FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE9260, 1582 aa 1>>>pF1KE9260 1582 - 1582 aa - 1582 aa Library: /omim/omim.rfq.tfa 61265892 residues in 86068 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.7107+/-0.000504; mu= 6.6133+/- 0.032 mean_var=336.4370+/-68.648, 0's: 0 Z-trim(118.8): 94 B-trim: 408 in 2/52 Lambda= 0.069923 statistics sampled from 32112 (32210) to 32112 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.374), width: 16 Scan time: 19.970 The best scores are: opt bits E(86068) NP_851385 (OMIM: 606083) protein polybromo-1 isofo (1582) 10581 1083.0 0 XP_016862253 (OMIM: 606083) PREDICTED: protein pol (1603) 10581 1083.0 0 XP_016862247 (OMIM: 606083) PREDICTED: protein pol (1634) 9634 987.5 0 XP_016862246 (OMIM: 606083) PREDICTED: protein pol (1634) 9634 987.5 0 XP_016862244 (OMIM: 606083) PREDICTED: protein pol (1655) 9634 987.5 0 XP_016862245 (OMIM: 606083) PREDICTED: protein pol (1654) 9616 985.7 0 XP_016862237 (OMIM: 606083) PREDICTED: protein pol (1689) 9538 977.8 0 XP_016862238 (OMIM: 606083) PREDICTED: protein pol (1689) 9538 977.8 0 XP_016862239 (OMIM: 606083) PREDICTED: protein pol (1689) 9538 977.8 0 XP_016862233 (OMIM: 606083) PREDICTED: protein pol (1707) 9538 977.8 0 XP_016862231 (OMIM: 606083) PREDICTED: protein pol (1710) 9538 977.8 0 XP_016862230 (OMIM: 606083) PREDICTED: protein pol (1710) 9538 977.8 0 XP_016862224 (OMIM: 606083) PREDICTED: protein pol (1719) 8363 859.3 0 XP_016862225 (OMIM: 606083) PREDICTED: protein pol (1718) 8345 857.5 0 NP_060783 (OMIM: 606083) protein polybromo-1 isofo (1582) 7392 761.3 1.4e-218 XP_016862236 (OMIM: 606083) PREDICTED: protein pol (1702) 7320 754.1 2.3e-216 XP_016862252 (OMIM: 606083) PREDICTED: protein pol (1615) 7228 744.8 1.4e-213 XP_016862250 (OMIM: 606083) PREDICTED: protein pol (1618) 7228 744.8 1.4e-213 XP_016862249 (OMIM: 606083) PREDICTED: protein pol (1618) 7228 744.8 1.4e-213 XP_016862251 (OMIM: 606083) PREDICTED: protein pol (1617) 7220 744.0 2.4e-213 XP_016862255 (OMIM: 606083) PREDICTED: protein pol (1578) 6522 673.5 3.7e-192 XP_016862248 (OMIM: 606083) PREDICTED: protein pol (1630) 6522 673.6 3.8e-192 XP_016862240 (OMIM: 606083) PREDICTED: protein pol (1685) 6522 673.6 3.9e-192 XP_016862242 (OMIM: 606083) PREDICTED: protein pol (1679) 6281 649.3 8.1e-185 XP_016862243 (OMIM: 606083) PREDICTED: protein pol (1673) 6193 640.4 3.8e-182 XP_016862241 (OMIM: 606083) PREDICTED: protein pol (1682) 6193 640.4 3.8e-182 XP_016862234 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182 XP_016862235 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182 XP_005265336 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182 XP_005265340 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182 XP_005265337 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182 XP_005265339 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182 XP_016862227 (OMIM: 606083) PREDICTED: protein pol (1713) 6185 639.6 6.8e-182 XP_016862226 (OMIM: 606083) PREDICTED: protein pol (1713) 6185 639.6 6.8e-182 XP_016862229 (OMIM: 606083) PREDICTED: protein pol (1713) 6185 639.6 6.8e-182 XP_016862228 (OMIM: 606083) PREDICTED: protein pol (1713) 6185 639.6 6.8e-182 XP_016862223 (OMIM: 606083) PREDICTED: protein pol (1721) 6185 639.6 6.8e-182 XP_016862222 (OMIM: 606083) PREDICTED: protein pol (1721) 6185 639.6 6.8e-182 XP_011532204 (OMIM: 606083) PREDICTED: protein pol (1725) 6185 639.6 6.8e-182 XP_011532202 (OMIM: 606083) PREDICTED: protein pol (1725) 6185 639.6 6.8e-182 XP_011532205 (OMIM: 606083) PREDICTED: protein pol (1725) 6185 639.6 6.8e-182 XP_016862220 (OMIM: 606083) PREDICTED: protein pol (1731) 6185 639.6 6.8e-182 XP_016862219 (OMIM: 606083) PREDICTED: protein pol (1731) 6185 639.6 6.8e-182 XP_016862217 (OMIM: 606083) PREDICTED: protein pol (1734) 6185 639.6 6.8e-182 XP_016862214 (OMIM: 606083) PREDICTED: protein pol (1734) 6185 639.6 6.8e-182 XP_016862216 (OMIM: 606083) PREDICTED: protein pol (1734) 6185 639.6 6.8e-182 XP_016862215 (OMIM: 606083) PREDICTED: protein pol (1734) 6185 639.6 6.8e-182 XP_016862221 (OMIM: 606083) PREDICTED: protein pol (1724) 6177 638.8 1.2e-181 XP_016862218 (OMIM: 606083) PREDICTED: protein pol (1733) 6177 638.8 1.2e-181 XP_016862232 (OMIM: 606083) PREDICTED: protein pol (1709) 3169 335.3 2.6e-90 >>NP_851385 (OMIM: 606083) protein polybromo-1 isoform 4 (1582 aa) initn: 10581 init1: 10581 opt: 10581 Z-score: 5783.7 bits: 1083.0 E(86068): 0 Smith-Waterman score: 10581; 100.0% identity (100.0% similar) in 1582 aa overlap (1-1582:1-1582) 10 20 30 40 50 60 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE9 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHS 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE9 EAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_851 EAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALW 1510 1520 1530 1540 1550 1560 1570 1580 pF1KE9 