FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE9260, 1582 aa 1>>>pF1KE9260 1582 - 1582 aa - 1582 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3034+/-0.00125; mu= 8.5741+/- 0.076 mean_var=277.4263+/-54.675, 0's: 0 Z-trim(110.8): 51 B-trim: 109 in 1/49 Lambda= 0.077002 statistics sampled from 11879 (11908) to 11879 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.366), width: 16 Scan time: 6.170 The best scores are: opt bits E(32554) CCDS43099.1 PBRM1 gene_id:55193|Hs108|chr3 (1582) 7392 836.2 0 >>CCDS43099.1 PBRM1 gene_id:55193|Hs108|chr3 (1582 aa) initn: 7103 init1: 7103 opt: 7392 Z-score: 4449.6 bits: 836.2 E(32554): 0 Smith-Waterman score: 9963; 93.6% identity (93.6% similar) in 1634 aa overlap (1-1582:1-1582) 10 20 30 40 50 60 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS :::::::::::::::::::::::::::: ::::::: CCDS43 GDYVYVEPAEANLQPHIVCIERLWEDSA-------------------------EKEVFKS 970 980 990 1030 1040 1050 1060 1070 1080 pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK ::::::::::::::: :::::::::::::::::: CCDS43 GGDDDIEEMGEEDSE---------------------------STPKSAKGSAKKEGSKRK 1300 1310 1320 1390 1400 1410 1420 1430 pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEG---------- :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP 1330 1340 1350 1360 1370 1380 1440 pF1KE9 ------------------------------------------VMNQGVAPMVGTPAPGGS :::::::::::::::::: CCDS43 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE9 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE9 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR 1510 1520 1530 1540 1550 1560 1570 1580 pF1KE9 DTLNIRQAYNLENV :::::::::::::: CCDS43 DTLNIRQAYNLENV 1570 1580 1582 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Feb 10 14:59:42 2017 done: Fri Feb 10 14:59:43 2017 Total Scan time: 6.170 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]