FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE4564, 702 aa 1>>>pF1KE4564 702 - 702 aa - 702 aa Library: /omim/omim.rfq.tfa 61127809 residues in 85815 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3772+/-0.000525; mu= 4.0403+/- 0.033 mean_var=251.6431+/-53.988, 0's: 0 Z-trim(112.8): 330 B-trim: 1035 in 2/58 Lambda= 0.080850 statistics sampled from 21525 (21999) to 21525 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.584), E-opt: 0.2 (0.256), width: 16 Scan time: 10.950 The best scores are: opt bits E(85815) NP_001278413 (OMIM: 114890) carcinoembryonic antig ( 702) 4700 563.1 1.4e-159 NP_004354 (OMIM: 114890) carcinoembryonic antigen- ( 702) 4700 563.1 1.4e-159 NP_001295327 (OMIM: 114890) carcinoembryonic antig ( 701) 4683 561.1 5.3e-159 XP_016881634 (OMIM: 114890) PREDICTED: carcinoembr ( 701) 4683 561.1 5.3e-159 XP_005258470 (OMIM: 114890) PREDICTED: carcinoembr ( 524) 3367 407.4 7.1e-113 XP_011524624 (OMIM: 114890) PREDICTED: carcinoembr ( 524) 2801 341.4 5.3e-93 XP_016881635 (OMIM: 114890) PREDICTED: carcinoembr ( 617) 2638 322.5 3.1e-87 NP_001703 (OMIM: 109770) carcinoembryonic antigen- ( 526) 2047 253.5 1.6e-66 NP_001020083 (OMIM: 109770) carcinoembryonic antig ( 464) 2041 252.7 2.4e-66 NP_001192273 (OMIM: 109770) carcinoembryonic antig ( 468) 2041 252.7 2.4e-66 NP_002474 (OMIM: 163980) carcinoembryonic antigen- ( 344) 1834 228.4 3.6e-59 XP_011525292 (OMIM: 163980) PREDICTED: carcinoembr ( 324) 1828 227.7 5.6e-59 XP_011525508 (OMIM: 109770) PREDICTED: carcinoembr ( 351) 1809 225.5 2.7e-58 NP_001171745 (OMIM: 109770) carcinoembryonic antig ( 368) 1803 224.8 4.6e-58 NP_001171742 (OMIM: 109770) carcinoembryonic antig ( 430) 1803 224.9 5.1e-58 NP_001171744 (OMIM: 109770) carcinoembryonic antig ( 461) 1803 224.9 5.4e-58 XP_016881683 (OMIM: 615747) PREDICTED: carcinoembr ( 368) 1620 203.5 1.2e-51 XP_011524642 (OMIM: 615747) PREDICTED: carcinoembr ( 415) 1620 203.5 1.3e-51 XP_016881685 (OMIM: 615747) PREDICTED: carcinoembr ( 331) 1615 202.9 1.7e-51 XP_016881684 (OMIM: 615747) PREDICTED: carcinoembr ( 349) 1612 202.5 2.3e-51 NP_001807 (OMIM: 615747) carcinoembryonic antigen- ( 349) 1612 202.5 2.3e-51 XP_011524643 (OMIM: 615747) PREDICTED: carcinoembr ( 255) 1202 154.6 4.5e-37 XP_016881687 (OMIM: 615747) PREDICTED: carcinoembr ( 255) 1202 154.6 4.5e-37 XP_011524644 (OMIM: 615747) PREDICTED: carcinoembr ( 255) 1202 154.6 4.5e-37 NP_001288637 (OMIM: 176398) pregnancy-specific bet ( 333) 1192 153.5 1.2e-36 XP_005259132 (OMIM: 176398) PREDICTED: pregnancy-s ( 402) 1192 153.6 1.4e-36 XP_011525428 (OMIM: 176392) PREDICTED: pregnancy-s ( 357) 1176 151.7 4.7e-36 NP_002776 (OMIM: 176401) pregnancy-specific beta-1 ( 335) 1170 151.0 7.3e-36 XP_016882494 (OMIM: 176398) PREDICTED: pregnancy-s ( 402) 1155 149.3 2.8e-35 XP_016882491 (OMIM: 176393) PREDICTED: pregnancy-s ( 333) 1144 147.9 5.9e-35 XP_016882488 (OMIM: 176393) PREDICTED: pregnancy-s ( 349) 1089 141.5 5.2e-33 XP_016881686 (OMIM: 615747) PREDICTED: carcinoembr ( 295) 943 124.4 6.2e-28 XP_011525429 (OMIM: 176392) PREDICTED: pregnancy-s ( 272) 858 114.5 5.7e-25 NP_001264092 (OMIM: 609142) carcinoembryonic antig ( 212) 813 109.1 1.8e-23 NP_001806 (OMIM: 609142) carcinoembryonic antigen- ( 252) 813 109.2 2.1e-23 NP_001284702 (OMIM: 176390) pregnancy-specific bet ( 428) 785 106.2 2.8e-22 NP_066296 (OMIM: 176392) pregnancy-specific beta-1 ( 428) 784 106.0 3.1e-22 NP_001171755 (OMIM: 176390) pregnancy-specific bet ( 417) 778 105.3 4.9e-22 NP_008836 (OMIM: 176390) pregnancy-specific beta-1 ( 426) 777 105.2 5.4e-22 NP_001171754 (OMIM: 176390) pregnancy-specific bet ( 419) 775 105.0 6.3e-22 NP_001303268 (OMIM: 176393) pregnancy-specific bet ( 297) 771 104.4 6.9e-22 NP_002774 (OMIM: 176396) putative pregnancy-specif ( 419) 773 104.8 7.4e-22 NP_001193579 (OMIM: 176396) putative pregnancy-spe ( 297) 766 103.8 1e-21 XP_016882486 (OMIM: 176393) PREDICTED: pregnancy-s ( 426) 768 104.2 1.1e-21 XP_016882484 (OMIM: 176393) PREDICTED: pregnancy-s ( 442) 768 104.2 1.1e-21 NP_001123640 (OMIM: 176397) pregnancy-specific bet ( 297) 764 103.5 1.2e-21 NP_002771 (OMIM: 176393) pregnancy-specific beta-1 ( 419) 766 103.9 1.3e-21 XP_016882485 (OMIM: 176393) PREDICTED: pregnancy-s ( 435) 766 104.0 1.3e-21 XP_011525289 (OMIM: 176397) PREDICTED: pregnancy-s ( 306) 761 103.2 1.6e-21 NP_874366 (OMIM: 176397) pregnancy-specific beta-1 ( 426) 762 103.5 