FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE6679, 328 aa 1>>>pF1KE6679 328 - 328 aa - 328 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2675+/-0.000409; mu= 2.3651+/- 0.026 mean_var=375.3669+/-75.746, 0's: 0 Z-trim(123.2): 358 B-trim: 720 in 1/54 Lambda= 0.066198 statistics sampled from 43990 (44403) to 43990 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.481), width: 16 Scan time: 4.340 The best scores are: opt bits E(92320) NP_001842 (OMIM: 120210,614134,614135) collagen al ( 921) 2295 233.0 2e-60 XP_011533731 (OMIM: 120210,614134,614135) collagen ( 931) 2295 233.0 2e-60 XP_016865735 (OMIM: 120210,614134,614135) collagen ( 748) 1055 114.5 7.9e-25 NP_511040 (OMIM: 120210,614134,614135) collagen al ( 678) 473 58.8 4e-08 XP_011533732 (OMIM: 120210,614134,614135) collagen ( 688) 473 58.8 4e-08 XP_006710428 (OMIM: 120260,600204,614284) collagen ( 689) 355 47.6 0.0001 NP_001843 (OMIM: 120260,600204,614284) collagen al ( 689) 355 47.6 0.0001 XP_016855821 (OMIM: 120260,600204,614284) collagen ( 693) 355 47.6 0.0001 XP_016883155 (OMIM: 120270,600969,603932) collagen ( 486) 315 43.6 0.0011 XP_011526847 (OMIM: 120270,600969,603932) collagen ( 552) 315 43.6 0.0012 NP_001844 (OMIM: 120270,600969,603932) collagen al ( 684) 315 43.7 0.0014 XP_016867233 (OMIM: 608927) collagen alpha-1(XXVI) ( 311) 301 42.0 0.0022 XP_016867234 (OMIM: 608927) collagen alpha-1(XXVI) ( 311) 301 42.0 0.0022 XP_016867232 (OMIM: 608927) collagen alpha-1(XXVI) ( 429) 301 42.1 0.0027 NP_597714 (OMIM: 608927) collagen alpha-1(XXVI) ch ( 439) 301 42.2 0.0027 NP_001265492 (OMIM: 608927) collagen alpha-1(XXVI) ( 441) 301 42.2 0.0027 XP_011528177 (OMIM: 608926) EMI domain-containing ( 307) 291 41.0 0.0042 XP_016884078 (OMIM: 608926) EMI domain-containing ( 397) 293 41.3 0.0043 XP_011528176 (OMIM: 608926) EMI domain-containing ( 397) 293 41.3 0.0043 XP_011528175 (OMIM: 608926) EMI domain-containing ( 420) 293 41.4 0.0045 XP_011528174 (OMIM: 608926) EMI domain-containing ( 423) 293 41.4 0.0045 XP_011528172 (OMIM: 608926) EMI domain-containing ( 438) 293 41.4 0.0046 XP_011528171 (OMIM: 608926) EMI domain-containing ( 460) 293 41.4 0.0047 XP_011528170 (OMIM: 608926) EMI domain-containing ( 462) 293 41.4 0.0047 XP_011528173 (OMIM: 608926) EMI domain-containing ( 434) 291 41.2 0.0052 XP_011528178 (OMIM: 608926) EMI domain-containing ( 283) 284 40.3 0.0064 >>NP_001842 (OMIM: 120210,614134,614135) collagen alpha- (921 aa) initn: 2294 init1: 2294 opt: 2295 Z-score: 1206.4 bits: 233.0 E(92320): 2e-60 Smith-Waterman score: 2295; 99.1% identity (99.4% similar) in 330 aa overlap (1-328:1-330) 10 20 30 40 50 60 pF1KE6 MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE6 SQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE6 GSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE6 HKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE6 HCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP 250 260 270 280 290 300 310 320 pF1KE6 PGPPGPAGEPGKPGAPGKPGTPGAD--TSP ::::::::::::::::::::::::: :.: NP_001 PGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP 310 320 330 340 350 360 >>XP_011533731 (OMIM: 120210,614134,614135) collagen alp (931 aa) initn: 2294 init1: 2294 opt: 2295 Z-score: 1206.3 bits: 233.0 E(92320): 2e-60 Smith-Waterman score: 2295; 99.1% identity (99.4% similar) in 330 aa overlap (1-328:1-330) 10 20 30 40 50 60 pF1KE6 MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE6 SQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE6 GSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE6 HKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE6 HCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP 250 260 270 280 290 300 310 320 pF1KE6 PGPPGPAGEPGKPGAPGKPGTPGAD--TSP ::::::::::::::::::::::::: :.: XP_011 PGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP 310 320 330 340 350 360 >>XP_016865735 (OMIM: 120210,614134,614135) collagen alp (748 aa) initn: 1054 init1: 1054 opt: 1055 Z-score: 567.4 bits: 114.5 E(92320): 7.9e-25 Smith-Waterman score: 1055; 98.0% identity (98.6% similar) in 147 aa overlap (184-328:1-147) 160 170 180 190 200 210 pF1KE6 VFSYKGLDGSLQTAAFSNLSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPID :::::::::::::::::::::::::::::: XP_016 MIGVERSSATLFVDCNRIESLPIKPRGPID 10 20 30 220 230 240 250 260 270 pF1KE6 IDGFAVLGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPARITPSQTTDERGPPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDGFAVLGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPARITPSQTTDERGPPGE 40 50 60 70 80 90 280 290 300 310 320 pF1KE6 QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD--TSP :::::::::::::::::::::::::::::::::::::::::::::::::::: :.: XP_016 QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGS 100 110 120 130 140 150 XP_016 PGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPP 160 170 180 190 200 210 >>NP_511040 (OMIM: 120210,614134,614135) collagen alpha- (678 aa) initn: 472 init1: 472 opt: 473 Z-score: 267.4 bits: 58.8 E(92320): 4e-08 Smith-Waterman score: 473; 93.8% identity (96.9% similar) in 64 aa overlap (267-328:24-87) 240 250 260 270 280 290 pF1KE6 WMLIHCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRG .::::::::::::::::::::::::::::: NP_511 MAWTARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRG 10 20 30 40 50 300 310 320 pF1KE6 PKGPPGPPGPAGEPGKPGAPGKPGTPGAD--TSP ::::::::::::::::::::::::::::: :.: NP_511 PKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG 60 70 80 90 100 110 NP_511 RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP 120 130 140 150 160 170 >>XP_011533732 (OMIM: 120210,614134,614135) collagen alp (688 aa) initn: 472 init1: 472 opt: 473 Z-score: 267.4 bits: 58.8 E(92320): 4e-08 Smith-Waterman score: 473; 93.8% identity (96.9% similar) in 64 aa overlap (267-328:24-87) 240 250 260 270 280 290 pF1KE6 WMLIHCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRG .::::::::::::::::::::::::::::: XP_011 MAWTARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRG 10 20 30 40 50 300 310 320 pF1KE6 PKGPPGPPGPAGEPGKPGAPGKPGTPGAD--TSP ::::::::::::::::::::::::::::: :.: XP_011 PKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG 60 70 80 90 100 110 XP_011 RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP 120 130 140 150 160 170 >>XP_006710428 (OMIM: 120260,600204,614284) collagen alp (689 aa) initn: 809 init1: 355 opt: 355 Z-score: 206.5 bits: 47.6 E(92320): 0.0001 Smith-Waterman score: 355; 75.9% identity (77.6% similar) in 58 aa overlap (268-325:26-83) 240 250 260 270 280 290 pF1KE6 MLIHCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGP ::::::.::::::::::::: :::::: :: XP_006 MAAATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGP 10 20 30 40 50 300 310 320 pF1KE6 KGPPGPPGPAGEPGKPGAPGKPGTPGADTSP : ::::: ::::: : : : :: : XP_006 PGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP 60 70 80 90 100 110 >>NP_001843 (OMIM: 120260,600204,614284) collagen alpha- (689 aa) initn: 809 init1: 355 opt: 355 Z-score: 206.5 bits: 47.6 E(92320): 0.0001 Smith-Waterman score: 355; 75.9% identity (77.6% similar) in 58 aa overlap (268-325:26-83) 240 250 260 270 280 290 pF1KE6 MLIHCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGP ::::::.::::::::::::: :::::: :: NP_001 MAAATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGP 10 20 30 40 50 300 310 320 pF1KE6 KGPPGPPGPAGEPGKPGAPGKPGTPGADTSP : ::::: ::::: : : : :: : NP_001 PGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP 60 70 80 90 100 110 >>XP_016855821 (OMIM: 120260,600204,614284) collagen alp (693 aa) initn: 809 init1: 355 opt: 355 Z-score: 206.4 bits: 47.6 E(92320): 0.0001 Smith-Waterman score: 355; 75.9% identity (77.6% similar) in 58 aa overlap (268-325:26-83) 240 250 260 270 280 290 pF1KE6 MLIHCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGP ::::::.::::::::::::: :::::: :: XP_016 MAAATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGP 10 20 30 40 50 300 310 320 pF1KE6 KGPPGPPGPAGEPGKPGAPGKPGTPGADTSP : ::::: ::::: : : : :: : XP_016 PGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP 60 70 80 90 100 110 >>XP_016883155 (OMIM: 120270,600969,603932) collagen alp (486 aa) initn: 808 init1: 312 opt: 315 Z-score: 187.5 bits: 43.6 E(92320): 0.0011 Smith-Waterman score: 315; 70.2% identity (75.4% similar) in 57 aa overlap (272-325:29-85) 250 260 270 280 290 300 pF1KE6 CDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPP : :::::::::: :: :::::. :: : : XP_016 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP 10 20 30 40 50 310 320 pF1KE6 GPPGPAGEPGKPGAPGK---PGTPGADTSP ::::: : ::::: ::. :: ::.: XP_016 GPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKG 60 70 80 90 100 110 >>XP_011526847 (OMIM: 120270,600969,603932) collagen alp (552 aa) initn: 1029 init1: 312 opt: 315 Z-score: 186.9 bits: 43.6 E(92320): 0.0012 Smith-Waterman score: 315; 70.2% identity (75.4% similar) in 57 aa overlap (272-325:29-85) 250 260 270 280 290 300 pF1KE6 CDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPP : :::::::::: :: :::::. :: : : XP_011 MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLP 10 20 30 40 50 310 320 pF1KE6 GPPGPAGEPGKPGAPGK---PGTPGADTSP ::::: : ::::: ::. :: ::.: XP_011 GPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKG 60 70 80 90 100 110 328 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:35:16 2019 done: Thu Oct 24 21:35:17 2019 Total Scan time: 4.340 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]