FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE9636, 1559 aa 1>>>pF1KE9636 1559 - 1559 aa - 1559 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4310+/-0.000379; mu= 9.7965+/- 0.024 mean_var=178.1728+/-34.887, 0's: 0 Z-trim(119.1): 331 B-trim: 78 in 1/56 Lambda= 0.096085 statistics sampled from 32376 (32749) to 32376 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.384), width: 16 Scan time: 20.370 The best scores are: opt bits E(85289) NP_001269551 (OMIM: 300534,314690) lysine-specific (1559) 10626 1486.5 0 NP_004178 (OMIM: 300534,314690) lysine-specific de (1560) 10614 1484.8 0 XP_005262092 (OMIM: 300534,314690) PREDICTED: lysi (1557) 10577 1479.7 0 XP_011529127 (OMIM: 300534,314690) PREDICTED: lysi (1519) 9803 1372.4 0 XP_016885375 (OMIM: 300534,314690) PREDICTED: lysi (1451) 9800 1371.9 0 XP_011529130 (OMIM: 300534,314690) PREDICTED: lysi (1447) 9789 1370.4 0 XP_011529129 (OMIM: 300534,314690) PREDICTED: lysi (1452) 9788 1370.3 0 XP_011529128 (OMIM: 300534,314690) PREDICTED: lysi (1516) 9766 1367.2 0 XP_016885377 (OMIM: 300534,314690) PREDICTED: lysi (1448) 9763 1366.8 0 XP_016885378 (OMIM: 300534,314690) PREDICTED: lysi (1444) 9752 1365.3 0 XP_016885376 (OMIM: 300534,314690) PREDICTED: lysi (1449) 9751 1365.1 0 XP_011529131 (OMIM: 300534,314690) PREDICTED: lysi (1395) 9462 1325.1 0 XP_011529132 (OMIM: 300534,314690) PREDICTED: lysi (1395) 9462 1325.1 0 NP_001140174 (OMIM: 300534,314690) lysine-specific (1379) 8800 1233.3 0 XP_011529133 (OMIM: 300534,314690) PREDICTED: lysi (1232) 8372 1173.9 0 XP_011529126 (OMIM: 300534,314690) PREDICTED: lysi (1534) 7350 1032.3 0 NP_001140178 (OMIM: 415000,426000) lysine-specific (1482) 7291 1024.1 0 NP_004644 (OMIM: 415000,426000) lysine-specific de (1539) 7291 1024.2 0 XP_005262617 (OMIM: 415000,426000) PREDICTED: lysi (1494) 7288 1023.7 0 NP_001140177 (OMIM: 415000,426000) lysine-specific (1570) 6152 866.3 0 XP_011529770 (OMIM: 415000,426000) PREDICTED: lysi (1513) 4929 696.7 3.7e-199 NP_001300971 (OMIM: 605393) lysine-specific demeth (1580) 4344 615.6 9.9e-175 NP_001036068 (OMIM: 180202) lysine-specific demeth (1690) 4033 572.6 9.9e-162 XP_005262618 (OMIM: 415000,426000) PREDICTED: lysi (1462) 3772 536.3 6.8e-151 XP_011507392 (OMIM: 605393) PREDICTED: lysine-spec (1422) 3583 510.1 5.2e-143 XP_011507393 (OMIM: 605393) PREDICTED: lysine-spec (1422) 3583 510.1 5.2e-143 XP_011507394 (OMIM: 605393) PREDICTED: lysine-spec (1386) 3359 479.1 1.1e-133 XP_011507390 (OMIM: 605393) PREDICTED: lysine-spec (1499) 3359 479.1 1.2e-133 NP_006609 (OMIM: 605393) lysine-specific demethyla (1544) 3359 479.1 1.2e-133 NP_001155102 (OMIM: 616581) lysine-specific demeth ( 506) 491 81.2 2.4e-14 NP_060509 (OMIM: 609766) lysine-specific demethyla ( 523) 466 77.8 2.7e-13 XP_016858401 (OMIM: 609764) PREDICTED: lysine-spec ( 973) 452 76.0 1.7e-12 XP_005271413 (OMIM: 609764) PREDICTED: lysine-spec ( 973) 452 76.0 1.7e-12 XP_005271412 (OMIM: 609764) PREDICTED: lysine-spec (1064) 452 76.0 1.8e-12 XP_005271411 (OMIM: 609764) PREDICTED: lysine-spec (1064) 452 76.0 1.8e-12 NP_055478 (OMIM: 609764) lysine-specific demethyla (1064) 452 76.0 1.8e-12 XP_016869993 (OMIM: 605469) PREDICTED: lysine-spec ( 763) 444 74.8 3e-12 XP_016869992 (OMIM: 605469) PREDICTED: lysine-spec ( 793) 444 74.8 3.1e-12 XP_016869991 (OMIM: 605469) PREDICTED: lysine-spec ( 811) 444 74.8 3.2e-12 NP_001140167 (OMIM: 605469) lysine-specific demeth ( 813) 444 74.8 3.2e-12 NP_001140168 (OMIM: 605469) lysine-specific demeth ( 835) 444 74.9 3.3e-12 XP_016869988 (OMIM: 605469) PREDICTED: lysine-spec ( 949) 444 74.9 3.6e-12 XP_016869987 (OMIM: 605469) PREDICTED: lysine-spec ( 999) 444 74.9 3.8e-12 NP_001291268 (OMIM: 605469) lysine-specific demeth (1023) 444 74.9 3.8e-12 NP_055876 (OMIM: 605469) lysine-specific demethyla (1056) 444 74.9 3.9e-12 XP_006716804 (OMIM: 605469) PREDICTED: lysine-spec (1089) 444 74.9 4e-12 XP_011526120 (OMIM: 609765) PREDICTED: lysine-spec ( 429) 436 73.6 4.1e-12 XP_016881993 (OMIM: 609765) PREDICTED: lysine-spec ( 473) 436 73.6 4.4e-12 XP_011526124 (OMIM: 609765) PREDICTED: lysine-spec ( 312) 432 72.9 4.6e-12 XP_011526123 (OMIM: 609765) PREDICTED: lysine-spec ( 330) 432 72.9 4.9e-12 >>NP_001269551 (OMIM: 300534,314690) lysine-specific dem (1559 aa) initn: 10626 init1: 10626 opt: 10626 Z-score: 7964.3 bits: 1486.5 E(85289): 0 Smith-Waterman score: 10626; 100.0% identity (100.0% similar) in 1559 aa overlap (1-1559:1-1559) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVCNTRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVCNTRPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 DNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 GPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 PEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 PKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 EKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 LEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 AEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 HSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 LAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALAC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 YDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVAL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 EVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 RVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGLL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 QSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 PSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 LKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE9 REKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLR 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE9 DPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGALQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE9 CDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILAL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE9 LVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPRP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE9 EEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSLL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE9 PQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLELE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE9 KAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEEE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 pF1KE9 TGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL 1510 1520 1530 1540 1550 >>NP_004178 (OMIM: 300534,314690) lysine-specific demeth (1560 aa) initn: 10612 init1: 9417 opt: 10614 Z-score: 7955.4 bits: 1484.8 E(85289): 0 Smith-Waterman score: 10614; 99.9% identity (99.9% similar) in 1560 aa overlap (1-1559:1-1560) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV 70 80 90 100 110 120 130 140 150 160 170 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLV-CNTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: NP_004 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE9 