1.8e-21 >>NP_001278413 (OMIM: 114890) carcinoembryonic antigen-r (702 aa) initn: 4700 init1: 4700 opt: 4700 Z-score: 2986.3 bits: 563.1 E(85815): 1.4e-159 Smith-Waterman score: 4700; 99.9% identity (100.0% similar) in 702 aa overlap (1-702:1-702) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP :::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::: NP_001 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE4 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE4 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE4 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE4 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE4 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL 610 620 630 640 650 660 670 680 690 700 pF1KE4 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI :::::::::::::::::::::::::::::::::::::::::: NP_001 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 670 680 690 700 >>NP_004354 (OMIM: 114890) carcinoembryonic antigen-rela (702 aa) initn: 4700 init1: 4700 opt: 4700 Z-score: 2986.3 bits: 563.1 E(85815): 1.4e-159 Smith-Waterman score: 4700; 99.9% identity (100.0% similar) in 702 aa overlap (1-702:1-702) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP :::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::: NP_004 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE4 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE4 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE4 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE4 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE4 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL 610 620 630 640 650 660 670 680 690 700 pF1KE4 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI :::::::::::::::::::::::::::::::::::::::::: NP_004 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 670 680 690 700 >>NP_001295327 (OMIM: 114890) carcinoembryonic antigen-r (701 aa) initn: 2547 init1: 2547 opt: 4683 Z-score: 2975.6 bits: 561.1 E(85815): 5.3e-159 Smith-Waterman score: 4683; 99.7% identity (99.9% similar) in 702 aa overlap (1-702:1-701) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP :::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::: NP_001 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_001 AHNSDTGLNRTTVTTITVY-EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN 310 320 330 340 350 370 380 390 400 410 420 pF1KE4 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KE4 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE4 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE4 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KE4 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL 600 610 620 630 640 650 670 680 690 700 pF1KE4 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI :::::::::::::::::::::::::::::::::::::::::: NP_001 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 660 670 680 690 700 >>XP_016881634 (OMIM: 114890) PREDICTED: carcinoembryoni (701 aa) initn: 2547 init1: 2547 opt: 4683 Z-score: 2975.6 bits: 561.1 E(85815): 5.3e-159 Smith-Waterman score: 4683; 99.7% identity (99.9% similar) in 702 aa overlap (1-702:1-701) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP :::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::: XP_016 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 AHNSDTGLNRTTVTTITVY-EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN 310 320 330 340 350 370 380 390 400 410 420 pF1KE4 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KE4 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE4 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE4 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP 540 550 560 570 580 590 610 620 630 640 650 660 pF1KE4 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL 600 610 620 630 640 650 670 680 690 700 pF1KE4 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI :::::::::::::::::::::::::::::::::::::::::: XP_016 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 660 670 680 690 700 >>XP_005258470 (OMIM: 114890) PREDICTED: carcinoembryoni (524 aa) initn: 3354 init1: 3354 opt: 3367 Z-score: 2147.5 bits: 407.4 E(85815): 7.1e-113 Smith-Waterman score: 3367; 97.8% identity (99.2% similar) in 510 aa overlap (1-510:1-510) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP :::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::: XP_005 