FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE9279, 290 aa 1>>>pF1KE9279 290 - 290 aa - 290 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9487+/-0.00101; mu= 16.9338+/- 0.061 mean_var=58.9232+/-11.348, 0's: 0 Z-trim(103.9): 20 B-trim: 44 in 1/49 Lambda= 0.167082 statistics sampled from 7624 (7637) to 7624 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.605), E-opt: 0.2 (0.235), width: 16 Scan time: 2.130 The best scores are: opt bits E(32554) CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 ( 290) 2000 490.5 5.9e-139 CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX ( 357) 814 204.7 8e-53 CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 ( 291) 785 197.7 8.6e-51 CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX ( 353) 776 195.5 4.6e-50 CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 ( 279) 597 152.3 3.7e-37 CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 ( 303) 512 131.9 5.8e-31 >>CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 (290 aa) initn: 2000 init1: 2000 opt: 2000 Z-score: 2608.2 bits: 490.5 E(32554): 5.9e-139 Smith-Waterman score: 2000; 100.0% identity (100.0% similar) in 290 aa overlap (1-290:1-290) 10 20 30 40 50 60 pF1KE9 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 KMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYT 190 200 210 220 230 240 250 260 270 280 290 pF1KE9 QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT 250 260 270 280 290 >>CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX (357 aa) initn: 720 init1: 338 opt: 814 Z-score: 1061.8 bits: 204.7 E(32554): 8e-53 Smith-Waterman score: 814; 42.0% identity (75.0% similar) in 276 aa overlap (12-287:84-355) 10 20 30 40 pF1KE9 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFIL : .. .:..:.:. ..:..::: ::..:: CCDS48 EEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLIL 60 70 80 90 100 110 50 60 70 80 90 100 pF1KE9 LFYLVFYGFLTAMFTLTMWVMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTE :.:. ::. :.:..:: :.... :.: . : . .:. ::.:::: ...:. :::. . CCDS48 LIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHSLNFNFNVSEPD 120 130 140 150 160 170 110 120 130 140 150 160 pF1KE9 SWDQHVQKLNKFLEPYNDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCS .:...: .:: ::. ::::.: . : : ::.:. : .: . :.::::.:. : ::: CCDS48 TWQHYVISLNGFLQGYNDSLQEEMNVDCPPGQYFIQ--DGNEDEDKKACQFKRSFLKNCS 180 190 200 210 220 230 170 180 190 200 210 220 pF1KE9 GIGDSTHYGYSTGQPCVFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANG :. : : .::::::::...::::...: .. ..:.: .: : ... .. ..: .. CCDS48 GLEDPT-FGYSTGQPCILLKMNRIVGFRPELGDPVKVSCKVQRG-DENDIRSISYYPESA 240 250 260 270 280 230 240 250 260 270 280 pF1KE9 NIDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRV ..:: :.::::: :::::.::::..: .:. : : :.:.... .. .: :.:.::: CCDS48 SFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRV 290 300 310 320 330 340 290 pF1KE9 AFKLRINKT : : : CCDS48 IFTLNIET 350 >>CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 (291 aa) initn: 704 init1: 314 opt: 785 Z-score: 1025.3 bits: 197.7 E(32554): 8.6e-51 Smith-Waterman score: 785; 39.5% identity (72.6% similar) in 296 aa overlap (1-289:1-291) 10 20 30 40 50 60 pF1KE9 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW :. .:::.::: .::.... ::: : :..::: . :..: :.:..:: .:..:.: .. CCDS95 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY 10 20 30 40 50 60 70 80 90 100 110 pF1KE9 VMLQTVSDHTPKYQDRLATPGLMIRPKT---ENLDVIVNVSDTESWDQHVQKLNKFLEPY :..:::. .:: :::.: .::. .:: . ..:... ::::...: . .: :. :: : CCDS95 VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE9 NDSIQAQKNDV-CRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQP : ::.... : .:. : . . :. : .:.:. .: ::::..: ..:. :.: CCDS95 --SPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADP-NFGFEEGKP 130 140 150 160 170 180 190 200 210 220 230 pF1KE9 CVFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVM---FPANGNIDLMYFPYYGK : .:::::...: . ... : :: :. : ::. .. .: ::...: ::::::: CCDS95 CFIIKMNRIVKFLPSNGSAPRVDCAFL-DQPRE-LGQPLQVKYYPPNGTFSLHYFPYYGK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE9 KFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT : . .:..::::.:.::. :.:: . :.. : ... .. .: . :.: :::.:.: CCDS95 KAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK 240 250 260 270 280 290 >>CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX (353 aa) initn: 742 init1: 