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE9 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE9 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE9 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE9 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE9 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE9 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE9 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE9 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE9 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE9 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE9 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE9 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE9 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE9 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE9 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE9 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE9 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE9 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE9 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE9 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE9 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE9 ETGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ETGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL 1510 1520 1530 1540 1550 1560 >>XP_005262092 (OMIM: 300534,314690) PREDICTED: lysine-s (1557 aa) initn: 10577 init1: 8139 opt: 10577 Z-score: 7927.6 bits: 1479.7 E(85289): 0 Smith-Waterman score: 10577; 99.7% identity (99.7% similar) in 1560 aa overlap (1-1559:1-1557) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV 70 80 90 100 110 120 130 140 150 160 170 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLV-CNTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_005 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE9 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE9 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE9 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE9 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE9 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE9 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE9 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE9 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE9 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE9 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE9 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE9 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE9 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE9 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE9 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE9 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE9 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE9 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE9 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE9 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_005 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGS---DLELLSSL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KE9 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL 1380 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 pF1KE9 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE 1440 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 pF1KE9 ETGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL 1500 1510 1520 1530 1540 1550 >>XP_011529127 (OMIM: 300534,314690) PREDICTED: lysine-s (1519 aa) initn: 9962 init1: 9417 opt: 9803 Z-score: 7347.9 bits: 1372.4 E(85289): 0 Smith-Waterman score: 10262; 97.3% identity (97.3% similar) in 1560 aa overlap (1-1559:1-1519) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::: ::: XP_011 DNFRFTPRIQRLNELE-----------------------------------------IVV 70 130 140 150 160 170 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLV-CNTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP 80 90 100 110 120 130 180 190 200 210 220 230 pF1KE9 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG 140 150 160 170 180 190 240 250 260 270 280 290 pF1KE9 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH 200 210 220 230 240 250 300 310 320 330 340 350 pF1KE9 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE 260 270 280 290 300 310 360 370 380 390 400 410 pF1KE9 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL 320 330 340 350 360 370 420 430 440 450 460 470 pF1KE9 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP 380 390 400 410 420 430 480 490 500 510 520 530 pF1KE9 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL 440 450 460 470 480 490 540 550 560 570 580 590 pF1KE9 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA 500 510 520 530 540 550 600 610 620 630 640 650 pF1KE9 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL 560 570 580 590 600 610 660 670 680 690 700 710 pF1KE9 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA 620 630 640 650 660 670 720 730 740 750 760 770 pF1KE9 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA 680 690 700 710 720 730 780 790 800 810 820 830 pF1KE9 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP 740 750 760 770 780 790 840 850 860 870 880 890 pF1KE9 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL 800 810 820 830 840 850 900 910 920 930 940 950 pF1KE9 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV 860 870 880 890 900 910 960 970 980 990 1000 1010 pF1KE9 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ 920 930 940 950 960 970 1020 1030 1040 1050 1060 1070 pF1KE9 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS 980 990 1000 1010 1020 1030 1080 1090 1100 1110 1120 1130 pF1KE9 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL 1040 1050 1060 1070 1080 1090 1140 1150 1160 1170 1180 1190 pF1KE9 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL 1100 1110 1120 1130 1140 1150 1200 1210 1220 1230 1240 1250 pF1KE9 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA 1160 1170 1180 1190 1200 1210 1260 1270 1280 1290 1300 1310 pF1KE9 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR 1220 1230 1240 1250 1260 1270 1320 1330 1340 1350 1360 1370 pF1KE9 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL 1280 1290 1300 1310 1320 1330 1380 1390 1400 1410 1420 1430 pF1KE9 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL 1340 1350 1360 1370 1380 1390 1440 1450 1460 1470 1480 1490 pF1KE9 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE 1400 1410 1420 1430 1440 1450 1500 1510 1520 1530 1540 1550 pF1KE9 ETGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL 1460 1470 1480 1490 1500 1510 >>XP_016885375 (OMIM: 300534,314690) PREDICTED: lysine-s (1451 aa) initn: 9800 init1: 9800 opt: 9800 Z-score: 7346.0 bits: 1371.9 E(85289): 0 Smith-Waterman score: 9800; 100.0% identity (100.0% similar) in 1438 aa overlap (1-1438:1-1438) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVCNTRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVCNTRPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 DNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 GPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 PEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 PKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 EKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 LEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 AEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 HSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 LAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALAC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 YDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVAL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 EVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 RVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGLL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 QSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 PSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 LKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE9 REKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLR 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE9 DPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGALQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE9 CDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILAL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE9 LVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPRP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE9 EEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSLL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE9 PQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEET 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE9 KAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEEE XP_016 NHQASQRESRN 1450 >>XP_011529130 (OMIM: 300534,314690) PREDICTED: lysine-s (1447 aa) initn: 9828 init1: 8592 opt: 9789 Z-score: 7337.8 bits: 1370.4 E(85289): 0 Smith-Waterman score: 9789; 99.9% identity (99.9% similar) in 1440 aa overlap (1-1439:1-1440) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV 70 80 90 100 110 120 130 140 150 160 170 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLV-CNTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE9 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE9 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE9 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE9 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE9 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE9 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE9 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE9 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE9 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE9 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE9 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE9 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE9 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE9 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE9 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE9 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE9 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE9 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE9 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE9 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE9 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEV 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE9 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE XP_011 MPLMNGD >>XP_011529129 (OMIM: 300534,314690) PREDICTED: lysine-s (1452 aa) initn: 9786 init1: 8591 opt: 9788 Z-score: 7337.0 bits: 1370.3 E(85289): 0 Smith-Waterman score: 9788; 99.9% identity (99.9% similar) in 1439 aa overlap (1-1438:1-1439) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV 70 80 90 100 110 120 130 140 150 160 170 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLV-CNTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE9 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE9 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE9 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE9 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE9 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE9 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE9 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE9 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE9 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE9 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE9 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE9 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE9 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE9 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE9 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE9 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE9 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE9 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE9 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE9 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE9 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEE 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE9 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE XP_011 TNHQASQRESRN 1450 >>XP_011529128 (OMIM: 300534,314690) PREDICTED: lysine-s (1516 aa) initn: 9927 init1: 8139 opt: 9766 Z-score: 7320.2 bits: 1367.2 E(85289): 0 Smith-Waterman score: 10225; 97.1% identity (97.1% similar) in 1560 aa overlap (1-1559:1-1516) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::: ::: XP_011 DNFRFTPRIQRLNELE-----------------------------------------IVV 70 130 140 150 160 170 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLV-CNTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_011 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP 80 90 100 110 120 130 180 190 200 210 220 230 pF1KE9 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG 140 150 160 170 180 190 240 250 260 270 280 290 pF1KE9 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH 200 210 220 230 240 250 300 310 320 330 340 350 pF1KE9 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE 260 270 280 290 300 310 360 370 380 390 400 410 pF1KE9 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL 320 330 340 350 360 370 420 430 440 450 460 470 pF1KE9 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP 380 390 400 410 420 430 480 490 500 510 520 530 pF1KE9 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL 440 450 460 470 480 490 540 550 560 570 580 590 pF1KE9 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA 500 510 520 530 540 550 600 610 620 630 640 650 pF1KE9 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL 560 570 580 590 600 610 660 670 680 690 700 710 pF1KE9 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA 620 630 640 650 660 670 720 730 740 750 760 770 pF1KE9 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA 680 690 700 710 720 730 780 790 800 810 820 830 