Result of FASTA (ccds) for
pF1KE5553
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5553, 426 aa
1>>>pF1KE5553 426 - 426 aa - 426 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4308+/-0.00105; mu= 16.4286+/- 0.063
mean_var=59.7908+/-12.309, 0's: 0 Z-trim(102.6): 23 B-trim: 0 in 0/49
Lambda= 0.165866
statistics sampled from 7032 (7042) to 7032 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.216), width: 16
Scan time: 2.200
The best scores are: opt bits E(32554)
CCDS8296.1 PANX1 gene_id:24145|Hs108|chr11 ( 426) 2775 672.8 1.8e-193
CCDS8447.1 PANX3 gene_id:116337|Hs108|chr11 ( 392) 929 231.0 1.6e-60
CCDS54544.1 PANX2 gene_id:56666|Hs108|chr22 ( 643) 456 117.9 2.9e-26
CCDS14085.2 PANX2 gene_id:56666|Hs108|chr22 ( 677) 456 117.9 3e-26
>>CCDS8296.1 PANX1 gene_id:24145|Hs108|chr11 (426 aa)
initn: 2775 init1: 2775 opt: 2775 Z-score: 3586.9 bits: 672.8 E(32554): 1.8e-193
Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)
10 20 30 40 50 60
pF1KE5 MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 YLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 YLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 QSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 QSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 QKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNARQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 IDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNARQR
370 380 390 400 410 420
pF1KE5 LLDSSC
::::::
CCDS82 LLDSSC
>>CCDS8447.1 PANX3 gene_id:116337|Hs108|chr11 (392 aa)
initn: 927 init1: 353 opt: 929 Z-score: 1200.2 bits: 231.0 E(32554): 1.6e-60
Smith-Waterman score: 929; 43.3% identity (72.5% similar) in 360 aa overlap (1-357:1-355)
10 20 30 40 50 60
pF1KE5 MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISI
:..:. :.::..:: :: . :..::::::: .:..: .::: ::::.:::::::.:
CCDS84 MSLAHTAAEYMLSDALLPDRRGPRLKGLRLELPLDRIVKFVAVGSPLLLMSLAFAQEFSS
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 GTQISCFSPSSFSWRQAAFVDSYCWAAV-QQKNSLQSESGNLPLWLHKFFPYILLLFAIL
:. :::::::.:: ::::.::: :: .. ..:.. ... :: :: .:: :: .:.:
CCDS84 GSPISCFSPSNFSIRQAAYVDSSCWDSLLHHKQDGPGQDKMKSLWPHKALPYSLLALALL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 LYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENL
.::: :.:..::.: . ::: ::. :::: :::.:. .. : .:. . : : : :
CCDS84 MYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHM--LKIRQKS-SDPYVFWNE
130 140 150 160 170
180 190 200 210 220 230
pF1KE5 GQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSS
.. . : .:..:..:.:: :. :..:. :. : ::. . .:::..
CCDS84 LEKARK--ERYFEFPLLERYLACKQRSHSLVATYLLRNSLLLIFTSATYLYLGHFHLDVF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 LSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPF
...:: ::::.:.: ... ::. . :.: ...:::..:. ....:..:.::..:.:
CCDS84 FQEEFSCSIKTGLLSDETHVPNLITCRLTSLSIFQIVSLSSVAIYTILVPVIIYNLTRLC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 RQKTDVLKVYEILPTFDVLHFKSEG--YNDLSLYNLFLEENISEVKSYKCLKVLENIKSS
: .:.:::.::.::.: : : :::.. :::. ::::. :.. :.:: .:..
CCDS84 RWDKRLLSVYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDT
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 GQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNA
CCDS84 TTQKHNIDTVVDFMTLLAGLEPSKPKHLTNSACDEHP
360 370 380 390
>>CCDS54544.1 PANX2 gene_id:56666|Hs108|chr22 (643 aa)
initn: 314 init1: 206 opt: 456 Z-score: 585.0 bits: 117.9 E(32554): 2.9e-26
Smith-Waterman score: 456; 27.3% identity (63.8% similar) in 337 aa overlap (28-353:44-369)
10 20 30 40 50
pF1KE5 MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQE
:.::: :..:: .: .:.::..:.:...
