FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE4539, 622 aa 1>>>pF1KE4539 622 - 622 aa - 622 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2106+/-0.000777; mu= 15.3462+/- 0.047 mean_var=89.3846+/-17.923, 0's: 0 Z-trim(110.5): 12 B-trim: 0 in 0/51 Lambda= 0.135657 statistics sampled from 11660 (11668) to 11660 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.358), width: 16 Scan time: 3.430 The best scores are: opt bits E(32554) CCDS45370.1 MSLN gene_id:10232|Hs108|chr16 ( 622) 4145 821.3 0 CCDS32356.1 MSLN gene_id:10232|Hs108|chr16 ( 630) 4119 816.2 0 >>CCDS45370.1 MSLN gene_id:10232|Hs108|chr16 (622 aa) initn: 4145 init1: 4145 opt: 4145 Z-score: 4383.7 bits: 821.3 E(32554): 0 Smith-Waterman score: 4145; 99.8% identity (99.8% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KE4 MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 ACPSGKKAPEIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE4 PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQVATLIDRFVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQVATLIDRFVK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE4 GRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQLDVLYPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQLDVLYPKA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE4 RLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVLPLTVAEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVLPLTVAEVQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE4 KLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLSMQEALSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLSMQEALSGT 550 560 570 580 590 600 610 620 pF1KE4 PCLLGPGPVLTVLALLLASTLA :::::::::::::::::::::: CCDS45 PCLLGPGPVLTVLALLLASTLA 610 620 >>CCDS32356.1 MSLN gene_id:10232|Hs108|chr16 (630 aa) initn: 2757 init1: 2757 opt: 4119 Z-score: 4356.2 bits: 816.2 E(32554): 0 Smith-Waterman score: 4119; 98.6% identity (98.6% similar) in 630 aa overlap (1-622:1-630) 10 20 30 40 50 60 pF1KE4 MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 ACPSGKKAPEIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 ACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELY 310 320 330 340 350 360 370 380 390 400 410 pF1KE4 PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQ--------VA :::::::::::::::::::::::::::::::::::::::::::::::::: :: CCDS32 PQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQAPRRPLPQVA 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE4 TLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQ 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE4 LDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE4 PLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 PLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLS 550 560 570 580 590 600 600 610 620 pF1KE4 MQEALSGTPCLLGPGPVLTVLALLLASTLA :::::::::::::::::::::::::::::: CCDS32 MQEALSGTPCLLGPGPVLTVLALLLASTLA 610 620 630 622 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 17:38:41 2016 done: Mon Nov 7 17:38:41 2016 Total Scan time: 3.430 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]