FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9630, 1085 aa
1>>>pF1KE9630 1085 - 1085 aa - 1085 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4869+/-0.000494; mu= 2.1565+/- 0.031
mean_var=225.2991+/-47.379, 0's: 0 Z-trim(115.1): 43 B-trim: 0 in 0/58
Lambda= 0.085447
statistics sampled from 25380 (25405) to 25380 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.298), width: 16
Scan time: 11.030
The best scores are: opt bits E(85289)
NP_004327 (OMIM: 602452) mitotic checkpoint serine (1085) 7305 914.8 0
NP_001265545 (OMIM: 602452) mitotic checkpoint ser (1065) 7100 889.5 0
NP_001265546 (OMIM: 602452) mitotic checkpoint ser (1028) 5858 736.4 2e-211
NP_001202 (OMIM: 114500,176430,257300,602860) mito (1050) 392 62.6 1.4e-08
>>NP_004327 (OMIM: 602452) mitotic checkpoint serine/thr (1085 aa)
initn: 7305 init1: 7305 opt: 7305 Z-score: 4880.6 bits: 914.8 E(85289): 0
Smith-Waterman score: 7305; 100.0% identity (100.0% similar) in 1085 aa overlap (1-1085:1-1085)
10 20 30 40 50 60
pF1KE9 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC
1030 1040 1050 1060 1070 1080
pF1KE9 KRSRK
:::::
NP_004 KRSRK
>>NP_001265545 (OMIM: 602452) mitotic checkpoint serine/ (1065 aa)
initn: 7100 init1: 7100 opt: 7100 Z-score: 4744.1 bits: 889.5 E(85289): 0
Smith-Waterman score: 7109; 98.2% identity (98.2% similar) in 1085 aa overlap (1-1085:1-1065)
10 20 30 40 50 60
pF1KE9 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK
::::::::: :::::::::::::::::::::::::::::::
NP_001 MDTPENVLQ--------------------YIQWVEENFPENKEYLITLLEHLMKEFLDKK
10 20 30 40
70 80 90 100 110 120
pF1KE9 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE9 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE9 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE9 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE9 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE9 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE9 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE9 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE9 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE9 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE9 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE9 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE9 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE9 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC
1010 1020 1030 1040 1050 1060
pF1KE9 KRSRK
:::::
NP_001 KRSRK
>>NP_001265546 (OMIM: 602452) mitotic checkpoint serine/ (1028 aa)
initn: 6906 init1: 5858 opt: 5858 Z-score: 3916.9 bits: 736.4 E(85289): 2e-211
Smith-Waterman score: 6794; 94.7% identity (94.7% similar) in 1085 aa overlap (1-1085:1-1028)
10 20 30 40 50 60
pF1KE9 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSEPLHNVQVLNQMITSKSNPGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMACISKNQGSELSGVISSACDKESNMERRVITISKSEYSVHSSLASKVDVEQVVMYCKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKEANAFEEQLLKQKMDELHKKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQVVETSHEDLPASQERSEVNPARMGPSVGSQQELRAPCLPVTYQQTPVNMEKNPREAPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVPPLANAISAALVSPATSQSIAPPVPLKAQTVTDSMFAVASKDAGCVNKSTHEFKPQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIKEGCETHKVANTSSFHTTPNTSLGMVQATPSKVQPSPTVHTKEALGFIMNMFQAPTL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDISDDKDEWQSLDQNEDAFEAQFQKNVRSSGAWGVNKIISSLSSAFHVFEDGNKENYGL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQPKNKPTGARTFGERSVSRLPSKPKEEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSAAQLASTPFHKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPKQALSSHMYSASLLRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWMQMSSLGTVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLGSKLVYVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMER
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMR
:::::::::::::::::::::::::::::::::::
NP_001 LKPSMQHMFMKFYSAHLFQNGSVLVGELYSYGTLL-------------------------
850 860 870
910 920 930 940 950 960
pF1KE9 MLYMIEQVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGT
::::::::::::::::::::::::::::
NP_001 --------------------------------DDEDDLSAGLALIDLGQSIDMKLFPKGT
880 890 900
970 980 990 1000 1010 1020
pF1KE9 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFTAKCETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFR
910 920 930 940 950 960
1030 1040 1050 1060 1070 1080
pF1KE9 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQQHYTNKIRALRNRLIVLLLEC
970 980 990 1000 1010 1020
pF1KE9 KRSRK
:::::
NP_001 KRSRK
>>NP_001202 (OMIM: 114500,176430,257300,602860) mitotic (1050 aa)
initn: 848 init1: 276 opt: 392 Z-score: 275.2 bits: 62.6 E(85289): 1.4e-08
Smith-Waterman score: 714; 23.6% identity (54.1% similar) in 1097 aa overlap (6-1065:53-1033)
10 20 30
pF1KE9 MDTPENVLQM----LEAHMQSYKGNDPLGEWERYI
:.::. .: ... : ::::: :.:::
NP_001 ELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYI
30 40 50 60 70 80
40 50 60 70 80
pF1KE9 QWVEENFPEN-KEY-LITLLEHLMKEFLDKKKYHNDPRFISYCLKFAEYNSDLHQFFEFL
.:.:.:.:.. :: . ::::. .. . .:.:..::::.. ::... .. ... .:
NP_001 SWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPLDMYSYL
90 100 110 120 130 140
90 100 110 120 130 140
pF1KE9 YNHGIGTLSSPLYIAWAGHLEAQGELQHASAVLQRGIQNQAEPREFLQQQYRLFQTRLTE
.:.:::. . .::.:: . ::. ....:.:..:.:::..::: : ::.:.: ::.:...
NP_001 HNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSR
150 160 170 180 190 200
150 160 170 180 190 200
pF1KE9 THLPAQARTSEPLHNVQVLNQMITSKSNPGNNMACI-SKNQGSELSGVISSACDKESNME
: : . : .:... . ..:. .: . ::.. . . .: . .. .
NP_001 QTLLALEKEEEE----EVFESSVPQRST----LAELKSKGKKTARAPIIRVGGALKAPSQ
210 220 230 240 250
210 220 230 240 250 260
pF1KE9 RRVITISKSEYSVHSSLASKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQW
: . .. . . . :.. : . .. .: : :: .. . :
NP_001 NRGL---QNPFPQQMQNNSRITVFD----------ENADEASTAEL------SKPTVQPW
260 270 280 290
270 280 290 300 310 320
pF1KE9 VNEDRHYMKRKEANAFEEQLLKQKMDELHKKLHQVVETSHEDLPASQERSEVNPARMGPS
. : : . : .. . . :. .. .: .:: : :. . :
NP_001 IAPP---MPRAKENELQAGPWNTGRSLEHRPRGNT--ASLIAVPA------VLPS-FTPY
300 310 320 330 340
330 340 350 360 370 380
pF1KE9 V--GSQQELRAPCLPVTYQQTPVNMEKNPREAPPVVPPLANAISAALVSPATSQSIAPPV
: .:: . .:: . .. .: .: :: . : .: .... .
NP_001 VEETAQQPVMTPCKIEPSINHILSTRKPGKEEGD---PLQRVQSHQQASEEKKEKM---M
350 360 370 380 390
390 400 410 420 430 440
pF1KE9 PLKAQTVTD-SMFAVASKDAGCVNKSTHEFKPQSGAEIKEGCETHKVANTSSFHTTPNTS
: . . . :. : : ..: : ::. . : : :. .. . .
NP_001 YCKEKIYAGVGEFSFEEIRAEVFRK---KLKEQREAELLTSAE--KRAEMQKQIEEMEKK
400 410 420 430 440 450
450 460 470 480 490 500
pF1KE9 LGMVQATPSKV---QPSPTVHTKEALGFIMNMFQAPTLPDISDDKDEWQSLDQNEDAFEA
: .:.: .. : :. :::. . . .. .: .. ... : : : :.