CCDS54 ALLAGEKLRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTVLVPILLVTLVFTKN
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE5 ISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNL-P-LWLHKFFPYILLL
.. : :..: .:. :: .. .::: .. ...: . ...: : :. :::.:: ::
CCDS54 FA-EEPIYCYTPHNFTRDQALYARGYCW--TELRDALPGVDASLWPSLFEHKFLPYALLA
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE5 FAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAI--KAAKSARDLDMRDGACSVP
:: ..:.: : :.: :. .. :.:.:...:.:. :.:: .: : .... . :
CCDS54 FAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKG-----P
140 150 160 170 180
180 190 200 210 220 230
pF1KE5 GVTENLGQSLWEVSESHFKYP---IVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIY
:.:: . . : .:.. : : . :.::. . :: : :.. ..: :.. . :
CCDS54 GITEREKREIIENAEKE-KSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSAVPISY
190 200 210 220 230 240
240 250 260 270 280
pF1KE5 LGYYFSLSSLSDEFVCSIKSGILRNDSTVPD-QFQCKLIAVGIFQLLSVINLVVYVLLAP
: :.. .. ..::.:.. .. .. : . .::: .: . .... ...:. ..
CCDS54 LCTYYA-TQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAGVDIVLLCVMNL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE5 VVVYTL---FVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYK
... .: :. ::... .. . . ... . :... .: .:: ...:: .
CCDS54 IILVNLIHLFI-FRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLN
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE5 CLKVLENIKSSGQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDS
: . :
CCDS54 RLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEPPV
370 380 390 400 410 420
>>CCDS14085.2 PANX2 gene_id:56666|Hs108|chr22 (677 aa)
initn: 252 init1: 206 opt: 456 Z-score: 584.6 bits: 117.9 E(32554): 3e-26
Smith-Waterman score: 456; 27.3% identity (63.8% similar) in 337 aa overlap (28-353:44-369)
10 20 30 40 50
pF1KE5 MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQE
:.::: :..:: .: .:.::..:.:...
CCDS14 ALLAGEKLRELILPGAQDDKAGALAALLLQLKLELPFDRVVTIGTVLVPILLVTLVFTKN
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE5 ISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNL-P-LWLHKFFPYILLL
.. : :..: .:. :: .. .::: .. ...: . ...: : :. :::.:: ::
CCDS14 FA-EEPIYCYTPHNFTRDQALYARGYCW--TELRDALPGVDASLWPSLFEHKFLPYALLA
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE5 FAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAI--KAAKSARDLDMRDGACSVP
:: ..:.: : :.: :. .. :.:.:...:.:. :.:: .: : .... . :
CCDS14 FAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKG-----P
140 150 160 170 180
180 190 200 210 220 230
pF1KE5 GVTENLGQSLWEVSESHFKYP---IVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIY
:.:: . . : .:.. : : . :.::. . :: : :.. ..: :.. . :
CCDS14 GITEREKREIIENAEKE-KSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSAVPISY
190 200 210 220 230 240
240 250 260 270 280
pF1KE5 LGYYFSLSSLSDEFVCSIKSGILRNDSTVPD-QFQCKLIAVGIFQLLSVINLVVYVLLAP
: :.. .. ..::.:.. .. .. : . .::: .: . .... ...:. ..
CCDS14 LCTYYA-TQKQNEFTCALGASPDGAAGAGPAVRVSCKLPSVQLQRIIAGVDIVLLCVMNL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE5 VVVYTL---FVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYK
... .: :. ::... .. . . ... . :... .: .:: ...:: .
CCDS14 IILVNLIHLFI-FRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLN
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE5 CLKVLENIKSSGQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDS
: . :
CCDS14 RLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEPPV
370 380 390 400 410 420
426 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:45:52 2016 done: Tue Nov 8 01:45:53 2016
Total Scan time: 2.200 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]