Result of FASTA (omim) for
pF1KE9696
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9696, 1996 aa
1>>>pF1KE9696 1996 - 1996 aa - 1996 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1965+/-0.000393; mu= 4.9151+/- 0.025
mean_var=337.8480+/-68.347, 0's: 0 Z-trim(122.4): 313 B-trim: 263 in 2/58
Lambda= 0.069777
statistics sampled from 41462 (41904) to 41462 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.457), width: 16
Scan time: 13.730
The best scores are: opt bits E(91774)
NP_001005273 (OMIM: 602120,618205) chromodomain-he (2000) 13579 1382.6 0
XP_016879553 (OMIM: 602120,618205) chromodomain-he (2055) 13365 1361.0 0
NP_001005271 (OMIM: 602120,618205) chromodomain-he (2059) 13347 1359.2 0
XP_005256486 (OMIM: 602120,618205) chromodomain-he (2060) 13335 1358.0 0
XP_016879559 (OMIM: 602120,618205) chromodomain-he (2050) 13285 1353.0 0
XP_016879552 (OMIM: 602120,618205) chromodomain-he (2056) 12676 1291.7 0
XP_016879555 (OMIM: 602120,618205) chromodomain-he (2036) 12515 1275.5 0
XP_016879556 (OMIM: 602120,618205) chromodomain-he (2045) 12515 1275.5 0
XP_006721487 (OMIM: 602120,618205) chromodomain-he (2111) 12462 1270.1 0
XP_006721486 (OMIM: 602120,618205) chromodomain-he (2114) 12456 1269.5 0
XP_016879557 (OMIM: 602120,618205) chromodomain-he (2036) 12445 1268.4 0
XP_005256484 (OMIM: 602120,618205) chromodomain-he (2115) 12444 1268.3 0
XP_016879551 (OMIM: 602120,618205) chromodomain-he (2105) 12394 1263.3 0
XP_016879550 (OMIM: 602120,618205) chromodomain-he (2109) 12376 1261.5 0
XP_016879558 (OMIM: 602120,618205) chromodomain-he (1888) 11533 1176.6 0
NP_005843 (OMIM: 602120,618205) chromodomain-helic (1966) 11199 1143.0 0
XP_006721491 (OMIM: 602120,618205) chromodomain-he (2025) 10967 1119.6 0
XP_005256485 (OMIM: 602120,618205) chromodomain-he (2080) 10967 1119.6 0
XP_016879554 (OMIM: 602120,618205) chromodomain-he (2047) 8698 891.2 0
XP_005256488 (OMIM: 602120,618205) chromodomain-he (1185) 7500 770.4 0
NP_001284482 (OMIM: 603277,617159) chromodomain-he (1905) 7186 739.0 1.2e-211
NP_001264 (OMIM: 603277,617159) chromodomain-helic (1912) 7183 738.7 1.5e-211
NP_001350535 (OMIM: 603277,617159) chromodomain-he (1902) 6871 707.3 4.3e-202
NP_056372 (OMIM: 610771) chromodomain-helicase-DNA (1954) 5272 546.3 1.3e-153
XP_011515862 (OMIM: 214800,608892,612370) chromodo (1621) 1633 179.9 2.1e-43
XP_016869102 (OMIM: 214800,608892,612370) chromodo (2996) 1633 180.2 3.2e-43
NP_060250 (OMIM: 214800,608892,612370) chromodomai (2997) 1633 180.2 3.2e-43
XP_011515857 (OMIM: 214800,608892,612370) chromodo (3026) 1633 180.2 3.2e-43
XP_011515856 (OMIM: 214800,608892,612370) chromodo (3027) 1633 180.2 3.2e-43
XP_011515855 (OMIM: 214800,608892,612370) chromodo (3027) 1633 180.2 3.2e-43
XP_016869101 (OMIM: 214800,608892,612370) chromodo (3027) 1633 180.2 3.2e-43
XP_024306229 (OMIM: 616936) chromodomain-helicase- (2237) 1578 174.5 1.2e-41
NP_001339087 (OMIM: 616936) chromodomain-helicase- (2375) 1578 174.5 1.3e-41
XP_024306228 (OMIM: 616936) chromodomain-helicase- (2391) 1578 174.5 1.3e-41
XP_005256233 (OMIM: 616936) chromodomain-helicase- (2391) 1578 174.5 1.3e-41
NP_001339086 (OMIM: 616936) chromodomain-helicase- (2408) 1578 174.5 1.3e-41
NP_001339085 (OMIM: 616936) chromodomain-helicase- (2424) 1578 174.5 1.3e-41
XP_016879214 (OMIM: 616936) chromodomain-helicase- (2431) 1578 174.5 1.3e-41
XP_016879213 (OMIM: 616936) chromodomain-helicase- (2447) 1578 174.5 1.3e-41
NP_079410 (OMIM: 616936) chromodomain-helicase-DNA (2881) 1578 174.6 1.5e-41
XP_016879212 (OMIM: 616936) chromodomain-helicase- (2881) 1578 174.6 1.5e-41
NP_001339056 (OMIM: 616936) chromodomain-helicase- (2881) 1578 174.6 1.5e-41
XP_016879211 (OMIM: 616936) chromodomain-helicase- (2882) 1578 174.6 1.5e-41
NP_001295248 (OMIM: 616936) chromodomain-helicase- (2897) 1578 174.6 1.5e-41
XP_016879210 (OMIM: 616936) chromodomain-helicase- (2897) 1578 174.6 1.5e-41
XP_011521649 (OMIM: 616936) chromodomain-helicase- (2898) 1578 174.6 1.5e-41
XP_005256225 (OMIM: 616936) chromodomain-helicase- (2898) 1578 174.6 1.5e-41
XP_016879209 (OMIM: 616936) chromodomain-helicase- (2898) 1578 174.6 1.5e-41
XP_006721344 (OMIM: 616936) chromodomain-helicase- (2898) 1578 174.6 1.5e-41
XP_006721346 (OMIM: 616936) chromodomain-helicase- (2898) 1578 174.6 1.5e-41
>>NP_001005273 (OMIM: 602120,618205) chromodomain-helica (2000 aa)
initn: 11546 init1: 11546 opt: 13579 Z-score: 7398.9 bits: 1382.6 E(91774): 0
Smith-Waterman score: 13579; 99.8% identity (99.8% similar) in 2000 aa overlap (1-1996:1-2000)
10 20 30 40 50 60
pF1KE9 MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 GEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 ALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLG
250 260 270 280 290 300
310 320 330 340 350
pF1KE9 GKRKKGGS----SDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVL
:::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE9 GCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE9 PHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE9 HCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE9 PLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGED
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE9 DGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE9 STWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTV
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE9 KYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE9 EGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKG
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE9 GKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLN
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE9 GYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE9 GPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLN
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE9 IMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVL
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE9 IFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGG
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE9 LGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKR
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE9 KMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAI
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE9 ARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEK
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE9 LLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEG
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE9 RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWL
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE9 VRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKK
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE9 KVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAP
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KE9 SEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDE
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KE9 VPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKREDVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKREDVKG
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KE9 DRELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIW
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KE9 HRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLL
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KE9 EQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAV
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KE9 LHKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAY
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KE9 PPGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGAL
1930 1940 1950 1960 1970 1980
1980 1990
pF1KE9 VSDGLDRKEPRAGEVICIDD
::::::::::::::::::::
NP_001 VSDGLDRKEPRAGEVICIDD
1990 2000
>>XP_016879553 (OMIM: 602120,618205) chromodomain-helica (2055 aa)
initn: 13365 init1: 13365 opt: 13365 Z-score: 7282.4 bits: 1361.0 E(91774): 0
Smith-Waterman score: 13365; 100.0% identity (100.0% similar) in 1964 aa overlap (33-1996:92-2055)
10 20 30 40 50 60
pF1KE9 AADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKP
::::::::::::::::::::::::::::::
XP_016 RDRHSPPGCHLFPPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKP
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE9 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE9 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE9 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE9 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE9 RKKGGSSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKKGGSSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVA
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE9 GEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKE
430 440 450 460 470 480
430 440 450 460 470 480
pF1KE9 GVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPP
490 500 510 520 530 540
490 500 510 520 530 540
pF1KE9 LPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGRS
550 560 570 580 590 600
550 560 570 580 590 600
pF1KE9 EREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDGKSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDGKSDK
610 620 630 640 650 660
610 620 630 640 650 660
pF1KE9 RKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQSTWEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQSTWEED
670 680 690 700 710 720
670 680 690 700 710 720
pF1KE9 EMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKYETQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKYETQP
730 740 750 760 770 780
730 740 750 760 770 780
pF1KE9 RFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKG
790 800 810 820 830 840
790 800 810 820 830 840
pF1KE9 PFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFK
850 860 870 880 890 900
850 860 870 880 890 900
pF1KE9 MKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDH
910 920 930 940 950 960
910 920 930 940 950 960
pF1KE9 KLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLR
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KE9 RLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLK
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KE9 KCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMT
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KE9 KMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLA
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KE9 TADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTH
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KE9 LVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDR
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KE9 NQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLLRHHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLLRHHY
1330 1340 1350 1360 1370 1380
1330 1340 1350 1360 1370 1380
pF1KE9 EQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKR
1390 1400 1410 1420 1430 1440
1390 1400 1410 1420 1430 1440
pF1KE9 QLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVRDLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVRDLRG
1450 1460 1470 1480 1490 1500
1450 1460 1470 1480 1490 1500
pF1KE9 KTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFE
1510 1520 1530 1540 1550 1560
1510 1520 1530 1540 1550 1560
pF1KE9 HINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEG
1570 1580 1590 1600 1610 1620
1570 1580 1590 1600 1610 1620
pF1KE9 IRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVPG
1630 1640 1650 1660 1670 1680
1630 1640 1650 1660 1670 1680
pF1KE9 EMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKREDVKGDRELRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKREDVKGDRELRP
1690 1700 1710 1720 1730 1740
1690 1700 1710 1720 1730 1740
pF1KE9 GPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHDY
1750 1760 1770 1780 1790 1800
1750 1760 1770 1780 1790 1800
pF1KE9 WLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALVI
1810 1820 1830 1840 1850 1860
1810 1820 1830 1840 1850 1860
pF1KE9 EEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHKVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHKVLN
1870 1880 1890 1900 1910 1920
1870 1880 1890 1900 1910 1920
pF1KE9 QLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYPPGPYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYPPGPYA
1930 1940 1950 1960 1970 1980
1930 1940 1950 1960 1970 1980
pF1KE9 TPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALVSDGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALVSDGLD
1990 2000 2010 2020 2030 2040
1990
pF1KE9 RKEPRAGEVICIDD
::::::::::::::
XP_016 RKEPRAGEVICIDD
2050
>>NP_001005271 (OMIM: 602120,618205) chromodomain-helica (2059 aa)
initn: 11546 init1: 11546 opt: 13347 Z-score: 7272.6 bits: 1359.2 E(91774): 0
Smith-Waterman score: 13347; 99.8% identity (99.8% similar) in 1968 aa overlap (33-1996:92-2059)
10 20 30 40 50 60
pF1KE9 AADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKP
::::::::::::::::::::::::::::::
NP_001 RDRHSPPGCHLFPPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKP
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE9 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE9 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE9 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE9 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
310 320 330 340 350 360
310 320 330 340 350
pF1KE9 RKKGGS----SDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGC
:::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGC
370 380 390 400 410 420
360 370 380 390 400 410
pF1KE9 PAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPH
430 440 450 460 470 480
420 430 440 450 460 470
pF1KE9 CEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHC
490 500 510 520 530 540
480 490 500 510 520 530
pF1KE9 LNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPL
550 560 570 580 590 600
540 550 560 570 580 590
pF1KE9 QGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDG
610 620 630 640 650 660
600 610 620 630 640 650
pF1KE9 KSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQST
670 680 690 700 710 720
660 670 680 690 700 710
pF1KE9 WEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKY
730 740 750 760 770 780
720 730 740 750 760 770
pF1KE9 ETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEG
790 800 810 820 830 840
780 790 800 810 820 830
pF1KE9 HTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGK
850 860 870 880 890 900
840 850 860 870 880 890
pF1KE9 KAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGY
910 920 930 940 950 960
900 910 920 930 940 950
pF1KE9 KIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGP
970 980 990 1000 1010 1020
960 970 980 990 1000 1010
pF1KE9 HMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIM
1030 1040 1050 1060 1070 1080
1020 1030 1040 1050 1060 1070
pF1KE9 MDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIF
1090 1100 1110 1120 1130 1140
1080 1090 1100 1110 1120 1130
pF1KE9 SQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLG
1150 1160 1170 1180 1190 1200
1140 1150 1160 1170 1180 1190
pF1KE9 INLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKM
1210 1220 1230 1240 1250 1260
1200 1210 1220 1230 1240 1250
pF1KE9 MLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIAR
1270 1280 1290 1300 1310 1320
1260 1270 1280 1290 1300 1310
pF1KE9 LLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLL
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KE9 RHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRR
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KE9 QSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVR
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480 1490
pF1KE9 DLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKV
1510 1520 1530 1540 1550 1560
1500 1510 1520 1530 1540 1550
pF1KE9 QEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSE
1570 1580 1590 1600 1610 1620
1560 1570 1580 1590 1600 1610
pF1KE9 KGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVP
1630 1640 1650 1660 1670 1680
1620 1630 1640 1650 1660 1670
pF1KE9 GVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKREDVKGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKREDVKGDR
1690 1700 1710 1720 1730 1740
1680 1690 1700 1710 1720 1730
pF1KE9 ELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHR
1750 1760 1770 1780 1790 1800
1740 1750 1760 1770 1780 1790
pF1KE9 RHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQ
1810 1820 1830 1840 1850 1860
1800 1810 1820 1830 1840 1850
pF1KE9 ALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLH
1870 1880 1890 1900 1910 1920
1860 1870 1880 1890 1900 1910
pF1KE9 KVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYPP
1930 1940 1950 1960 1970 1980
1920 1930 1940 1950 1960 1970
pF1KE9 GPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALVS
1990 2000 2010 2020 2030 2040
1980 1990
pF1KE9 DGLDRKEPRAGEVICIDD
::::::::::::::::::
NP_001 DGLDRKEPRAGEVICIDD
2050
>>XP_005256486 (OMIM: 602120,618205) chromodomain-helica (2060 aa)
initn: 9381 init1: 9381 opt: 13335 Z-score: 7266.0 bits: 1358.0 E(91774): 0
Smith-Waterman score: 13335; 99.7% identity (99.7% similar) in 1969 aa overlap (33-1996:92-2060)
10 20 30 40 50 60
pF1KE9 AADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKP
::::::::::::::::::::::::::::::
XP_005 RDRHSPPGCHLFPPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKP
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE9 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE9 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE9 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE9 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
310 320 330 340 350 360
310 320 330 340 350
pF1KE9 RKKGGS----SDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGC
:::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGC
370 380 390 400 410 420
