Result of FASTA (omim) for pF1KE9260
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9260, 1582 aa
  1>>>pF1KE9260     1582 - 1582 aa - 1582 aa
Library: /omim/omim.rfq.tfa
  61265892 residues in 86068 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.7107+/-0.000504; mu= 6.6133+/- 0.032
 mean_var=336.4370+/-68.648, 0's: 0 Z-trim(118.8): 94  B-trim: 408 in 2/52
 Lambda= 0.069923
 statistics sampled from 32112 (32210) to 32112 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.374), width:  16
 Scan time: 19.970

The best scores are:                                      opt bits E(86068)
NP_851385 (OMIM: 606083) protein polybromo-1 isofo (1582) 10581 1083.0       0
XP_016862253 (OMIM: 606083) PREDICTED: protein pol (1603) 10581 1083.0       0
XP_016862247 (OMIM: 606083) PREDICTED: protein pol (1634) 9634 987.5       0
XP_016862246 (OMIM: 606083) PREDICTED: protein pol (1634) 9634 987.5       0
XP_016862244 (OMIM: 606083) PREDICTED: protein pol (1655) 9634 987.5       0
XP_016862245 (OMIM: 606083) PREDICTED: protein pol (1654) 9616 985.7       0
XP_016862237 (OMIM: 606083) PREDICTED: protein pol (1689) 9538 977.8       0
XP_016862238 (OMIM: 606083) PREDICTED: protein pol (1689) 9538 977.8       0
XP_016862239 (OMIM: 606083) PREDICTED: protein pol (1689) 9538 977.8       0
XP_016862233 (OMIM: 606083) PREDICTED: protein pol (1707) 9538 977.8       0
XP_016862231 (OMIM: 606083) PREDICTED: protein pol (1710) 9538 977.8       0
XP_016862230 (OMIM: 606083) PREDICTED: protein pol (1710) 9538 977.8       0
XP_016862224 (OMIM: 606083) PREDICTED: protein pol (1719) 8363 859.3       0
XP_016862225 (OMIM: 606083) PREDICTED: protein pol (1718) 8345 857.5       0
NP_060783 (OMIM: 606083) protein polybromo-1 isofo (1582) 7392 761.3 1.4e-218
XP_016862236 (OMIM: 606083) PREDICTED: protein pol (1702) 7320 754.1 2.3e-216
XP_016862252 (OMIM: 606083) PREDICTED: protein pol (1615) 7228 744.8 1.4e-213
XP_016862250 (OMIM: 606083) PREDICTED: protein pol (1618) 7228 744.8 1.4e-213
XP_016862249 (OMIM: 606083) PREDICTED: protein pol (1618) 7228 744.8 1.4e-213
XP_016862251 (OMIM: 606083) PREDICTED: protein pol (1617) 7220 744.0 2.4e-213
XP_016862255 (OMIM: 606083) PREDICTED: protein pol (1578) 6522 673.5 3.7e-192
XP_016862248 (OMIM: 606083) PREDICTED: protein pol (1630) 6522 673.6 3.8e-192
XP_016862240 (OMIM: 606083) PREDICTED: protein pol (1685) 6522 673.6 3.9e-192
XP_016862242 (OMIM: 606083) PREDICTED: protein pol (1679) 6281 649.3 8.1e-185
XP_016862243 (OMIM: 606083) PREDICTED: protein pol (1673) 6193 640.4 3.8e-182
XP_016862241 (OMIM: 606083) PREDICTED: protein pol (1682) 6193 640.4 3.8e-182
XP_016862234 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182
XP_016862235 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182
XP_005265336 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182
XP_005265340 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182
XP_005265337 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182
XP_005265339 (OMIM: 606083) PREDICTED: protein pol (1704) 6185 639.6 6.8e-182
XP_016862227 (OMIM: 606083) PREDICTED: protein pol (1713) 6185 639.6 6.8e-182
XP_016862226 (OMIM: 606083) PREDICTED: protein pol (1713) 6185 639.6 6.8e-182
XP_016862229 (OMIM: 606083) PREDICTED: protein pol (1713) 6185 639.6 6.8e-182
XP_016862228 (OMIM: 606083) PREDICTED: protein pol (1713) 6185 639.6 6.8e-182
XP_016862223 (OMIM: 606083) PREDICTED: protein pol (1721) 6185 639.6 6.8e-182
XP_016862222 (OMIM: 606083) PREDICTED: protein pol (1721) 6185 639.6 6.8e-182
XP_011532204 (OMIM: 606083) PREDICTED: protein pol (1725) 6185 639.6 6.8e-182
XP_011532202 (OMIM: 606083) PREDICTED: protein pol (1725) 6185 639.6 6.8e-182
XP_011532205 (OMIM: 606083) PREDICTED: protein pol (1725) 6185 639.6 6.8e-182
XP_016862220 (OMIM: 606083) PREDICTED: protein pol (1731) 6185 639.6 6.8e-182
XP_016862219 (OMIM: 606083) PREDICTED: protein pol (1731) 6185 639.6 6.8e-182
XP_016862217 (OMIM: 606083) PREDICTED: protein pol (1734) 6185 639.6 6.8e-182
XP_016862214 (OMIM: 606083) PREDICTED: protein pol (1734) 6185 639.6 6.8e-182
XP_016862216 (OMIM: 606083) PREDICTED: protein pol (1734) 6185 639.6 6.8e-182
XP_016862215 (OMIM: 606083) PREDICTED: protein pol (1734) 6185 639.6 6.8e-182
XP_016862221 (OMIM: 606083) PREDICTED: protein pol (1724) 6177 638.8 1.2e-181
XP_016862218 (OMIM: 606083) PREDICTED: protein pol (1733) 6177 638.8 1.2e-181
XP_016862232 (OMIM: 606083) PREDICTED: protein pol (1709) 3169 335.3 2.6e-90


