) in 563 aa overlap (1-550:1-563) 10 20 30 40 50 60 pF1KE4 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE4 QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE4 IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAE 430 440 450 460 470 480 490 500 510 520 pF1KE4 LYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESR-------------KGKQT :::::::::::::::::::::::::::::::::::::::::: ::::: NP_004 LYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKGKQT 490 500 510 520 530 540 530 540 550 pF1KE4 RQQQEHQKYMVPLQASAQEKNGL ::::::::::::::::::::::: NP_004 RQQQEHQKYMVPLQASAQEKNGL 550 560 >>NP_695009 (OMIM: 607582) solute carrier family 22 memb (506 aa) initn: 3050 init1: 3050 opt: 3057 Z-score: 3389.3 bits: 636.8 E(85289): 4.8e-182 Smith-Waterman score: 3289; 92.0% identity (92.0% similar) in 550 aa overlap (1-550:1-506) 10 20 30 40 50 60 pF1KE4 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE4 QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE4 IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAE :::::::::::::::::::::::::::::::::: NP_695 IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIR-------------------------- 430 440 450 490 500 510 520 530 540 pF1KE4 LYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRKGKQTRQQQEHQKYMVPL :::::::::::::::::::::::::::::::::::::::::: NP_695 ------------------AVTVLLPETLGQPLPDTVQDLESRKGKQTRQQQEHQKYMVPL 460 470 480 490 550 pF1KE4 QASAQEKNGL :::::::::: NP_695 QASAQEKNGL 500 >>NP_695010 (OMIM: 607582) solute carrier family 22 memb (519 aa) initn: 3228 init1: 3050 opt: 3053 Z-score: 3384.7 bits: 636.0 E(85289): 8.6e-182 Smith-Waterman score: 3253; 89.9% identity (89.9% similar) in 563 aa overlap (1-550:1-519) 10 20 30 40 50 60 pF1KE4 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 GGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 VTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 FAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 AYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 GAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE4 QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_695 QGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE4 IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAE :::::::::::::::::::::::::::::::::: NP_695 IVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIR-------------------------- 430 440 450 490 500 510 520 pF1KE4 LYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESR-------------KGKQT :::::::::::::::::::::::: ::::: NP_695 ------------------AVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKGKQT 460 470 480 490 530 540 550 pF1KE4 RQQQEHQKYMVPLQASAQEKNGL ::::::::::::::::::::::: NP_695 RQQQEHQKYMVPLQASAQEKNGL 500 510 >>NP_004245 (OMIM: 607581) solute carrier family 22 memb (542 aa) initn: 1821 init1: 1513 opt: 1655 Z-score: 1836.0 bits: 349.5 E(85289): 1.6e-95 Smith-Waterman score: 1851; 50.8% identity (79.0% similar) in 547 aa overlap (1-541:1-533) 10 20 30 40 50 60 pF1KE4 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN :.:...:..::..:.:: ..:... ::.: ::.:: :: :::: :.:::::: .:. . NP_004 MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGP- 10 20 30 40 50 70 80 90 100 110 pF1KE4 GGLEVW-LPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTG-ATEPCTDGWIYDNSTFPS : :: .:.:: ::::. : : :.. : : : ::: :::.: ::: . NP_004 -----WVLPMGPNGKPERCLRFVHP----P--NASLPNDTQRAMEPCLDGWVY-NST-KD 60 70 80 90 100 120 130 140 150 160 170 pF1KE4 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC .:::::::::. :...:::..:.:.:.:..:.: :.::.::: .: .:: :.::. NP_004 SIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE4 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLA :::.:.:::: .::.: :....::.:. . :::::.: . :: ..: .:: :..:::.: NP_004 AAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILP 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE4 GVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKR :.:::.:.:: ::: :: :::.::. ::. :: :: ::. . .:. :.::: .:::. NP_004 GLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKK 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE4 EEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVM ::: .::.: :. .::::....:.. .: .:.: : ::.. .:::. ::::.::::.:.: NP_004 EEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAM 290 300 310 320 330 340 360 370 380 390 400 410 pF1KE4 DLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQD .. :::..:..:.:::.::.:::.. .: .. :::. .: ::::::: :: .: : NP_004 GVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLD 350 360 370 380 390 400 420 430 440 450 460 470 pF1KE4 QSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMT . ::: :::.:::::..::.:.::::.:::::.:::::::... .::::.:::::..: NP_004 LQTVRTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKIT 410 420 430 440 