FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE9419, 469 aa 1>>>pF1KE9419 469 - 469 aa - 469 aa Library: /omim/omim.rfq.tfa 63214209 residues in 88908 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7185+/-0.000294; mu= 22.7024+/- 0.019 mean_var=101.6259+/-23.714, 0's: 0 Z-trim(118.8): 487 B-trim: 1661 in 1/58 Lambda= 0.127225 statistics sampled from 32114 (32744) to 32114 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.368), width: 16 Scan time: 9.910 The best scores are: opt bits E(88908) NP_057652 (OMIM: 609445) relaxin-3 receptor 1 [Hom ( 469) 3159 590.4 3.8e-168 NP_871001 (OMIM: 609043) relaxin-3 receptor 2 [Hom ( 374) 364 77.2 8.9e-14 XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 332 71.4 5.6e-12 NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 332 71.4 5.6e-12 XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 332 71.4 5.6e-12 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 332 71.4 5.6e-12 XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 332 71.4 5.6e-12 XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 332 71.4 5.6e-12 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 332 71.4 5.6e-12 NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 325 70.0 1.3e-11 NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 325 70.0 1.3e-11 NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 321 69.3 2.1e-11 NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 321 69.3 2.1e-11 NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 321 69.3 2.2e-11 NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 321 69.3 2.2e-11 NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 321 69.3 2.2e-11 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 314 68.0 5.1e-11 NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 306 66.6 1.4e-10 NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 305 66.3 1.5e-10 NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 298 65.1 4e-10 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 294 64.4 6.8e-10 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 292 64.0 8.7e-10 XP_016859321 (OMIM: 600239) PREDICTED: G-protein c ( 355) 291 63.8 9.4e-10 NP_001091669 (OMIM: 600239) G-protein coupled rece ( 355) 291 63.8 9.4e-10 NP_001248381 (OMIM: 600239) G-protein coupled rece ( 355) 291 63.8 9.4e-10 NP_001248382 (OMIM: 600239) G-protein coupled rece ( 355) 291 63.8 9.4e-10 NP_001248384 (OMIM: 600239) G-protein coupled rece ( 355) 291 63.8 9.4e-10 NP_005270 (OMIM: 600239) G-protein coupled recepto ( 355) 291 63.8 9.4e-10 NP_001248383 (OMIM: 600239) G-protein coupled rece ( 355) 291 63.8 9.4e-10 XP_005246528 (OMIM: 600239) PREDICTED: G-protein c ( 355) 291 63.8 9.4e-10 XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 288 63.3 1.4e-09 XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 288 63.3 1.4e-09 XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 288 63.3 1.4e-09 NP_005289 (OMIM: 602174) probable G-protein couple ( 361) 284 62.5 2.3e-09 NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 284 62.5 2.3e-09 NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 284 62.5 2.3e-09 XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 284 62.5 2.3e-09 NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 284 62.5 2.3e-09 NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 284 62.6 2.4e-09 NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 283 62.3 2.7e-09 NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 283 62.4 2.7e-09 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 283 62.4 2.8e-09 NP_000677 (OMIM: 300034) type-2 angiotensin II rec ( 363) 282 62.1 3e-09 XP_011535835 (OMIM: 300034) PREDICTED: type-2 angi ( 363) 282 62.1 3e-09 NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 280 61.7 3.6e-09 