>>NP_851385 (OMIM: 606083) protein polybromo-1 isoform 4  (1582 aa)
 initn: 10581 init1: 10581 opt: 10581  Z-score: 5783.7  bits: 1083.0 E(86068):    0
Smith-Waterman score: 10581; 100.0% identity (100.0% similar) in 1582 aa overlap (1-1582:1-1582)

               10        20        30        40        50        60
pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMV
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE9 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHS
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE9 EAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 EAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALW
             1510      1520      1530      1540      1550      1560

             1570      1580  
pF1KE9 RLRDLMLRDTLNIRQAYNLENV
       ::::::::::::::::::::::
NP_851 RLRDLMLRDTLNIRQAYNLENV
             1570      1580  

>>XP_016862253 (OMIM: 606083) PREDICTED: protein polybro  (1603 aa)
 initn: 10581 init1: 10581 opt: 10581  Z-score: 5783.6  bits: 1083.0 E(86068):    0
Smith-Waterman score: 10581; 100.0% identity (100.0% similar) in 1582 aa overlap (1-1582:22-1603)

                                    10        20        30         
pF1KE9                      MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS
                            :::::::::::::::::::::::::::::::::::::::
XP_016 MRRLAFRGAGCALVKLKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS
               10        20        30        40        50        60

      40        50        60        70        80        90         
pF1KE9 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ
               70        80        90       100       110       120

     100       110       120       130       140       150         
pF1KE9 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD
              130       140       150       160       170       180

     160       170       180       190       200       210         
pF1KE9 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD
              190       200       210       220       230       240

     220       230       240       250       260       270         
pF1KE9 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI
              250       260       270       280       290       300

     280       290       300       310       320       330         
pF1KE9 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG
              310       320       330       340       350       360

     340       350       360       370       380       390         
pF1KE9 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN
              370       380       390       400       410       420

     400       410       420       430       440       450         
pF1KE9 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA
              430       440       450       460       470       480

     460       470       480       490       500       510         
pF1KE9 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR
              490       500       510       520       530       540

     520       530       540       550       560       570         
pF1KE9 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK
              550       560       570       580       590       600

     580       590       600       610       620       630         
pF1KE9 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL
              610       620       630       640       650       660

     640       650       660       670       680       690         
pF1KE9 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT
              670       680       690       700       710       720

     700       710       720       730       740       750         
pF1KE9 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET
              730       740       750       760       770       780

     760       770       780       790       800       810         
pF1KE9 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP
              790       800       810       820       830       840

