FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE9407, 333 aa 1>>>pF1KE9407 333 - 333 aa - 333 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.1374+/-0.00049; mu= 23.0388+/- 0.031 mean_var=107.1294+/-29.940, 0's: 0 Z-trim(109.4): 562 B-trim: 1706 in 2/47 Lambda= 0.123914 statistics sampled from 16851 (17538) to 16851 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.552), E-opt: 0.2 (0.206), width: 16 Scan time: 7.100 The best scores are: opt bits E(85289) NP_115942 (OMIM: 300903) probable G-protein couple ( 333) 2280 419.1 6.7e-117 NP_001311147 (OMIM: 300529) putative P2Y purinocep ( 339) 1068 202.4 1.1e-51 NP_055314 (OMIM: 300529) putative P2Y purinoceptor ( 339) 1068 202.4 1.1e-51 NP_938147 (OMIM: 300529) putative P2Y purinoceptor ( 339) 1068 202.4 1.1e-51 NP_001311150 (OMIM: 300529) putative P2Y purinocep ( 356) 1068 202.4 1.2e-51 NP_001311154 (OMIM: 300529) putative P2Y purinocep ( 364) 1068 202.4 1.2e-51 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 663 130.1 7.4e-30 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 663 130.1 7.4e-30 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 663 130.1 7.4e-30 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 663 130.1 7.4e-30 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 663 130.1 7.4e-30 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 663 130.1 7.4e-30 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 634 124.8 2.6e-28 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 634 124.8 2.6e-28 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 634 124.8 2.6e-28 NP_001269115 (OMIM: 300201) cysteinyl leukotriene ( 337) 596 118.0 2.9e-26 NP_001269116 (OMIM: 300201) cysteinyl leukotriene ( 337) 596 118.0 2.9e-26 NP_001269117 (OMIM: 300201) cysteinyl leukotriene ( 337) 596 118.0 2.9e-26 NP_006630 (OMIM: 300201) cysteinyl leukotriene rec ( 337) 596 118.0 2.9e-26 NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 556 110.9 4.1e-24 NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 556 110.9 4.1e-24 XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 556 110.9 4.2e-24 NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 556 110.9 4.2e-24 NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 556 110.9 4.2e-24 NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo ( 365) 534 107.0 6.4e-23 NP_002554 (OMIM: 601167) P2Y purinoceptor 1 [Homo ( 373) 533 106.8 7.4e-23 XP_016864712 (OMIM: 600933) PREDICTED: proteinase- ( 383) 526 105.6 1.8e-22 NP_005233 (OMIM: 600933) proteinase-activated rece ( 397) 526 105.6 1.8e-22 NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 525 105.4 2e-22 XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 525 105.4 2e-22 XP_011543376 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 516 103.8 6.1e-22 XP_005274078 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 516 103.8 6.1e-22 XP_005274077 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 516 103.8 6.1e-22 XP_005274076 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 516 103.8 6.1e-22 XP_016873328 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 516 103.8 6.1e-22 NP_788086 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 502 101.3 3.5e-21 NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 502 101.3 3.5e-21 NP_788085 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 502 101.3 3.5e-21 NP_000943 (OMIM: 173393) platelet-activating facto ( 342) 500 100.9 4.2e-21 NP_001158193 (OMIM: 173393) platelet-activating fa ( 342) 500 100.9 4.2e-21 NP_001158194 (OMIM: 173393) platelet-activating fa ( 342) 500 100.9 4.2e-21 NP_001158195 (OMIM: 173393) platelet-activating fa ( 342) 500 100.9 4.2e-21 NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 478 96.9 6.5e-20 NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 478 96.9 6.5e-20 NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 478 96.9 6.5e-20 NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 478 96.9 6.5e-20 NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 478 96.9 6.5e-20 NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 478 96.9 6.5e-20 NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 478 96.9 6.5e-20 NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 478 96.9 6.5e-20 >>NP_115942 (OMIM: 300903) probable G-protein coupled re (333 aa) initn: 2280 init1: 2280 opt: 2280 Z-score: 2219.7 bits: 419.1 E(85289): 6.7e-117 Smith-Waterman score: 2280; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMIN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 LAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 LAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 MYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 MYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 QSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 QSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 ICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 ICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFR 250 260 270 280 290 300 310 320 330 pF1KE9 RRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC ::::::::::::::::::::::::::::::::: NP_115 RRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC 310 320 330 >>NP_001311147 (OMIM: 300529) putative P2Y purinoceptor (339 aa) initn: 1031 init1: 574 opt: 1068 Z-score: 1048.6 bits: 202.4 E(85289): 1.1e-51 Smith-Waterman score: 1068; 49.7% identity (79.1% similar) in 316 aa overlap (14-328:29-337) 10 20 30 40 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFY :. :.: .::.:: .:..:::..: ::::. NP_001 MANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE9 GYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYAS .... ..:.::::::..::: .::::::::.::..: ::: .::..::::::.::::: NP_001 RFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYAS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE9 IYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNR : ::.:::..: .::. ::: .: :..::. :: : :... ::. ::.:: : : ..:. NP_001 ICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILR-STDLNNNK 130 140 150 160 170 170 180 190 200 210 220 pF1KE9 TKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMA-QDLGE . ::.:: ...: . : :.:..:: ::: :..:. .:::::..::. . ::: : ..: NP_001 S-CFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLR-QPPMAFQGISE 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE9 KQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLN .::::.:.. ::.::.:::.:::..: . .:: . :.:: . :. : :: :::::: NP_001 RQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLASLC 240 250 260 270 280 290 290 300 310 320 330 pF1KE9 SCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC :::..::: ..::: .::: : : ... ..:....:.: NP_001 CLLDPILYYFMASEFRDQLSR---HGSSVTRSR-LMSKESGSSMIG 300 310 320 330 >>NP_055314 (OMIM: 300529) putative P2Y purinoceptor 10 (339 aa) initn: 1031 init1: 574 opt: 1068 Z-score: 1048.6 bits: 202.4 E(85289): 1.1e-51 Smith-Waterman score: 1068; 49.7% identity (79.1% similar) in 316 aa overlap (14-328:29-337) 10 20 30 40 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFY :. :.: .::.:: .:..:::..: ::::. NP_055 MANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE9 GYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYAS .... ..:.::::::..::: .::::::::.::..: ::: .::..::::::.::::: NP_055 RFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYAS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE9 IYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNR : ::.:::..: .::. ::: .: :..::. :: : :... ::. ::.:: : : ..:. NP_055 ICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILR-STDLNNNK 130 140 150 160 170 170 180 190 200 210 220 pF1KE9 TKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMA-QDLGE . ::.:: ...: . : :.:..:: ::: :..:. .:::::..::. . ::: : ..: NP_055 S-CFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLR-QPPMAFQGISE 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE9 KQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLN .::::.:.. ::.::.:::.:::..: . .:: . :.:: . :. : :: :::::: NP_055 RQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLASLC 240 250 260 270 280 290 290 300 310 320 330 pF1KE9 SCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC :::..::: ..::: .::: : : ... ..:....:.: NP_055 CLLDPILYYFMASEFRDQLSR---HGSSVTRSR-LMSKESGSSMIG 300 310 320 330 >>NP_938147 (OMIM: 300529) putative P2Y purinoceptor 10 (339 aa) initn: 1031 init1: 574 opt: 1068 Z-score: 1048.6 bits: 202.4 E(85289): 1.1e-51 Smith-Waterman score: 1068; 49.7% identity (79.1% similar) in 316 aa overlap (14-328:29-337) 10 20 30 40 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFY :. :.: .::.:: .:..:::..: ::::. NP_938 MANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE9 GYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYAS .... ..:.::::::..::: .::::::::.::..: ::: .::..::::::.::::: NP_938 RFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYAS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE9 IYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNR : ::.:::..: .::. ::: .: :..::. :: : :... ::. ::.:: : : ..:. NP_938 ICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILR-STDLNNNK 130 140 150 160 170 170 180 190 200 210 220 pF1KE9 TKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMA-QDLGE . ::.:: ...: . : :.:..:: ::: :..:. .:::::..::. . ::: : ..: NP_938 S-CFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLR-QPPMAFQGISE 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE9 KQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLN .::::.:.. ::.::.:::.:::..: . .:: . :.:: . :. : :: :::::: NP_938 RQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLASLC 240 250 260 270 280 290 290 300 310 320 330 pF1KE9 SCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC :::..::: ..::: .::: : : ... ..:....:.: NP_938 CLLDPILYYFMASEFRDQLSR---HGSSVTRSR-LMSKESGSSMIG 