Result of FASTA (omim) for
pF1KE9527
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9527, 397 aa
1>>>pF1KE9527 397 - 397 aa - 397 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7229+/-0.000577; mu= 20.4796+/- 0.036
mean_var=127.1662+/-33.507, 0's: 0 Z-trim(107.3): 581 B-trim: 817 in 1/49
Lambda= 0.113734
statistics sampled from 14647 (15362) to 14647 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.509), E-opt: 0.2 (0.18), width: 16
Scan time: 5.510
The best scores are: opt bits E(85289)
NP_005233 (OMIM: 600933) proteinase-activated rece ( 397) 2559 432.5 8.8e-121
XP_016864712 (OMIM: 600933) PREDICTED: proteinase- ( 383) 2385 403.9 3.4e-112
NP_001983 (OMIM: 187930) proteinase-activated rece ( 425) 787 141.8 3.1e-33
NP_001243495 (OMIM: 601919) proteinase-activated r ( 352) 744 134.6 3.7e-31
NP_004092 (OMIM: 601919) proteinase-activated rece ( 374) 744 134.6 3.8e-31
NP_001298242 (OMIM: 187930) proteinase-activated r ( 304) 700 127.3 5.1e-29
XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 699 127.2 6.2e-29
XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 699 127.2 6.2e-29
XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 699 127.2 6.2e-29
XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 699 127.2 6.2e-29
XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 699 127.2 6.2e-29
NP_835230 (OMIM: 300525) P2Y purinoceptor 8 [Homo ( 359) 699 127.2 6.2e-29
XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 699 127.2 6.2e-29
XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 699 127.5 7.8e-29
XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 699 127.5 7.8e-29
NP_003941 (OMIM: 602779) proteinase-activated rece ( 385) 659 120.7 6.1e-27
NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 568 105.7 1.8e-22
NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 568 105.7 1.8e-22
NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 568 105.7 1.9e-22
XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 568 105.7 1.9e-22
NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 568 105.7 1.9e-22
NP_002554 (OMIM: 601167) P2Y purinoceptor 1 [Homo ( 373) 560 104.4 4.7e-22
XP_005260196 (OMIM: 602779) PREDICTED: proteinase- ( 273) 538 100.6 4.8e-21
XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 537 100.6 6.3e-21
XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 537 100.6 6.3e-21
XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 537 100.6 6.3e-21
XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 537 100.6 6.3e-21
NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 537 100.6 6.3e-21
NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 537 100.6 6.3e-21
NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo ( 365) 536 100.5 7.1e-21
NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 526 98.8 2.1e-20
NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 526 98.8 2.1e-20
NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 526 98.8 2.1e-20
NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 526 98.8 2.1e-20
NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 526 98.8 2.1e-20
NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 526 98.8 2.1e-20
NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 526 98.8 2.1e-20
NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 526 98.8 2.1e-20
NP_115942 (OMIM: 300903) probable G-protein couple ( 333) 523 98.3 2.9e-20
NP_005273 (OMIM: 600551) G-protein coupled recepto ( 362) 509 96.0 1.5e-19
XP_016882096 (OMIM: 600551) PREDICTED: G-protein c ( 362) 509 96.0 1.5e-19
XP_016882097 (OMIM: 600551) PREDICTED: G-protein c ( 362) 509 96.0 1.5e-19
NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 508 95.8 1.7e-19
NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 508 95.8 1.7e-19
NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 508 95.8 1.7e-19
NP_788086 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 497 94.1 6.1e-19
NP_788085 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 497 94.1 6.1e-19
NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 497 94.1 6.1e-19
NP_001158195 (OMIM: 173393) platelet-activating fa ( 342) 494 93.5 8.1e-19
NP_001158193 (OMIM: 173393) platelet-activating fa ( 342) 494 93.5 8.1e-19
