FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE5152, 87 aa 1>>>pF1KE5152 87 - 87 aa - 87 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.4329+/-0.000244; mu= 13.3978+/- 0.015 mean_var=53.5114+/-10.686, 0's: 0 Z-trim(122.0): 35 B-trim: 1069 in 1/56 Lambda= 0.175328 statistics sampled from 39387 (39422) to 39387 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.829), E-opt: 0.2 (0.462), width: 16 Scan time: 3.860 The best scores are: opt bits E(85289) NP_005962 (OMIM: 604996) FXYD domain-containing io ( 87) 608 160.2 3.8e-40 XP_016882367 (OMIM: 604996) PREDICTED: FXYD domain ( 87) 608 160.2 3.8e-40 XP_016882366 (OMIM: 604996) PREDICTED: FXYD domain ( 87) 608 160.2 3.8e-40 NP_001129483 (OMIM: 604996) FXYD domain-containing ( 87) 608 160.2 3.8e-40 NP_001129479 (OMIM: 604996) FXYD domain-containing ( 144) 608 160.4 5.6e-40 NP_001129480 (OMIM: 604996) FXYD domain-containing ( 96) 412 110.7 3.4e-25 NP_001129484 (OMIM: 604996) FXYD domain-containing ( 113) 412 110.7 3.9e-25 NP_068710 (OMIM: 604996) FXYD domain-containing io ( 113) 412 110.7 3.9e-25 XP_005259053 (OMIM: 604996) PREDICTED: FXYD domain ( 113) 412 110.7 3.9e-25 XP_011525334 (OMIM: 604996) PREDICTED: FXYD domain ( 170) 412 110.9 5.3e-25 NP_775183 (OMIM: 616926) FXYD domain-containing io ( 89) 302 82.8 7.7e-17 NP_001171892 (OMIM: 616926) FXYD domain-containing ( 89) 302 82.8 7.7e-17 NP_001129481 (OMIM: 604996) FXYD domain-containing ( 61) 211 59.7 4.9e-10 NP_001129482 (OMIM: 604996) FXYD domain-containing ( 61) 211 59.7 4.9e-10 NP_001265647 (OMIM: 602359) phospholemman precurso ( 92) 211 59.8 6.7e-10 XP_016882363 (OMIM: 602359) PREDICTED: phospholemm ( 92) 211 59.8 6.7e-10 NP_001265646 (OMIM: 602359) phospholemman precurso ( 92) 211 59.8 6.7e-10 NP_005022 (OMIM: 602359) phospholemman precursor [ ( 92) 211 59.8 6.7e-10 NP_068702 (OMIM: 602359) phospholemman precursor [ ( 92) 211 59.8 6.7e-10 XP_016882364 (OMIM: 602359) PREDICTED: phospholemm ( 110) 211 59.9 7.7e-10 XP_016882365 (OMIM: 602359) PREDICTED: phospholemm ( 110) 211 59.9 7.7e-10 NP_001158304 (OMIM: 606683) FXYD domain-containing ( 95) 193 55.3 1.6e-08 NP_001158308 (OMIM: 606683) FXYD domain-containing ( 95) 193 55.3 1.6e-08 NP_001158303 (OMIM: 606683) FXYD domain-containing ( 95) 193 55.3 1.6e-08 NP_001158309 (OMIM: 606683) FXYD domain-containing ( 95) 193 55.3 1.6e-08 NP_071286 (OMIM: 606683) FXYD domain-containing io ( 95) 193 55.3 1.6e-08 NP_071289 (OMIM: 606684) FXYD domain-containing io ( 80) 135 40.6 0.00037 NP_067614 (OMIM: 154020,601814) sodium/potassium-t ( 64) 132 39.7 0.00052 NP_001671 (OMIM: 154020,601814) sodium/potassium-t ( 66) 129 39.0 0.00091 NP_001307842 (OMIM: 606669) FXYD domain-containing ( 147) 125 38.2 0.0034 NP_054883 (OMIM: 606669) FXYD domain-containing io ( 178) 125 38.3 0.0039 NP_659003 (OMIM: 606669) FXYD domain-containing io ( 178) 125 38.3 0.0039 NP_001158077 (OMIM: 606669) FXYD domain-containing ( 178) 125 38.3 0.0039 >>NP_005962 (OMIM: 604996) FXYD domain-containing ion tr (87 aa) initn: 608 init1: 608 opt: 608 Z-score: 841.8 bits: 160.2 E(85289): 3.8e-40 Smith-Waterman score: 608; 100.0% identity (100.0% similar) in 87 aa overlap (1-87:1-87) 10 20 30 40 50 60 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK 10 20 30 40 50 60 70 80 pF1KE5 CKCKFGQKSGHHPGETPPLITPGSAQS ::::::::::::::::::::::::::: NP_005 CKCKFGQKSGHHPGETPPLITPGSAQS 70 80 >>XP_016882367 (OMIM: 604996) PREDICTED: FXYD domain-con (87 aa) initn: 608 init1: 608 opt: 608 Z-score: 841.8 bits: 160.2 E(85289): 3.8e-40 Smith-Waterman score: 608; 100.0% identity (100.0% similar) in 87 aa overlap (1-87:1-87) 10 20 30 40 50 60 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK 10 20 30 40 50 60 70 80 pF1KE5 CKCKFGQKSGHHPGETPPLITPGSAQS ::::::::::::::::::::::::::: XP_016 CKCKFGQKSGHHPGETPPLITPGSAQS 70 80 >>XP_016882366 (OMIM: 604996) PREDICTED: FXYD domain-con (87 aa) initn: 608 init1: 608 opt: 608 Z-score: 841.8 bits: 160.2 E(85289): 3.8e-40 Smith-Waterman score: 608; 100.0% identity (100.0% similar) in 87 aa overlap (1-87:1-87) 10 20 30 40 50 60 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK 10 20 30 40 50 60 70 80 pF1KE5 