     820       830       840       850       860       870         
pF1KE9 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL
              850       860       870       880       890       900

     880       890       900       910       920       930         
pF1KE9 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG
              910       920       930       940       950       960

     940       950       960       970       980       990         
pF1KE9 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY
              970       980       990      1000      1010      1020

    1000      1010      1020      1030      1040      1050         
pF1KE9 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC
             1030      1040      1050      1060      1070      1080

    1060      1070      1080      1090      1100      1110         
pF1KE9 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS
             1090      1100      1110      1120      1130      1140

    1120      1130      1140      1150      1160      1170         
pF1KE9 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI
             1150      1160      1170      1180      1190      1200

    1180      1190      1200      1210      1220      1230         
pF1KE9 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK
             1210      1220      1230      1240      1250      1260

    1240      1250      1260      1270      1280      1290         
pF1KE9 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK
             1270      1280      1290      1300      1310      1320

    1300      1310      1320      1330      1340      1350         
pF1KE9 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT
             1330      1340      1350      1360      1370      1380

    1360      1370      1380      1390      1400      1410         
pF1KE9 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN
             1390      1400      1410      1420      1430      1440

    1420      1430      1440      1450      1460      1470         
pF1KE9 LETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVI
             1450      1460      1470      1480      1490      1500

    1480      1490      1500      1510      1520      1530         
pF1KE9 QQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQES
             1510      1520      1530      1540      1550      1560

    1540      1550      1560      1570      1580  
pF1KE9 RLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
       :::::::::::::::::::::::::::::::::::::::::::
XP_016 RLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
             1570      1580      1590      1600   

>>XP_016862247 (OMIM: 606083) PREDICTED: protein polybro  (1634 aa)
 initn: 9543 init1: 9543 opt: 9634  Z-score: 5267.3  bits: 987.5 E(86068):    0
Smith-Waterman score: 10341; 96.8% identity (96.8% similar) in 1614 aa overlap (1-1562:1-1614)

               10        20        30        40        50        60
pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430          
pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEG----------
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP
             1390      1400      1410      1420      1430      1440

                                                       1440        
pF1KE9 ------------------------------------------VMNQGVAPMVGTPAPGGS
                                                 ::::::::::::::::::
XP_016 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS
             1450      1460      1470      1480      1490      1500

     1450      1460      1470      1480      1490      1500        
pF1KE9 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE
             1510      1520      1530      1540      1550      1560

     1510      1520      1530      1540      1550      1560        
pF1KE9 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR
             1570      1580      1590      1600      1610      1620

     1570      1580  
pF1KE9 DTLNIRQAYNLENV
                     
XP_016 DTLNIRQAYNLENV
             1630    

>>XP_016862246 (OMIM: 606083) PREDICTED: protein polybro  (1634 aa)
 initn: 9543 init1: 9543 opt: 9634  Z-score: 5267.3  bits: 987.5 E(86068):    0
Smith-Waterman score: 10341; 96.8% identity (96.8% similar) in 1614 aa overlap (1-1562:1-1614)

               10        20        30        40        50        60
pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430          
pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEG----------
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP
             1390      1400      1410      1420      1430      1440

                                                       1440        
pF1KE9 ------------------------------------------VMNQGVAPMVGTPAPGGS
                                                 ::::::::::::::::::
XP_016 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS
             1450      1460      1470      1480      1490      1500

     1450      1460      1470      1480      1490      1500        
pF1KE9 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE
             1510      1520      1530      1540      1550      1560

     1510      1520      1530      1540      1550      1560        
pF1KE9 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR
             1570      1580      1590      1600      1610      1620

     1570      1580  
pF1KE9 DTLNIRQAYNLENV
                     
XP_016 DTLNIRQAYNLENV
             1630    

>>XP_016862244 (OMIM: 606083) PREDICTED: protein polybro  (1655 aa)
 initn: 9543 init1: 9543 opt: 9634  Z-score: 5267.2  bits: 987.5 E(86068):    0
Smith-Waterman score: 10341; 96.8% identity (96.8% similar) in 1614 aa overlap (1-1562:22-1635)