XP_016874309 (OMIM: 602351) PREDICTED: chemokine-l ( 371) 279 61.6 4.4e-09 NP_004063 (OMIM: 602351) chemokine-like receptor 1 ( 371) 279 61.6 4.4e-09 NP_001135817 (OMIM: 602351) chemokine-like recepto ( 373) 279 61.6 4.4e-09 NP_001135815 (OMIM: 602351) chemokine-like recepto ( 373) 279 61.6 4.4e-09 NP_001135816 (OMIM: 602351) chemokine-like recepto ( 373) 279 61.6 4.4e-09 >>NP_057652 (OMIM: 609445) relaxin-3 receptor 1 [Homo sa (469 aa) initn: 3159 init1: 3159 opt: 3159 Z-score: 3140.1 bits: 590.4 E(88908): 3.8e-168 Smith-Waterman score: 3159; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469) 10 20 30 40 50 60 pF1KE9 MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 PPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 VTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 YHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 VMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTA 370 380 390 400 410 420 430 440 450 460 pF1KE9 TTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY ::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 TTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY 430 440 450 460 >>NP_871001 (OMIM: 609043) relaxin-3 receptor 2 [Homo sa (374 aa) initn: 793 init1: 364 opt: 364 Z-score: 368.6 bits: 77.2 E(88908): 8.9e-14 Smith-Waterman score: 857; 41.8% identity (67.0% similar) in 361 aa overlap (56-400:1-320) 30 40 50 60 70 pF1KE9 SLVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPP------GSGG----AESAD .: . :: .::: :..: NP_871 MPTLNTSASPPTFFWANASGGSVLSADDAP 10 20 30 80 90 100 110 120 pF1KE9 TEAR---VRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSS---INLFVTNLALTDF .. .:......: .: :.:: ::: ::..... :.. . :: ::::.:. NP_871 MPVKFLALRLMVALAYGLVGAIGLLGNLAVLWVLSNCA--RRAPGPPSDTFVFNLALADL 40 50 60 70 80 130 140 150 160 170 180 pF1KE9 QFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALK ..:::::::.:.::::.:::: :.::.: .: .:.:::.:..::.::.:: :: : NP_871 GLALTLPFWAAESALDFHWPFGGALCKMVLTATVLNVYASIFLITALSVARYWVVAMAA- 90 100 110 120 130 140 190 200 210 220 230 240 pF1KE9 SHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLV : : :: : :. . .:: :::...:.:.:.. .: : .:::. NP_871 -----GPGTH----LSL-----FWARIATLAVWAAAALVTVPTAVFGVEGEVCGVRLCLL 150 160 170 180 190 250 260 270 280 290 300 pF1KE9 RFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVA :::.. .::: :. :.:.:.:..:::.: ::::. :. .:: . . .:: NP_871 RFPSR-------YWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFL-QRRQRRRQDSRVVA 200 210 220 230 240 310 320 330 340 350 360 pF1KE9 GGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVY .:: :.: ::::::.::...: :..:.::. ::... .. :.: NP_871 ----------------RSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTY 250 260 270 280 370 380 390 400 410 420 pF1KE9 AFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATTKPEHEDQ .:::..::::::::::::::::.::: :.:: NP_871 VFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQGGGWVQQVALKQVGR 290 300 310 320 330 340 430 440 450 460 pF1KE9 GLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY NP_871 RWVASNPRESRPSTLLTNLDRGTPG 350 360 370 >>XP_005261778 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 502 init1: 156 opt: 332 Z-score: 336.4 bits: 71.4 E(88908): 5.6e-12 Smith-Waterman score: 564; 32.5% identity (58.0% similar) in 381 aa overlap (57-429:15-353) 30 40 50 60 70 80 pF1KE9 LVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGS--GGAESADTEARVRI-- :..: . :: . :.. .. . : . . XP_005 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSG 10 20 30 40 90 100 110 120 130 140 pF1KE9 -LISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE :: .:: :::..:: :: ::.:.. . : :... ::::.: :.: ::: :.. XP_005 VLIPLVYLVVCVVGLLGNSLVIYVVLRHTA-SPSVTNVYILNLALADELFMLGLPFLAAQ 50 60 70 80 90 100 150 160 170 180 190 200 pF1KE9 