>>NP_005233 (OMIM: 600933) proteinase-activated receptor (397 aa)
initn: 2559 init1: 2559 opt: 2559 Z-score: 2289.4 bits: 432.5 E(85289): 8.8e-121
Smith-Waterman score: 2559; 99.7% identity (100.0% similar) in 397 aa overlap (1-397:1-397)
10 20 30 40 50 60
pF1KE9 MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 MGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 NYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVSVLAMYLICF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_005 NYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 TPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALL
310 320 330 340 350 360
370 380 390
pF1KE9 CRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
:::::::::::::::::::::::::::::::::::::
NP_005 CRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
370 380 390
>>XP_016864712 (OMIM: 600933) PREDICTED: proteinase-acti (383 aa)
initn: 2385 init1: 2385 opt: 2385 Z-score: 2135.3 bits: 403.9 E(85289): 3.4e-112
Smith-Waterman score: 2385; 99.2% identity (100.0% similar) in 371 aa overlap (27-397:13-383)
10 20 30 40 50 60
pF1KE9 MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFS
.::.::::::::::::::::::::::::::::::
XP_016 MSFKVGNLKFRSKGTSRSSKGRSLIGKVDGTSHVTGKGVTVETVFS
10 20 30 40
70 80 90 100 110 120
pF1KE9 VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 MGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMF
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 NYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVSVLAMYLICF
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_016 NYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICF
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE9 TPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALL
290 300 310 320 330 340
370 380 390
pF1KE9 CRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
:::::::::::::::::::::::::::::::::::::
XP_016 CRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
350 360 370 380
>>NP_001983 (OMIM: 187930) proteinase-activated receptor (425 aa)
initn: 717 init1: 473 opt: 787 Z-score: 717.8 bits: 141.8 E(85289): 3.1e-33
Smith-Waterman score: 787; 40.1% identity (70.4% similar) in 334 aa overlap (61-389:88-418)
40 50 60 70 80 90
pF1KE9 RSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGL
..: ... ::.. :.:.: ::: ::::.:
NP_001 DEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSL
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE9 PSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNV
: : ::. ::... : :.:::.:: .:: ::.: : .:.::.:.. :..: .: ::
NP_001 PLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRF
120 130 140 150 160 170
160 170 180 190 200
pF1KE9 LIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGH-SRKKANIAIGISLAIWLLILLVTIPL
. . :: ::: :::.:: .:..:. ..: :: : . . : :::: : . ..::
NP_001 VTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPL
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE9 YVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLF-PAFLTASAYVLMIRM
. .::: .:.:::::::::: : :: : .. :..: .::.: : .... :: .::
NP_001 LLKEQTIQVPGLNITTCHDVLNETLLEG-YYAYYFSAFSAVFFFVPLIISTVCYVSIIRC
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE9 LRSSAMDENSEKKRKRAIKLIVSVLAMYLICFTPSNLLLVVHY-FLIKSQGQSHVYALYI
: :::. . : :..::. : ..:. ...::: :.:.::..:: :: ... .: :.
NP_001 LSSSAVANRS--KKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYL
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE9 VALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVS--LTSKKHSRKSSS
. .:.:... ::::..::..: . . .. . : :. .... : : ..: . ::.
NP_001 LCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSN
360 370 380 390 400 410
390
pF1KE9 YSSSSTTVKTSY
..:
NP_001 LNNSIYKKLLT
420
>>NP_001243495 (OMIM: 601919) proteinase-activated recep (352 aa)
initn: 533 init1: 301 opt: 744 Z-score: 680.4 bits: 134.6 E(85289): 3.7e-31
Smith-Waterman score: 744; 38.4% identity (71.9% similar) in 302 aa overlap (61-359:58-350)
40 50 60 70 80 90
pF1KE9 RSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGL
: . . . ::..:.: ..: .: .:::::.
NP_001 EFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGV
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE9 PSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNV
:.:...::...:::.. .:.: .:::.::.: . .:.:::::..::::..::.:: .