RLRDLMLRDTLNIRQAYNLENV :::::::::::::::::::::: NP_851 RLRDLMLRDTLNIRQAYNLENV 1570 1580 >>XP_016862253 (OMIM: 606083) PREDICTED: protein polybro (1603 aa) initn: 10581 init1: 10581 opt: 10581 Z-score: 5783.6 bits: 1083.0 E(86068): 0 Smith-Waterman score: 10581; 100.0% identity (100.0% similar) in 1582 aa overlap (1-1582:22-1603) 10 20 30 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS ::::::::::::::::::::::::::::::::::::::: XP_016 MRRLAFRGAGCALVKLKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE9 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE9 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE9 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE9 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE9 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE9 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE9 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE9 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE9 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 550 560 570 580 590 600 580 590 600 610 620 630 pF1KE9 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 610 620 630 640 650 660 640 650 660 670 680 690 pF1KE9 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT 670 680 690 700 710 720 700 710 720 730 740 750 pF1KE9 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 730 740 750 760 770 780 760 770 780 790 800 810 pF1KE9 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP 790 800 810 820 830 840 820 830 840 850 860 870 pF1KE9 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL 850 860 870 880 890 900 880 890 900 910 920 930 pF1KE9 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG 910 920 930 940 950 960 940 950 960 970 980 990 pF1KE9 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KE9 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KE9 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KE9 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KE9 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KE9 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KE9 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KE9 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KE9 LETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVI 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KE9 QQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQES 1510 1520 1530 1540 1550 1560 1540 1550 1560 1570 1580 pF1KE9 RLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV ::::::::::::::::::::::::::::::::::::::::::: XP_016 RLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV 1570 1580 1590 1600 >>XP_016862247 (OMIM: 606083) PREDICTED: protein polybro (1634 aa) initn: 9543 init1: 9543 opt: 9634 Z-score: 5267.3 bits: 987.5 E(86068): 0 Smith-Waterman score: 10341; 96.8% identity (96.8% similar) in 1614 aa overlap (1-1562:1-1614) 10 20 30 40 50 60 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEG---------- :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP 1390 1400 1410 1420 1430 1440 1440 pF1KE9 ------------------------------------------VMNQGVAPMVGTPAPGGS :::::::::::::::::: XP_016 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS 1450 1460 1470 1480 1490 1500 1450 1460 1470 1480 1490 1500 pF1KE9 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE 1510 1520 1530 1540 1550 1560 1510 1520 1530 1540 1550 1560 pF1KE9 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR 1570 1580 1590 1600 1610 1620 1570 1580 pF1KE9 DTLNIRQAYNLENV XP_016 DTLNIRQAYNLENV 1630 >>XP_016862246 (OMIM: 606083) PREDICTED: protein polybro (1634 aa) initn: 9543 init1: 9543 opt: 9634 Z-score: 5267.3 bits: 987.5 E(86068): 0 Smith-Waterman score: 10341; 96.8% identity (96.8% similar) in 1614 aa overlap (1-1562:1-1614) 10 20 30 40 50 60 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEG---------- :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP 1390 1400 1410 1420 1430 1440 1440 pF1KE9 ------------------------------------------VMNQGVAPMVGTPAPGGS :::::::::::::::::: XP_016 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS 1450 1460 1470 1480 1490 1500 1450 1460 1470 1480 1490 1500 pF1KE9 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE 1510 1520 1530 1540 1550 1560 1510 1520 1530 1540 1550 1560 pF1KE9 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR 1570 1580 1590 1600 1610 1620 1570 1580 pF1KE9 DTLNIRQAYNLENV XP_016 DTLNIRQAYNLENV 1630 >>XP_016862244 (OMIM: 606083) PREDICTED: protein polybro (1655 aa) initn: 9543 init1: 9543 opt: 9634 Z-score: 5267.2 bits: 987.5 E(86068): 0 Smith-Waterman score: 10341; 96.8% identity (96.8% similar) in 1614 aa overlap (1-1562:22-1635) 10 20 30 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS ::::::::::::::::::::::::::::::::::::::: XP_016 MRRLAFRGAGCALVKLKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE9 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE9 