FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE9630, 1085 aa 1>>>pF1KE9630 1085 - 1085 aa - 1085 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3859+/-0.00115; mu= 8.2189+/- 0.069 mean_var=174.1314+/-35.876, 0's: 0 Z-trim(107.2): 40 B-trim: 136 in 1/53 Lambda= 0.097193 statistics sampled from 9388 (9408) to 9388 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.289), width: 16 Scan time: 3.720 The best scores are: opt bits E(32554) CCDS33273.1 BUB1 gene_id:699|Hs108|chr2 (1085) 7305 1037.7 0 CCDS62984.1 BUB1 gene_id:699|Hs108|chr2 (1065) 7100 1009.0 0 CCDS62985.1 BUB1 gene_id:699|Hs108|chr2 (1028) 5858 834.8 0 CCDS10053.1 BUB1B gene_id:701|Hs108|chr15 (1050) 392 68.4 9.7e-11 >>CCDS33273.1 BUB1 gene_id:699|Hs108|chr2 (1085 aa) initn: 7305 init1: 7305 opt: 7305 Z-score: 5544.9 bits: 1037.7 E(32554): 0 Smith-Waterman score: 7305; 100.0% identity (100.0% similar) in 1085 aa overlap (1-1085:1-1085) 10 20 30 40 50 60 pF1KE9 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC 1030 1040 1050 1060 1070 1080 pF1KE9 KRSRK ::::: CCDS33 KRSRK >>CCDS62984.1 BUB1 gene_id:699|Hs108|chr2 (1065 aa) initn: 7100 init1: 7100 opt: 7100 Z-score: 5389.6 bits: 1009.0 E(32554): 0 Smith-Waterman score: 7109; 98.2% identity (98.2% similar) in 1085 aa overlap (1-1085:1-1065) 10 20 30 40 50 60 pF1KE9 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK ::::::::: ::::::::::::::::::::::::::::::: CCDS62 MDTPENVLQ--------------------YIQWVEENFPENKEYLITLLEHLMKEFLDKK 10 20 30 40 70 80 90 100 110 120 pF1KE9 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE9 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE9 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE9 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE9 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE9 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE9 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE9 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL 470 480 490 500 510 520 550 560 570 580 590 600 pF1KE9 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF 530 540 550 560 570 580 610 620 630 640 650 660 pF1KE9 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK 590 600 610 620 630 640 670 680 690 700 710 720 pF1KE9 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA 650 660 670 680 690 700 730 740 750 760 770 780 pF1KE9 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF 710 720 730 740 750 760 790 800 810 820 830 840 pF1KE9 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER 770 780 790 800 810 820 850 860 870 880 890 900 pF1KE9 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR 830 840 850 860 870 880 910 920 930 940 950 960 pF1KE9 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KE9 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KE9 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC 1010 1020 1030 1040 1050 1060 pF1KE9 KRSRK ::::: CCDS62 KRSRK >>CCDS62985.1 BUB1 gene_id:699|Hs108|chr2 (1028 aa) initn: 6906 init1: 5858 opt: 5858 Z-score: 4448.6 bits: 834.8 E(32554): 0 Smith-Waterman score: 6794; 94.7% identity (94.7% similar) in 1085 aa overlap (1-1085:1-1028) 10 20 30 40 50 60 pF1KE9 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR ::::::::::::::::::::::::::::::::::: CCDS62 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLL------------------------- 850 860 870 910 920 930 940 950 960 pF1KE9 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT :::::::::::::::::::::::::::: CCDS62 --------------------------------DDEDDLSAGLALIDLGQSIDMKLFPKGT 880 890 900 970 980 990 1000 1010 1020 pF1KE9 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR 910 920 930 940 950 960 1030 1040 1050 1060 1070 1080 pF1KE9 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC 970 980 990 1000 1010 1020 pF1KE9 KRSRK ::::: CCDS62 KRSRK >>CCDS10053.1 BUB1B gene_id:701|Hs108|chr15 (1050 aa) initn: 848 init1: 276 opt: 392 Z-score: 306.3 bits: 68.4 E(32554): 9.7e-11 Smith-Waterman score: 708; 23.4% identity (54.2% similar) in 1096 aa overlap (6-1065:53-1033) 10 20 30 pF1KE9 MDTPENVLQM----LEAHMQSYKGNDPLGEWERYI :.::. .: ... : ::::: :.::: CCDS10 ELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYI 30 40 50 60 70 80 40 50 60 70 80 pF1KE9 QWVEENFPEN-KEY-LITLLEHLMKEFLDKKKYHNDPRFISYCLKFAEYNSDLHQFFEFL .:.:.:.:.. :: . ::::. .. . .:.:..::::.. ::... .. ... .: CCDS10 SWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPLDMYSYL 90 100 110 120 130 140 90 100 110 120 130 140 pF1KE9 YNHGIGTLSSPLYIAWAGHLEAQGELQHASAVLQRGIQNQAEPREFLQQQYRLFQTRLTE .:.:::. . .::.:: . ::. ....:.:..:.:::..::: : ::.:.: ::.:... CCDS10 HNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSR 150 160 170 180 190 200 150 160 170 180 190 200 pF1KE9 THLPAQARTSEPLHNVQVLNQMITSKSNPGNNMACI-SKNQGSELSGVISSACDKESNME : : . : .:... . ..:. .: . ::.. . . .: . .. . CCDS10 QTLLALEKEEEE----EVFESSVPQRST----LAELKSKGKKTARAPIIRVGGALKAPSQ 210 220 230 240 250 210 220 230 240 250 260 pF1KE9 RRVITISKSEYSVHSSLASKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQW : . .. . . . :.. : . .. .: : :: .. . : CCDS10 NRGL---QNPFPQQMQNNSRITVFD----------ENADEASTAEL------SKPTVQPW 260 270 280 290 270 280 290 300 310 320 pF1KE9 VNEDRHYMKRKEANAFEEQLLKQKMDELHKKLHQVVETSHEDLPASQERSEVNPARMGPS . : : . : .. . . :. .. .: .:: : :. . : CCDS10 IAPP---MPRAKENELQAGPWNTGRSLEHRPRGNT--ASLIAVPA------VLPS-FTPY 300 310 320 330 340 330 340 350 360 370 380 pF1KE9 VGSQQELRAPCL-PVTYQQTPVNMEKNPREAPPVVPPLANAISAALVSPATSQSIAPPVP : .. : : . : . . .. .. . . :: . : .: .... . CCDS10 V--EETARQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKM---MY 350 360 370 380 390 390 400 410 420 430 440 pF1KE9 LKAQTVTD-SMFAVASKDAGCVNKSTHEFKPQSGAEIKEGCETHKVANTSSFHTTPNTSL : . . . :. : : ..: : ::. . : : :. .. . .: CCDS10 CKEKIYAGVGEFSFEEIRAEVFRK---KLKEQREAELLTSAE--KRAEMQKQIEEMEKKL 400 410 420 430 440 450 450 460 470 480 490 500 pF1KE9 GMVQATPSKV---QPSPTVHTKEALGFIMNMFQAPTLPDISDDKDEWQSLDQNEDAFEAQ .:.: .. : :. :::. . . .. .: .. ... : : : :.. CCDS10 KEIQTTQQERTGDQQEETMPTKETTKLQIAS-ESQKIPGMTLSSSVCQV---NCCARETS 460 470 480 490 500 510 520 530 540 550 pF1KE9 FQKNVRSSGAWGVNKIISSLSSAFHVFED---GNKENYGLP-QP-----KNKPTGARTFG . .:. : . .. : : .:.. ..:.: . : .: . .: .. . CCDS10 LAENI-----WQEQPHSKGPSVPFSIFDEFLLSEKKNKSPPADPPRVLAQRRPLAVLKTS 510 520 530 540 550 560 560 570 580 590 600 610 pF1KE9 ERSVSRLPSKPK--EEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDFTSAAQLASTPFH : .: .: .: : . .:. . :.: : :. :.:.. ::. ::...::::: CCDS10 ESITSNEDVSPDVCDEFTGIEPLSEDAIITGFR-NVTICPNPEDTCDFARAARFVSTPFH 570 580 590 600 610 620 620 630 640 650 660 670 pF1KE9 KLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEKSPKQALSSHMYS . . :.: : : : .. : .: .. . .:. . .:: CCDS10 E-----IMSLKD-------------LPSDPERLL-PEED---LDVKTSEDQQTACGTIYS 630 640 650 660 680 690 700 710 720 730 pF1KE9 ASL-LRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA-EWMQMSSLGT .: .. .: . ... .... .. ..:..: ..: :: : ..... : CCDS10 QTLSIKKLSP-----IIEDSREATHSSGFSGSSASVAST--SSIKCLQIPEKLELTNE-T 670 680 690 700 710 740 750 760 770 780 pF1KE9 VDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSK--LVY . : . .:: .. .::..: . .: .: . .: .. . :..::.. . CCDS10 SENP---TQSPWCSQYRRQLLKSLPELSASAELCIEDR-PMPKLEIEKEIELGNEDYCIK 720 730 740 750 760 790 800 810 820 830 840 pF1KE9 VHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHM ..:. : . . : . :.: . :.::.. ::.:::. .: :::. ...: CCDS10 REYLICED-YKLFWVAPR---NSA---ELTVIKVSSQPVPWDFYINLKLKERLNEDFDH- 770 780 790 800 810 820 850 860 870 880 890 900 pF1KE9 FMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQV : : . .:.: .. ..: . .. .: ... . . . ... . . .: ..:.. CCDS10 ---FCSCYQYQDGCIV---WHQYINCFTLQDLLQHS--EYITHEITVLIIYNLLTIVEML 830 840 850 860 870 910 920 930 940 950 960 pF1KE9 HDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCET : ::.:::..: .:: : . . : . . .: ..:.. :.:... . .:: CCDS10 HKAEIVHGDLSPRCLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRV--QLDVFT----L 880 890 900 910 920 970 980 990 1000 1010 1020 pF1KE9 SGFQCVEML------SNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRRL :::. :..: .: ::.: ::.: .. .:: ...: .:. : . .: CCDS10 SGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISEL 930 940 950 960 970 980 1030 1040 1050 1060 1070 pF1KE9 PHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQ---QHYTNKIRALRNRLIVLLLE ..::.:: .:: : . : : ... ::. : . :: CCDS10 KDGELWNKFFVRILNANDEATVSVLGELAAEMNGVFDTTFQSHLNKALWKVGKLTSPGAL 990 1000 1010 1020 1030 1040 1080 pF1KE9 CKRSRK CCDS10 LFQ 1050 1085 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 19:42:26 2016 done: Mon Nov 7 19:42:26 2016 Total Scan time: 3.720 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]