                                    10        20        30         
pF1KE9                      MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS
                            :::::::::::::::::::::::::::::::::::::::
XP_016 MRRLAFRGAGCALVKLKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS
               10        20        30        40        50        60

      40        50        60        70        80        90         
pF1KE9 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ
               70        80        90       100       110       120

     100       110       120       130       140       150         
pF1KE9 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD
              130       140       150       160       170       180

     160       170       180       190       200       210         
pF1KE9 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD
              190       200       210       220       230       240

     220       230       240       250       260       270         
pF1KE9 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI
              250       260       270       280       290       300

     280       290       300       310       320       330         
pF1KE9 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG
              310       320       330       340       350       360

     340       350       360       370       380       390         
pF1KE9 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN
              370       380       390       400       410       420

     400       410       420       430       440       450         
pF1KE9 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA
              430       440       450       460       470       480

     460       470       480       490       500       510         
pF1KE9 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR
              490       500       510       520       530       540

     520       530       540       550       560       570         
pF1KE9 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK
              550       560       570       580       590       600

     580       590       600       610       620       630         
pF1KE9 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL
              610       620       630       640       650       660

     640       650       660       670       680       690         
pF1KE9 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT
              670       680       690       700       710       720

     700       710       720       730       740       750         
pF1KE9 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET
              730       740       750       760       770       780

     760       770       780       790       800       810         
pF1KE9 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP
              790       800       810       820       830       840

     820       830       840       850       860       870         
pF1KE9 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL
              850       860       870       880       890       900

     880       890       900       910       920       930         
pF1KE9 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG
              910       920       930       940       950       960

     940       950       960       970       980       990         
pF1KE9 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY
              970       980       990      1000      1010      1020

    1000      1010      1020      1030      1040      1050         
pF1KE9 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC
             1030      1040      1050      1060      1070      1080

    1060      1070      1080      1090      1100      1110         
pF1KE9 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS
             1090      1100      1110      1120      1130      1140

    1120      1130      1140      1150      1160      1170         
pF1KE9 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI
             1150      1160      1170      1180      1190      1200

    1180      1190      1200      1210      1220      1230         
pF1KE9 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK
             1210      1220      1230      1240      1250      1260

    1240      1250      1260      1270      1280      1290         
pF1KE9 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK
             1270      1280      1290      1300      1310      1320

    1300      1310      1320      1330      1340      1350         
pF1KE9 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT
             1330      1340      1350      1360      1370      1380

    1360      1370      1380      1390      1400      1410         
pF1KE9 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN
             1390      1400      1410      1420      1430      1440

    1420      1430                                                 
pF1KE9 LETAKKAEYEG-------------------------------------------------
       :::::::::::                                                 
XP_016 LETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIP
             1450      1460      1470      1480      1490      1500

                1440      1450      1460      1470      1480       
pF1KE9 ---VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMF
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMF
             1510      1520      1530      1540      1550      1560

      1490      1500      1510      1520      1530      1540       
pF1KE9 VAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK
             1570      1580      1590      1600      1610      1620

      1550      1560      1570      1580  
pF1KE9 SKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
       :::::::::::::::                    
XP_016 SKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
             1630      1640      1650     

>>XP_016862245 (OMIM: 606083) PREDICTED: protein polybro  (1654 aa)
 initn: 7148 init1: 6098 opt: 9616  Z-score: 5257.4  bits: 985.7 E(86068):    0
Smith-Waterman score: 10330; 96.7% identity (96.7% similar) in 1615 aa overlap (1-1563:22-1635)

                                    10        20        30         
pF1KE9                      MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS
                            :::::::::::::::::::::::::::::::::::::::
XP_016 MRRLAFRGAGCALVKLKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLS
               10        20        30        40        50        60

      40        50        60        70        80        90         
pF1KE9 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQ
               70        80        90       100       110       120

     100       110       120       130       140       150         
pF1KE9 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADD
              130       140       150       160       170       180

     160       170       180       190       200       210         
pF1KE9 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD
              190       200       210       220       230       240

     220       230       240       250       260       270         
pF1KE9 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKI
              250       260       270       280       290       300

     280       290       300       310       320       330         
pF1KE9 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQG
              310       320       330       340       350       360

