FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE6561, 160 aa 1>>>pF1KE6561 160 - 160 aa - 160 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9351+/-0.000875; mu= 14.2271+/- 0.052 mean_var=64.7320+/-13.495, 0's: 0 Z-trim(105.9): 41 B-trim: 65 in 1/50 Lambda= 0.159410 statistics sampled from 8642 (8678) to 8642 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.267), width: 16 Scan time: 1.740 The best scores are: opt bits E(32554) CCDS11168.1 PMP22 gene_id:5376|Hs108|chr17 ( 160) 1052 250.3 3.8e-67 CCDS82078.1 PMP22 gene_id:5376|Hs108|chr17 ( 118) 688 166.5 4.7e-42 CCDS12715.1 EMP3 gene_id:2014|Hs108|chr19 ( 163) 448 111.4 2.5e-25 CCDS10541.1 EMP2 gene_id:2013|Hs108|chr16 ( 167) 432 107.7 3.3e-24 CCDS8660.1 EMP1 gene_id:2012|Hs108|chr12 ( 157) 426 106.3 8.1e-24 >>CCDS11168.1 PMP22 gene_id:5376|Hs108|chr17 (160 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 1319.0 bits: 250.3 E(32554): 3.8e-67 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 160 aa overlap (1-160:1-160) 10 20 30 40 50 60 pF1KE6 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE6 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR 70 80 90 100 110 120 130 140 150 160 pF1KE6 HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE :::::::::::::::::::::::::::::::::::::::: CCDS11 HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 130 140 150 160 >>CCDS82078.1 PMP22 gene_id:5376|Hs108|chr17 (118 aa) initn: 688 init1: 688 opt: 688 Z-score: 868.5 bits: 166.5 E(32554): 4.7e-42 Smith-Waterman score: 688; 100.0% identity (100.0% similar) in 106 aa overlap (1-106:1-106) 10 20 30 40 50 60 pF1KE6 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE6 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR :::::::::::::::::::::::::::::::::::::::::::::: CCDS82 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAESNSSQMCGYRD 70 80 90 100 110 130 140 150 160 pF1KE6 HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE >>CCDS12715.1 EMP3 gene_id:2014|Hs108|chr19 (163 aa) initn: 520 init1: 260 opt: 448 Z-score: 568.2 bits: 111.4 E(32554): 2.5e-25 Smith-Waterman score: 448; 43.3% identity (73.8% similar) in 164 aa overlap (1-160:1-163) 10 20 30 40 50 pF1KE6 MLLLLLSIIVLHVAVLVLLFVSTI-VSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPN : :::: . .::. .:.::::.:. : : . . .. .:: .:. ... .. : . : : CCDS12 MSLLLLVVSALHILILILLFVATLDKSWWTLPGKESLNLWYDCTWNNDTKTWACSNVSEN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE6 EWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTV ::..::. :.::.:. ::..::. ::.:. .:: :: ::. :. ... :...: ::.. CCDS12 GWLKAVQVLMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYAI 70 80 90 100 110 120 120 130 140 150 160 pF1KE6 RHPEWHLNSDY---SYGFAYILAWVAFPLALLSGVIYVILRKRE : : :.. :.:. . ::::::::::.::.::. ::::: CCDS12 -HAEEILEKHPRGGSFGYCFALAWVAFPLALVSGIIYIHLRKRE 130 140 150 160 >>CCDS10541.1 EMP2 gene_id:2013|Hs108|chr16 (167 aa) initn: 454 init1: 211 opt: 432 Z-score: 548.2 bits: 107.7 E(32554): 3.3e-24 Smith-Waterman score: 432; 42.9% identity (74.1% similar) in 170 aa overlap (1-160:1-167) 10 20 30 40 50 60 pF1KE6 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE ::.:: ::..:.. .:::..:. . : ::. .:.:. :..... .: ...: .: CCDS10 MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTV---INDSFQE 10 20 30 40 50 70 80 90 100 110 pF1KE6 W--LQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT . ::.:::::::: :. ...:.: ::: : .: :: .:.:.:... :::: ::.::: CCDS10 YSTLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYT 60 70 80 90 100 110 120 130 140 150 160 pF1KE6 VRHPEWH--------LNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE :. . : .. . :::..:::::::: ...::..:.:::::. CCDS10 DRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK 120 130 140 150 160 >>CCDS8660.1 EMP1 gene_id:2012|Hs108|chr12 (157 aa) initn: 409 init1: 194 opt: 426 Z-score: 541.1 bits: 106.3 E(32554): 8.1e-24 Smith-Waterman score: 426; 39.8% identity (77.0% similar) in 161 aa overlap (1-159:1-157) 10 20 30 40 50 pF1KE6 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGN--GHATDLWQNCSTSSSGNVHHCFSSSP ::.:: .:.:.:.:....::::::.. :.:.: .. ::.::.. : .. .: . CCDS86 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSD---SLSYAS 10 20 30 40 50 60 70 80 90 100 110 pF1KE6 NEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT .. :..::: ::::::: ...:..: ::::. ::.::...: .. ::.. ...::: CCDS86 EDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYT 60 70 80 90 100 110 120 130 140 150 160 pF1KE6 VRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE : . ...: .:..:::.:. : .... ::.:..:::. CCDS86 -SHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 120 130 140 150 160 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 28 14:05:25 2016 done: Mon Nov 28 14:05:25 2016 Total Scan time: 1.740 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]