450 460 480 490 500 510 520 530 pF1KE4 AELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE--SRKGKQTRQQQEHQK- .:. : .: .::: . . .......:::::.::::.:..::: : ..:. .:. : .: NP_004 GEVQPFIPNIIYGITALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPEVEKA 470 480 490 500 510 520 540 550 pF1KE4 -YMVPLQASAQEKNGL .::: NP_004 SQRIPLQPHGPGLGSS 530 540 >>NP_001171661 (OMIM: 607581) solute carrier family 22 m (542 aa) initn: 1821 init1: 1513 opt: 1655 Z-score: 1836.0 bits: 349.5 E(85289): 1.6e-95 Smith-Waterman score: 1851; 50.8% identity (79.0% similar) in 547 aa overlap (1-541:1-533) 10 20 30 40 50 60 pF1KE4 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKN :.:...:..::..:.:: ..:... ::.: ::.:: :: :::: :.:::::: .:. . NP_001 MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGP- 10 20 30 40 50 70 80 90 100 110 pF1KE4 GGLEVW-LPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTG-ATEPCTDGWIYDNSTFPS : :: .:.:: ::::. : : :.. : : : ::: :::.: ::: . NP_001 -----WVLPMGPNGKPERCLRFVHP----P--NASLPNDTQRAMEPCLDGWVY-NST-KD 60 70 80 90 100 120 130 140 150 160 170 pF1KE4 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC .:::::::::. :...:::..:.:.:.:..:.: :.::.::: .: .:: :.::. NP_001 SIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE4 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLA :::.:.:::: .::.: :....::.:. . :::::.: . :: ..: .:: :..:::.: NP_001 AAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILP 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE4 GVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKR :.:::.:.:: ::: :: :::.::. ::. :: :: ::. . .:. :.::: .:::. NP_001 GLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKK 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE4 EEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVM ::: .::.: :. .::::....:.. .: .:.: : ::.. .:::. ::::.::::.:.: NP_001 EEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAM 290 300 310 320 330 340 360 370 380 390 400 410 pF1KE4 DLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQD .. :::..:..:.:::.::.:::.. .: .. :::. .: ::::::: :: .: : NP_001 GVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLD 350 360 370 380 390 400 420 430 440 450 460 470 pF1KE4 QSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMT . ::: :::.:::::..::.:.::::.:::::.:::::::... .::::.:::::..: NP_001 LQTVRTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKIT 410 420 430 440 450 460 480 490 500 510 520 530 pF1KE4 AELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE--SRKGKQTRQQQEHQK- .:. : .: .::: . . .......:::::.::::.:..::: : ..:. .:. : .: NP_001 GEVQPFIPNIIYGITALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPEVEKA 470 480 490 500 510 520 540 550 pF1KE4 -YMVPLQASAQEKNGL .::: NP_001 SQRIPLQPHGPGLGSS 530 540 >>NP_001171662 (OMIM: 607581) solute carrier family 22 m (451 aa) initn: 1575 init1: 1513 opt: 1592 Z-score: 1767.3 bits: 336.5 E(85289): 1.1e-91 Smith-Waterman score: 1592; 52.4% identity (81.5% similar) in 443 aa overlap (103-541:2-442) 80 90 100 110 120 130 pF1KE4 GQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRA ::: :::.: ::: ..:::::::::. NP_001 MEPCLDGWVY-NST-KDSIVTEWDLVCNSNK 10 20 140 150 160 170 180 190 pF1KE4 LRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFR :...:::..:.:.:.:..:.: :.::.::: .: .:: :.::. :::.:.:::: .:: NP_001 LKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFR 30 40 50 60 70 80 200 210 220 230 240 250 pF1KE4 LLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQL .: :....::.:. . :::::.: . :: ..: .:: :..:::.: :.:::.:.:: ::: NP_001 FLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQL 90 100 110 120 130 140 260 270 280 290 300 310 pF1KE4 LVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRAS :: :::.::. ::. :: :: ::. . .:. :.::: .:::.::: .::.: :. . NP_001 TVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLN 150 160 170 180 190 200 320 330 340 350 360 370 pF1KE4 LQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQV ::::....:.. .: .:.: : ::.. .:::. ::::.::::.:.: .. :::..:..:. NP_001 LQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQI 210 220 230 240 250 260 380 390 400 410 420 430 pF1KE4 IFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKG :::.::.:::.. .: .. :::. .: ::::::: :: .: : . ::: :::.::: NP_001 IFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLDLQTVRTVLAVFGKG 270 280 290 300 310 320 440 450 460 470 480 490 pF1KE4 CLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGA ::..::.:.::::.:::::.:::::::... .::::.:::::..:.:. : .: .::: NP_001 CLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGI 330 340 350 360 370 380 500 510 520 530 540 pF1KE4 VPVAASAVTVLLPETLGQPLPDTVQDLE--SRKGKQTRQQQEHQK--YMVPLQASAQEKN . . .......:::::.::::.:..::: : ..:. .:. : .: .::: NP_001 TALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPEVEKASQRIPLQPHGPGLG 390 400 410 420 430 440 550 pF1KE4 GL NP_001 SS 450 >>NP_060954 (OMIM: 607097) solute carrier family 22 memb (550 aa) initn: 1383 init1: 675 opt: 1490 Z-score: 1653.2 bits: 315.7 E(85289): 2.4e-85 Smith-Waterman score: 1490; 42.6% identity (74.4% similar) in 542 aa overlap (1-532:1-541) 10 20 30 40 50 pF1KE4 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRP-------PA :::. ::.:.:::: :: .:: .:: :.. :. :.::.:::: :.: . NP_060 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE4 DANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGA-TEPCTDGWIYD ..:.. .. : . .: . :..: :: .::: : :.: .. . : ::::.:::.:: NP_060 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE4 NSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQT :.: ::::..:::::: ..:. :.::..: :.:.:....: :. :.::. .: :: NP_060 RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE4 AVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSL ::.:: . :::.: :::..:.......::: :. .:: ::: :: . :..: ..: NP_060 AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE4 GQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVA :: :.:.:.:. :: ::: .:.::::. . ::.. ::::: .:. : .:. :..:: NP_060 GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE4 RINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA ::::..: . .:..::: .:...:.. .: :...:. :.:: . .. :. .. NP_060 RINGHKE-AKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLIS 310 320 330 340 350 360 370 380 390 400 410 pF1KE4 YYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLN :::::.:::..: .:.:.:..:::::. .. . :... :::: : .. .::. :: : NP_060 YYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILAN 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE4 GVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVS ..::: . .:. .:::::::.. :..:. .: .::.:: .:.:. :. :..:.:.... NP_060 MLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMG 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE4 PLVSMTAELYPSMPLFIYGAVPVAASAVTVL-LPETLGQPLPDTVQDLESRKGKQTR-QQ ::. :. . : .: ..::.. .:.: :... :::: : :::::.:::::.:. .. .. NP_060 PLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNR 480 490 500 510 520 530 540 550 pF1KE4 QEHQKYMVPLQASAQEKNGL :: NP_060 QEAVTVESTSL 540 550 >>NP_653186 (OMIM: 220150,607096) solute carrier family (553 aa) initn: 1645 init1: 1395 opt: 1476 Z-score: 1637.7 bits: 312.8 E(85289): 1.8e-84 Smith-Waterman score: 1621; 46.3% identity (75.5% similar) in 538 aa overlap (1-526:1-537) 10 20 30 40 50 pF1KE4 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPP------AD :::..::. :::.:::: .:. ... .. . ... :.::.::.:.:.: : :. NP_653 MAFSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQ 10 20 30 40 50 60 60 70 80 90 100 pF1KE4 AN----LSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGA-TEPCTDGW :. :: .. : . .: . .:..: :: .::: : :.: .. . : ::::.::: NP_653 ASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGW 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE4 IYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNY .:: : : ::::..:.:::. .::. .:::.:..:.:.:: . : .::.::: :: .: NP_653 VYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE4 LQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYV :: :: :: ::::: ::.:: ::.: ..:.::. .: :: .:: ..: : :: . NP_653 LQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE4 YSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQ .:.:. : :.:::.: : :::.::.::: :.:::.. ::::: ..:::: :. : NP_653 FSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELW 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE4 RVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSML-WFA ::: :::: :. ::: .....::.::. :: ::: : :: . :.: : ::: NP_653 RVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLR-FRTCISTLCWFA 310 320 330 340 350 350 360 370 380 390 400 pF1KE4 TSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGIC .:...::..:::..: .:.:.:...:.::.:::. ..:... :::::. :.:::::.: NP_653 FGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLC 360 370 380 390 400 410 410 420 430 440 450 460 pF1KE4 ILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVG :: : ..:.... .:..::::: : ..:.:.:: .:..::.::..:.:..:.:. :: : NP_653 ILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGG 420 430 440 450 460 470 470 480 490 500 510 520 pF1KE4 SIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRKGKQTR .:..::: . . : .::..::.::: .. ...::::: . :::::.::.... :. NP_653 AILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQNQAVKKAT 480 490 500 510 520 530 530 540 550 pF1KE4 QQQEHQKYMVPLQASAQEKNGL NP_653 HGTLGNSVLKSTQF 540 550 550 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 23:59:07 2016 done: Sun Nov 6 23:59:09 2016 Total Scan time: 9.740 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]