NP_001 LKEIQTTQQERTGDQQEETMPTKETTKLQIAS-ESQKIPGMTLSSSVCQV---NCCARET
460 470 480 490 500
510 520 530 540 550
pF1KE9 QFQKNVRSSGAWGVNKIISSLSSAFHVFED---GNKENYGLP-QP-----KNKPTGARTF
.. .:. : . .. : : .:.. ..:.: . : .: . .: ..
NP_001 SLAENI-----WQEQPHSKGPSVPFSIFDEFLLSEKKNKSPPADPPRVLAQRRPLAVLKT
510 520 530 540 550 560
560 570 580 590 600 610
pF1KE9 GERSVSRLPSKPK--EEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDFTSAAQLASTPF
.: .: .: .: : . .:. . :.: : :. :.:.. ::. ::...::::
NP_001 SESITSNEDVSPDVCDEFTGIEPLSEDAIITGFR-NVTICPNPEDTCDFARAARFVSTPF
570 580 590 600 610 620
620 630 640 650 660 670
pF1KE9 HKLPVESVHILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEKSPKQALSSHMY
:. . :.: : : : .. : .: .. . .:. . .:
NP_001 HE-----IMSLKD-------------LPSDPERLL-PEED---LDVKTSEDQQTACGTIY
630 640 650 660
680 690 700 710 720
pF1KE9 SASL-LRLSQPAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQA-EWMQMSSLG
: .: .. .: . ... .... .. ..:..: ..: :: : .....
NP_001 SQTLSIKKLSP-----IIEDSREATHSSGFSGSSASVAST--SSIKCLQIPEKLELTNE-
670 680 690 700 710
730 740 750 760 770 780
pF1KE9 TVDAPNFIVGNPWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSK--LV
: . : . .:: .. .::..: . .: .: . .: .. . :..::.. .
NP_001 TSENP---TQSPWCSQYRRQLLKSLPELSASAELCIEDR-PMPKLEIEKEIELGNEDYCI
720 730 740 750 760
790 800 810 820 830 840
pF1KE9 YVHHLLGEGAFAQVYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQH
..:. : . . : . :.: . :.::.. ::.:::. .: :::. ...:
NP_001 KREYLICED-YKLFWVAPR---NSA---ELTVIKVSSQPVPWDFYINLKLKERLNEDFDH
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE9 MFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQ
: : . .:.: .. ..: . .. .: ... . . . ... . . .: ..:.
NP_001 ----FCSCYQYQDGCIV---WHQYINCFTLQDLLQHS--EYITHEITVLIIYNLLTIVEM
830 840 850 860 870
910 920 930 940 950 960
pF1KE9 VHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCE
.: ::.:::..: .:: : . . : . . .: ..:.. :.:... . .::
NP_001 LHKAEIVHGDLSPRCLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRV--QLDVFT----
880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE9 TSGFQCVEML------SNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRR
:::. :..: .: ::.: ::.: .. .:: ...: .:. : . .
NP_001 LSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISE
930 940 950 960 970 980
1030 1040 1050 1060 1070
pF1KE9 LPHLDMWNEFFHVMLNIPDCHHLPSLDLLRQKLKKVFQ---QHYTNKIRALRNRLIVLLL
: ..::.:: .:: : . : : ... ::. : . ::
NP_001 LKDGELWNKFFVRILNANDEATVSVLGELAAEMNGVFDTTFQSHLNKALWKVGKLTSPGA
990 1000 1010 1020 1030 1040
1080
pF1KE9 ECKRSRK
NP_001 LLFQ
1050
1085 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:42:27 2016 done: Mon Nov 7 19:42:28 2016
Total Scan time: 11.030 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]