     340       350       360       370       380       390         
pF1KE9 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNN
              370       380       390       400       410       420

     400       410       420       430       440       450         
pF1KE9 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENA
              430       440       450       460       470       480

     460       470       480       490       500       510         
pF1KE9 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIR
              490       500       510       520       530       540

     520       530       540       550       560       570         
pF1KE9 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK
              550       560       570       580       590       600

     580       590       600       610       620       630         
pF1KE9 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL
              610       620       630       640       650       660

     640       650       660       670       680       690         
pF1KE9 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLT
              670       680       690       700       710       720

     700       710       720       730       740       750         
pF1KE9 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET
              730       740       750       760       770       780

     760       770       780       790       800       810         
pF1KE9 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPP
              790       800       810       820       830       840

     820       830       840       850       860       870         
pF1KE9 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDEL
              850       860       870       880       890       900

     880       890       900       910       920       930         
pF1KE9 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAG
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKR-AEKSEDSSGAAG
              910       920       930       940        950         

     940       950       960       970       980       990         
pF1KE9 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFY
     960       970       980       990      1000      1010         

    1000      1010      1020      1030      1040      1050         
pF1KE9 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVC
    1020      1030      1040      1050      1060      1070         

    1060      1070      1080      1090      1100      1110         
pF1KE9 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDS
    1080      1090      1100      1110      1120      1130         

    1120      1130      1140      1150      1160      1170         
pF1KE9 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRI
    1140      1150      1160      1170      1180      1190         

    1180      1190      1200      1210      1220      1230         
pF1KE9 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFK
    1200      1210      1220      1230      1240      1250         

    1240      1250      1260      1270      1280      1290         
pF1KE9 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQK
    1260      1270      1280      1290      1300      1310         

    1300      1310      1320      1330      1340      1350         
pF1KE9 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYT
    1320      1330      1340      1350      1360      1370         

    1360      1370      1380      1390      1400      1410         
pF1KE9 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN
    1380      1390      1400      1410      1420      1430         

    1420      1430                                                 
pF1KE9 LETAKKAEYEG-------------------------------------------------
       :::::::::::                                                 
XP_016 LETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIP
    1440      1450      1460      1470      1480      1490         

                1440      1450      1460      1470      1480       
pF1KE9 ---VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMF
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMF
    1500      1510      1520      1530      1540      1550         

      1490      1500      1510      1520      1530      1540       
pF1KE9 VAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK
    1560      1570      1580      1590      1600      1610         

      1550      1560      1570      1580  
pF1KE9 SKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
       ::::::::::::::::                   
XP_016 SKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
    1620      1630      1640      1650    

>>XP_016862237 (OMIM: 606083) PREDICTED: protein polybro  (1689 aa)
 initn: 10567 init1: 9517 opt: 9538  Z-score: 5214.7  bits: 977.8 E(86068):    0
Smith-Waterman score: 9865; 93.4% identity (93.4% similar) in 1614 aa overlap (1-1507:1-1614)

               10        20        30        40        50        60
pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420                    
pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYE-----------
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE
             1390      1400      1410      1420      1430      1440

                                                                   
pF1KE9 ------------------------------------------------------------
                                                                   
XP_016 RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGP
             1450      1460      1470      1480      1490      1500

                                        1430      1440      1450   
pF1KE9 ------------------------------------GVMNQGVAPMVGTPAPGGSPYGQQ
                                           ::::::::::::::::::::::::
XP_016 VDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQ
             1510      1520      1530      1540      1550      1560

          1460      1470      1480      1490      1500      1510   
pF1KE9 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE
             1570      1580      1590      1600      1610      1620

          1520      1530      1540      1550      1560      1570   
pF1KE9 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI
                                                                   
XP_016 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI
             1630      1640      1650      1660      1670      1680

>--
 initn: 492 init1: 492 opt: 492  Z-score: 282.9  bits: 65.3 E(86068): 5.1e-09
Smith-Waterman score: 492; 100.0% identity (100.0% similar) in 75 aa overlap (1508-1582:1615-1689)

      1480      1490      1500      1510      1520      1530       
pF1KE9 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ
                                     ::::::::::::::::::::::::::::::
XP_016 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ
         1590      1600      1610      1620      1630      1640    