297 opt: 776 Z-score: 1012.3 bits: 195.5 E(32554): 4.6e-50 Smith-Waterman score: 776; 41.3% identity (73.9% similar) in 276 aa overlap (12-287:84-351) 10 20 30 40 pF1KE9 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFIL : .. .:..:.:. ..:..::: .:: CCDS14 EEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTG----LIL 60 70 80 90 100 50 60 70 80 90 100 pF1KE9 LFYLVFYGFLTAMFTLTMWVMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTE :.:. ::. :.:..:: :.... :.: . : . .:. ::.:::: ...:. :::. . CCDS14 LIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHSLNFNFNVSEPD 110 120 130 140 150 160 110 120 130 140 150 160 pF1KE9 SWDQHVQKLNKFLEPYNDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCS .:...: .:: ::. ::::.: . : : ::.:. : .: . :.::::.:. : ::: CCDS14 TWQHYVISLNGFLQGYNDSLQEEMNVDCPPGQYFIQ--DGNEDEDKKACQFKRSFLKNCS 170 180 190 200 210 220 170 180 190 200 210 220 pF1KE9 GIGDSTHYGYSTGQPCVFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANG :. : : .::::::::...::::...: .. ..:.: .: : ... .. ..: .. CCDS14 GLEDPT-FGYSTGQPCILLKMNRIVGFRPELGDPVKVSCKVQRG-DENDIRSISYYPESA 230 240 250 260 270 280 230 240 250 260 270 280 pF1KE9 NIDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRV ..:: :.::::: :::::.::::..: .:. : : :.:.... .. .: :.:.::: CCDS14 SFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRV 290 300 310 320 330 340 290 pF1KE9 AFKLRINKT : : : CCDS14 IFTLNIET 350 >>CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 (279 aa) initn: 817 init1: 385 opt: 597 Z-score: 780.7 bits: 152.3 E(32554): 3.7e-37 Smith-Waterman score: 863; 47.6% identity (73.6% similar) in 288 aa overlap (4-285:3-275) 10 20 30 40 50 60 pF1KE9 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW ..:::: .: . ::: :..:: : .:.:::. ::..::::::::::::.:.:..::: CCDS31 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMW 10 20 30 40 50 70 80 90 100 110 pF1KE9 VMLQTVSDHTPKYQDRLATPGLMIRPK-TENLDVIVNVSDTESWDQHVQKLNKFLEPYND :::::..:..:::.:.. .::::. :: . :. . :: :. ... :.:::.:: CCDS31 VMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPY-- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE9 SIQAQKN-DVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCV ... ::: :: : .:: .: . :::: . : :::..: .::: :.::. CCDS31 TLEEQKNLTVCPDGALFEQ--KGPVYV---ACQFPISLLQACSGMNDPD-FGYSQGNPCI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE9 FIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVN ..::::.:.. . .. :..: :.. : ...: :: ::: ::::::::.::. CCDS31 LVKMNRIIGLKPEGVPRID--CVSKN----EDIPNVAVYPHNGMIDLKYFPYYGKKLHVG 180 190 200 210 220 240 250 260 270 280 290 pF1KE9 YTQPLVAVKFLNVTPNV---EVNVECRIN-AANIATDDERDKFAGRVAFKLRINKT : ::::::. .. .:: ::.:::.:. .::. ..:.:::: ::: ::. CCDS31 YLQPLVAVQ-VSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA 230 240 250 260 270 >>CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 (303 aa) initn: 661 init1: 347 opt: 512 Z-score: 669.4 bits: 131.9 E(32554): 5.8e-31 Smith-Waterman score: 729; 39.9% identity (67.0% similar) in 303 aa overlap (11-287:4-301) 10 20 30 40 50 pF1KE9 MVIQKEKKSCGQVVEE--WKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLT :.. :: ::.:.:: . ..:.:::: :: :::::..::: :...: : CCDS12 MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGT 10 20 30 40 50 60 70 80 90 100 110 pF1KE9 MWVMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYN . ::: :.:. : ::::.: ::: :. .. .. .: .:.. .: .. .::: :. CCDS12 IQVMLLTISEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE9 DSIQAQKNDV----CR--PGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYS :: ::..:. : :.. :. : . ...:.:. ::::::..: : :::. CCDS12 DS--AQRDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDET-YGYK 120 130 140 150 160 170 180 190 200 210 pF1KE9 TGQPCVFIKMNRVINFYAGA--NQSMN-------------VTCAGKRDEDAENLGNFVMF :.::..::.:::..: :.:.. : :.:::::: ...:: .: CCDS12 EGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVEYF 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE9 PANGN---IDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDER :: . :.:.::::: .. .: :::.::.: :.: ..:. .::. . ::. . :. CCDS12 GL-GNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYS-EK 240 250 260 270 280 280 290 pF1KE9 DKFAGRVAFKLRINKT :.: :: :... CCDS12 DRFQGRFDVKIEVKS 290 300 290 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:06:20 2016 done: Thu Nov 3 12:06:21 2016 Total Scan time: 2.130 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]