300 310 320 330 >>NP_001311150 (OMIM: 300529) putative P2Y purinoceptor (356 aa) initn: 1031 init1: 574 opt: 1068 Z-score: 1048.4 bits: 202.4 E(85289): 1.2e-51 Smith-Waterman score: 1068; 49.7% identity (79.1% similar) in 316 aa overlap (14-328:46-354) 10 20 30 40 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWV :. :.: .::.:: .:..:::..: :::: NP_001 KSMANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWV 20 30 40 50 60 70 50 60 70 80 90 100 pF1KE9 FYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMY . .... ..:.::::::..::: .::::::::.::..: ::: .::..::::::.::: NP_001 LCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMY 80 90 100 110 120 130 110 120 130 140 150 160 pF1KE9 ASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSG ::: ::.:::..: .::. ::: .: :..::. :: : :... ::. ::.:: : : .. NP_001 ASICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILR-STDLNN 140 150 160 170 180 190 170 180 190 200 210 220 pF1KE9 NRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMA-QDL :.. ::.:: ...: . : :.:..:: ::: :..:. .:::::..::. . ::: : . NP_001 NKS-CFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLR-QPPMAFQGI 200 210 220 230 240 250 230 240 250 260 270 280 pF1KE9 GEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLAS .:.::::.:.. ::.::.:::.:::..: . .:: . :.:: . :. : :: ::::: NP_001 SERQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLAS 260 270 280 290 300 310 290 300 310 320 330 pF1KE9 LNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC : :::..::: ..::: .::: : : ... ..:....:.: NP_001 LCCLLDPILYYFMASEFRDQLSR---HGSSVTRSR-LMSKESGSSMIG 320 330 340 350 >>NP_001311154 (OMIM: 300529) putative P2Y purinoceptor (364 aa) initn: 1031 init1: 574 opt: 1068 Z-score: 1048.4 bits: 202.4 E(85289): 1.2e-51 Smith-Waterman score: 1068; 49.7% identity (79.1% similar) in 316 aa overlap (14-328:54-362) 10 20 30 40 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWV :. :.: .::.:: .:..:::..: :::: NP_001 KSMANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWV 30 40 50 60 70 80 50 60 70 80 90 100 pF1KE9 FYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMY . .... ..:.::::::..::: .::::::::.::..: ::: .::..::::::.::: NP_001 LCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMY 90 100 110 120 130 140 110 120 130 140 150 160 pF1KE9 ASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSG ::: ::.:::..: .::. ::: .: :..::. :: : :... ::. ::.:: : : .. NP_001 ASICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILR-STDLNN 150 160 170 180 190 200 170 180 190 200 210 220 pF1KE9 NRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMA-QDL :.. ::.:: ...: . : :.:..:: ::: :..:. .:::::..::. . ::: : . NP_001 NKS-CFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLR-QPPMAFQGI 210 220 230 240 250 260 230 240 250 260 270 280 pF1KE9 GEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLAS .:.::::.:.. ::.::.:::.:::..: . .:: . :.:: . :. : :: ::::: NP_001 SERQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLAS 270 280 290 300 310 320 290 300 310 320 330 pF1KE9 LNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC : :::..::: ..::: .::: : : ... ..:....:.: NP_001 LCCLLDPILYYFMASEFRDQLSR---HGSSVTRSR-LMSKESGSSMIG 330 340 350 360 >>XP_016884927 (OMIM: 300086) PREDICTED: lysophosphatidi (370 aa) initn: 653 init1: 362 opt: 663 Z-score: 657.0 bits: 130.1 E(85289): 7.4e-30 Smith-Waterman score: 663; 34.2% identity (64.5% similar) in 330 aa overlap (3-332:27-346) 10 20 30 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIG :: :: :. :.: . ...:.:... ::: XP_016 MGDRRFIDFQFQDSNSSLRPRLGNATANNTCIVDDS----FKYNLNGAVYSVVFILGLIT 10 20 30 40 50 40 50 60 70 80 90 pF1KE9 NILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFY : ..:.:: :: ....::. :::..::: : .::..::: .:. :::: :: . XP_016 NSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGT 60 70 80 90 100 110 100 110 120 130 140 150 pF1KE9 LKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLR .:.:.:. ::.:::: :: ..:::: . . . . : :: :. :. . : XP_016 AFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLF 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE9 TSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKY .. .... : :: . : . : . . : :..::. ::.. . :. .. .:. XP_016 STTNVNNATTTCFEGFSKRVWKTYLSKITIFI-EVVGFIIPLILNVSCSSVVLRTLRKPA 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE9 PMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSV ..: .:.:.:::: . .::..::.::. . : ::.:. : .:. .: :.. . XP_016 TLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCFLERFAKIMYPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE9 ALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC .::::.:: :.:: ::::. . :.. ... . ... .:. ...: : : : XP_016 TLCLATLNCCFDPFIYYFTLESFQK-----SFYINAHIRMESLFKTETPLTTKPSLPAIQ 300 310 320 330 340 350 XP_016 EEVSDQTTNNGGELMLESTF 360 370 >>NP_001264929 (OMIM: 300086) lysophosphatidic acid rece (370 aa) initn: 653 init1: 362 opt: 