FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE9532, 370 aa 1>>>pF1KE9532 370 - 370 aa - 370 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5852+/-0.000437; mu= 20.6845+/- 0.027 mean_var=125.9998+/-32.842, 0's: 0 Z-trim(111.1): 734 B-trim: 1001 in 1/48 Lambda= 0.114259 statistics sampled from 18721 (19596) to 18721 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.59), E-opt: 0.2 (0.23), width: 16 Scan time: 7.280 The best scores are: opt bits E(85289) XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 2450 416.0 6.9e-116 NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 2450 416.0 6.9e-116 NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 2450 416.0 6.9e-116 NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 2450 416.0 6.9e-116 XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 2450 416.0 7.1e-116 XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 2450 416.0 7.1e-116 XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 2450 416.0 7.1e-116 NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 2450 416.0 7.2e-116 NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 2400 407.7 2.1e-113 XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 2400 407.7 2.1e-113 NP_001305784 (OMIM: 602548) nociceptin receptor is ( 341) 1918 328.2 1.7e-89 XP_011527132 (OMIM: 602548) PREDICTED: nociceptin ( 289) 1897 324.7 1.7e-88 NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 1288 224.5 3.2e-58 NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 1288 224.5 3.3e-58 NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 1288 224.5 3.3e-58 NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 1288 224.5 3.3e-58 NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 1288 224.5 3.3e-58 NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 1288 224.5 3.3e-58 NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 1288 224.5 3.4e-58 NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 1288 224.5 3.4e-58 NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 1288 224.5 3.4e-58 NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 1288 224.6 3.5e-58 NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 1288 224.6 3.7e-58 NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 1288 224.6 3.7e-58 NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 1259 219.7 8.8e-57 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 1259 219.7 9.2e-57 NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 1250 218.2 2.4e-56 NP_001269833 (OMIM: 165196) kappa-type opioid rece ( 291) 1157 202.7 8.8e-52 NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 1152 201.9 1.6e-51 NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 1132 198.6 1.5e-50 NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 1132 198.6 1.6e-50 NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 1132 198.6 1.6e-50 NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 1132 198.6 1.6e-50 XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 1132 198.6 1.6e-50 NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 1132 198.6 1.6e-50 XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50 XP_016866392 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50 XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50 XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50 XP_016866394 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50 XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50 XP_011534153 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 841 150.8 4.9e-36 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 825 148.2 3.1e-35 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 795 143.2 9.2e-34 NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 789 142.2 1.8e-33 NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 789 142.2 1.8e-33 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 787 142.0 2.4e-33 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 787 142.0 2.4e-33 XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 787 142.0 2.4e-33 >>XP_016883343 (OMIM: 602548) PREDICTED: nociceptin rece (370 aa) initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.5 bits: 416.0 E(85289): 6.9e-116 Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370) 10 20 30 40 50 60 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC 310 320 330 340 350 360 370 pF1KE9 KTSETVPRPA :::::::::: XP_016 KTSETVPRPA 370 >>NP_000904 (OMIM: 602548) nociceptin receptor isoform 1 (370 aa) initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.5 bits: 416.0 E(85289): 6.9e-116 Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370) 10 20 30 40 50 60 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC 310 320 330 340 350 360 370 pF1KE9 KTSETVPRPA :::::::::: NP_000 KTSETVPRPA 370 >>NP_001186948 (OMIM: 602548) nociceptin receptor isofor (370 aa) initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.5 bits: 416.0 E(85289): 