Result of FASTA (omim) for pF1KE9612
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9612, 312 aa
  1>>>pF1KE9612     312 - 312 aa - 312 aa
Library: /omim/omim.rfq.tfa
  61573307 residues in 86401 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8856+/-0.00032; mu= 13.5556+/- 0.020
 mean_var=82.9253+/-16.330, 0's: 0 Z-trim(115.9): 12  B-trim: 24 in 2/54
 Lambda= 0.140842
 statistics sampled from 26822 (26834) to 26822 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.311), width:  16
 Scan time:  8.110

The best scores are:                                      opt bits E(86401)
NP_078846 (OMIM: 610181,610326) ribonuclease H2 su ( 312) 2045 425.0 9.7e-119
XP_006719930 (OMIM: 610181,610326) PREDICTED: ribo ( 306) 1900 395.5 7.1e-110
XP_011533533 (OMIM: 610181,610326) PREDICTED: ribo ( 259) 1652 345.1 9.1e-95
NP_001135751 (OMIM: 610181,610326) ribonuclease H2 ( 257) 1645 343.7 2.4e-94
XP_016876236 (OMIM: 610181,610326) PREDICTED: ribo ( 258) 1645 343.7 2.4e-94
XP_011533532 (OMIM: 610181,610326) PREDICTED: ribo ( 261) 1645 343.7 2.5e-94
XP_011533531 (OMIM: 610181,610326) PREDICTED: ribo ( 266) 1645 343.7 2.5e-94
XP_011533535 (OMIM: 610181,610326) PREDICTED: ribo ( 176) 1068 226.3 3.5e-59


>>NP_078846 (OMIM: 610181,610326) ribonuclease H2 subuni  (312 aa)
 initn: 2045 init1: 2045 opt: 2045  Z-score: 2252.8  bits: 425.0 E(86401): 9.7e-119
Smith-Waterman score: 2045; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312)

               10        20        30        40        50        60
pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF
              250       260       270       280       290       300

              310  
pF1KE9 FGVKNKKKIGKV
       ::::::::::::
NP_078 FGVKNKKKIGKV
              310  

>>XP_006719930 (OMIM: 610181,610326) PREDICTED: ribonucl  (306 aa)
 initn: 1900 init1: 1900 opt: 1900  Z-score: 2093.7  bits: 395.5 E(86401): 7.1e-110
Smith-Waterman score: 1900; 100.0% identity (100.0% similar) in 291 aa overlap (22-312:16-306)

               10        20        30        40        50        60
pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
                            :::::::::::::::::::::::::::::::::::::::
XP_006       MTQLKEFGLGSASQKEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF
          240       250       260       270       280       290    

              310  
pF1KE9 FGVKNKKKIGKV
       ::::::::::::
XP_006 FGVKNKKKIGKV
          300      

>>XP_011533533 (OMIM: 610181,610326) PREDICTED: ribonucl  (259 aa)
 initn: 1645 init1: 1645 opt: 1652  Z-score: 1822.4  bits: 345.1 E(86401): 9.1e-95
Smith-Waterman score: 1652; 97.3% identity (98.8% similar) in 256 aa overlap (1-256:1-255)

               10        20        30        40        50        60
pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF
       ::::::: :.  ..:.                                            
XP_011 LPNPPSK-IQRMEKPIINHT                                        
               250                                                 

>>NP_001135751 (OMIM: 610181,610326) ribonuclease H2 sub  (257 aa)
 initn: 1645 init1: 1645 opt: 1645  Z-score: 1814.8  bits: 343.7 E(86401): 2.4e-94
Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247)

               10        20        30        40        50        60
pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF
       :::::::                                                     
NP_001 LPNPPSKMAAQRQKRGK                                           
              250                                                  

>>XP_016876236 (OMIM: 610181,610326) PREDICTED: ribonucl  (258 aa)
 initn: 1645 init1: 1645 opt: 1645  Z-score: 1814.8  bits: 343.7 E(86401): 2.4e-94
Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247)

               10        20        30        40        50        60
pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF
       :::::::                                                     
XP_016 LPNPPSKLGLPTGHFVKS                                          
              250                                                  

>>XP_011533532 (OMIM: 610181,610326) PREDICTED: ribonucl  (261 aa)
 initn: 1645 init1: 1645 opt: 1645  Z-score: 1814.7  bits: 343.7 E(86401): 2.5e-94
Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247)

               10        20        30        40        50        60
pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF
       :::::::                                                     
XP_011 LPNPPSKAATHSSSAAGMFIS                                       
              250       260                                        

>>XP_011533531 (OMIM: 610181,610326) PREDICTED: ribonucl  (266 aa)
 initn: 1645 init1: 1645 opt: 1645  Z-score: 1814.6  bits: 343.7 E(86401): 2.5e-94
Smith-Waterman score: 1645; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247)

               10        20        30        40        50        60
pF1KE9 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF
       :::::::                                                     
XP_011 LPNPPSKLGLPTGHFVMAAQRQKRGK                                  
              250       260                                        

>>XP_011533535 (OMIM: 610181,610326) PREDICTED: ribonucl  (176 aa)
 initn: 1068 init1: 1068 opt: 1068  Z-score: 1183.6  bits: 226.3 E(86401): 3.5e-59
Smith-Waterman score: 1068; 100.0% identity (100.0% similar) in 168 aa overlap (145-312:9-176)

          120       130       140       150       160       170    
pF1KE9 QVVVDNVFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQT
                                     ::::::::::::::::::::::::::::::
XP_011                       MGSFHFPSKGNPEIDNKKYYKYSKEKTLKWLEKKVNQT
                                     10        20        30        

          180       190       200       210       220       230    
pF1KE9 VAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKL
       40        50        60        70        80        90        

          240       250       260       270       280       290    
pF1KE9 PEPSASLPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPSASLPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGM
      100       110       120       130       140       150        

          300       310  
pF1KE9 KSIDTFFGVKNKKKIGKV
       ::::::::::::::::::
XP_011 KSIDTFFGVKNKKKIGKV
      160       170      




312 residues in 1 query   sequences
61573307 residues in 86401 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Mar 10 10:44:10 2017 done: Fri Mar 10 10:44:11 2017
 Total Scan time:  8.110 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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