NP_001 PANAVTLWMLFFRTRSICTTVFY-TNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRA
90 100 110 120 130 140
160 170 180 190 200
pF1KE9 LIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGH-SRKKANIAIGISLAIWLLILLVTIPL
.::::::::::...:.:..:: .::.:. . . : . :. .: ..: .:.
NP_001 TTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPF
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE9 YVVKQTIFIPALNITTCHDVLPEQLLVGDMFN--YFLSLAIGVFLFPAFLTASAYVLMIR
...:: .. .::::::: . .. :. ::.:::. ::.: : :. .::
NP_001 FILKQEYYLVQPDITTCHDV-HNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIR
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE9 MLRSSAMDENSEKKRKRAIKLIVSVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYI
: .:.: .. .: . .:... :::.:::..:..:. .. . .: .:.
NP_001 TL--NAYD----HRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYL
270 280 290 300 310
330 340 350 360 370 380
pF1KE9 VALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYS
.::::..::::.:::.:...:. :.:. :
NP_001 IALCLGSLNSCLDPFLYFLMSKT-RNHSTAYLTK
320 330 340 350
390
pF1KE9 SSSTTVKTSY
>>NP_004092 (OMIM: 601919) proteinase-activated receptor (374 aa)
initn: 533 init1: 301 opt: 744 Z-score: 680.2 bits: 134.6 E(85289): 3.8e-31
Smith-Waterman score: 744; 38.4% identity (71.9% similar) in 302 aa overlap (61-359:80-372)
40 50 60 70 80 90
pF1KE9 RSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGL
: . . . ::..:.: ..: .: .:::::.
NP_004 EFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGV
50 60 70 80 90 100
100 110 120 130 140 150
pF1KE9 PSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNV
:.:...::...:::.. .:.: .:::.::.: . .:.:::::..::::..::.:: .
NP_004 PANAVTLWMLFFRTRSICTTVFY-TNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRA
110 120 130 140 150 160
160 170 180 190 200
pF1KE9 LIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGH-SRKKANIAIGISLAIWLLILLVTIPL
.::::::::::...:.:..:: .::.:. . . : . :. .: ..: .:.
NP_004 TTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPF
170 180 190 200 210 220
210 220 230 240 250 260
pF1KE9 YVVKQTIFIPALNITTCHDVLPEQLLVGDMFN--YFLSLAIGVFLFPAFLTASAYVLMIR
...:: .. .::::::: . .. :. ::.:::. ::.: : :. .::
NP_004 FILKQEYYLVQPDITTCHDV-HNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIR
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE9 MLRSSAMDENSEKKRKRAIKLIVSVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYI
: .:.: .. .: . .:... :::.:::..:..:. .. . .: .:.
NP_004 TL--NAYD----HRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYL
290 300 310 320 330 340
330 340 350 360 370 380
pF1KE9 VALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYS
.::::..::::.:::.:...:. :.:. :
NP_004 IALCLGSLNSCLDPFLYFLMSKT-RNHSTAYLTK
350 360 370
390
pF1KE9 SSSTTVKTSY
>>NP_001298242 (OMIM: 187930) proteinase-activated recep (304 aa)
initn: 613 init1: 392 opt: 700 Z-score: 642.0 bits: 127.3 E(85289): 5.1e-29
Smith-Waterman score: 700; 39.3% identity (69.7% similar) in 300 aa overlap (95-389:1-297)
70 80 90 100 110 120
pF1KE9 SASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLS
::. ::... : :.:::.:: .:: ::.:
NP_001 MAIVVFILKMKVKKPAVVYMLHLATADVLF
10 20 30
130 140 150 160 170 180
pF1KE9 VIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGH-
: .:.::.:.. :..: .: :: . . :: ::: :::.:: .:..:. ..: ::
NP_001 VSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSL
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE9 SRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYF
: . . : :::: : . ..:: . .::: .:.:::::::::: : :: : .. :.
NP_001 SWRTLGRASFTCLAIWALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEG-YYAYY
100 110 120 130 140
250 260 270 280 290 300
pF1KE9 LSLAIGVFLF-PAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVSVLAMYLICFTP
.: .::.: : .... :: .:: : :::. . : :..::. : ..:. ...::: :
NP_001 FSAFSAVFFFVPLIISTVCYVSIIRCLSSSAVANRS--KKSRALFLSAAVFCIFIICFGP
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE9 SNLLLVVHY-FLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLC
.:.::..:: :: ... .: :.. .:.:... ::::..::..: . . .. . : :
NP_001 TNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCC
210 220 230 240 250 260
370 380 390
pF1KE9 RSVRTVKQMQVS--LTSKKHSRKSSSYSSSSTTVKTSY
. .... : : ..: . ::. ..:
NP_001 KESSDPSSYNSSGQLMASKMDTCSSNLNNSIYKKLLT
270 280 290 300
>>XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa)
initn: 666 init1: 337 opt: 699 Z-score: 640.4 bits: 127.2 E(85289): 6.2e-29
Smith-Waterman score: 699; 34.9% identity (66.9% similar) in 338 aa overlap (62-395:10-335)
40 50 60 70 80 90
pF1KE9 SSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLP
:. . ..: . .: ::.::..: .:..:
XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIP
10 20 30
100 110 120 130 140 150
pF1KE9 SNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVL
.: ..:::. : . :.::.: ::...::. . .:..: :: . ..:..: ::::.
XP_011 GNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVV
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE9 IGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSR-KKANIAIGISLAIWLLILLVTIPLY
::.::: ::: :::.::.:. .. :.. .: .. :.. . :::.: . ::
XP_011 TVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLA
100 110 120 130 140 150
220 230 240 250 260
pF1KE9 VVKQTIFIPALNITTCHDVLPEQLLVG-DMFNYFL-SLAIGVFLFPAFLTASAYV-LMIR
. : . ::.: :: ::: .: . :. :: .. : .::.: .:.. :. ...
XP_011 RTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE9 MLRSSAMDENSEKKRKRAIKLIVSVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYI
.::. . .....:.::. : . :: .. ::.:.:..:..: :.:. : .:
XP_011 LLRTE--EAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSY-YHVYK
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE9 VALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYS
..:::: ::.:.:::::::.:..:. . .. : :: : . .:. : .:
XP_011 LTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVP---------RDTLDTRRESLFS
280 290 300 310 320
390
pF1KE9 SSSTTVKTSY
. .:.:..
XP_011 ARTTSVRSEAGAHPEGMEGATRPGLQRQESVF
330 340 350
>>XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa)
initn: 666 init1: 337 opt: 699 Z-score: 640.4 bits: 127.2 E(85289): 6.2e-29
Smith-Waterman score: 699; 34.9% identity (66.9% similar) in 338 aa overlap (62-395:10-335)
40 50 60 70 80 90
pF1KE9 SSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLP
:. . ..: . .: ::.::..: .:..:
XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIP
10 20 30
100 110 120 130 140 150
pF1KE9 SNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVL
.: ..:::. : . :.::.: ::...::. . .:..: :: . ..:..: ::::.
XP_011 GNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVV
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE9 IGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSR-KKANIAIGISLAIWLLILLVTIPLY
::.::: ::: :::.::.:. .. :.. .: .. :.. . :::.: . ::
XP_011 TVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLA
100 110 120 130 140 150
220 230 240 250 260
pF1KE9 VVKQTIFIPALNITTCHDVLPEQLLVG-DMFNYFL-SLAIGVFLFPAFLTASAYV-LMIR
. : . ::.: :: ::: .: . :. :: .. : .::.: .:.. :. ...