pF1KE9 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP 740 750 760 770 780 790 840 850 860 870 880 890 pF1KE9 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL 800 810 820 830 840 850 900 910 920 930 940 950 pF1KE9 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV 860 870 880 890 900 910 960 970 980 990 1000 1010 pF1KE9 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ 920 930 940 950 960 970 1020 1030 1040 1050 1060 1070 pF1KE9 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS 980 990 1000 1010 1020 1030 1080 1090 1100 1110 1120 1130 pF1KE9 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL 1040 1050 1060 1070 1080 1090 1140 1150 1160 1170 1180 1190 pF1KE9 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL 1100 1110 1120 1130 1140 1150 1200 1210 1220 1230 1240 1250 pF1KE9 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA 1160 1170 1180 1190 1200 1210 1260 1270 1280 1290 1300 1310 pF1KE9 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR 1220 1230 1240 1250 1260 1270 1320 1330 1340 1350 1360 1370 pF1KE9 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_011 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGS---DLELLSSL 1280 1290 1300 1310 1320 1330 1380 1390 1400 1410 1420 1430 pF1KE9 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL 1340 1350 1360 1370 1380 1390 1440 1450 1460 1470 1480 1490 pF1KE9 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE 1400 1410 1420 1430 1440 1450 1500 1510 1520 1530 1540 1550 pF1KE9 ETGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLHLPCPQQPPQQQL 1460 1470 1480 1490 1500 1510 >>XP_016885377 (OMIM: 300534,314690) PREDICTED: lysine-s (1448 aa) initn: 9765 init1: 9348 opt: 9763 Z-score: 7318.3 bits: 1366.8 E(85289): 0 Smith-Waterman score: 9763; 99.8% identity (99.8% similar) in 1438 aa overlap (1-1438:1-1435) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVCNTRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVCNTRPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE9 DNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE9 GPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE9 PEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE9 PKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE9 EKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE9 LEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE9 AEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE9 HSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE9 LAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALAC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE9 YDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVAL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE9 EVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE9 RVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGLL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE9 QSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE9 PSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE9 LKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE9 REKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLR 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE9 DPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGALQ 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE9 CDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILAL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE9 LVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPRP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE9 EEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSLL :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: XP_016 EEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGS---DLELLSSLL 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KE9 PQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEET 1380 1390 1400 1410 1420 1430 1450 1460 1470 1480 1490 1500 pF1KE9 KAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEEE XP_016 NHQASQRESRN 1440 >>XP_016885378 (OMIM: 300534,314690) PREDICTED: lysine-s (1444 aa) initn: 9752 init1: 8139 opt: 9752 Z-score: 7310.1 bits: 1365.3 E(85289): 0 Smith-Waterman score: 9752; 99.7% identity (99.7% similar) in 1440 aa overlap (1-1439:1-1437) 10 20 30 40 50 60 pF1KE9 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE9 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVV 70 80 90 100 110 120 130 140 150 160 170 pF1KE9 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLV-CNTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: XP_016 EEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE9 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE9 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE9 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE9 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTEL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE9 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE9 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE9 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE9 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE9 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE9 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVA 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE9 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEVEDGRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGP 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE9 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRVAGLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGL 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE9 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASV 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE9 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQ 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE9 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHS 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE9 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDL 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE9 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGAL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE9 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE9 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPR 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE9 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGSGKRDLELLSSL ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_016 PEEPPNYPAAPASDPLREGSGKDMPKVQGLLENGDSVTSPEKVAPEEGS---DLELLSSL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KE9 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 LPQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLERIRTLLEV 1380 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 pF1KE9 EKAERHGSRARGRALERRRRRKVDRGGEGDDPAREELEPKRVRSSGPEAEEVQEEEELEE XP_016 MPLMNGD 1440 1559 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:13:42 2016 done: Sat Nov 5 19:13:45 2016 Total Scan time: 20.370 Total Display time: 0.950 Function used was FASTA [36.3.4 Apr, 2011]