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE4 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE4 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE4 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE4 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS :::::::::::::::::: .:..:.. . XP_005 NSASGHSRTTVKTITVSASGTSPGLSAGATVGIMIGVLVGVALI 490 500 510 520 >>XP_011524624 (OMIM: 114890) PREDICTED: carcinoembryoni (524 aa) initn: 2788 init1: 2788 opt: 2801 Z-score: 1790.7 bits: 341.4 E(85815): 5.3e-93 Smith-Waterman score: 3134; 74.5% identity (74.6% similar) in 702 aa overlap (1-702:1-524) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP :::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: XP_011 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPD-- 190 200 210 220 230 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ XP_011 ------------------------------------------------------------ 310 320 330 340 350 360 pF1KE4 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN XP_011 ------------------------------------------------------------ 370 380 390 400 410 420 pF1KE4 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI :::: XP_011 --------------------------------------------------------DPTI 240 430 440 450 460 470 480 pF1KE4 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN 250 260 270 280 290 300 490 500 510 520 530 540 pF1KE4 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS 310 320 330 340 350 360 550 560 570 580 590 600 pF1KE4 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP 370 380 390 400 410 420 610 620 630 640 650 660 pF1KE4 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL 430 440 450 460 470 480 670 680 690 700 pF1KE4 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI :::::::::::::::::::::::::::::::::::::::::: XP_011 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 490 500 510 520 >>XP_016881635 (OMIM: 114890) PREDICTED: carcinoembryoni (617 aa) initn: 2559 init1: 2559 opt: 2638 Z-score: 1687.1 bits: 322.5 E(85815): 3.1e-87 Smith-Waterman score: 3944; 87.6% identity (87.9% similar) in 702 aa overlap (1-702:1-617) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP :::::::::::::::::::::::::::::.:::::::::::::::::::::::: XP_016 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVL------ 190 200 210 220 230 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ XP_016 ------------------------------------------------------------ 310 320 330 340 350 360 pF1KE4 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN .:::::::::::::::::::::::::::::::::::::::: XP_016 -------------------SEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN 240 250 260 270 370 380 390 400 410 420 pF1KE4 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI 280 290 300 310 320 330 430 440 450 460 470 480 pF1KE4 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN 340 350 360 370 380 390 490 500 510 520 530 540 pF1KE4 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS 400 410 420 430 440 450 550 560 570 580 590 600 pF1KE4 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP 460 470 480 490 500 510 610 620 630 640 650 660 pF1KE4 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL 520 530 540 550 560 570 670 680 690 700 pF1KE4 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI :::::::::::::::::::::::::::::::::::::::::: XP_016 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 580 590 600 610 >>NP_001703 (OMIM: 109770) carcinoembryonic antigen-rela (526 aa) initn: 2363 init1: 1806 opt: 2047 Z-score: 1315.4 bits: 253.5 E(85815): 1.6e-66 Smith-Waterman score: 2047; 62.8% identity (79.3% similar) in 511 aa overlap (5-510:5-512) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ ::: :: .::: :::::::::::::::::.:: :: ::::::::::::::::::: NP_001 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY .::::::::::::::::::.::.::::::::::: :::: :::::::::::. ::::::: NP_001 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV ::.:::::::::::::::.:::::::::::::::.::::::::::::::::::.:::::. NP_001 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP ::::::::::::::::::::::..:::::.. :.:: :::::: ::: : ::: ::::.: NP_001 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ :::: .: :: : ::.:::.:::::::::::..::::::::::::::::::::::::::. NP_001 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 250 260 270 280 290 300 310 320 330 340 350 pF1KE4 