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE9 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE9 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE9 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE9 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE9 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE9 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE9 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 550 560 570 580 590 600 580 590 600 610 620 630 pF1KE9 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 610 620 630 640 650 660 640 650 660 670 680 690 pF1KE9 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT 670 680 690 700 710 720 700 710 720 730 740 750 pF1KE9 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 730 740 750 760 770 780 760 770 780 790 800 810 pF1KE9 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP 790 800 810 820 830 840 820 830 840 850 860 870 pF1KE9 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL 850 860 870 880 890 900 880 890 900 910 920 930 pF1KE9 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG 910 920 930 940 950 960 940 950 960 970 980 990 pF1KE9 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KE9 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KE9 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KE9 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KE9 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KE9 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KE9 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KE9 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN 1390 1400 1410 1420 1430 1440 1420 1430 pF1KE9 LETAKKAEYEG------------------------------------------------- ::::::::::: XP_016 LETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIP 1450 1460 1470 1480 1490 1500 1440 1450 1460 1470 1480 pF1KE9 ---VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMF ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMF 1510 1520 1530 1540 1550 1560 1490 1500 1510 1520 1530 1540 pF1KE9 VAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK 1570 1580 1590 1600 1610 1620 1550 1560 1570 1580 pF1KE9 SKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV ::::::::::::::: XP_016 SKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV 1630 1640 1650 >>XP_016862245 (OMIM: 606083) PREDICTED: protein polybro (1654 aa) initn: 7148 init1: 6098 opt: 9616 Z-score: 5257.4 bits: 985.7 E(86068): 0 Smith-Waterman score: 10330; 96.7% identity (96.7% similar) in 1615 aa overlap (1-1563:22-1635) 10 20 30 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS ::::::::::::::::::::::::::::::::::::::: XP_016 MRRLAFRGAGCALVKLKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE9 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE9 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE9 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE9 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE9 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE9 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE9 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE9 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE9 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 550 560 570 580 590 600 580 590 600 610 620 630 pF1KE9 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 610 620 630 640 650 660 640 650 660 670 680 690 pF1KE9 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT 670 680 690 700 710 720 700 710 720 730 740 750 pF1KE9 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 730 740 750 760 770 780 760 770 780 790 800 810 pF1KE9 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP 790 800 810 820 830 840 820 830 840 850 860 870 pF1KE9 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL 850 860 870 880 890 900 880 890 900 910 920 930 pF1KE9 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_016 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKR-AEKSEDSSGAAG 910 920 930 940 950 940 950 960 970 980 990 pF1KE9 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY 960 970 980 990 1000 1010 1000 1010 1020 1030 1040 1050 pF1KE9 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC 1020 1030 1040 1050 1060 1070 1060 1070 1080 1090 1100 1110 pF1KE9 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS 1080 1090 1100 1110 1120 1130 1120 1130 1140 1150 1160 1170 pF1KE9 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI 1140 1150 1160 1170 1180 1190 1180 1190 1200 1210 1220 1230 pF1KE9 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK 1200 1210 1220 1230 1240 1250 1240 1250 1260 1270 1280 1290 pF1KE9 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK 1260 1270 1280 1290 1300 1310 1300 1310 1320 1330 1340 1350 pF1KE9 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT 1320 1330 1340 1350 1360 1370 1360 1370 1380 1390 1400 1410 pF1KE9 