360 370 380 390 400 410
pF1KE9 PAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPH
430 440 450 460 470 480
420 430 440 450 460 470
pF1KE9 CEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHC
490 500 510 520 530 540
480 490 500 510 520 530
pF1KE9 LNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPL
550 560 570 580 590 600
540 550 560 570 580 590
pF1KE9 QGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDG
610 620 630 640 650 660
600 610 620 630 640 650
pF1KE9 KSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQST
670 680 690 700 710 720
660 670 680 690 700 710
pF1KE9 WEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKY
730 740 750 760 770 780
720 730 740 750 760 770
pF1KE9 ETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEG
790 800 810 820 830 840
780 790 800 810 820 830
pF1KE9 HTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGK
850 860 870 880 890 900
840 850 860 870 880 890
pF1KE9 KAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGY
910 920 930 940 950 960
900 910 920 930 940 950
pF1KE9 KIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGP
970 980 990 1000 1010 1020
960 970 980 990 1000 1010
pF1KE9 HMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIM
1030 1040 1050 1060 1070 1080
1020 1030 1040 1050 1060 1070
pF1KE9 MDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIF
1090 1100 1110 1120 1130 1140
1080 1090 1100 1110 1120 1130
pF1KE9 SQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLG
1150 1160 1170 1180 1190 1200
1140 1150 1160 1170 1180 1190
pF1KE9 INLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKM
1210 1220 1230 1240 1250 1260
1200 1210 1220 1230 1240 1250
pF1KE9 MLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIAR
1270 1280 1290 1300 1310 1320
1260 1270 1280 1290 1300 1310
pF1KE9 LLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLL
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KE9 RHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRR
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KE9 QSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVR
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480 1490
pF1KE9 DLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKV
1510 1520 1530 1540 1550 1560
1500 1510 1520 1530 1540 1550
pF1KE9 QEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSE
1570 1580 1590 1600 1610 1620
1560 1570 1580 1590 1600 1610
pF1KE9 KGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVP
1630 1640 1650 1660 1670 1680
1620 1630 1640 1650 1660 1670
pF1KE9 GVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKR-EDVKGD
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 GVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKRAEDVKGD
1690 1700 1710 1720 1730 1740
1680 1690 1700 1710 1720 1730
pF1KE9 RELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWH
1750 1760 1770 1780 1790 1800
1740 1750 1760 1770 1780 1790
pF1KE9 RRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLE
1810 1820 1830 1840 1850 1860
1800 1810 1820 1830 1840 1850
pF1KE9 QALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVL
1870 1880 1890 1900 1910 1920
1860 1870 1880 1890 1900 1910
pF1KE9 HKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYP
1930 1940 1950 1960 1970 1980
1920 1930 1940 1950 1960 1970
pF1KE9 PGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALV
1990 2000 2010 2020 2030 2040
1980 1990
pF1KE9 SDGLDRKEPRAGEVICIDD
:::::::::::::::::::
XP_005 SDGLDRKEPRAGEVICIDD
2050 2060
>>XP_016879559 (OMIM: 602120,618205) chromodomain-helica (2050 aa)
initn: 9017 init1: 9017 opt: 13285 Z-score: 7238.8 bits: 1353.0 E(91774): 0
Smith-Waterman score: 13285; 99.6% identity (99.6% similar) in 1965 aa overlap (33-1996:92-2050)
10 20 30 40 50 60
pF1KE9 AADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKP
::::::::::::::::::::::::::::::
XP_016 RDRHSPPGCHLFPPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKP
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE9 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE9 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE9 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE9 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE9 RKKGGSSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 RKKGGSSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKV------A
370 380 390 400 410
370 380 390 400 410 420
pF1KE9 GEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKE
420 430 440 450 460 470
430 440 450 460 470 480
pF1KE9 GVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPP
480 490 500 510 520 530
490 500 510 520 530 540
pF1KE9 LPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGRS
540 550 560 570 580 590
550 560 570 580 590 600
pF1KE9 EREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDGKSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDGKSDK
600 610 620 630 640 650
610 620 630 640 650 660
pF1KE9 RKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQSTWEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQSTWEED
660 670 680 690 700 710
670 680 690 700 710 720
pF1KE9 EMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKYETQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKYETQP
720 730 740 750 760 770
730 740 750 760 770 780
pF1KE9 RFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKG
780 790 800 810 820 830
790 800 810 820 830 840
pF1KE9 PFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFK
840 850 860 870 880 890
850 860 870 880 890 900
pF1KE9 MKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDH
900 910 920 930 940 950
910 920 930 940 950 960
pF1KE9 KLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLR
960 970 980 990 1000 1010
970 980 990 1000 1010 1020
pF1KE9 RLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLK
1020 1030 1040 1050 1060 1070
1030 1040 1050 1060 1070 1080
pF1KE9 KCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMT
1080 1090 1100 1110 1120 1130
