FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9532, 370 aa
1>>>pF1KE9532 370 - 370 aa - 370 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5852+/-0.000437; mu= 20.6845+/- 0.027
mean_var=125.9998+/-32.842, 0's: 0 Z-trim(111.1): 734 B-trim: 1001 in 1/48
Lambda= 0.114259
statistics sampled from 18721 (19596) to 18721 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.59), E-opt: 0.2 (0.23), width: 16
Scan time: 7.280
The best scores are: opt bits E(85289)
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 2450 416.0 6.9e-116
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 2450 416.0 6.9e-116
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 2450 416.0 6.9e-116
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 2450 416.0 6.9e-116
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 2450 416.0 7.1e-116
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 2450 416.0 7.1e-116
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 2450 416.0 7.1e-116
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 2450 416.0 7.2e-116
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 2400 407.7 2.1e-113
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 2400 407.7 2.1e-113
NP_001305784 (OMIM: 602548) nociceptin receptor is ( 341) 1918 328.2 1.7e-89
XP_011527132 (OMIM: 602548) PREDICTED: nociceptin ( 289) 1897 324.7 1.7e-88
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 1288 224.5 3.2e-58
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 1288 224.5 3.3e-58
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 1288 224.5 3.3e-58
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 1288 224.5 3.3e-58
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 1288 224.5 3.3e-58
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 1288 224.5 3.3e-58
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 1288 224.5 3.4e-58
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 1288 224.5 3.4e-58
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 1288 224.5 3.4e-58
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 1288 224.6 3.5e-58
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 1288 224.6 3.7e-58
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 1288 224.6 3.7e-58
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 1259 219.7 8.8e-57
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 1259 219.7 9.2e-57
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 1250 218.2 2.4e-56
NP_001269833 (OMIM: 165196) kappa-type opioid rece ( 291) 1157 202.7 8.8e-52
NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 1152 201.9 1.6e-51
NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 1132 198.6 1.5e-50
NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 1132 198.6 1.6e-50
NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 1132 198.6 1.6e-50
NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 1132 198.6 1.6e-50
XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 1132 198.6 1.6e-50
NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 1132 198.6 1.6e-50
XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50
XP_016866392 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50
XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50
XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50
XP_016866394 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50
XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50
XP_011534153 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1132 198.7 1.7e-50
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 841 150.8 4.9e-36
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 825 148.2 3.1e-35
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 795 143.2 9.2e-34
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 789 142.2 1.8e-33
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 789 142.2 1.8e-33
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 787 142.0 2.4e-33
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 787 142.0 2.4e-33
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 787 142.0 2.4e-33
>>XP_016883343 (OMIM: 602548) PREDICTED: nociceptin rece (370 aa)
initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.5 bits: 416.0 E(85289): 6.9e-116
Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
310 320 330 340 350 360
370
pF1KE9 KTSETVPRPA
::::::::::
XP_016 KTSETVPRPA
370
>>NP_000904 (OMIM: 602548) nociceptin receptor isoform 1 (370 aa)
initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.5 bits: 416.0 E(85289): 6.9e-116
Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
310 320 330 340 350 360
370
pF1KE9 KTSETVPRPA
::::::::::
NP_000 KTSETVPRPA
370
>>NP_001186948 (OMIM: 602548) nociceptin receptor isofor (370 aa)
initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.5 bits: 416.0 E(85289): 6.9e-116
Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
310 320 330 340 350 360
370
pF1KE9 KTSETVPRPA
::::::::::
NP_001 KTSETVPRPA
370
>>NP_872588 (OMIM: 602548) nociceptin receptor isoform 1 (370 aa)
initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.5 bits: 416.0 E(85289): 6.9e-116
Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
310 320 330 340 350 360
370
pF1KE9 KTSETVPRPA
::::::::::
NP_872 KTSETVPRPA
370
>>XP_016883341 (OMIM: 602548) PREDICTED: nociceptin rece (388 aa)
initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.3 bits: 416.0 E(85289): 7.1e-116
Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:19-388)
10 20 30 40
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH
::::::::::::::::::::::::::::::::::::::::::
XP_016 MKLQVKLVPYRVDLQGSGMEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD
310 320 330 340 350 360
350 360 370
pF1KE9 VQVSDRVRSIAKDVALACKTSETVPRPA
::::::::::::::::::::::::::::
XP_016 VQVSDRVRSIAKDVALACKTSETVPRPA
370 380
>>XP_016883342 (OMIM: 602548) PREDICTED: nociceptin rece (388 aa)
initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.3 bits: 416.0 E(85289): 7.1e-116
Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:19-388)
10 20 30 40
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH
::::::::::::::::::::::::::::::::::::::::::
XP_016 MKLQVKLVPYRVDLQGSGMEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD
310 320 330 340 350 360
350 360 370
pF1KE9 VQVSDRVRSIAKDVALACKTSETVPRPA
::::::::::::::::::::::::::::
XP_016 VQVSDRVRSIAKDVALACKTSETVPRPA
370 380
>>XP_011527130 (OMIM: 602548) PREDICTED: nociceptin rece (388 aa)
initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.3 bits: 416.0 E(85289): 7.1e-116
Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:19-388)
10 20 30 40
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH
::::::::::::::::::::::::::::::::::::::::::
XP_011 MKLQVKLVPYRVDLQGSGMEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVF
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRD
310 320 330 340 350 360
350 360 370
pF1KE9 VQVSDRVRSIAKDVALACKTSETVPRPA
::::::::::::::::::::::::::::
XP_011 VQVSDRVRSIAKDVALACKTSETVPRPA
370 380
>>NP_001305782 (OMIM: 602548) nociceptin receptor isofor (399 aa)
initn: 2450 init1: 2450 opt: 2450 Z-score: 2201.2 bits: 416.0 E(85289): 7.2e-116
Smith-Waterman score: 2450; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
310 320 330 340 350 360
370
pF1KE9 KTSETVPRPA
::::::::::
NP_001 KTSETVPRPAXLGVDLPMVPVSPQSPSTPNTELTQVTAL
370 380 390
>>NP_001305783 (OMIM: 602548) nociceptin receptor isofor (365 aa)
initn: 1919 init1: 1919 opt: 2400 Z-score: 2157.0 bits: 407.7 E(85289): 2.1e-113
Smith-Waterman score: 2400; 98.6% identity (98.6% similar) in 370 aa overlap (1-370:1-365)
10 20 30 40 50 60
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_001 VCVGGLLGNCLVM-----HTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
70 80 90 100 110
130 140 150 160 170 180
pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
300 310 320 330 340 350
370
pF1KE9 KTSETVPRPA
::::::::::
NP_001 KTSETVPRPA
360
>>XP_016883344 (OMIM: 602548) PREDICTED: nociceptin rece (365 aa)
initn: 1919 init1: 1919 opt: 2400 Z-score: 2157.0 bits: 407.7 E(85289): 2.1e-113
Smith-Waterman score: 2400; 98.6% identity (98.6% similar) in 370 aa overlap (1-370:1-365)
10 20 30 40 50 60
pF1KE9 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_016 VCVGGLLGNCLVM-----HTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
70 80 90 100 110
130 140 150 160 170 180
pF1KE9 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE9 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
300 310 320 330 340 350
370
pF1KE9 KTSETVPRPA
::::::::::
XP_016 KTSETVPRPA
360
370 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:00:01 2016 done: Sun Nov 6 13:00:02 2016
Total Scan time: 7.280 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]