      1540      1550      1560      1570      1580  
pF1KE9 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
         1650      1660      1670      1680         

>>XP_016862238 (OMIM: 606083) PREDICTED: protein polybro  (1689 aa)
 initn: 10567 init1: 9517 opt: 9538  Z-score: 5214.7  bits: 977.8 E(86068):    0
Smith-Waterman score: 9865; 93.4% identity (93.4% similar) in 1614 aa overlap (1-1507:1-1614)

               10        20        30        40        50        60
pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420                    
pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYE-----------
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE
             1390      1400      1410      1420      1430      1440

                                                                   
pF1KE9 ------------------------------------------------------------
                                                                   
XP_016 RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGP
             1450      1460      1470      1480      1490      1500

                                        1430      1440      1450   
pF1KE9 ------------------------------------GVMNQGVAPMVGTPAPGGSPYGQQ
                                           ::::::::::::::::::::::::
XP_016 VDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQ
             1510      1520      1530      1540      1550      1560

          1460      1470      1480      1490      1500      1510   
pF1KE9 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE
             1570      1580      1590      1600      1610      1620

          1520      1530      1540      1550      1560      1570   
pF1KE9 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI
                                                                   
XP_016 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI
             1630      1640      1650      1660      1670      1680

>--
 initn: 492 init1: 492 opt: 492  Z-score: 282.9  bits: 65.3 E(86068): 5.1e-09
Smith-Waterman score: 492; 100.0% identity (100.0% similar) in 75 aa overlap (1508-1582:1615-1689)

      1480      1490      1500      1510      1520      1530       
pF1KE9 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ
                                     ::::::::::::::::::::::::::::::
XP_016 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ
         1590      1600      1610      1620      1630      1640    

      1540      1550      1560      1570      1580  
pF1KE9 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
         1650      1660      1670      1680         

>>XP_016862239 (OMIM: 606083) PREDICTED: protein polybro  (1689 aa)
 initn: 10567 init1: 9517 opt: 9538  Z-score: 5214.7  bits: 977.8 E(86068):    0
Smith-Waterman score: 9865; 93.4% identity (93.4% similar) in 1614 aa overlap (1-1507:1-1614)

               10        20        30        40        50        60
pF1KE9 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE9 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE9 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE9 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE9 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE9 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE9 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE9 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE9 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE9 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE9 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE9 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE9 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE9 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE9 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE9 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE9 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420                    
pF1KE9 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYE-----------
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_016 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE
             1390      1400      1410      1420      1430      1440

                                                                   
pF1KE9 ------------------------------------------------------------
                                                                   
XP_016 RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGP
             1450      1460      1470      1480      1490      1500

                                        1430      1440      1450   
pF1KE9 ------------------------------------GVMNQGVAPMVGTPAPGGSPYGQQ
                                           ::::::::::::::::::::::::
XP_016 VDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQ
             1510      1520      1530      1540      1550      1560

          1460      1470      1480      1490      1500      1510   
pF1KE9 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE
             1570      1580      1590      1600      1610      1620

          1520      1530      1540      1550      1560      1570   
pF1KE9 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI
                                                                   
XP_016 SNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNI
             1630      1640      1650      1660      1670      1680

>--
 initn: 492 init1: 492 opt: 492  Z-score: 282.9  bits: 65.3 E(86068): 5.1e-09
Smith-Waterman score: 492; 100.0% identity (100.0% similar) in 75 aa overlap (1508-1582:1615-1689)

      1480      1490      1500      1510      1520      1530       
pF1KE9 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ
                                     ::::::::::::::::::::::::::::::
XP_016 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ
         1590      1600      1610      1620      1630      1640    

      1540      1550      1560      1570      1580  
pF1KE9 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
         1650      1660      1670      1680         

>>XP_016862233 (OMIM: 606083) PREDICTED: protein polybro  (1707 aa)
 initn: 10567 init1: 9517 opt: 9538  Z-score: 5214.7  bits: 977.8 E(86068):    0
Smith-Waterman score: 9865; 93.4% identity (93.4% similar) in 1614 aa overlap (1-1507:19-1632)