AHNSDTGLNRTTVTTITVYAEPP---KPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW :.:: :: ::::: :: : : :: : ..... . :.:.: ::: . . . :. NP_001 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE4 VNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYG--P .::::: : :..::. : ::.. : :.:.: : : . : .: ..:::..::: :. : NP_001 FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE4 DDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLY .. .::. :. ... .: : .: :. . ... ... . :. NP_001 QENGLSPGAI---AGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHT 430 440 450 460 470 480 490 500 510 520 530 pF1KE4 TCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWW ..:. . ...: .:.. :. : :.. : NP_001 QDHSNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKKQ 480 490 500 510 520 540 550 560 570 580 590 pF1KE4 VNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDT >>NP_001020083 (OMIM: 109770) carcinoembryonic antigen-r (464 aa) initn: 2363 init1: 1806 opt: 2041 Z-score: 1312.3 bits: 252.7 E(85815): 2.4e-66 Smith-Waterman score: 2041; 72.8% identity (85.6% similar) in 423 aa overlap (5-422:5-427) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ ::: :: .::: :::::::::::::::::.:: :: ::::::::::::::::::: NP_001 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY .::::::::::::::::::.::.::::::::::: :::: :::::::::::. ::::::: NP_001 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV ::.:::::::::::::::.:::::::::::::::.::::::::::::::::::.:::::. NP_001 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP ::::::::::::::::::::::..:::::.. :.:: :::::: ::: : ::: ::::.: NP_001 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ :::: .: :: : ::.:::.:::::::::::..::::::::::::::::::::::::::. NP_001 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 250 260 270 280 290 300 310 320 330 340 350 pF1KE4 AHNSDTGLNRTTVTTITVYAEPP---KPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW :.:: :: ::::: :: : : :: : ..... . :.:.: ::: . . . :. NP_001 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE4 VNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYG--P .::::: : :..::. : ::.. : :.:.: : : . : .: ..:::..::: :. : NP_001 FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE4 DDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLY .. .:: NP_001 QENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGSSGPLQ 430 440 450 460 >>NP_001192273 (OMIM: 109770) carcinoembryonic antigen-r (468 aa) initn: 2363 init1: 1806 opt: 2041 Z-score: 1312.2 bits: 252.7 E(85815): 2.4e-66 Smith-Waterman score: 2041; 72.8% identity (85.6% similar) in 423 aa overlap (5-422:5-427) 10 20 30 40 50 60 pF1KE4 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ ::: :: .::: :::::::::::::::::.:: :: ::::::::::::::::::: NP_001 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE4 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY .::::::::::::::::::.::.::::::::::: :::: :::::::::::. ::::::: NP_001 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE4 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV ::.:::::::::::::::.:::::::::::::::.::::::::::::::::::.:::::. NP_001 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE4 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDSASYKCETQNPVSARRSDSVILNVLYGPDAP ::::::::::::::::::::::..:::::.. :.:: :::::: ::: : ::: ::::.: NP_001 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE4 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ :::: .: :: : ::.:::.:::::::::::..::::::::::::::::::::::::::. NP_001 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 250 260 270 280 290 300 310 320 330 340 350 pF1KE4 AHNSDTGLNRTTVTTITVYAEPP---KPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW :.:: :: ::::: :: : : :: : ..... . :.:.: ::: . . . :. NP_001 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE4 VNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYG--P .::::: : :..::. : ::.. : :.:.: : : . : .: ..:::..::: :. : NP_001 FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE4 DDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLY .. .:: NP_001 QENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRTTPMTHLTR 430 440 450 460 702 residues in 1 query sequences 61127809 residues in 85815 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Jan 12 11:35:57 2017 done: Thu Jan 12 11:35:59 2017 Total Scan time: 10.950 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]