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC :::.. ::::. ::..: : ..:...:.: ::.::: :: .:. .: : : XP_005 NALSY-WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAP---- 110 120 130 140 150 210 220 230 240 250 260 pF1KE9 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ :... . .:. .:.. :: ..:: . . : : ...:. . XP_005 -----------VARTVSAAVWVASAVVVLPVVVFSGVPR--GMSTCHMQWPEPAAA---- 160 170 180 190 200 270 280 290 300 310 320 pF1KE9 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL : . . . ::: :: .: :::::.: . :.:: . : :. :: XP_005 -WRAGFIIYTAALGFFGPLLVICLCYLLIVVKV---RSAGRRVWA------PSCQRRRRS 210 220 230 240 250 330 340 350 360 370 pF1KE9 SK-VTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVP-FSQEYFLCQVYAFPVSVCLAH . ::. :. :: : :::.: .:. ... . : : ::: : :.: . XP_005 ERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFL--VVALP------Y 260 270 280 290 300 380 390 400 410 420 430 pF1KE9 SNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATT-KPEHEDQGLQAPAPPH .::: ::.:: .. .:..... .: : : . :..: .. : :.::. XP_005 ANSCANPILYGFLSYRFKQGFRRVLLR-PSRRVRSQEPTVGPPEKTEEEDEEEEDGEESR 310 320 330 340 350 360 440 450 460 pF1KE9 AAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY XP_005 EGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>NP_001042 (OMIM: 182453) somatostatin receptor type 3 (418 aa) initn: 502 init1: 156 opt: 332 Z-score: 336.4 bits: 71.4 E(88908): 5.6e-12 Smith-Waterman score: 564; 32.5% identity (58.0% similar) in 381 aa overlap (57-429:15-353) 30 40 50 60 70 80 pF1KE9 LVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGS--GGAESADTEARVRI-- :..: . :: . :.. .. . : . . NP_001 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSG 10 20 30 40 90 100 110 120 130 140 pF1KE9 -LISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE :: .:: :::..:: :: ::.:.. . : :... ::::.: :.: ::: :.. NP_001 VLIPLVYLVVCVVGLLGNSLVIYVVLRHTA-SPSVTNVYILNLALADELFMLGLPFLAAQ 50 60 70 80 90 100 150 160 170 180 190 200 pF1KE9 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC :::.. ::::. ::..: : ..:...:.: ::.::: :: .:. .: : : NP_001 NALSY-WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAP---- 110 120 130 140 150 210 220 230 240 250 260 pF1KE9 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ :... . .:. .:.. :: ..:: . . : : ...:. . NP_001 -----------VARTVSAAVWVASAVVVLPVVVFSGVPR--GMSTCHMQWPEPAAA---- 160 170 180 190 200 270 280 290 300 310 320 pF1KE9 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL : . . . ::: :: .: :::::.: . :.:: . : :. :: NP_001 -WRAGFIIYTAALGFFGPLLVICLCYLLIVVKV---RSAGRRVWA------PSCQRRRRS 210 220 230 240 250 330 340 350 360 370 pF1KE9 SK-VTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVP-FSQEYFLCQVYAFPVSVCLAH . ::. :. :: : :::.: .:. ... . : : ::: : :.: . NP_001 ERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFL--VVALP------Y 260 270 280 290 300 380 390 400 410 420 430 pF1KE9 SNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATT-KPEHEDQGLQAPAPPH .::: ::.:: .. .:..... .: : : . :..: .. : :.::. NP_001 ANSCANPILYGFLSYRFKQGFRRVLLR-PSRRVRSQEPTVGPPEKTEEEDEEEEDGEESR 310 320 330 340 350 360 440 450 460 pF1KE9 AAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY NP_001 EGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_011528651 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 502 init1: 156 opt: 332 Z-score: 336.4 bits: 71.4 E(88908): 5.6e-12 Smith-Waterman score: 564; 32.5% identity (58.0% similar) in 381 aa overlap (57-429:15-353) 30 40 50 60 70 80 pF1KE9 LVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGS--GGAESADTEARVRI-- :..: . :: . :.. .. . : . . XP_011 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSG 10 20 30 40 90 100 110 120 130 140 pF1KE9 -LISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE :: .:: :::..:: :: ::.:.. . : :... ::::.: :.: ::: :.. XP_011 VLIPLVYLVVCVVGLLGNSLVIYVVLRHTA-SPSVTNVYILNLALADELFMLGLPFLAAQ 50 60 70 80 90 100 150 160 170 180 190 200 pF1KE9 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC :::.. ::::. ::..: : ..:...:.: ::.::: :: .:. .: : : XP_011 NALSY-WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAP---- 110 120 130 140 150 210 220 230 240 250 260 pF1KE9 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ :... . .:. .:.. :: ..:: . . : : ...:. . XP_011 -----------VARTVSAAVWVASAVVVLPVVVFSGVPR--GMSTCHMQWPEPAAA---- 160 170 180 190 200 270 280 290 300 310 320 pF1KE9 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL : . . . ::: :: .: :::::.: . :.:: . : :. :: XP_011 -WRAGFIIYTAALGFFGPLLVICLCYLLIVVKV---RSAGRRVWA------PSCQRRRRS 210 220 230 240 250 330 340 350 360 370 pF1KE9 SK-VTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVP-FSQEYFLCQVYAFPVSVCLAH . ::. :. :: : :::.: .:. ... . : : ::: : :.: . XP_011 ERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFL--VVALP------Y 260 270 280 290 300 380 390 400 410 420 430 pF1KE9 SNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATT-KPEHEDQGLQAPAPPH .::: ::.:: .. .:..... .: : : . :..: .. : :.::. XP_011 ANSCANPILYGFLSYRFKQGFRRVLLR-PSRRVRSQEPTVGPPEKTEEEDEEEEDGEESR 310 320 330 340 350 360 440 450 460 pF1KE9 AAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY XP_011 EGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_006724374 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 502 init1: 156 opt: 332 Z-score: 336.4 bits: 71.4 E(88908): 5.6e-12 Smith-Waterman score: 564; 32.5% identity (58.0% similar) in 381 aa overlap (57-429:15-353) 30 40 50 60 70 80 pF1KE9 LVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGS--GGAESADTEARVRI-- :..: . :: . :.. .. . : . . XP_006 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSG 10 20 30 40 90 100 110 120 130 140 pF1KE9 -LISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE :: .:: :::..:: :: ::.:.. . : :... ::::.: :.: ::: :.. XP_006 VLIPLVYLVVCVVGLLGNSLVIYVVLRHTA-SPSVTNVYILNLALADELFMLGLPFLAAQ 50 60 70 80 90 100 150 160 170 180 190 200 pF1KE9 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC :::.. ::::. ::..: : ..:...:.: ::.::: :: .:. .: : : XP_006 NALSY-WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAP---- 110 120 130 140 150 210 220 230 240 250 260 pF1KE9 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ :... . .:. .:.. :: ..:: . . : : ...:. . XP_006 -----------VARTVSAAVWVASAVVVLPVVVFSGVPR--GMSTCHMQWPEPAAA---- 160 170 180 190 200 270 280 290 300 310 320 pF1KE9 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL : . . . ::: :: .: :::::.: . :.:: . : :. :: XP_006 -WRAGFIIYTAALGFFGPLLVICLCYLLIVVKV---RSAGRRVWA------PSCQRRRRS 210 220 230 240 250 330 340 350 360 370 pF1KE9 SK-VTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVP-FSQEYFLCQVYAFPVSVCLAH . ::. :. :: : :::.: .:. ... . : : ::: : :.: . XP_006 ERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFL--VVALP------Y 260 270 280 290 300 380 390 400 410 420 430 pF1KE9 SNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATT-KPEHEDQGLQAPAPPH .::: ::.:: .. .:..... .: : : . :..: .. : :.::. XP_006 ANSCANPILYGFLSYRFKQGFRRVLLR-PSRRVRSQEPTVGPPEKTEEEDEEEEDGEESR 310 320 330 340 350 360 440 450 460 pF1KE9 AAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY XP_006 EGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_016884413 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 502 init1: 156 opt: 332 Z-score: 336.4 bits: 71.4 E(88908): 5.6e-12 Smith-Waterman score: 564; 32.5% identity (58.0% similar) in 381 aa overlap (57-429:15-353) 30 40 50 60 70 80 pF1KE9 LVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGS--GGAESADTEARVRI-- :..: . :: . :.. .. . : . . XP_016 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSG 10 20 30 40 90 