1090 1100 1110 1120 1130 1140
pF1KE9 KMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLA
1140 1150 1160 1170 1180 1190
1150 1160 1170 1180 1190 1200
pF1KE9 TADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTH
1200 1210 1220 1230 1240 1250
1210 1220 1230 1240 1250 1260
pF1KE9 LVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDR
1260 1270 1280 1290 1300 1310
1270 1280 1290 1300 1310 1320
pF1KE9 NQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLLRHHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLLRHHY
1320 1330 1340 1350 1360 1370
1330 1340 1350 1360 1370 1380
pF1KE9 EQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKR
1380 1390 1400 1410 1420 1430
1390 1400 1410 1420 1430 1440
pF1KE9 QLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVRDLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVRDLRG
1440 1450 1460 1470 1480 1490
1450 1460 1470 1480 1490 1500
pF1KE9 KTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFE
1500 1510 1520 1530 1540 1550
1510 1520 1530 1540 1550 1560
pF1KE9 HINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEG
1560 1570 1580 1590 1600 1610
1570 1580 1590 1600 1610 1620
pF1KE9 IRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVPG
1620 1630 1640 1650 1660 1670
1630 1640 1650 1660 1670 1680
pF1KE9 EMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKR-EDVKGDRELR
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 EMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKRAEDVKGDRELR
1680 1690 1700 1710 1720 1730
1690 1700 1710 1720 1730 1740
pF1KE9 PGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHD
1740 1750 1760 1770 1780 1790
1750 1760 1770 1780 1790 1800
pF1KE9 YWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALV
1800 1810 1820 1830 1840 1850
1810 1820 1830 1840 1850 1860
pF1KE9 IEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHKVL
1860 1870 1880 1890 1900 1910
1870 1880 1890 1900 1910 1920
pF1KE9 NQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYPPGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYPPGPY
1920 1930 1940 1950 1960 1970
1930 1940 1950 1960 1970 1980
pF1KE9 ATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALVSDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALVSDGL
1980 1990 2000 2010 2020 2030
1990
pF1KE9 DRKEPRAGEVICIDD
:::::::::::::::
XP_016 DRKEPRAGEVICIDD
2040 2050
>>XP_016879552 (OMIM: 602120,618205) chromodomain-helica (2056 aa)
initn: 9381 init1: 9381 opt: 12676 Z-score: 6907.5 bits: 1291.7 E(91774): 0
Smith-Waterman score: 12708; 95.9% identity (97.0% similar) in 1959 aa overlap (1-1954:1-1941)
10 20 30 40 50 60
pF1KE9 MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 GEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 ALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLG
250 260 270 280 290 300
310 320 330 340 350
pF1KE9 GKRKKGGS----SDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVL
:::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE9 GCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE9 PHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE9 HCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE9 PLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGED
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE9 DGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE9 STWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTV
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE9 KYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE9 EGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKG
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE9 GKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLN
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE9 GYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE9 GPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLN
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE9 IMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVL
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE9 IFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGG
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE9 LGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKR
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE9 KMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAI
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE9 ARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEK
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE9 LLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEG
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE9 RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWL
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE9 VRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKK
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE9 KVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAP
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KE9 SEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDE
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KE9 VPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKR-EDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 VPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKRAEDVK
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KE9 GDRELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEI
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KE9 WHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKL
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KE9 LEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANA
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KE9 VLHKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPA
:::: . .. .: : . : .. ..:: : .: . :
XP_016 VLHK---------GKGRGGPARGRAHNAASEPAGG---VAERH------EGGRDPPASHA
1870 1880 1890 1900
1920 1930 1940 1950 1960 1970
pF1KE9 YPPGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGA
: :. .::. : :.: . ... .. .::::.