663 Z-score: 657.0 bits: 130.1 E(85289): 7.4e-30 Smith-Waterman score: 663; 34.2% identity (64.5% similar) in 330 aa overlap (3-332:27-346) 10 20 30 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIG :: :: :. :.: . ...:.:... ::: NP_001 MGDRRFIDFQFQDSNSSLRPRLGNATANNTCIVDDS----FKYNLNGAVYSVVFILGLIT 10 20 30 40 50 40 50 60 70 80 90 pF1KE9 NILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFY : ..:.:: :: ....::. :::..::: : .::..::: .:. :::: :: . NP_001 NSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGT 60 70 80 90 100 110 100 110 120 130 140 150 pF1KE9 LKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLR .:.:.:. ::.:::: :: ..:::: . . . . : :: :. :. . : NP_001 AFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLF 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE9 TSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKY .. .... : :: . : . : . . : :..::. ::.. . :. .. .:. NP_001 STTNVNNATTTCFEGFSKRVWKTYLSKITIFI-EVVGFIIPLILNVSCSSVVLRTLRKPA 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE9 PMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSV ..: .:.:.:::: . .::..::.::. . : ::.:. : .:. .: :.. . NP_001 TLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCFLERFAKIMYPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE9 ALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC .::::.:: :.:: ::::. . :.. ... . ... .:. ...: : : : NP_001 TLCLATLNCCFDPFIYYFTLESFQK-----SFYINAHIRMESLFKTETPLTTKPSLPAIQ 300 310 320 330 340 350 NP_001 EEVSDQTTNNGGELMLESTF 360 370 >>NP_005287 (OMIM: 300086) lysophosphatidic acid recepto (370 aa) initn: 653 init1: 362 opt: 663 Z-score: 657.0 bits: 130.1 E(85289): 7.4e-30 Smith-Waterman score: 663; 34.2% identity (64.5% similar) in 330 aa overlap (3-332:27-346) 10 20 30 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIG :: :: :. :.: . ...:.:... ::: NP_005 MGDRRFIDFQFQDSNSSLRPRLGNATANNTCIVDDS----FKYNLNGAVYSVVFILGLIT 10 20 30 40 50 40 50 60 70 80 90 pF1KE9 NILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFY : ..:.:: :: ....::. :::..::: : .::..::: .:. :::: :: . NP_005 NSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGT 60 70 80 90 100 110 100 110 120 130 140 150 pF1KE9 LKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLR .:.:.:. ::.:::: :: ..:::: . . . . : :: :. :. . : NP_005 AFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLF 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE9 TSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKY .. .... : :: . : . : . . : :..::. ::.. . :. .. .:. NP_005 STTNVNNATTTCFEGFSKRVWKTYLSKITIFI-EVVGFIIPLILNVSCSSVVLRTLRKPA 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE9 PMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSV ..: .:.:.:::: . .::..::.::. . : ::.:. : .:. .: :.. . NP_005 TLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCFLERFAKIMYPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE9 ALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC .::::.:: :.:: ::::. . :.. ... . ... .:. ...: : : : NP_005 TLCLATLNCCFDPFIYYFTLESFQK-----SFYINAHIRMESLFKTETPLTTKPSLPAIQ 300 310 320 330 340 350 NP_005 EEVSDQTTNNGGELMLESTF 360 370 >>XP_005262183 (OMIM: 300086) PREDICTED: lysophosphatidi (370 aa) initn: 653 init1: 362 opt: 663 Z-score: 657.0 bits: 130.1 E(85289): 7.4e-30 Smith-Waterman score: 663; 34.2% identity (64.5% similar) in 330 aa overlap (3-332:27-346) 10 20 30 pF1KE9 MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIG :: :: :. :.: . ...:.:... ::: XP_005 MGDRRFIDFQFQDSNSSLRPRLGNATANNTCIVDDS----FKYNLNGAVYSVVFILGLIT 10 20 30 40 50 40 50 60 70 80 90 pF1KE9 NILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFY : ..:.:: :: ....::. :::..::: : .::..::: .:. :::: :: . XP_005 NSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGT 60 70 80 90 100 110 100 110 120 130 140 150 pF1KE9 LKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLR .:.:.:. ::.:::: :: ..:::: . . . . : :: :. :. . : XP_005 AFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLF 120 130 140 150 160 170 160 170 180 190 200 210 pF1KE9 TSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKY .. .... : :: . : . : . . : :..::. ::.. . :. .. .:. XP_005 STTNVNNATTTCFEGFSKRVWKTYLSKITIFI-EVVGFIIPLILNVSCSSVVLRTLRKPA 180 190 200 210 220 230 220 230 240 250 260 270 pF1KE9 PMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSV ..: .:.:.:::: . .::..::.::. . : ::.:. : .:. .: :.. . XP_005 TLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCFLERFAKIMYPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE9 ALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC .::::.:: :.:: ::::. . :.. ... . ... .:. ...: : : : XP_005 TLCLATLNCCFDPFIYYFTLESFQK-----SFYINAHIRMESLFKTETPLTTKPSLPAIQ 300 310 320 330 340 350 XP_005 EEVSDQTTNNGGELMLESTF 360 370 333 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 12:46:33 2016 done: Sun Nov 6 12:46:35 2016 Total Scan time: 7.100 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]