100 110 120 130 140 pF1KE9 -LISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE :: .:: :::..:: :: ::.:.. . : :... ::::.: :.: ::: :.. XP_016 VLIPLVYLVVCVVGLLGNSLVIYVVLRHTA-SPSVTNVYILNLALADELFMLGLPFLAAQ 50 60 70 80 90 100 150 160 170 180 190 200 pF1KE9 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC :::.. ::::. ::..: : ..:...:.: ::.::: :: .:. .: : : XP_016 NALSY-WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAP---- 110 120 130 140 150 210 220 230 240 250 260 pF1KE9 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ :... . .:. .:.. :: ..:: . . : : ...:. . XP_016 -----------VARTVSAAVWVASAVVVLPVVVFSGVPR--GMSTCHMQWPEPAAA---- 160 170 180 190 200 270 280 290 300 310 320 pF1KE9 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL : . . . ::: :: .: :::::.: . :.:: . : :. :: XP_016 -WRAGFIIYTAALGFFGPLLVICLCYLLIVVKV---RSAGRRVWA------PSCQRRRRS 210 220 230 240 250 330 340 350 360 370 pF1KE9 SK-VTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVP-FSQEYFLCQVYAFPVSVCLAH . ::. :. :: : :::.: .:. ... . : : ::: : :.: . XP_016 ERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFL--VVALP------Y 260 270 280 290 300 380 390 400 410 420 430 pF1KE9 SNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATT-KPEHEDQGLQAPAPPH .::: ::.:: .. .:..... .: : : . :..: .. : :.::. XP_016 ANSCANPILYGFLSYRFKQGFRRVLLR-PSRRVRSQEPTVGPPEKTEEEDEEEEDGEESR 310 320 330 340 350 360 440 450 460 pF1KE9 AAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY XP_016 EGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_016884412 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 502 init1: 156 opt: 332 Z-score: 336.4 bits: 71.4 E(88908): 5.6e-12 Smith-Waterman score: 564; 32.5% identity (58.0% similar) in 381 aa overlap (57-429:15-353) 30 40 50 60 70 80 pF1KE9 LVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGS--GGAESADTEARVRI-- :..: . :: . :.. .. . : . . XP_016 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSG 10 20 30 40 90 100 110 120 130 140 pF1KE9 -LISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE :: .:: :::..:: :: ::.:.. . : :... ::::.: :.: ::: :.. XP_016 VLIPLVYLVVCVVGLLGNSLVIYVVLRHTA-SPSVTNVYILNLALADELFMLGLPFLAAQ 50 60 70 80 90 100 150 160 170 180 190 200 pF1KE9 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC :::.. ::::. ::..: : ..:...:.: ::.::: :: .:. .: : : XP_016 NALSY-WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAP---- 110 120 130 140 150 210 220 230 240 250 260 pF1KE9 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ :... . .:. .:.. :: ..:: . . : : ...:. . XP_016 -----------VARTVSAAVWVASAVVVLPVVVFSGVPR--GMSTCHMQWPEPAAA---- 160 170 180 190 200 270 280 290 300 310 320 pF1KE9 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL : . . . ::: :: .: :::::.: . :.:: . : :. :: XP_016 -WRAGFIIYTAALGFFGPLLVICLCYLLIVVKV---RSAGRRVWA------PSCQRRRRS 210 220 230 240 250 330 340 350 360 370 pF1KE9 SK-VTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVP-FSQEYFLCQVYAFPVSVCLAH . ::. :. :: : :::.: .:. ... . : : ::: : :.: . XP_016 ERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFL--VVALP------Y 260 270 280 290 300 380 390 400 410 420 430 pF1KE9 SNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATT-KPEHEDQGLQAPAPPH .::: ::.:: .. .:..... .: : : . :..: .. : :.::. XP_016 ANSCANPILYGFLSYRFKQGFRRVLLR-PSRRVRSQEPTVGPPEKTEEEDEEEEDGEESR 310 320 330 340 350 360 440 450 460 pF1KE9 AAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY XP_016 EGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>NP_001265616 (OMIM: 182453) somatostatin receptor type (418 aa) initn: 502 init1: 156 opt: 332 Z-score: 336.4 bits: 71.4 E(88908): 5.6e-12 Smith-Waterman score: 564; 32.5% identity (58.0% similar) in 381 aa overlap (57-429:15-353) 30 40 50 60 70 80 pF1KE9 LVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGS--GGAESADTEARVRI-- :..: . :: . :.. .. . : . . NP_001 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSG 10 20 30 40 90 100 110 120 130 140 pF1KE9 -LISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVE :: .:: :::..:: :: ::.:.. . : :... ::::.: :.: ::: :.. NP_001 VLIPLVYLVVCVVGLLGNSLVIYVVLRHTA-SPSVTNVYILNLALADELFMLGLPFLAAQ 50 60 70 80 90 100 150 160 170 180 190 200 pF1KE9 NALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDC :::.. ::::. ::..: : ..:...:.: ::.::: :: .:. .: : : NP_001 NALSY-WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAP---- 110 120 130 140 150 210 220 230 240 250 260 pF1KE9 CGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQ :... . .:. .:.. :: ..:: . . : : ...:. . NP_001 -----------VARTVSAAVWVASAVVVLPVVVFSGVPR--GMSTCHMQWPEPAAA---- 160 170 180 190 200 270 280 290 300 310 320 pF1KE9 FWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRL : . . . ::: :: .: :::::.: . :.:: . : :. :: NP_001 -WRAGFIIYTAALGFFGPLLVICLCYLLIVVKV---RSAGRRVWA------PSCQRRRRS 210 220 230 240 250 330 340 350 360 370 pF1KE9 SK-VTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVP-FSQEYFLCQVYAFPVSVCLAH . ::. :. :: : :::.: .:. ... . : : ::: : :.: . NP_001 ERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFL--VVALP------Y 260 270 280 290 300 380 390 400 410 420 430 pF1KE9 SNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATT-KPEHEDQGLQAPAPPH .::: ::.:: .. .:..... .: : : . :..: .. : :.::. NP_001 ANSCANPILYGFLSYRFKQGFRRVLLR-PSRRVRSQEPTVGPPEKTEEEDEEEEDGEESR 310 320 330 340 350 360 440 450 460 pF1KE9 AAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY NP_001 EGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>NP_001044 (OMIM: 182455) somatostatin receptor type 5 (364 aa) initn: 490 init1: 152 opt: 325 Z-score: 330.1 bits: 70.0 E(88908): 1.3e-11 Smith-Waterman score: 552; 33.2% identity (56.5% similar) in 395 aa overlap (58-446:13-359) 30 40 50 60 70 80 pF1KE9 VPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGSGGAES----ADTEARVRIL ... :: :.: .. : . . .: NP_001 MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVL 10 20 30 40 90 100 110 120 130 140 pF1KE9 ISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENA . :.: .::: ::.:: ::.:.. . :. :... :::..: ..: ::: :..:: NP_001 VPVLYLLVCAAGLGGNTLVIYVVLRFAKM-KTVTNIYILNLAVADVLYMLGLPFLATQNA 50 60 70 80 90 100 150 160 170 180 190 200 pF1KE9 LDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCCG .: :::: ..:..: . ..:...::: ::.::: :: .:. :.: : : . : NP_001 ASF-WPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWR-RPR----- 110 120 130 140 150 210 220 230 240 250 260 pF1KE9 RSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQFW :: . :.:. ::: .:. :. : : . .:. . : .: NP_001 ---------VAKLASAAAWVLSLCMSLPLLVFAD-VQEGG--TCNASWPEPV-G----LW 160 170 180 190 270 280 290 300 310 320 pF1KE9 LGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRLSK ... ..::: :: .: :::::.: . ::::.. : . : : NP_001 GAVFIIYTAVLGFFAPLLVICLCYLLIVVKV---RAAGVRVGCV---------RRRSERK 200 210 220 230 240 330 340 350 360 370 380 pF1KE9 VTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSNSC ::. : .::: : :::: ... : :: . :: .: : : :...::: NP_001 VTRMVLVVVLVFAGCWLP-----FFTVNIVNLAVALPQEPASAGLYFF--VVILSYANSC 250 260 270 280 290 390 400 410 420 430 440 pF1KE9 LNPVLYCLVRREFRKALKSLL-WRIASPSITSMRPFTATT-KPEHEDQGLQAPAPPHAAA ::::: .. .::......: : .: . . :: .:.. : .: : : :: NP_001 ANPVLYGFLSDNFRQSFQKVLCLRKGSGA----KDADATEPRPDRIRQQQEATPPAHRAA 300 310 320 330 340 350 450 460 pF1KE9 EPDLLYYPPGVVVYSGGRYDLLPSSSAY :. NP_001 ANGLMQTSKL 360 469 residues in 1 query sequences 63214209 residues in 88908 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Sep 21 11:30:25 2017 done: Thu Sep 21 11:30:27 2017 Total Scan time: 9.910 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]