FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE9612, 312 aa 1>>>pF1KE9612 312 - 312 aa - 312 aa Library: /omim/omim.rfq.tfa 61573307 residues in 86401 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8856+/-0.00032; mu= 13.5556+/- 0.020 mean_var=82.9253+/-16.330, 0's: 0 Z-trim(115.9): 12 B-trim: 24 in 2/54 Lambda= 0.140842 statistics sampled from 26822 (26834) to 26822 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.311), width: 16 Scan time: 8.110 The best scores are: opt bits E(86401) NP_078846 (OMIM: 610181,610326) ribonuclease H2 su ( 312) 2045 425.0 9.7e-119 XP_006719930 (OMIM: 610181,610326) PREDICTED: ribo ( 306) 1900 395.5 7.1e-110 XP_011533533 (OMIM: 610181,610326) PREDICTED: ribo ( 259) 1652 345.1 9.1e-95 NP_001135751 (OMIM: 610181,610326) ribonuclease H2 ( 257) 1645 343.7 2.4e-94 XP_016876236 (OMIM: 610181,610326) PREDICTED: ribo ( 258) 1645 343.7 2.4e-94 XP_011533532 (OMIM: 610181,610326) PREDICTED: ribo ( 261) 1645 343.7 2.5e-94 XP_011533531 (OMIM: 610181,610326) PREDICTED: ribo ( 266) 1645 343.7 2.5e-94 XP_011533535 (OMIM: 610181,610326) PREDICTED: ribo ( 176) 1068 226.3 3.5e-59 >>NP_078846 (OMIM: 610181,610326) ribonuclease H2 subuni (312 aa) initn: 2045 init1: 2045 opt: 2045 Z-score: 2252.8 bits: 425.0 E(86401): 9.7e-119 Smith-Waterman score: 2045; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312) 10 20 30 40 50 60 pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF 250 260 270 280 290 300 310 pF1KE9 FGVKNKKKIGKV :::::::::::: NP_078 FGVKNKKKIGKV 310 >>XP_006719930 (OMIM: 610181,610326) PREDICTED: ribonucl (306 aa) initn: 1900 init1: 1900 opt: 1900 Z-score: 2093.7 bits: 395.5 E(86401): 7.1e-110 Smith-Waterman score: 1900; 100.0% identity (100.0% similar) in 291 aa overlap (22-312:16-306) 10 20 30 40 50 60 pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL ::::::::::::::::::::::::::::::::::::::: XP_006 MTQLKEFGLGSASQKEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 10 20 30 40 50 70 80 90 100 110 120 pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF 240 250 260 270 280 290 310 pF1KE9 FGVKNKKKIGKV :::::::::::: XP_006 FGVKNKKKIGKV 300 >>XP_011533533 (OMIM: 610181,610326) PREDICTED: ribonucl (259 aa) initn: 1645 init1: 1645 opt: 1652 Z-score: 1822.4 bits: 345.1 E(86401): 9.1e-95 Smith-Waterman score: 1652; 97.3% identity (98.8% similar) in 256 aa overlap (1-256:1-255) 10 20 30 40 50 60 pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF ::::::: :. ..:. XP_011 LPNPPSK-IQRMEKPIINHT 250 >>NP_001135751 (OMIM: 610181,610326) ribonuclease H2 sub (257 aa) initn: 1645 init1: 1645 opt: 1645 Z-score: 1814.8 bits: 343.7 E(86401): 2.4e-94 Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247) 10 20 30 40 50 60 pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF ::::::: NP_001 LPNPPSKMAAQRQKRGK 250 >>XP_016876236 (OMIM: 610181,610326) PREDICTED: ribonucl (258 aa) initn: 1645 init1: 1645 opt: 1645 Z-score: 1814.8 bits: 343.7 E(86401): 2.4e-94 Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247) 10 20 30 40 50 60 pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF ::::::: XP_016 LPNPPSKLGLPTGHFVKS 250 >>XP_011533532 (OMIM: 610181,610326) PREDICTED: ribonucl (261 aa) initn: 1645 init1: 1645 opt: 1645 Z-score: 1814.7 bits: 343.7 E(86401): 2.5e-94 Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247) 10 20 30 40 50 60 pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF ::::::: XP_011 LPNPPSKAATHSSSAAGMFIS 250 260 >>XP_011533531 (OMIM: 610181,610326) PREDICTED: ribonucl (266 aa) initn: 1645 init1: 1645 opt: 1645 Z-score: 1814.6 bits: 343.7 E(86401): 2.5e-94 Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247) 10 20 30 40 50 60 pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF ::::::: XP_011 LPNPPSKLGLPTGHFVMAAQRQKRGK 250 260 >>XP_011533535 (OMIM: 610181,610326) PREDICTED: ribonucl (176 aa) initn: 1068 init1: 1068 opt: 1068 Z-score: 1183.6 bits: 226.3 E(86401): 3.5e-59 Smith-Waterman score: 1068; 100.0% identity (100.0% similar) in 168 aa overlap (145-312:9-176) 120 130 140 150 160 170 pF1KE9 QVVVDNVFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQT :::::::::::::::::::::::::::::: XP_011 MGSFHFPSKGNPEIDNKKYYKYSKEKTLKWLEKKVNQT 10 20 30 180 190 200 210 220 230 pF1KE9 VAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKL 40 50 60 70 80 90 240 250 260 270 280 290 pF1KE9 PEPSASLPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEPSASLPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGM 100 110 120 130 140 150 300 310 pF1KE9 KSIDTFFGVKNKKKIGKV :::::::::::::::::: XP_011 KSIDTFFGVKNKKKIGKV 160 170 312 residues in 1 query sequences 61573307 residues in 86401 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Mar 10 10:44:10 2017 done: Fri Mar 10 10:44:11 2017 Total Scan time: 8.110 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]