XP_011 RTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE9 MLRSSAMDENSEKKRKRAIKLIVSVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYI
.::. . .....:.::. : . :: .. ::.:.:..:..: :.:. : .:
XP_011 LLRTE--EAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSY-YHVYK
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE9 VALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYS
..:::: ::.:.:::::::.:..:. . .. : :: : . .:. : .:
XP_011 LTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVP---------RDTLDTRRESLFS
280 290 300 310 320
390
pF1KE9 SSSTTVKTSY
. .:.:..
XP_011 ARTTSVRSEAGAHPEGMEGATRPGLQRQESVF
330 340 350
>>XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa)
initn: 666 init1: 337 opt: 699 Z-score: 640.4 bits: 127.2 E(85289): 6.2e-29
Smith-Waterman score: 699; 34.9% identity (66.9% similar) in 338 aa overlap (62-395:10-335)
40 50 60 70 80 90
pF1KE9 SSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLP
:. . ..: . .: ::.::..: .:..:
XP_005 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIP
10 20 30
100 110 120 130 140 150
pF1KE9 SNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVL
.: ..:::. : . :.::.: ::...::. . .:..: :: . ..:..: ::::.
XP_005 GNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVV
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE9 IGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSR-KKANIAIGISLAIWLLILLVTIPLY
::.::: ::: :::.::.:. .. :.. .: .. :.. . :::.: . ::
XP_005 TVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLA
100 110 120 130 140 150
220 230 240 250 260
pF1KE9 VVKQTIFIPALNITTCHDVLPEQLLVG-DMFNYFL-SLAIGVFLFPAFLTASAYV-LMIR
. : . ::.: :: ::: .: . :. :: .. : .::.: .:.. :. ...
XP_005 RTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE9 MLRSSAMDENSEKKRKRAIKLIVSVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYI
.::. . .....:.::. : . :: .. ::.:.:..:..: :.:. : .:
XP_005 LLRTE--EAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSY-YHVYK
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE9 VALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYS
..:::: ::.:.:::::::.:..:. . .. : :: : . .:. : .:
XP_005 LTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVP---------RDTLDTRRESLFS
280 290 300 310 320
390
pF1KE9 SSSTTVKTSY
. .:.:..
XP_005 ARTTSVRSEAGAHPEGMEGATRPGLQRQESVF
330 340 350
>>XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa)
initn: 666 init1: 337 opt: 699 Z-score: 640.4 bits: 127.2 E(85289): 6.2e-29
Smith-Waterman score: 699; 34.9% identity (66.9% similar) in 338 aa overlap (62-395:10-335)
40 50 60 70 80 90
pF1KE9 SSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLP
:. . ..: . .: ::.::..: .:..:
XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIP
10 20 30
100 110 120 130 140 150
pF1KE9 SNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVL
.: ..:::. : . :.::.: ::...::. . .:..: :: . ..:..: ::::.
XP_011 GNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVV
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE9 IGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSR-KKANIAIGISLAIWLLILLVTIPLY
::.::: ::: :::.::.:. .. :.. .: .. :.. . :::.: . ::
XP_011 TVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLA
100 110 120 130 140 150
220 230 240 250 260
pF1KE9 VVKQTIFIPALNITTCHDVLPEQLLVG-DMFNYFL-SLAIGVFLFPAFLTASAYV-LMIR
. : . ::.: :: ::: .: . :. :: .. : .::.: .:.. :. ...
XP_011 RTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE9 MLRSSAMDENSEKKRKRAIKLIVSVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYI
.::. . .....:.::. : . :: .. ::.:.:..:..: :.:. : .:
XP_011 LLRTE--EAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSY-YHVYK
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE9 VALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYS
..:::: ::.:.:::::::.:..:. . .. : :: : . .:. : .:
XP_011 LTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVP---------RDTLDTRRESLFS
280 290 300 310 320
390
pF1KE9 SSSTTVKTSY
. .:.:..
XP_011 ARTTSVRSEAGAHPEGMEGATRPGLQRQESVF
330 340 350
397 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:31:57 2016 done: Tue Nov 8 17:31:58 2016
Total Scan time: 5.510 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]