XP_016 VPNTPHRSPPSDVRAQHPQPAGQQGHGASPHTGLPAGSLRYTSGVRGGLQRRTRRGPGRR
1910 1920 1930 1940 1950 1960
1980 1990
pF1KE9 LVSDGLDRKEPRAGEVICIDD
XP_016 RRQLQPDACRVLHHSRHQRPSSACEEGEGNGGGIGVRRAGSEGAPSRGGDLYRRLTGSQA
1970 1980 1990 2000 2010 2020
>>XP_016879555 (OMIM: 602120,618205) chromodomain-helica (2036 aa)
initn: 9381 init1: 9381 opt: 12515 Z-score: 6820.0 bits: 1275.5 E(91774): 0
Smith-Waterman score: 12547; 95.8% identity (97.0% similar) in 1935 aa overlap (25-1954:5-1921)
10 20 30 40 50 60
pF1KE9 MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKEN
::::::::::::::::::::::::::::::::::::
XP_016 MEVKGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKEN
10 20 30 40
70 80 90 100 110 120
pF1KE9 KPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 GEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 ALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLG
230 240 250 260 270 280
310 320 330 340 350
pF1KE9 GKRKKGGS----SDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVL
:::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 GCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSC
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 PHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHI
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE9 HCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPR
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE9 PLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGED
530 540 550 560 570 580
600 610 620 630 640 650
pF1KE9 DGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQ
590 600 610 620 630 640
660 670 680 690 700 710
pF1KE9 STWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTV
650 660 670 680 690 700
720 730 740 750 760 770
pF1KE9 KYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYK
710 720 730 740 750 760
780 790 800 810 820 830
pF1KE9 EGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKG
770 780 790 800 810 820
840 850 860 870 880 890
pF1KE9 GKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLN
830 840 850 860 870 880
900 910 920 930 940 950
pF1KE9 GYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLL
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KE9 GPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLN
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KE9 IMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVL
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KE9 IFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGG
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170 1180 1190
pF1KE9 LGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKR
1130 1140 1150 1160 1170 1180
1200 1210 1220 1230 1240 1250
pF1KE9 KMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAI
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KE9 ARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEK
1250 1260 1270 1280 1290 1300
1320 1330 1340 1350 1360 1370
pF1KE9 LLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEG
1310 1320 1330 1340 1350 1360
1380 1390 1400 1410 1420 1430
pF1KE9 RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWL
1370 1380 1390 1400 1410 1420
1440 1450 1460 1470 1480 1490
pF1KE9 VRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKK
1430 1440 1450 1460 1470 1480
1500 1510 1520 1530 1540 1550
pF1KE9 KVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAP
1490 1500 1510 1520 1530 1540
1560 1570 1580 1590 1600 1610
pF1KE9 SEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDE
1550 1560 1570 1580 1590 1600
1620 1630 1640 1650 1660 1670
pF1KE9 VPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKR-EDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 VPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKRAEDVK
1610 1620 1630 1640 1650 1660
1680 1690 1700 1710 1720 1730
pF1KE9 GDRELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEI
1670 1680 1690 1700 1710 1720
1740 1750 1760 1770 1780 1790
pF1KE9 WHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKL
1730 1740 1750 1760 1770 1780
1800 1810 1820 1830 1840 1850
pF1KE9 LEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANA
1790 1800 1810 1820 1830 1840
1860 1870 1880 1890 1900 1910
pF1KE9 VLHKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPA
:::: . .. .: : . : .. ..:: : .: . :
XP_016 VLHK---------GKGRGGPARGRAHNAASEPAGG---VAERH------EGGRDPPASHA
1850 1860 1870 1880
1920 1930 1940 1950 1960 1970
pF1KE9 YPPGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGA
: :. .::. : :.: . ... .. .::::.
XP_016 VPNTPHRSPPSDVRAQHPQPAGQQGHGASPHTGLPAGSLRYTSGVRGGLQRRTRRGPGRR
1890 1900 1910 1920 1930 1940
1980 1990
pF1KE9 LVSDGLDRKEPRAGEVICIDD
XP_016 RRQLQPDACRVLHHSRHQRPSSACEEGEGNGGGIGVRRAGSEGAPSRGGDLYRRLTGSQA
1950 1960 1970 1980 1990 2000
>>XP_016879556 (OMIM: 602120,618205) chromodomain-helica (2045 aa)
initn: 9381 init1: 9381 opt: 12515 Z-score: 6819.9 bits: 1275.5 E(91774): 0
Smith-Waterman score: 12547; 95.8% identity (97.0% similar) in 1935 aa overlap (25-1954:14-1930)
10 20 30 40 50 60
pF1KE9 MKAADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKEN
::::::::::::::::::::::::::::::::::::
XP_016 MSDPDTPPQMTFGGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKEN
10 20 30 40
70 80 90 100 110 120
pF1KE9 KPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 GEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMSKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 ALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLG
230 240 250 260 270 280
310 320 330 340 350
pF1KE9 GKRKKGGS----SDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVL
:::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 GCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSC
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 PHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHI
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE9 HCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPR
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE9 PLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGED
530 540 550 560 570 580
600 610 620 630 640 650
pF1KE9 DGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQ
590 600 610 620 630 640
660 670 680 690 700 710
pF1KE9 STWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTV
650 660 670 680 690 700
720 730 740 750 760 770
pF1KE9 KYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYK
710 720 730 740 750 760
780 790 800 810 820 830
pF1KE9 EGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKG
770 780 790 800 810 820
840 850 860 870 880 890
pF1KE9 GKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLN
830 840 850 860 870 880
900 910 920 930 940 950
pF1KE9 GYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLL
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KE9 GPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLN
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KE9 IMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVL
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KE9 IFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGG
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170 1180 1190
pF1KE9 LGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKR
1130 1140 1150 1160 1170 1180
1200 1210 1220 1230 1240 1250
pF1KE9 KMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAI
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KE9 ARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEK
1250 1260 1270 1280 1290 1300
1320 1330 1340 1350 1360 1370
pF1KE9 LLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEG
1310 1320 1330 1340 1350 1360
1380 1390 1400 1410 1420 1430
pF1KE9 RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWL
1370 1380 1390 1400 1410 1420
1440 1450 1460 1470 1480 1490
pF1KE9 VRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKK
1430 1440 1450 1460 1470 1480
1500 1510 1520 1530 1540 1550
pF1KE9 KVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAP
1490 1500 1510 1520 1530 1540
1560 1570 1580 1590 1600 1610
pF1KE9 SEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDE
1550 1560 1570 1580 1590 1600
1620 1630 1640 1650 1660 1670
pF1KE9 VPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKR-EDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 VPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKRAEDVK
1610 1620 1630 1640 1650 1660
1680 1690 1700 1710 1720 1730
pF1KE9 GDRELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEI
1670 1680 1690 1700 1710 1720
1740 1750 1760 1770 1780 1790
pF1KE9 WHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKL
1730 1740 1750 1760 1770 1780
1800 1810 1820 1830 1840 1850
pF1KE9 LEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANA
1790 1800 1810 1820 1830 1840
1860 1870 1880 1890 1900 1910
pF1KE9 VLHKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPA
:::: . .. .: : . : .. ..:: : .: . :
XP_016 VLHK---------GKGRGGPARGRAHNAASEPAGG---VAERH------EGGRDPPASHA
1850 1860 1870 1880 1890
1920 1930 1940 1950 1960 1970
pF1KE9 YPPGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGA
: :. .::. : :.: . ... .. .::::.