                                 10        20        30        40  
pF1KE9                   MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLP
                         ::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRLAFRGAGCALKKLDSMGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLP
               10        20        30        40        50        60

             50        60        70        80        90       100  
pF1KE9 TVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLK
               70        80        90       100       110       120

            110       120       130       140       150       160  
pF1KE9 MEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDD
              130       140       150       160       170       180

            170       180       190       200       210       220  
pF1KE9 DEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYA
              190       200       210       220       230       240

            230       240       250       260       270       280  
pF1KE9 IIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYM
              250       260       270       280       290       300

            290       300       310       320       330       340  
pF1KE9 KKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRL
              310       320       330       340       350       360

            350       360       370       380       390       400  
pF1KE9 SAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQ
              370       380       390       400       410       420

            410       420       430       440       450       460  
pF1KE9 LIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRY
              430       440       450       460       470       480

            470       480       490       500       510       520  
pF1KE9 NVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQR
              490       500       510       520       530       540

            530       540       550       560       570       580  
pF1KE9 MKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAG
              550       560       570       580       590       600

            590       600       610       620       630       640  
pF1KE9 EEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLS
              610       620       630       640       650       660

            650       660       670       680       690       700  
pF1KE9 RKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKK
              670       680       690       700       710       720

            710       720       730       740       750       760  
pF1KE9 PMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRD
              730       740       750       760       770       780

            770       780       790       800       810       820  
pF1KE9 LEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTF
              790       800       810       820       830       840

            830       840       850       860       870       880  
pF1KE9 DIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKN
              850       860       870       880       890       900

            890       900       910       920       930       940  
pF1KE9 GEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSG
              910       920       930       940       950       960

            950       960       970       980       990      1000  
pF1KE9 LHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPN
              970       980       990      1000      1010      1020

           1010      1020      1030      1040      1050      1060  
pF1KE9 ETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESR
             1030      1040      1050      1060      1070      1080

           1070      1080      1090      1100      1110      1120  
pF1KE9 YSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAE
             1090      1100      1110      1120      1130      1140

           1130      1140      1150      1160      1170      1180  
pF1KE9 DNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKV
             1150      1160      1170      1180      1190      1200

           1190      1200      1210      1220      1230      1240  
pF1KE9 WVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFL
             1210      1220      1230      1240      1250      1260

           1250      1260      1270      1280      1290      1300  
pF1KE9 SCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPS
             1270      1280      1290      1300      1310      1320

           1310      1320      1330      1340      1350      1360  
pF1KE9 PLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQ
             1330      1340      1350      1360      1370      1380

           1370      1380      1390      1400      1410      1420  
pF1KE9 STPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLET
             1390      1400      1410      1420      1430      1440

                                                                   
pF1KE9 AKKAEYE-----------------------------------------------------
       :::::::                                                     
XP_016 AKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTP
             1450      1460      1470      1480      1490      1500

                                                          1430     
pF1KE9 ------------------------------------------------------GVMNQG
                                                             ::::::
XP_016 VAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQG
             1510      1520      1530      1540      1550      1560

        1440      1450      1460      1470      1480      1490     
pF1KE9 VAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQ
             1570      1580      1590      1600      1610      1620

        1500      1510      1520      1530      1540      1550     
pF1KE9 RLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTM
       ::::::::::::                                                
XP_016 RLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTM
             1630      1640      1650      1660      1670      1680

>--
 initn: 492 init1: 492 opt: 492  Z-score: 282.9  bits: 65.3 E(86068): 5.2e-09
Smith-Waterman score: 492; 100.0% identity (100.0% similar) in 75 aa overlap (1508-1582:1633-1707)

      1480      1490      1500      1510      1520      1530       
pF1KE9 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ
                                     ::::::::::::::::::::::::::::::
XP_016 VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQ
           1610      1620      1630      1640      1650      1660  

      1540      1550      1560      1570      1580  
pF1KE9 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV
           1670      1680      1690      1700       




1582 residues in 1 query   sequences
61265892 residues in 86068 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Feb 10 14:59:44 2017 done: Fri Feb 10 14:59:47 2017
 Total Scan time: 19.970 Total Display time:  0.670

Function used was FASTA [36.3.4 Apr, 2011]
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