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN 1380 1390 1400 1410 1420 1430 1420 1430 pF1KE9 LETAKKAEYEG------------------------------------------------- ::::::::::: XP_016 LETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIP 1440 1450 1460 1470 1480 1490 1440 1450 1460 1470 1480 pF1KE9 ---VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMF ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMF 1500 1510 1520 1530 1540 1550 1490 1500 1510 1520 1530 1540 pF1KE9 VAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK 1560 1570 1580 1590 1600 1610 1550 1560 1570 1580 pF1KE9 SKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV :::::::::::::::: XP_016 SKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV 1620 1630 1640 1650 >>XP_016862237 (OMIM: 606083) PREDICTED: protein polybro (1689 aa) initn: 10567 init1: 9517 opt: 9538 Z-score: 5214.7 bits: 977.8 E(86068): 0 Smith-Waterman score: 9865; 93.4% identity (93.4% similar) in 1614 aa overlap (1-1507:1-1614) 10 20 30 40 50 60 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE 1390 1400 1410 1420 1430 1440 pF1KE9 ------------------------------------------------------------ XP_016 RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGP 1450 1460 1470 1480 1490 1500 1430 1440 1450 pF1KE9 ------------------------------------GVMNQGVAPMVGTPAPGGSPYGQQ :::::::::::::::::::::::: XP_016 VDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQ 1510 1520 1530 1540 1550 1560 1460 1470 1480 1490 1500 1510 pF1KE9 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE 1570 1580 1590 1600 1610 1620 1520 1530 1540 1550 1560 1570 pF1KE9 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI XP_016 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI 1630 1640 1650 1660 1670 1680 >-- initn: 492 init1: 492 opt: 492 Z-score: 282.9 bits: 65.3 E(86068): 5.1e-09 Smith-Waterman score: 492; 100.0% identity (100.0% similar) in 75 aa overlap (1508-1582:1615-1689) 1480 1490 1500 1510 1520 1530 pF1KE9 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ :::::::::::::::::::::::::::::: XP_016 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ 1590 1600 1610 1620 1630 1640 1540 1550 1560 1570 1580 pF1KE9 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV 1650 1660 1670 1680 >>XP_016862238 (OMIM: 606083) PREDICTED: protein polybro (1689 aa) initn: 10567 init1: 9517 opt: 9538 Z-score: 5214.7 bits: 977.8 E(86068): 0 Smith-Waterman score: 9865; 93.4% identity (93.4% similar) in 1614 aa overlap (1-1507:1-1614) 10 20 30 40 50 60 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE 1390 1400 1410 1420 1430 1440 pF1KE9 ------------------------------------------------------------ XP_016 RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGP 1450 1460 1470 1480 1490 1500 1430 1440 1450 pF1KE9 ------------------------------------GVMNQGVAPMVGTPAPGGSPYGQQ :::::::::::::::::::::::: XP_016 VDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQ 1510 1520 1530 1540 1550 1560 1460 1470 1480 1490 1500 1510 pF1KE9 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE 1570 1580 1590 1600 1610 1620 1520 1530 1540 1550 1560 1570 pF1KE9 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI XP_016 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI 1630 1640 1650 1660 1670 1680 >-- initn: 492 init1: 492 opt: 492 Z-score: 282.9 bits: 65.3 E(86068): 5.1e-09 Smith-Waterman score: 492; 100.0% identity (100.0% similar) in 75 aa overlap (1508-1582:1615-1689) 1480 1490 1500 1510 1520 1530 pF1KE9 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ :::::::::::::::::::::::::::::: XP_016 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ 1590 1600 1610 1620 1630 1640 1540 1550 1560 1570 1580 pF1KE9 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV 1650 1660 1670 1680 >>XP_016862239 (OMIM: 606083) PREDICTED: protein polybro (1689 aa) initn: 10567 init1: 9517 opt: 9538 Z-score: 5214.7 bits: 977.8 E(86068): 0 Smith-Waterman score: 9865; 93.4% identity (93.4% similar) in 1614 aa overlap (1-1507:1-1614) 10 20 30 40 50 60 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE 1390 1400 1410 1420 1430 1440 pF1KE9 ------------------------------------------------------------ XP_016 RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGP 1450 1460 1470 1480 1490 1500 1430 1440 1450 pF1KE9 ------------------------------------GVMNQGVAPMVGTPAPGGSPYGQQ :::::::::::::::::::::::: XP_016 VDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQ 1510 1520 1530 1540 1550 1560 1460 1470 1480 1490 1500 1510 pF1KE9 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE 1570 1580 1590 1600 1610 1620 1520 1530 1540 1550 1560 1570 pF1KE9 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI XP_016 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI 1630 1640 1650 1660 1670 1680 >-- initn: 492 init1: 492 opt: 492 Z-score: 282.9 bits: 65.3 E(86068): 5.1e-09 