XP_016 VPNTPHRSPPSDVRAQHPQPAGQQGHGASPHTGLPAGSLRYTSGVRGGLQRRTRRGPGRR
1900 1910 1920 1930 1940 1950
1980 1990
pF1KE9 LVSDGLDRKEPRAGEVICIDD
XP_016 RRQLQPDACRVLHHSRHQRPSSACEEGEGNGGGIGVRRAGSEGAPSRGGDLYRRLTGSQA
1960 1970 1980 1990 2000 2010
>>XP_006721487 (OMIM: 602120,618205) chromodomain-helica (2111 aa)
initn: 11200 init1: 11200 opt: 12462 Z-score: 6790.9 bits: 1270.1 E(91774): 0
Smith-Waterman score: 12494; 96.0% identity (97.2% similar) in 1923 aa overlap (33-1954:92-1996)
10 20 30 40 50 60
pF1KE9 AADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKP
::::::::::::::::::::::::::::::
XP_006 RDRHSPPGCHLFPPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKP
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE9 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE9 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE9 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE9 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE9 RKKGGSSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKKGGSSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVA
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE9 GEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKE
430 440 450 460 470 480
430 440 450 460 470 480
pF1KE9 GVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPP
490 500 510 520 530 540
490 500 510 520 530 540
pF1KE9 LPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGRS
550 560 570 580 590 600
550 560 570 580 590 600
pF1KE9 EREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDGKSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDGKSDK
610 620 630 640 650 660
610 620 630 640 650 660
pF1KE9 RKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQSTWEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQSTWEED
670 680 690 700 710 720
670 680 690 700 710 720
pF1KE9 EMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKYETQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKYETQP
730 740 750 760 770 780
730 740 750 760 770 780
pF1KE9 RFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKG
790 800 810 820 830 840
790 800 810 820 830 840
pF1KE9 PFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFK
850 860 870 880 890 900
850 860 870 880 890 900
pF1KE9 MKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDH
910 920 930 940 950 960
910 920 930 940 950 960
pF1KE9 KLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLR
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KE9 RLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLK
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KE9 KCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMT
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KE9 KMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLA
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KE9 TADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTH
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KE9 LVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDR
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KE9 NQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLLRHHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLLRHHY
1330 1340 1350 1360 1370 1380
1330 1340 1350 1360 1370 1380
pF1KE9 EQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKR
1390 1400 1410 1420 1430 1440
1390 1400 1410 1420 1430 1440
pF1KE9 QLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVRDLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVRDLRG
1450 1460 1470 1480 1490 1500
1450 1460 1470 1480 1490 1500
pF1KE9 KTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFE
1510 1520 1530 1540 1550 1560
1510 1520 1530 1540 1550 1560
pF1KE9 HINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEG
1570 1580 1590 1600 1610 1620
1570 1580 1590 1600 1610 1620
pF1KE9 IRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVPG
1630 1640 1650 1660 1670 1680
1630 1640 1650 1660 1670 1680
pF1KE9 EMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKR-EDVKGDRELR
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_006 EMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKRAEDVKGDRELR
1690 1700 1710 1720 1730 1740
1690 1700 1710 1720 1730 1740
pF1KE9 PGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHD
1750 1760 1770 1780 1790 1800
1750 1760 1770 1780 1790 1800
pF1KE9 YWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALV
1810 1820 1830 1840 1850 1860
1810 1820 1830 1840 1850 1860
pF1KE9 IEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHK--
1870 1880 1890 1900 1910
1870 1880 1890 1900 1910 1920
pF1KE9 NQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYPPGPY
. .. .: : . : .. ..:: : .: . : : :.
XP_006 -------GKGRGGPARGRAHNAASEPAGG---VAERH------EGGRDPPASHAVPNTPH
1920 1930 1940 1950 1960
1930 1940 1950 1960 1970 1980
pF1KE9 ATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALVSDGL
.::. : :.: . ... .. .::::.