6.9e-116 Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370) 10 20 30 40 50 60 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC 310 320 330 340 350 360 370 pF1KE9 KTSETVPRPA :::::::::: NP_001 KTSETVPRPA 370 >>NP_872588 (OMIM: 602548) nociceptin receptor isoform 1 (370 aa) initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.5 bits: 416.0 E(85289): 6.9e-116 Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370) 10 20 30 40 50 60 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC 310 320 330 340 350 360 370 pF1KE9 KTSETVPRPA :::::::::: NP_872 KTSETVPRPA 370 >>XP_016883341 (OMIM: 602548) PREDICTED: nociceptin rece (388 aa) initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.3 bits: 416.0 E(85289): 7.1e-116 Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:19-388) 10 20 30 40 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH :::::::::::::::::::::::::::::::::::::::::: XP_016 MKLQVKLVPYRVDLQGSGMEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE9 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE9 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE9 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE9 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE9 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD 310 320 330 340 350 360 350 360 370 pF1KE9 VQVSDRVRSIAKDVALACKTSETVPRPA :::::::::::::::::::::::::::: XP_016 VQVSDRVRSIAKDVALACKTSETVPRPA 370 380 >>XP_016883342 (OMIM: 602548) PREDICTED: nociceptin rece (388 aa) initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.3 bits: 416.0 E(85289): 7.1e-116 Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:19-388) 10 20 30 40 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH :::::::::::::::::::::::::::::::::::::::::: XP_016 MKLQVKLVPYRVDLQGSGMEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE9 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE9 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE9 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE9 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE9 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD 310 320 330 340 350 360 350 360 370 pF1KE9 VQVSDRVRSIAKDVALACKTSETVPRPA :::::::::::::::::::::::::::: XP_016 VQVSDRVRSIAKDVALACKTSETVPRPA 370 380 >>XP_011527130 (OMIM: 602548) PREDICTED: nociceptin rece (388 aa) initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.3 bits: 416.0 E(85289): 7.1e-116 Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:19-388) 10 20 30 40 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH :::::::::::::::::::::::::::::::::::::::::: XP_011 MKLQVKLVPYRVDLQGSGMEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE9 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE9 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE9 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE9 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE9 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD 310 320 330 340 350 360 350 360 370 pF1KE9 VQVSDRVRSIAKDVALACKTSETVPRPA :::::::::::::::::::::::::::: XP_011 VQVSDRVRSIAKDVALACKTSETVPRPA 370 380 >>NP_001305782 (OMIM: 602548) nociceptin receptor isofor (399 aa) initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.2 bits: 416.0 E(85289): 7.2e-116 Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370) 10 20 30 40 50 60 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC 310 320 330 340 350 360 370 pF1KE9 KTSETVPRPA :::::::::: NP_001 KTSETVPRPAXLGVDLPMVPVSPQSPSTPNTELTQVTAL 370 380 390 >>NP_001305783 (OMIM: 602548) nociceptin receptor isofor (365 aa) initn: 1919 init1: 1919 opt: 2400 Z-score: 2157.0 bits: 407.7 E(85289): 2.1e-113 Smith-Waterman score: 2400; 98.6% identity (98.6% similar) in 370 aa overlap (1-370:1-365) 10 20 30 40 50 60 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN ::::::::::::: :::::::::::::::::::::::::::::::::::::::::: NP_001 VCVGGLLGNCLVM-----HTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN 70 80 90 100 110 130 140 150 160 170 180 pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC 300 310 320 330 340 350 370 pF1KE9 KTSETVPRPA :::::::::: NP_001 KTSETVPRPA 360 >>XP_016883344 (OMIM: 602548) PREDICTED: nociceptin rece (365 aa) initn: 1919 init1: 1919 opt: 2400 Z-score: 2157.0 bits: 407.7 E(85289): 2.1e-113 Smith-Waterman score: 2400; 98.6% identity (98.6% similar) in 370 aa overlap (1-370:1-365) 10 20 30 40 50 60 pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN ::::::::::::: :::::::::::::::::::::::::::::::::::::::::: XP_016 VCVGGLLGNCLVM-----HTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN 70 80 90 100 110 130 140 150 160 170 180 pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC 300 310 320 330 340 350 370 pF1KE9 KTSETVPRPA :::::::::: XP_016 KTSETVPRPA 360 370 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 13:00:01 2016 done: Sun Nov 6 13:00:02 2016 Total Scan time: 7.280 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]