Smith-Waterman score: 492; 100.0% identity (100.0% similar) in 75 aa overlap (1508-1582:1615-1689) 1480 1490 1500 1510 1520 1530 pF1KE9 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ :::::::::::::::::::::::::::::: XP_016 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ 1590 1600 1610 1620 1630 1640 1540 1550 1560 1570 1580 pF1KE9 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV 1650 1660 1670 1680 >>XP_016862233 (OMIM: 606083) PREDICTED: protein polybro (1707 aa) initn: 10567 init1: 9517 opt: 9538 Z-score: 5214.7 bits: 977.8 E(86068): 0 Smith-Waterman score: 9865; 93.4% identity (93.4% similar) in 1614 aa overlap (1-1507:19-1632) 10 20 30 40 pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLP :::::::::::::::::::::::::::::::::::::::::: XP_016 MRRLAFRGAGCALKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE9 TVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLK 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE9 MEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDD 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE9 DEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYA 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE9 IIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYM 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE9 KKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRL 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE9 SAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQ 370 380 390 400 410 420 410 420 430 440 450 460 pF1KE9 LIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRY 430 440 450 460 470 480 470 480 490 500 510 520 pF1KE9 NVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQR 490 500 510 520 530 540 530 540 550 560 570 580 pF1KE9 MKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAG 550 560 570 580 590 600 590 600 610 620 630 640 pF1KE9 EEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLS 610 620 630 640 650 660 650 660 670 680 690 700 pF1KE9 RKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKK 670 680 690 700 710 720 710 720 730 740 750 760 pF1KE9 PMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRD 730 740 750 760 770 780 770 780 790 800 810 820 pF1KE9 LEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTF 790 800 810 820 830 840 830 840 850 860 870 880 pF1KE9 DIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKN 850 860 870 880 890 900 890 900 910 920 930 940 pF1KE9 GEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSG 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KE9 LHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPN 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KE9 ETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESR 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KE9 YSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAE 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KE9 DNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKV 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KE9 WVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFL 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KE9 SCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPS 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KE9 PLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQ 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KE9 STPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLET 1390 1400 1410 1420 1430 1440 pF1KE9 AKKAEYE----------------------------------------------------- ::::::: XP_016 AKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTP 1450 1460 1470 1480 1490 1500 1430 pF1KE9 ------------------------------------------------------GVMNQG :::::: XP_016 VAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQG 1510 1520 1530 1540 1550 1560 1440 1450 1460 1470 1480 1490 pF1KE9 VAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQ 1570 1580 1590 1600 1610 1620 1500 1510 1520 1530 1540 1550 pF1KE9 RLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTM :::::::::::: XP_016 RLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTM 1630 1640 1650 1660 1670 1680 >-- initn: 492 init1: 492 opt: 492 Z-score: 282.9 bits: 65.3 E(86068): 5.2e-09 Smith-Waterman score: 492; 100.0% identity (100.0% similar) in 75 aa overlap (1508-1582:1633-1707) 1480 1490 1500 1510 1520 1530 pF1KE9 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ :::::::::::::::::::::::::::::: XP_016 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ 1610 1620 1630 1640 1650 1660 1540 1550 1560 1570 1580 pF1KE9 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV 1670 1680 1690 1700 1582 residues in 1 query sequences 61265892 residues in 86068 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Feb 10 14:59:44 2017 done: Fri Feb 10 14:59:47 2017 Total Scan time: 19.970 Total Display time: 0.670 Function used was FASTA [36.3.4 Apr, 2011]