XP_006 RSPPSDVRAQHPQPAGQQGHGASPHTGLPAGSLRYTSGVRGGLQRRTRRGPGRRRRQLQP
1970 1980 1990 2000 2010 2020
1990
pF1KE9 DRKEPRAGEVICIDD
XP_006 DACRVLHHSRHQRPSSACEEGEGNGGGIGVRRAGSEGAPSRGGDLYRRLTGSQACPSPRP
2030 2040 2050 2060 2070 2080
>>XP_006721486 (OMIM: 602120,618205) chromodomain-helica (2114 aa)
initn: 10651 init1: 10651 opt: 12456 Z-score: 6787.7 bits: 1269.5 E(91774): 0
Smith-Waterman score: 12488; 95.8% identity (97.0% similar) in 1926 aa overlap (33-1954:92-1999)
10 20 30 40 50 60
pF1KE9 AADTVILWARSKNDQLRISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKP
::::::::::::::::::::::::::::::
XP_006 RDRHSPPGCHLFPPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKP
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE9 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGE
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE9 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPM
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE9 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKMMTILGAKWREFSANNPFKGSAAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPAL
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE9 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGK
310 320 330 340 350 360
310 320 330 340 350
pF1KE9 RKKGGS----SDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGC
:::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGC
370 380 390 400 410 420
360 370 380 390 400 410
pF1KE9 PAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPH
430 440 450 460 470 480
420 430 440 450 460 470
pF1KE9 CEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHC
490 500 510 520 530 540
480 490 500 510 520 530
pF1KE9 LNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPL
550 560 570 580 590 600
540 550 560 570 580 590
pF1KE9 QGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSGEDDG
610 620 630 640 650 660
600 610 620 630 640 650
pF1KE9 KSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQST
670 680 690 700 710 720
660 670 680 690 700 710
pF1KE9 WEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKY
730 740 750 760 770 780
720 730 740 750 760 770
pF1KE9 ETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEG
790 800 810 820 830 840
780 790 800 810 820 830
pF1KE9 HTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGK
850 860 870 880 890 900
840 850 860 870 880 890
pF1KE9 KAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGY
910 920 930 940 950 960
900 910 920 930 940 950
pF1KE9 KIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGP
970 980 990 1000 1010 1020
960 970 980 990 1000 1010
pF1KE9 HMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIM
1030 1040 1050 1060 1070 1080
1020 1030 1040 1050 1060 1070
pF1KE9 MDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIF
1090 1100 1110 1120 1130 1140
1080 1090 1100 1110 1120 1130
pF1KE9 SQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLG
1150 1160 1170 1180 1190 1200
1140 1150 1160 1170 1180 1190
pF1KE9 INLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKM
1210 1220 1230 1240 1250 1260
1200 1210 1220 1230 1240 1250
pF1KE9 MLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIAR
1270 1280 1290 1300 1310 1320
1260 1270 1280 1290 1300 1310
pF1KE9 LLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYWEKLL
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KE9 RHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRR
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KE9 QSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVR
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480 1490
pF1KE9 DLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKV
1510 1520 1530 1540 1550 1560
1500 1510 1520 1530 1540 1550
pF1KE9 QEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QEFEHINGRWSMPELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSE
1570 1580 1590 1600 1610 1620
1560 1570 1580 1590 1600 1610
pF1KE9 KGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVP
1630 1640 1650 1660 1670 1680
1620 1630 1640 1650 1660 1670
pF1KE9 GVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKREDVKGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKREDVKGDR
1690 1700 1710 1720 1730 1740
1680 1690 1700 1710 1720 1730
pF1KE9 ELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELRPGPRDEPRSNGRREEKTEKPRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHR
1750 1760 1770 1780 1790 1800
1740 1750 1760 1770 1780 1790
pF1KE9 RHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQ
1810 1820 1830 1840 1850 1860
1800 1810 1820 1830 1840 1850
pF1KE9 ALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLH
1870 1880 1890 1900 1910 1920
1860 1870 1880 1890 1900 1910
pF1KE9 KVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLASKGTEPHPTPAYPP
: . .. .: : . : .. ..:: : .: . : :
XP_006 K---------GKGRGGPARGRAHNAASEPAGG---VAERH------EGGRDPPASHAVPN
1930 1940 1950 1960
1920 1930 1940 1950 1960 1970
pF1KE9 GPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVGALVS
:. .::. : :.: . ... .. .::::.
XP_006 TPHRSPPSDVRAQHPQPAGQQGHGASPHTGLPAGSLRYTSGVRGGLQRRTRRGPGRRRRQ
1970 1980 1990 2000 2010 2020
1980 1990
pF1KE9 DGLDRKEPRAGEVICIDD
XP_006 LQPDACRVLHHSRHQRPSSACEEGEGNGGGIGVRRAGSEGAPSRGGDLYRRLTGSQACPS
2030 2040 2050 2060 2070 2080
1996 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 15:48:21 2019 done: Tue Jul 16 15:48:23 2019
Total Scan time: 13.730 Total Display time: 0.990
Function used was FASTA [36.3.4 Apr, 2011]