CKCKFGQKSGHHPGETPPLITPGSAQS ::::::::::::::::::::::::::: XP_016 CKCKFGQKSGHHPGETPPLITPGSAQS 70 80 >>NP_001129483 (OMIM: 604996) FXYD domain-containing ion (87 aa) initn: 608 init1: 608 opt: 608 Z-score: 841.8 bits: 160.2 E(85289): 3.8e-40 Smith-Waterman score: 608; 100.0% identity (100.0% similar) in 87 aa overlap (1-87:1-87) 10 20 30 40 50 60 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK 10 20 30 40 50 60 70 80 pF1KE5 CKCKFGQKSGHHPGETPPLITPGSAQS ::::::::::::::::::::::::::: NP_001 CKCKFGQKSGHHPGETPPLITPGSAQS 70 80 >>NP_001129479 (OMIM: 604996) FXYD domain-containing ion (144 aa) initn: 608 init1: 608 opt: 608 Z-score: 838.7 bits: 160.4 E(85289): 5.6e-40 Smith-Waterman score: 608; 100.0% identity (100.0% similar) in 87 aa overlap (1-87:58-144) 10 20 30 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPF :::::::::::::::::::::::::::::: NP_001 FTQSPLHGAAAAYLSAQRDASLPVPGQRSDMQKVTLGLLVFLAGFPVLDANDLEDKNSPF 30 40 50 60 70 80 40 50 60 70 80 pF1KE5 YYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS 90 100 110 120 130 140 >>NP_001129480 (OMIM: 604996) FXYD domain-containing ion (96 aa) initn: 470 init1: 393 opt: 412 Z-score: 573.3 bits: 110.7 E(85289): 3.4e-25 Smith-Waterman score: 422; 72.9% identity (72.9% similar) in 96 aa overlap (1-70:1-96) 10 20 30 40 50 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMS-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEW 10 20 30 40 50 60 60 70 80 pF1KE5 ------------------------AKCKCKFGQKSGHHPGETPPLITPGSAQS :::::::::::: NP_001 RSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSG 70 80 90 >>NP_001129484 (OMIM: 604996) FXYD domain-containing ion (113 aa) initn: 594 init1: 393 opt: 412 Z-score: 572.3 bits: 110.7 E(85289): 3.9e-25 Smith-Waterman score: 546; 77.0% identity (77.0% similar) in 113 aa overlap (1-87:1-113) 10 20 30 40 50 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMS-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEW 10 20 30 40 50 60 60 70 80 pF1KE5 ------------------------AKCKCKFGQKSGHHPGETPPLITPGSAQS ::::::::::::::::::::::::::::: NP_001 RSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS 70 80 90 100 110 >>NP_068710 (OMIM: 604996) FXYD domain-containing ion tr (113 aa) initn: 594 init1: 393 opt: 412 Z-score: 572.3 bits: 110.7 E(85289): 3.9e-25 Smith-Waterman score: 546; 77.0% identity (77.0% similar) in 113 aa overlap (1-87:1-113) 10 20 30 40 50 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMS-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEW 10 20 30 40 50 60 60 70 80 pF1KE5 ------------------------AKCKCKFGQKSGHHPGETPPLITPGSAQS ::::::::::::::::::::::::::::: NP_068 RSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS 70 80 90 100 110 >>XP_005259053 (OMIM: 604996) PREDICTED: FXYD domain-con (113 aa) initn: 594 init1: 393 opt: 412 Z-score: 572.3 bits: 110.7 E(85289): 3.9e-25 Smith-Waterman score: 546; 77.0% identity (77.0% similar) in 113 aa overlap (1-87:1-113) 10 20 30 40 50 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMS-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEW 10 20 30 40 50 60 60 70 80 pF1KE5 ------------------------AKCKCKFGQKSGHHPGETPPLITPGSAQS ::::::::::::::::::::::::::::: XP_005 RSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS 70 80 90 100 110 >>XP_011525334 (OMIM: 604996) PREDICTED: FXYD domain-con (170 aa) initn: 594 init1: 393 opt: 412 Z-score: 569.8 bits: 110.9 E(85289): 5.3e-25 Smith-Waterman score: 546; 77.0% identity (77.0% similar) in 113 aa overlap (1-87:58-170) 10 20 30 pF1KE5 MQKVTLGLLVFLAGFPVLDANDLEDKNSPF :::::::::::::::::::::::::::::: XP_011 FTQSPLHGAAAAYLSAQRDASLPVPGQRSDMQKVTLGLLVFLAGFPVLDANDLEDKNSPF 30 40 50 60 70 80 40 50 60 pF1KE5 YYDWHSLQVGGLICAGVLCAMGIIIVMS--------------------------AKCKCK :::::::::::::::::::::::::::: :::::: XP_011 YYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCK 90 100 110 120 130 140 70 80 pF1KE5 FGQKSGHHPGETPPLITPGSAQS ::::::::::::::::::::::: XP_011 FGQKSGHHPGETPPLITPGSAQS 150 160 170 87 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 22:00:57 2016 done: Mon Nov 7 22:00:58 2016 Total Scan time: 3.860 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]